Comparative analysis of canine monocyte- and bone-marrow-derived dendritic cells | Veterinary Research, a journal on Animal Infection

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Table II.

Up regulation of MHC II and CD86 upon TLR ligation.

		P3C^c		PIC^c		LPS^c		Imi^c		CpG odn^c
		fi^a	p ^b	fi	p	fi	p	fi	p	fi	p
MoDC	CD86	3.6	0.048	3.9	0.003	3.2	0.038	1.1	0.3	2.6	0.14
MoDC	MHC II	2.0	0.019	2.4	0.012	2.1	0.018	1.4	0.029	1.6	0.2
FL-BMDC	CD86	4.7	0.046	3.9	0.047	3.6	0.037	3.2	0.039	2.1	0.11
FL-BMDC	MHC II	2.1	0.008	2.0	0.001	2.5	0.008	2.2	0.009	1.2	0.2
GM-BMDC	CD86	1.8	0.08	1.5	0.04	1.5	0.02	1.3	0.07	0.9	0.28
GM-BMDC	MHC II	1.8	0.049	1.6	0.039	1.6	0.001	1.4	0.046	0.9	0.81

Average fold increase of mean fluorescent intensity (MFI) calculated as MFI of stimulated cells/MFI of unstimulated cells (n = 5).

p value determined by one-sample t-test.

P3C = Pam3Cys; PIC = Polyinosinic-Polycytidylic; Imi = Imiquimod; and CpG odn = CpG oligonucleotide ODN 2395.