Les récepteurs des entérotoxines bactériennes | Veterinary Research, a journal on Animal Infection

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Issue		Vet. Res. Volume 31, Number 4, July-August 2000


Page(s)		413 - 435
DOI		https://doi.org/10.1051/vetres:2000129
How to cite this article		Vet. Res. (2000) 413-435

References

1: Aktories K., Wegner A., Mechanisms of the cytopathic action of actin-ADP- ribosylating toxins, Mol. Microbiol. 6 (1992) 2905-2908.
2: Almenoff J.S., Williams S.I., Scheving L.A., Judd A.K., Schoolnik G.K., Ligand-based histochemical localization and capture of cells expressing heat-stable enterotoxin receptors, Mol. Microbiol. 8 (1993) 865-873.
3: Almenoff J.S., Jurka J., Schoolnik G.K., Induction of heat-stable enterotoxin receptor activity by a human Alu repeat, J. Biol. Chem. 269 (1994) 16610-16617.
4: Angstrom J., Teneberg S., Karlsson K.A., Delineation and comparison of ganglioside-binding epitopes for the toxins of Vibrio cholerae, Escherichia coli, and Clostridium tetani: evidence for overlapping epitopes, Proc. Natl. Acad. Sci. USA 91 (1994) 11859-11863.
5: Beachey E.H., Giampapa C.S., Abraham S.N., Bacterial adherence. Adhesin receptor-mediated attachment of pathogenic bacteria to mucosal surfaces, Am. Rev. Resp. Dis. 138 (1988) S45-S48.
6: Bell G.I., Dembo M., Bongrand P., Cell adhesion. Competition between nonspecific repulsion and specific bonding, Biophys. J. 45 (1984) 1051-1064.
7: Belmonte G., Menestrina G., Pederzolli C., Krizaj I., Gubensek F., Turk T., Macek P., Primary and secondary structure of a pore-forming toxin from the sea anemone, Actinia equina L., and its association with lipid vesicles, Biochim. Biophys. Acta 1192 (1994) 197-204.
8: Bergdoll M.S., Ileal loop fluid accumulation test for diarrheal toxins, Methods Enzymol. 165 (1988) 306-323.
9: Bernardi A., Raimondi L., Zuccotto F., Simulation of protein-sugar interactions: a computational model of the complex between ganglioside GM1 and the heat-labile enterotoxin of Escherichia coli, J. Med. Chem. 40 (1997) 1855-1862.
10: Bock K., Karlsson K.A., Stromberg N., Teneberg S., Interaction of viruses, bacteria and bacterial toxins with host cell surface glycolipids. Aspects on receptor identification and dissection of binding epitopes, Adv. Exp. Med. Biol. 228 (1988) 153-186.
11: Boyd B., Tyrrell G., Maloney M., Gyles C., Brunton J., Lingwood C., Alteration of the glycolipid binding specificity of the pig edema toxin from globotetraosyl to globotriaosyl ceramide alters in vivo tissue targetting and results in a verotoxin 1-like disease in pigs, J. Exp. Med. 177 (1993) 1745-1753.
12: Boyd B., Magnusson G., Zhiuyan Z., Lingwood C.A., Lipid modulation of glycolipid receptor function. Availability of Gal(alpha 1-4)Gal disaccharide for verotoxin binding in natural and synthetic glycolipids, Eur. J. Biochem. 223 (1994) 873-878.
13: Braden B.C., Dall'Acqua W., Eisenstein E., Fields B.A., Goldbaum F.A., Malchiodi E.L., Mariuzza R.A., Schwarz F.P., Ysern X., Poljak R.J., Protein motion and lock and key complementarity in antigen-antibody reactions, Pharmaceutica Acta Helvetica 69 (1995) 225-230.
14: Buckley J.T., The channel-forming toxin aerolysin, FEMS Med. Microbiol. Immunol. 5 (1992) 13-17.
15: Calva E., Torres J., Vazquez M., Angeles V., de la Vega H., Ruiz-Palacios G.M., Campylobacter jejuni chromosomal sequences that hybridize to Vibrio cholerae and Escherichia coli LT enterotoxin genes, Gene 75 (1989) 243-251.
16: Chakraborty T., Schmid A., Notermans S., Benz R., Aerolysin of Aeromonas sobria: evidence for formation of ion-permeable channels and comparison with alpha-toxin of Staphylococcus aureus, Infect. Immun. 58 (1990) 2127-2132.
17: Chao K.L., Dreyfus L.A., Interaction of Escherichia coli heat-stable enterotoxin B with cultured human intestinal epithelial cells, Infect. Immun. 65 (1997) 3209-3217.
18: Cheng S.H., Rich D.P., Marshall J., Gregory R.J., Welsh M.J., Smith A.E., Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel, Cell 66 (1991) 1027-1036.
19: Chopra A.K., Vo T.N., Houston C.W., Mechanism of action of a cytotonic enterotoxin produced by Aeromonas hydrophila, FEMS Microbiol. Lett. 70 (1992) 15-19.
