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Table IV.

Estimation of transmission parameters with 95% confidence intervals, based on different assumptions on the infectious period of pigs.

Transmission parameter Virus strain and inoculation dose1
Zoelen – 105 TCID50 Paderborn middle – 103.5 TCID50 Paderborn high – 105 TCID50 Brescia – 102.5 TCID50
β (day−1)
Assumption 1 (faeces)2 0c (0–2.74) 5.38b (2.11–12.2) 2.83b,c (1.17–5.84) 27.5a (10.2–63.0)
Assumption 2 (OPF/faeces)3 0c (0–0.144) 5.38a (2.11–12.2) 1.62b (0.685–3.23) 2.07a,b (0.881–4.05)
Assumption 3 (viraemia)4 0b (0–0.203) 3.23a (1.33–6.74) 1.14a (0.486–2.24) 3.00a (1.27–5.96)
Ti (day)
Assumption 1 (faeces) 5 (– – –) 26.2a (17.4–42.6) 21.2a (13.4–34.5) 7.39b (5.54–9.99)
Assumption 2 (OPF/faeces) 6.33b (4.69–8.69) 27.5a (18.4–43.7) 22.2a (16.2–31.9) 8.47b (6.17–11.8)
Assumption 3 (viraemia) (– – –) 24.4a (17.5–36.8) 21.8a (16.7–30.3) 8.38b (6.34–11.2)
SD6 of Ti (day)
Assumption 1 (faeces) (– – –) 12.8a (7.33–21.6) 13.0a (8.14–20.9) 3.22b (2.15–5.67)
Assumption 2 (OPF/faeces) 1.23b (0.648–3.82) 13.2a (7.63–21.8) 9.32a (5.81–16.5) 4.06b (2.71–7.11)
Assumption 3 (viraemia) (– – –) 10.6a (6.27–18.9) 7.99a (4.90–14.8) 3.54b (2.36–6.13)
R0
Assumption 1 (faeces) (– – –) 141a (50.6–367) 60.0a (22.5–145) 203a (73.2–488)
Assumption 2 (OPF/faeces) 0c (0–0.925) 148a (53.8–382) 35.9b (14.5–77.6) 17.5b (7.13–36.9)
Assumption 3 (viraemia) (– – –) 78.8a (30.7–181) 24.8a (10.2–52.0) 25.1a (10.3–52.8)
a–c

Means within rows with no common superscript differ significantly.

1

Pigs from the low inoculation dose trial (102 TCID50) were not included in the table since none of the pigs were infected.

2

Start and end of the infectious period coincided with virus excretion in faeces.

3

Start and end of the infectious period coincided with virus excretion in faeces and/or oropharyngeal fluid.

4

Start and end of the infectious period coincided with viraemia.

5

The 95% interval could not be determined due to lack of (variation in) data.

6

Standard deviation.