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Table I.
Cross-species comparison of MR1 nucleotide sequence. Comparison of ovine (Ov), bovine (Bo), murine (Mu), and human (Hu) MR1 sequences show a high percentage identity when α1, α2 and α3 domains are compared across species.
| Sequences compared | Leader (55 bp) in % | α1 (261 bp) in % | α2 (276 bp) in % | α3 (276 bp) in % | TM (< 105 bp) in % | Cyt (> 40 bp) in % |
|---|---|---|---|---|---|---|
| Ov:Bo | 100 | 97 | 95 | 96 | 94 | 95 |
| Ov:Mu | 76 | 79 | 86 | 75 | 58 | 55 |
| Ov:Hu | 82 | 84 | 88 | 83 | 79 | 75 |
| Bo:Mu | 76 | 78 | 86 | 76 | 58 | 58 |
| Bo:Hu | 82 | 83 | 88 | 84 | 80 | 73 |
| Hu:Mu | 73 | 86 | 87 | 82 | 64 | 65 |