20: Clark G.F., Krivan H.C., Wilkins T.D., Smith D.F., Toxin A from Clostridium difficile binds to rabbit erythrocyte glycolipids with terminal Gal alpha 1-3Gal beta 1-4GlcNAc sequences, Arch. Biochem. Biophys. 257 (1987) 217-229.
21: Cohen M.B., Guarino A., Shukla R., Giannella R.A., Age-related differences in receptors for Escherichia coli heat-stable enterotoxin in the small and large intestine of children, Gastroenterology 94 (1988) 367-373.
22: Cohen M.B., Thompson M.R., Giannella R.A., Differences in jejunal and ileal response to E. coli enterotoxin: possible mechanisms, Am. J. Physiol. 257 (1989) G118-G123.
23: Connell T.D., Holmes R.K., Mutational analysis of the ganglioside-binding activity of the type II Escherichia coli heat-labile enterotoxin LT-IIb, Mol. Microbiol. 16 (1995) 21-31.
24: Cowell S., Aschauer W., Gruber H.J., Nelson K.L., Buckley J.T., The erythrocyte receptor for the channel-forming toxin aerolysin is a novel glycosylphosphatidylinositol-anchored protein, Mol. Microbiol. 25 (1997) 343-350.
25: Crane J.K., Shanks K.L., Phosphorylation and activation of the intestinal guanylyl cyclase receptor for Escherichia coli heat-stable toxin by protein kinase C, Mol. Cell. Biochem. 165 (1996) 111-120.
26: Cuatrecasas P., Gangliosides and membrane receptors for cholera toxin, Biochemistry 12 (1973) 3558-3566.
27: Currie M.G., Fok K.F., Kato J., Moore J.R., Hamra F.K., Duffin K.L., Smith C.E., Guanylin: an endogenous activator of intestinal guanylate cyclase, Proc. Natl. Acad. Sci. USA 89 (1992) 947-951.
28: De Grandis S., Law H., Brunton J., Gyles C., Lingwood C.A., Globotetraosylceramide is recognized by the pig edema disease toxin, J. Biol. Chem. 264 (1989) 12520-12525.
29: De Sauvage F.J., Camerato T.R., Goeddel D.V., Primary structure and functional expression of the human receptor for Escherichia coli heat-stable enterotoxin, J. Biol. Chem. 266 (1991) 17912-17918.
30: Dimmock N.J., Review article of initial stages in infection with animal viruses, J. Gen. Virol. 59 (1982) 1-22.
31: Dreyfus L.A., Harville B., Howard D.E., Shaban R., Beatty D.M., Morris S.J., Calcium influx mediated by the Escherichia coli heat-stable enterotoxin B (ST $_{\rm B}$ ), Proc. Natl. Acad. Sci. USA 90 (1993) 3202-3206.
32: Dubreuil J.D., Escherichia coli STb enterotoxin, Microbiology 143 (1997) 1783-1795.
33: Dubreuil J.D., Enterotoxigenic Escherichia coli heat-stable toxins, in: Alouf J.E., Freer J.H. (Eds.), The comprehensive sourcebook of bacterial protein toxins, Academic Press, London, 1999, pp. 525-544.
34: Eidels L., Proia R.L., Hart D.A., Membrane receptors for bacterial toxins, Microbiol. Rev. 47 (1983) 596-620.
35: Eiklid K., Olsnes S., Interaction of Shigella shigae cytotoxin with receptors on sensitive and insensitive cells, J. Recept. Res. 1 (1980) 199-213.
36: Endo Y., Tsurugi K., Yutsudo T., Takeda Y., Ogasawara T., Igarashi K., Site of action of a Vero toxin (VT2) from Escherichia coli O157:H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins, Eur. J. Biochem. 171 (1988) 45-50.
37: Fasano A., Cellular microbiology: how enteric pathogens socialize with their intestinal host, Am. Soc. Microbiol. News 63 (1997) 259-265.
38: Fasano A., Kay B.A., Russell R.G., Maneval D.R. Jr., Levin M.M., Enterotoxin and cytotoxin production by enteroinvasive Escherichia coli, Infect. Immun. 58 (1990) 3717-3723.
39: Field M., Graf L.H., Laird W.J., Smith P.L., Heat-stable enterotoxin of Escherichia coli: in vitro effects on guanylate cyclase activity, cyclic GMP concentration, and ion transport in small intestine, Proc. Natl. Acad. Sci. USA 75 (1978) 2800-2804.
40: Fishman P.H., Role of membrane gangliosides in the binding and action of bacterial toxins, J. Membrane Biol. 69 (1982) 85-97.
41: Fishman P.H., Attikan E.E., Mechanism of action of cholera toxin: effect of receptor density and multivalent binding on activation of adenylate cyclase, J. Membrane Biol. 54 (1980) 51-60.
42: Forte L.R., Thorne P.K., Eber S.L., Krause W.J., Heeman R.H., Hancis S.H., Corbin J.D., Stimulation of intestinal Cl- transport by heat-stable enterotoxin: activation of cAMP-dependent protein kinase by cGMP, Am. J. Physiol. 263 (1992) C607-C615.
43: Forti S., Menestrina G., Staphylococcal alpha-toxin increases the permeability of lipid vesicles by cholesterol- and pH-dependent assembly of oligomeric channels, Eur. J. Biochem. 181 (1989) 767-773.
