Free Access
Issue |
Vet. Res.
Volume 32, Number 3-4, May-August 2001
Mechanisms of resistance to antibiotics in animal and zoonotic pathogens
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Page(s) | 291 - 300 | |
DOI | https://doi.org/10.1051/vetres:2001105 | |
How to cite this article | Vet. Res. (2001) 291-300 |
- Alekshun M.N., Levy S.B., Regulation of chromosomally mediated multiple antibiotic resistance: the mar regulon, Antimicrob. Agents Chemother. 41 (1997) 2067-2075 [PubMed].
- Alekshun M.N., Levy S.B., The mar regulon: multiple resistance to antibiotics and other toxic chemicals, Trends Microbiol. 7 (1999) 410-413 [CrossRef] [PubMed].
- Ariza R.R., Cohen S.P., Bachhawat N., Levy S.B., Demple B., Repressor mutations in the marRAB operon that activate oxidative stress genes and multiple antibiotic resistance in Escherichia coli, J. Bacteriol. 176 (1994) 143-148 [PubMed].
- Bagel S., Hullen V., Wiedemann B., Heisig P., Impact of gyrA and parC mutations on quinolone resistance, doubling time, and supercoiling degree of Escherichia coli, Antimicrob. Agents Chemother. 43 (1999) 868-875 [PubMed].
- Barbosa T.M., Levy S.B., Differential expression of over 60 chromosomal genes in Escherichia coli by constitutive expression of MarA, J. Bacteriol. 182 (2000) 3467-3474 [CrossRef] [PubMed].
- Brown J.C., Thomson C.J., Amyes S.G.B., Mutations of the gyrA gene of clinical isolates of Salmonella typhimurium and three other Salmonella species leading to decreased susceptibilities to 4-quinolone drugs, J. Antimicrob. Chemother. 37 (1996) 351-356 [CrossRef] [PubMed].
- Chapman J.S., Georgopapadakou N.H., Routes of quinolone permeation in Escherichia coli, Antimicrob. Agents Chemother. 32 (1988) 438-442 [PubMed].
- Cohen S.P., McMurry L.M., Levy S.B., marA locus causes decreased expression of OmpF porin in multiple-antibiotic-resistant (Mar) mutants of Escherichia coli, J. Bacteriol. 170 (1988) 5416-5422 [PubMed].
- Cohen S.P., McMurry L.M., Hooper D.C., Wolfson J.S., Levy S.B., Cross-resistance to fluoroquinolones in multiple-antibiotic-resistant (Mar) Escherichia coli selected by tetracycline or chloramphenicol: decreased drug accumulation associated with membrane changes in addition to OmpF reduction, Antimicrob. Agents Chemother. 33 (1989) 1318-1325 [PubMed].
- Cohen S.P., Hachler H., Levy S.B., Genetic and functional analysis of the multiple antibiotic resistance (mar) locus in Escherichia coli, J. Bacteriol. 175 (1993) 1484-1492 [PubMed].
- Cohen S.P., Yan W., Levy S.B., A multidrug resistance regulatory chromosomal locus is widespread among enteric bacteria, J. Infect. Dis. 168 (1993) 484-488 [PubMed].
- del Mar Tavio M., Vila J., Ruiz J., Martin-Sanchez A.M., Jimenez de Anta M.T., Mechanisms involved in the development of resistance to fluoroquinolones in Escherichia coli isolates, J. Antimicrob. Chemother. 44 (1999) 735-742 [CrossRef] [PubMed].
- Denis A., Moreau N.J., Mechanisms of quinolone resistance in clinical isolates: accumulation of sparfloxacin and of fluoroquinolones of various hydrophobicity, and analysis of membrane composition, J. Antimicrob. Chemother. 32 (1993) 379-392 [CrossRef] [PubMed].
- Everett M.J., Jin Y.F., Ricci V., Piddock L.J.V., Contributions of individual mechanisms to fluoroquinolone resistance in 36 Escherichia coli strains isolated from humans and animals, Antimicrob. Agents Chemother. 40 (1996) 2380-2386 [PubMed].
- Fralick J.A., Evidence that TolC is required for functioning of the Mar/AcrAB efflux pump of Escherichia coli, J. Bacteriol. 178 (1996) 5803-5805 [PubMed].
- Gensberg K., Jin Y.F., Piddock L.J.V., A novel gyrB mutation in a fluoroquinolone-resistant clinical isolate of Salmonella typhimurium, FEMS Microbiol. Lett. 132 (1995) 57-60 [PubMed].
- Giraud E., Brisabois A., Martel J.L., Chaslus-Dancla E., Comparative studies of mutations in animal isolates and experimental in vitro- and in vivo-selected mutants of Salmonella spp. suggest a counterselection of highly fluoroquinolone-resistant strains in the field, Antimicrob. Agents Chemother. 43 (1999) 2131-2137 [PubMed].
- Giraud E., Cloeckaert A., Kerboeuf D., Chaslus-Dancla E., Evidence for active efflux as the primary mechanism of resistance to ciprofloxacin in Salmonella enterica serovar Typhimurium, Antimicrob. Agents Chemother. 44 (2000) 1223-1228 [CrossRef] [PubMed].
