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Figure 3.


Phosphorylation of ERK1/2 (A, C) and P38 (B, D) MAPK in bovine neutrophils. fMLP induced significant phosophorylation of ERK1/2 (A) and P38 (B) MAPK within 5 min of exposure. RGDSK/K RNT significantly suppressed phosophorylation of ERK1/2 (C) and p38 (D) MPAK within 5 min of treatment. The phosphorylation of ERK1/2 (C) and p38 (MAPK) returned to control values at 10 min and remained so till 60 min. Results of three independent experiments are represented as mean ± SEM. Significant differences between treatment groups are expressed by different letters above bars (p < 0.001 and p < 0.01 for ERK and P38, respectively).

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