44: Frantz J.C., Jaso-Friedman L., Robertson D.C., Binding of Escherichia coli heat-stable enterotoxin to rat intestinal cells and brush border membranes, Infect. Immun. 43 (1984) 622-630.
45: Fritz G., Schroeder P., Aktories K., Isolation and characterization of a Clostridium botulinum C2 toxin-resistant cell line: evidence for possible involvement of the cellular C2II receptor in growth regulation, Infect. Immun. 63 (1995) 2334-2340.
46: Fujii Y., Kondo Y., Okamoto K., Involvement of prostaglandin E2 synthesis in the intestinal secretory action of Escherichia coli heat-stable enterotoxin II, FEMS Microbiol. Lett. 130 (1995) 259-265.
47: Fujii Y., Nomura T., Yamanaka H., Okamoto K., Involvement of Ca(2+)-calmodulin-dependent protein kinase II in the intestinal secretory action of Escherichia coli heat-stable enterotoxin II, Microbiol. Immunol. 41 (1997) 633-636.
48: Fukuta S., Magnani J.L., Twiddy E.M., Holmes R.K., Ginsburg V., Comparison of the carbohydrate-binding specificities of cholera toxin and Escherichia coli heat-labile enterotoxins LTh-I, LT-IIa, and LT-IIb, Infect. Immun. 56 (1988) 1748-1753.
49: Galen J.E., Ketley J.M., Fasano A., Richardson S.H., Wasserman S.S., Kaper J.B., Role of Vibrio cholerae neuraminidase in the function of cholera toxin, Infect. Immun. 60 (1992) 406-415.
50: Ganguly N.K., Kaur T., Mechanism of action of cholera toxin and other toxins, Indian J. Med. Res. 104 (1996) 28-37.
51: Garland W.J., Buckley J.T., The cytolytic toxin aerolysin must aggregate to disrupt erythrocytes, and aggregation is stimulated by human glycophorin, Infect. Immun. 56 (1988) 1249-1253.
52: Gemmell C.G., Comparative study of the nature and biological activities of bacterial enterotoxins, J. Med. Microbiol. 17 (1984) 217-235.
53: Giannella R.A., Luttrell M., Thompson M., Binding of Escherichia coli heat-stable enterotoxin to receptors on rat intestinal cells, Am. J. Physiol. 245 (1983) G492-G498.
54: Greenberg R.N., Hill M., Crytzer J., Krause W.J., Eber S.L., Hamra F.K., Forte L.R., Comparison of effects of uroguanylin, guanylin, and Escherichia coli heat-stable enterotoxin STa in mouse intestine and kidney: evidence that uroguanylin is an intestinal natriuretic hormone, J. Invest. Med. 45 (1997) 276-282.
55: Griffiths S.L., Critchley D.R., Characterization of the binding sites for Escherichia coli heat-labile toxin type I in intestinal brush borders, Biochim. Biophys. Acta 1075 (1991) 154-161.
56: Griffiths S.L., Finkelstein R.A., Critchley D.R., Characterization of the receptor for cholera toxin and Escherichia coli heat-labile toxin in rabbit intestinal brush borders, Biochem. J. 238 (1986) 313-322.
57: Guarino A., Cohen M., Thompson M., Dharmsathaphorn K., Giannella R., T84 cell receptor binding and guanyl cyclase activation by Escherichia coli heat-stable toxin, Am. J. Physiol. 253 (1987) G775-G780.
58: Guarino A., Cohen M.B., Overmann G., Thompson M.R., Giannella R.A., Binding of E. coli heat-stable enterotoxin to rat intestinal brush borders and to basolateral membranes, Dig. Dis. Sci. 32 (1987) 1017-1026.
59: Gyles C.L., Escherichia coli cytotoxins and enterotoxins, Can. J. Microbiol. 38 (1992) 734-746.
60: Hanna P.C., McClane B.A., A recombinant C-terminal toxin fragment provides evidence that membrane insertion is important for Clostridium perfringens enterotoxin cytoxicity, Mol. Microbiol. 5 (1991) 225-230.
61: Harville B.A., Dreyfus L.A., Release of serotonin from RBL-2H3 cells by the Escherichia coli peptide toxin STb, Peptides 17 (1996) 363-366.
62: Hildebrand A., Pohl M., Bhakdi S., Staphylococcus aureus alpha-toxin. Dual mechanism of binding to target cells, J. Biol. Chem. 266 (1991) 17195-17200.
63: Hippenstiel S., Tannert-Otto S., Vollrath N., Krull M., Just I., Aktories K., von Eichel-Streiber C., Suttorp N., Glucosylation of small GTP-binding Rho proteins disrupts endothelial barrier function, Am. J. Physiol. 272 (1997) L38-L43.
64a: Hirayama T., Wada A., Iwata N., Takasaki S., Shimonishi Y., Takeda Y., Glycoprotein receptors for a heat-stable enterotoxin (STh) produced by enterotoxigenic Escherichia coli, Infect. Immun. 60 (1992) 4213-4220.
