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Molecular Insights Into MR1‐Mediated T Cell Immunity: Lessons Learned and Unanswered Questions
Wael Awad, Mohamed R. Abdelaal, Victoria Letoga, James McCluskey and Jamie Rossjohn Immunological Reviews 331(1) (2025) https://doi.org/10.1111/imr.70033
MAIT cell-MR1 reactivity is highly conserved across multiple divergent species
Matthew D. Edmans, Timothy K. Connelley, Sophie Morgan, Troi J. Pediongco, Siddharth Jayaraman, Jennifer A. Juno, Bronwyn S. Meehan, Phoebe M. Dewar, Emmanuel A. Maze, Eduard O. Roos, Basudev Paudyal, Jeffrey Y.W. Mak, Ligong Liu, David P. Fairlie, Huimeng Wang, Alexandra J. Corbett, James McCluskey, Lindert Benedictus, Elma Tchilian, Paul Klenerman and Sidonia B.G. Eckle Journal of Biological Chemistry 300(6) 107338 (2024) https://doi.org/10.1016/j.jbc.2024.107338
Comprehensive phenotyping of peripheral blood monocytes in healthy bovine
Francesco Grandoni, Maria Carmela Scatà, Alessandra Martucciello, et al. Cytometry Part A 101(2) 122 (2022) https://doi.org/10.1002/cyto.a.24492
Identification and Phenotype of MAIT Cells in Cattle and Their Response to Bacterial Infections
A subset of cytotoxic effector memory T cells enhances CAR T cell efficacy in a model of pancreatic ductal adenocarcinoma
Vanaja Konduri, Sujith K. Joseph, Tiara T. Byrd, Zeid Nawas, Jonathan Vazquez-Perez, Colby J. Hofferek, Matthew M. Halpert, Dongliang Liu, Zhengdong Liang, Yunyu Baig, Vita S. Salsman, Damilola Oyewole-Said, Anna Tsimelzon, Briana A. Burns, Changyi Chen, Jonathan M. Levitt, Qizhi Yao, Nabil M. Ahmed, Meenakshi Hegde and William K. Decker Science Translational Medicine 13(592) (2021) https://doi.org/10.1126/scitranslmed.abc3196
Methods in isolation and characterization of bovine monocytes and macrophages
F. Ceciliani, G. Ávila Morales, G. De Matteis, F. Grandoni, R. Furioso Ferreira, P. Roccabianca and C. Lecchi Methods 186 22 (2021) https://doi.org/10.1016/j.ymeth.2020.06.017
Matthew D. Edmans, Timothy K. Connelley, Siddharth Jayaraman, Christina Vrettou, Martin Vordermeier, Jeffrey Y. W. Mak, Ligong Liu, David P. Fairlie, Emmanuel Atangana Maze, Tiphany Chrun, Paul Klenerman, Sidonia B. G. Eckle, Elma Tchilian and Lindert Benedictus (2020) https://doi.org/10.1101/2020.11.09.374678
MR1-Restricted T Cells with MAIT-like Characteristics Are Functionally Conserved in the Pteropid Bat Pteropus alecto
Edwin Leeansyah, Ying Ying Hey, Wan Rong Sia, Justin Han Jia Ng, Muhammad Yaaseen Gulam, Caroline Boulouis, Feng Zhu, Matae Ahn, Jeffrey Y.W. Mak, David P. Fairlie, Andrea Lay Hoon Kwa, Johan K. Sandberg and Lin-Fa Wang iScience 23(12) 101876 (2020) https://doi.org/10.1016/j.isci.2020.101876
Recognition of Vitamin B Precursors and Byproducts by Mucosal Associated Invariant T Cells
Sidonia B.G. Eckle, Alexandra J. Corbett, Andrew N. Keller, et al. Journal of Biological Chemistry 290(51) 30204 (2015) https://doi.org/10.1074/jbc.R115.685990
Mucosal-Associated Invariant T Cells in Multiple Sclerosis: The Jury is Still Out
MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage
Marielle C. Gold, James E. McLaren, Joseph A. Reistetter, et al. Journal of Experimental Medicine 211(8) 1601 (2014) https://doi.org/10.1084/jem.20140507
Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRβ repertoire
The molecular basis for Mucosal-Associated Invariant T cell recognition of MR1 proteins
Jacinto López-Sagaseta, Charles L. Dulberger, James E. Crooks, et al. Proceedings of the National Academy of Sciences 110(19) (2013) https://doi.org/10.1073/pnas.1222678110
Exceptionally high conservation of the MHC class I-related gene, MR1, among mammals
Human thymic MR1-restricted MAIT cells are innate pathogen-reactive effectors that adapt following thymic egress
M C Gold, T Eid, S Smyk-Pearson, Y Eberling, G M Swarbrick, S M Langley, P R Streeter, D A Lewinsohn and D M Lewinsohn Mucosal Immunology 6(1) 35 (2013) https://doi.org/10.1038/mi.2012.45
MR1B, a natural spliced isoform of the MHC‐related 1 protein, is expressed as homodimers at the cell surface and activates MAIT cells
NKT and MAIT invariant TCRα sequences can be produced efficiently by VJ gene recombination
Hui Yee Greenaway, Benedict Ng, David A. Price, Daniel C. Douek, Miles P. Davenport and Vanessa Venturi Immunobiology 218(2) 213 (2013) https://doi.org/10.1016/j.imbio.2012.04.003
MAIT cells, surveyors of a new class of antigen: development and functions
Endogenous MHC-Related Protein 1 Is Transiently Expressed on the Plasma Membrane in a Conformation That Activates Mucosal-Associated Invariant T Cells
Wei-Jen Chua, Sojung Kim, Nancy Myers, Shouxiong Huang, Lawrence Yu, Daved H Fremont, Michael S Diamond and Ted H Hansen The Journal of Immunology 186(8) 4744 (2011) https://doi.org/10.4049/jimmunol.1003254
Mucosal-associated invariant T cells: unconventional development and function