Physiology, pathogenicity and immunogenicity of lon and/or cpxR deleted mutants of Salmonella Gallinarum as vaccine candidates for fowl typhoid | Veterinary Research, a journal on Animal Infection

Open Access

Table I.

Internalization of the Salmonella Gallinarum wild type and lon, cpxR, and lon/cpxR mutants in the chicken abdominal macrophages determined by the gentamicin protection assay.

Strain	Genotype	Internalization (Log₁₀ cfu/mL)^{^a}
JOL394	Wild type	3.32 ± 0.03
JOL914	Δlon	4.05 ± 0.02^{^b}
JOL915	ΔcpxR	3.07 ± 0.09^{^c}
JOL916	ΔlonΔcpxR	3.81 ± 0.03^{^b}

Number of intracellular bacteria in chicken abdominal macrophage after exposure with m.o.i. of 10 for 60 min and killing of extracellular bacteria by gentamicin for 30 min (mean ± SEM).

Significant difference between JOL394 (p < 0.001).

Not significant difference between JOL394 (p = 0.057).