64b: Hirst T.R., Cholera toxin and Escherichia coli enterotoxin, in: Alouf J.E., Freer J.H. (Eds.), The Comprehensive Sourcebook of Bacterial Protein Toxins, Academic Press, London, 1999, pp. 104-129.
65: Holmgren J., Lönnroth I., Mansson J.-E., Svennerholm L., Interaction of cholera toxin and membrane GM1 ganglioside of the small intestine, Proc. Natl. Acad. Sci. USA 72 (1975) 2520-2524.
66: Holmgren J., Fredman P., Lindblad M., Svennerholm A.M., Svennerholm L., Rabbit intestinal glycoprotein receptor for Escherichia coli heat-labile enterotoxin lacking affinity for cholera toxin, Infect. Immun. 38 (1982) 424-433.
67: Holmgren J., Lindblad M., Fredman P., Svennerholm L., Myrvold H., Comparison of receptors for cholera and Escherichia coli enterotoxins in human intestine, Gastroenterology 89 (1985) 27-35.
68: Huott P.A., Liu W., McRoberts J.A., Gianella R.A., Mechanism of action of Escherichia coli heat-stable enterotoxin in a human colonic cell line, J. Clin. Invest. 82 (1988) 514-523.
69: IUPAC-IUB Commission on Biochemical Nomenclature C.B.N., The nomenclature of lipids, Biochem. J. 171 (1978) 21-35.
70: IUPAC-IUB Joint Commission on Biochemical Nomenclature J.C.B.N., Nomenclature of glycoproteins, glycopeptides and peptidoglycans. Recommendations 1985, Eur. J. Biochem. 159 (1986) 1-6.
71: Jacewicz M., Clausen H., Nudelman E., Donohue-Rolfe A., Keusch G.T., Pathogenesis of shigella diarrhea. XI. Isolation of a Shigella toxin-binding glycolipid from rabbit jejunum and HeLa cells and its identification as globotriaosylceramide, J. Exp. Med. 163 (1986) 1391-1404.
72: Jacewicz M., Feldman H.A., Donohue-Rolfe A., Balasubramanian K.A., Keusch G.T., Pathogenesis of Shigella diarrhea. XIV. Analysis of shiga toxin receptors on cloned HeLa cells, J. Infect. Dis. 159 (1989) 881-889.
73: Janin J., Chothia C., The structure of protein-protein recognition sites, J. Biol. Chem. 265 (1990) 16027-16030.
74: Jemal C., Haddad J.E., Begum D., Jackson M.P., Analysis of Shiga toxin subunit association by using hybrid A polypeptides and site-specific mutagenesis, J. Bacteriol. 177 (1995) 3128-3132.
75: Jones G.W., Isaacson R.E., Proteinaceous bacterial adhesins and their receptors, Crit. Rev. Microbiol. 10 (1983) 229-260.
76: Just I., Wilm M., Selzer J., Rex G., von Eichel-Streiber C., Mann M., Aktories K., The enterotoxin from Clostridium difficile (ToxA) monoglucosylates the Rho proteins, J. Biol. Chem. 270 (1995) 13932-13936.
77: Kabat E.A., Antibody complementarity and antibody structure, J. Immunol. 141 (1988) S25-S36.
78: Kandel G., Donohue-Rolfe A., Donowitz M., Keusch G.T., Pathogenesis of Shigella diarrhea. XVI. Selective targetting of Shiga toxin to villus cells of rabbit jejunum explains the effect of the toxin on intestinal electrolyte transport, J. Clin. Invest. 84 (1989) 1509-1517.
79: Karlsson K.A., Animal glycolipids as attachment sites for microbes, Chem. Phys. Lipids 42 (1986) 153-172.
80: Karlsson K.A., Ångstrom J., Bergstrom J., Lanne B., Microbial interaction with animal cell surface carbohydrates, Acta Pathol. Microbiol. Immunol. Scand. - Supp. 100 (1992) 71-83.
81: Katahira J., Inoue N., Horiguchi Y., Matsuda M., Sugimoto N., Molecular cloning and functional characterization of the receptor for Clostridium perfringens enterotoxin, J. Cell Biol. 136 (1997) 1239-1247.
82: Katahira J., Sugiyama H., Inoue N., Horiguchi Y., Matsuda M., Sugimoto N., Clostridium perfringens enterotoxin utilizes two structurally related membrane proteins as functional receptors in vivo, J. Biol. Chem. 272 (1997) 26652-26658.
83: Katsu T., Kuroko M., Morikawa T., Sanchika K., Yamanaka H., Shinoda S., Fujita Y., Interaction of wasp venom mastoparan with biomembranes, Biochim. Biophys. Acta 1027 (1990) 185-190.
84: Keusch G.T., Donowitz M., Pathophysiological mechanisms of diarrhoeal diseases: diverse aetiologies and common mechanisms, Scand. J. Gastroenterol. - Supp. 84 (1983) 33-43.
85: Keusch, G.T., Jacewicz, M., Pathogenesis of Shigella diarrhea. VII. Evidence for a cell membrane toxin receptor involving beta 1 leads to 4-linked N-acetyl-D-glucosamine oligomers, J. Exp. Med. 146 (1977) 535-546.
86: Keusch G.T., Jacewicz M., Donohue-Rolfe A., Pathogenesis of Shigella diarrhea: evidence for an N-linked glycoprotein shigella toxin receptor and receptor modulation by ß-galactosidase, J. Infect. Dis. 153 (1986) 238-248.
87: Keusch G.T., Jacewicz M., Acheson D.W.K., Donohue-Rolfe A., Globotriaosylceramide, Gb3, is an alternative functional receptor for shiga-like toxin 2e, Infect. Immun. 63 (1995) 1138-1141.
88: Khuruna S., Ganguly N.K., Khullar M., Panigrahi D., Walia B.N., Studies on the mechanism of Salmonella typhimurium enterotoxin-induced diarrhoea, Biochim. Biophys. Acta 1097 (1991) 171-176.
89: Klipstein F.A., Engert R.F., Immunological relationship of the B subunits of Campylobacter jejuni and Escherichia coli heat-labile enterotoxins, Infect. Immun. 48 (1985) 629-633.
90: Krause W.J., Cullingford R.H., Freeman R.H., Eber S.L., Richardson K.C., Fok K.F., Currie M.G., Forte L.R.., Distribution of heat-stable enterotoxin on Cl^- secretion in human gut, J. Anat. 184 (1994) 407-417.
91: Krivan H.C., Clark G.F., Smith D.F., Wilkins T.D., Cell surface binding site for Clostridium difficile enterotoxin: evidence for a glycoconjugate containing the sequence Gal alpha 1-3Gal beta 1-4GlcNAc, Infect. Immun. 53 (1986) 573-581.
92: Kuhn M., Adermann K., Jahne J., Forssmann W.G., Rechkemmer G., Segmental differences in the effects of guanylin and Escherichia coli heat-stable enterotoxin on Cl^- secretion in human gut, J. Physiol. 479 (1994) 433-440.
93: Levis M.J., Bourne H.R., Activation of the alpha subunit of Gs in intact cells alters its abundance, rate of degradation, and membrane avidity, J. Cell Biol. 119 (1992) 1297-1307.
94: Lindberg A.A., Brown J.E., Stromberg N., Westling-Ryd M., Schultz J.E., Karlsson K.A., Identification of the carbohydrate receptor for Shiga toxin produced by Shigella dysenteriae type 1, J. Biol. Chem. 262 (1987) 1779-1785.
95: Lingwood C.A., Law H., Richardson S., Petric M., Brunton J.L., De Grandis S., Karmali M., Glycolipid binding of purified and recombinant Escherichia coli produced verotoxin in vitro, J. Biol. Chem. 262 (1987) 8834-8839.
96: Lucas F., Corthier G., Les récepteurs aux entérotoxines bactériennes, Ann. Rech. Vét. 22 (1991) 127-145.
97: Lucas F., Popoff M., Corthier G., Les entérotoxines bactériennes: structure, mode d'action, Ann. Rech. Vét. 22 (1991) 147-162.
98: Magnani J.L., Smith D.F., Ginsburg V., Detection of gangliosides that bind cholera toxin: direct binding of ¹²⁵I-labeled to thin-layer chromatograms, Anal. Biochem. 109 (1980) 399-402.
99: Mainil J., Shiga/verotoxins and shiga/verotoxigenic Escherichia coli in animals, Vet. Res. 30 (1999) 235-257.
100: Mann E.A., Cohen M.B., Giannella R.A., Comparison of receptors for Escherichia coli heat-stable enterotoxin: novel receptor present in IEC-6 cells, Am. J. Physiol. 264 (1993) G172-G178.
101: Matsuda M., Sugimoto N., Calcium-independent and dependent steps in action of Clostridium perfringens enterotoxin on HeLa and Vero cells, Biochem. Biophys. Res. Commun. 91 (1979) 629-636.
102: McClane B.A., Wnek A.P., Studies of Clostridium perfringens enterotoxin action at different temperatures demonstrate a correlation between complex formation and cytotoxicity, Infect. Immun. 58 (1990) 3109-3115.
103a: McClane B.A., Wnek A.P., Hulkower K.I., Hanna P.C., Divalent cation involvement in the action of Clostridium perfringens type A enterotoxin. Early events in enterotoxin action are divalent cation-independent, J. Biol. Chem. 263 (1988) 2423-2435.
103b: Menestrina G., Ferreras M., Alpha-toxin (Staphylococcus aureus), in: Rappuoli R., Montecucco C. (Eds.), Guidebook to protein toxins and their use in cell biology, Sambrook and Tooze publication, Oxford University Press, Great Britain, 1997, pp. 10-13.
104: Menestrina G., Bashford C.L., Pasternak C.A., Pore-forming toxins: experiments with S. aureus alpha-toxin, C. perfringens theta-toxin and E. coli haemolysin in lipid bilayers, liposomes and intact cells, Toxicon 28 (1990) 477-491.
105: Menestrina G., Schiavo G., Montecucco C., Molecular mechanisms of action of bacterial protein toxins, Mol. Aspects Med. 15 (1994) 79-193.
106: Mezoff A.G., Giannella R.A., Eade M.N., Cohen M.B., Escherichia coli enterotoxin (STa) binds to receptors stimulates guanyl cyclase, and impairs absorption in rat colon, Gastroenterology 102 (1992) 816-822.
107: Miller-Podraza H., Bradley R.M., Fishman P.H., Biosynthesis and localization of gangliosides in cultured cells, Biochemistry 21 (1982) 3260-3265.
108: Mobassaleh M., Donohue-Rolfe A., Jacewicz M., Grand R.J., Keusch G.T., Pathogenesis of shigella diarrhea: evidence for a developmentally regulated glycolipid receptor for shigella toxin involved in the fluid secretory response of rabbit small intestine, J. Infect. Dis. 157 (1988) 1023-1031.
109: Mobassaleh M., Gross S.K., McCluer R.H., Donohue-Rolfe A., Keusch G.T., Quantitation of the rabbit intestinal glycolipid receptor for Shiga toxin. Further evidence for the developmental regulation of globotriaosylceramide in microvillus membranes, Gastroenterology 97 (1989) 384-391.
110: Moniatte M., van der Goot F.G., Buckley J.T., Pattus F., van Dorsselaer A., Characterization of the heptameric pore-forming complex of the Aeromonas toxin aerolysin using MALDI-TOF mass spectrometry, FEBS Lett. 384 (1996) 269-272.
111: Moss J., Fishman P.H., Manganiello V.C., Vaughan M., Brady R.O., Functional incorporation of ganglioside into intact cells: induction of choleragen responsiveness, Proc. Natl. Acad. Sci. USA 73 (1976) 1034-1037.
112: Moss J., Garrison S., Fishman P.H., Richardson S.H., Gangliosides sensitize unresponsive fibroblasts to Escherichia coli heat-labile enterotoxin, J. Clin. Invest. 64 (1979) 381-384.
113: Nagy B., Fekete P.Z., Enterotoxigenic Escherichia coli (ETEC) in farm animals, Vet. Res. 30 (1999) 259-284.
114: Nelson K.L., Raja S.M., Buckley J.T., The glycosylphosphatidylinositol-anchored surface glycoprotein Thy-1 is a receptor for the channel-forming toxin aerolysin, J. Biol. Chem. 272 (1997) 12170-12174.
115: O 'Brien A.D., Holmes R.K., Shiga and Shiga-like toxins, Microbiol. Rev. 51 (1987) 206-220.
116: Orlandi P.A., Critchley D.R., Fishman P.H., The heat-labile enterotoxin of Escherichia coli binds to polylactosaminoglycan-containing receptors in CaCo-2 human intestinal epithelial cells, Biochemistry 33 (1994) 12886-12895.
117: Padlan E.A., Kabat E.A., Modeling of antibody combining sites, Methods Enzymol. 203 (1991) 3-21.
118: Parkinson S.J., Alekseev A.E., Gomez L.A., Wagner F., Terzic A., Waldman S.A., Interruption of Escherichia coli heat-stable enterotoxin-induced guanylyl cyclase signaling and associated chloride current in human intestinal cells by 2-chloroadenosine, J. Biol. Chem. 272 (1997) 754-758.
119: Paulson J.C., Glycoproteins: what are the sugar chains for?, Trends Biochem. Sci. 14 (1989) 272-276.
120: Pothoulakis C., LaMont J.T., Eglow R., Gao N., Rubins J.B., Theoharides T.C., Dickey B.F., Characterization of rabbit ileal receptors for Clostridium difficile toxin A. Evidence for a receptor-coupled G protein, J. Clin. Invest. 88 (1991) 119-225.
121: Pothoulakis C., Gilbert R.J., Cladaras C., Castagliuolo I., Semenza G., Hitti Y., Montcrief J.S., Linevsky J., Kelly C.P., Nikulasson S., Desai H.P., Wilkins T.D., LaMont J.T., Rabbit sucrase-isomaltase contains a functional intestinal receptor for Clostridium difficile toxin A, J. Clin. Invest. 98 (1996) 641-649.
122: Raimondi F., Kao J.P., Kaper J.B., Guandalini S., Fasano A., Calcium-dependent intestinal chloride secretion by Vibrio parahaemolyticus thermostable direct hemolysin in a rabbit model, Gastroenterology 109 (1995) 381-386.
123: Reisbig R., Olsnes S., Eiklid K., The cytotoxic activity of Shigella toxin. Evidence for catalytic inactivation of the 60 S ribosomal subunit, J. Biol. Chem. 256 (1981) 8739-8744.
124: Robins-Browne R.M., Takeda T., Fasano A., Bordun A.M., Dohi S., Kasuga H., Fang G., Prado V., Guerrant R.L., et al., Assessment of enterotoxin production by Yersinia enterocolitica and identification of a novel heat-stable enterotoxin produced by a noninvasive Y. enterocolitica strain isolated from clinical material, Infect. Immun. 61 (1993) 764-767.
125: Rousset E., Harel J., Dubreuil J.D., Binding characteristics of Escherichia coli enterotoxin b (STb) to the pig jejunum and partial characterization of the molecule involved, Microbial Pathogen. 24 (1998) 277-288.
126: Rousset E., Harel J., Dubreuil J.D., Sulfatide from the pig jejunum brush border epithelial cell surface is involved in binding of Escherichia coli enterotoxin b, Infect. Immun. 66 (1998) 5650-5658.
127: Samuel J.E., Perera L.P., Ward S., O'Brien A.D., Ginsburg V., Krivan H.C., Comparison of the glycolipid receptor specificities of Shiga-like toxin type II and Shiga-like toxin type II variants, Infect. Immun. 58 (1990) 611-618.
128: Sandvig K., Olsnes S., Brown J.E., Petersen O.W., van Deurs B., Endocytosis from coated pits of Shiga toxin: a glycolipid-binding protein from Shigella dysenteriae type 1, J. Cell Biol. 108 (1989) 1331-1343.
129: Sauerborn M., Leukel P., von Eichel-Streiber C., The C-terminal ligand-binding domain of Clostridium difficile toxin A (TcdA) abrogates TcdA-specific binding to cells and prevents mouse lethality, FEMS Microbiol. Lett. 155 (1997) 45-54.
130: Savarino S.J., Fasano A., Watson J., Martin B.M., Levine M.M., Guandalini S., Guerry P., Enteroaggregative Escherichia coli heat-stable enterotoxin 1 represents another subfamily of E. coli heat-stable toxin, Proc. Natl. Acad. Sci. USA 90 (1993) 3093-3097.
131: Schultz S., Green C.K., Yuen P.S., Garbers D.L., Guanylyl cyclase is a heat-stable enterotoxin receptor, Cell 63 (1990) 941-948.
132: Sears C.L., Kaper J.B., Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion, Microbiol. Rev. 60 (1996) 167-215.
133: Sherman S., Klein E., McClane B.A., Clostridium perfringens type A enterotoxin induces tissue damage and fluid accumulation in rabbit ileum, J. Diarrhoeal Dis. Res. 12 (1994) 200-207.
134: Shida K., Takamizawa K., Nagaoka M., Tsuji T., Osawa T., Escherichia coli heat-labile enterotoxin binds to glycosylated proteins with lactose by amino carbonyl reaction, Microbiol. Immunol. 38 (1994) 273-279.
135: Sixma T.K., Pronk S.E., Kalk K.H., Wartna E.S., van Zanten B.A., Witholt B., Hol W.G., Crystal structure of a cholera toxin-related heat-labile enterotoxin from E. coli, Nature 351 (1991) 371-377.
136: Sixma T.K., Aguirre A., Terwisscha van Scheltinga A.C., Wartna E.S., Kalk K.H., Hol W.G., Heat-labile enterotoxin crystal forms with variable A/B5 orientation. Analysis of conformational flexibility, FEBS Lett. 305 (1992) 81-85.
137: Sixma T.K., Kalk K.H., van Zanten B.A., Dauter Z., Kingma J., Witholt B., Hol W.G., Refined structure of Escherichia coli heat-labile enterotoxin, a close relative of cholera toxin, J. Mol. Biol. 230 (1993) 890-918.
138: Sixma T.K., Stein P.E., Hol W.G., Read R.J., Comparison of the B-pentamers of heat-labile enterotoxin and verotoxin-1: two structures with remarkable similarity and dissimilarity, Biochemistry 32 (1993) 191-198.
139: Smith J.A., Cooke D.L., Hyde S., Borriello S.P., Long R.G., Clostridium difficile toxin A binding to human intestinal epithelial cells, J. Med. Microbiol. 46 (1997) 953-958.
140: Spiegel S., Schlessinger J., Fishman P.H., Incorporation of fluorescent gangliosides into human fibroblasts: mobility, fate, and interaction with fibronectin, J. Cell Biol. 99 (1984) 699-704.
141: Stein P.E., Boodhoo A., Tyrrell G.J., Brunton J.L., Read R.J., Crystal structure of the cell-binding B oligomer of verotoxin-1 from E. coli, Nature 355 (1992) 748-750.
142: Sugimoto N., Takagi M., Ozutsumi K., Harada S., Matsuda M., Enterotoxin of Clostridium perfringens type A forms ion-permeable channels in a lipid bilayer membrane, Biochem. Biophys. Res. Commun. 156 (1988) 551-556.
143: Sukumar M., Rizo J., Wall M., Dreyfus L.A., Kupersztoch Y.M., Gierasch L.M., The structure of Escherichia coli heat-stable enterotoxin b by nuclear magnetic resonance and circular dichroism, Protein Sci. 4 (1995) 1718-1729.
144: Takeda Y., Enterohaemorragic Escherichia coli, World Health Statistics Quarterly 50 (1997) 74-80.
145: Takeda T., Yoshino K.-I., Ramamurthy T., Nair G.B., Heat-stable enterotoxins of Vibrio and Yersinia species, in: Alouf J.E., Freer J.H. (Eds.), The comprehensive sourcebook of bacterial protein toxins, Academic Press, London, 1999, pp. 545-556.
146a: Tang G.Q., Iida T., Yamamoto K., Honda T., A mutant toxin of Vibrio parahaemolyticus thermostable direct hemolysin which has lost hemolytic activity but retains ability to bind to erythrocytes, Infect. Immun. 62 (1994) 3299-3304.
146b: Thelestam M., Chaves-Olarte E., Moos M., von Eichel-Streiber C., Clostridial toxins acting on the cytoskeleton, in: Alouf J.E., Freer J.H. (Eds.), Comprehensive Sourcebook of Bacterial Protein Toxins, 1999, pp. 147-173.
147: Teneberg S., Lonnroth I., Torres Lopez J.F., Galili U., Halvarsson M.O., Angström J., Karlsson K.A., Molecular mimicry in the recognition of glycosphingolipids by Gal alpha 3 Gal beta 4 GlcNAc beta-binding Clostridium difficile toxin A, human natural anti alpha-galactosyl IgG and the monoclonal antibody Gal-13: characterization of a binding-active human glycosphingolipid, non-identical with the animal receptor, Glycobiology 6 (1996) 599-609.
148: Tesh V.L., O'Brien A.D., The pathogenic mechanisms of Shiga toxin and the Shiga-like toxins, Mol. Microbiol. 5 (1991) 1817-1822.
149: Thiaudiere E., Siffert O., Talbot J.C., Bolard J., Alouf J.E., Dufourcq J., The amphiphilic alpha-helix concept. Consequences on the structure of staphylococcal delta-toxin in solution and bound to lipids, Eur. J. Biochem. 195 (1991) 203-213.
150: Thurin J., Binding sites of monoclonal anti-carbohydrate antibodies, Curr. Topics Microbiol. Immunol. 139 (1988) 59-79.
151: Tomasi M., Montecucco C., Lipid insertion of cholera toxin after binding to GM1-containing liposomes, J. Biol. Chem. 256 (1981) 11177-11181.
152: Tucker K.D., Wilkins T.D., Toxin A of Clostridium difficile binds to the human carbohydrate antigens I, X, and Y, Infect. Immun. 59 (1991) 73-78.
153: Tucker K.D., Carrig P.E., Wilkins T.D., Toxin A of Clostridium difficile is a potent cytotoxin, J. Clin. Microbiol. 28 (1990) 869-871.
154: Vaandrager A.B., Schulz S., De Jonge H.R., Garbers D.L., Guanylyl cyclase is an N-linked glycoprotein receptor that accounts for multiple heat-stable enterotoxin-binding proteins in the intestine, J. Biol. Chem. 268 (1993) 2174-2179.
155: van den Akker F., Sarfaty S., Twiddy E.M., Connell T.D., Holmes R.K., Hol W.G., Crystal structure of a new heat-labile enterotoxin, LT-IIb, Structure 4 (1996) 665-678.
156: van Heyningen W.E., Carpenter C.C.J., Pierce N.F., Greenough III W.B., Induction of cholera toxin by ganglioside., J. Infect. Dis. 124 (1971) 415-418.
157: Wada A., Hirayama T., Kitaura H., Fujisawa J., Hasegawa M., Hidaka Y., Shimonishi Y., Identification of ligand recognition sites in heat-stable enterotoxin receptor, membrane-associated guanylyl cyclase C by site-directed mutational analysis, Infect. Immun. 64 (1996) 5144-5150.
158: Waddell T., Head S., Petric M., Cohen A., Lingwood C., Globotriosyl ceramide is specifically recognized by the Escherichia coli verocytotoxin 2, Biochem. Biophys. Res. Commun. 152 (1988) 674-679.
159: Waddell T., Cohen A., Lingwood C., Reconstitution of verotoxin sensitivity in receptor-deficient cell lines using the receptor glycolipid globotriosylceramide, Proc. Natl. Acad. Sci. USA 87 (1990) 7898-7901.
160: Weikel C.S., Sando J.J., Guerrant R.L., Stimulation of porcine jejunal ion secretion in vivo by protein kinase-C activators, J. Clin. Invest. 76 (1985) 2430-2435.
161: Wilmsen H.U., Leonard K.R., Tichelaar W., Buckley J.T., Pattus F., The aerolysin membrane channel is formed by heptamerization of the monomer, EMBO J. 11 (1992) 2457-2463.
162: Wnek A.P., McClane B.A., Comparison of receptors for Clostridium perfringens type A and cholera enterotoxins in isolated rabbit intestinal brush border membranes, Microb. Pathog. 1 (1986) 89-100.
163: Wnek A.P., McClane B.A., Preliminary evidence that Clostridium perfringens type A enterotoxin is present in a 160,000-Mr complex in mammalian membranes, Infect. Immun. 57 (1989) 574-581.
164: Yamamoto T., Wakisaka N., Sato F., Kato A., Comparison of the nucleotide sequence of enteroaggregative Escherichia coli heat-stable enterotoxin 1 genes among diarrhea-associated Escherichia coli, FEMS Microbiol. Lett. 147 (1997) 89-95.
165: Yoh M., Morinaga N., Noda M., Honda T., The binding of Vibrio parahaemolyticus ¹²⁵I-labeled thermostable direct hemolysin to erythrocytes, Toxicon 33 (1995) 651-657.
166: Zemelman B.V., Chu S.H., Walker W.A., Host response to Escherichia coli heat-labile enterotoxin via two microvillus membrane receptors in the rat intestine, Infect. Immun. 57 (1989) 2947-2952.

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