- Giraud E., Leroy-Sétrin S., Flaujac G., Cloeckaert A., Dho-Moulin M., Chaslus-Dancla E., Characterization of high-level fluoroquinolone resistance in Escherichia coli O78:K80 isolated from turkeys, J. Antimicrob. Chemother. 47 (2001) 341-343 [CrossRef] [PubMed].
- Griggs D.J., Hall M.C., Jin Y.F., Piddock L.J.V., Quinolone resistance in veterinary isolates of salmonella, J. Antimicrob. Chemother. 33 (1994) 1173-1189 [CrossRef] [PubMed].
- Griggs D.J., Gensberg K., Piddock L.J.V., Mutations in gyrA gene of quinolone-resistant Salmonella serotypes isolated from humans and animals, Antimicrob. Agents Chemother. 40 (1996) 1009-1013 [PubMed].
- Hancock R.E., The bacterial outer membrane as a drug barrier, Trends Microbiol. 5 (1997) 37-42 [CrossRef] [PubMed].
- Heisig P., High-level fluoroquinolone resistance in a Salmonella typhimurium isolate due to alterations in both gyrA and gyrB genes, J. Antimicrob. Chemother. 32 (1993) 367-377 [CrossRef] [PubMed].
- Heisig P., Genetic evidence for a role of parC mutations in development of high-level fluoroquinolone resistance in Escherichia coli, Antimicrob. Agents Chemother. 40 (1996) 879-885 [PubMed].
- Heisig P., Kratz B., Halle E., Graser Y., Altwegg M., Rabsch W., Faber J.P., Identification of DNA gyrase A mutations in ciprofloxacin-resistant isolates of Salmonella typhimurium from men and cattle in Germany, Microb. Drug Resist. 1 (1995) 211-218 [PubMed].
- Heurtin-Le Corre C., Donnio P.Y., Perrin M., Travert M.F., Avril J.L., Increasing incidence and comparison of nalidixic acid-resistant Salmonella enterica subsp. enterica serotype Typhimurium isolates from humans and animals, J. Clin. Microbiol. 37 (1999) 266-269 [PubMed].
- Imberechts H., D'hooghe I., Bouchet H., Godard C., Pohl P., Apparent loss of enrofloxacin resistance in bovine Salmonella typhimurium strains isolated in Belgium, 1991 to 1998, Vet. Rec. 147 (2000) 76-77 [PubMed].
- Kern W.V., Oethinger M., Jellen-Ritter A.S., Levy S.B., Non-target gene mutations in the development of fluoroquinolone resistance in Escherichia coli, Antimicrob. Agents Chemother. 44 (2000) 814-820 [CrossRef] [PubMed].
- Kopytek S.J., Dyer J.C.D., Knapp G.S., Hu J.C., Resistance to methotrexate due to AcrAB-dependent export from Escherichia coli, Antimicrob. Agents Chemother. 44 (2000) 3210-3212 [CrossRef] [PubMed].
- Koronakis V., Sharff A., Koronakis E., Luisi B., Hughes C., Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export, Nature 405 (2000) 914-919 [CrossRef] [PubMed].
- Koutsolioutsou A., Martins E.A., White D.G., Levy S.B., Demple B., A soxRS-constitutive mutation contributing to antibiotic resistance in a clinical isolate of Salmonella enterica (serovar Typhimurium), Antimicrob. Agents Chemother. 45 (2001) 38-43 [CrossRef] [PubMed].
- Kumagai Y., Kato J., Hoshino K., Akasaka T., Sato K., Ikeda H., Mutants of Escherichia coli DNA topoisomerase IV parC gene, Antimicrob. Agents Chemother. 40 (1996) 710-714 [PubMed].
- Kunonga N.I., Sobieski R.J., Crupper S.S., Prevalence of the multiple antibiotic resistance operon (marRAB) in the genus Salmonella, FEMS Microbiol. Lett. 187 (2000) 155-160 [PubMed].
- Lacroix F.J., Cloeckaert A., Grépinet O., Pinault C., Popoff M.Y., Waxin H., Pardon P., Salmonella typhimurium acrB-like gene: identification and role in resistance to biliary salts and detergents and in murine infection, FEMS Microbiol. Lett. 135 (1996) 161-167 [PubMed].
- Lee A., Mao W., Warren M.S., Mistry A., Hoshino K., Okumura R., Ishida H., Lomovskaya O., Interplay between efflux pumps may provide either additive or multiplicative effects on drug resistance, J. Bacteriol. 182 (2000) 3142-3150 [CrossRef] [PubMed].
- Li X.Z., Zhang L., Poole K., Interplay between the MexA-MexB-OprM multidrug efflux system and the outer membrane barrier in the multiple antibiotic resistance of Pseudomonas aeruginosa, J. Antimicrob. Chemother. 45 (2000) 433-436 [CrossRef] [PubMed].
- Linde H.J., Notka F., Metz M., Kochanowsky B., Heisig P., Lehn N., In vivo increase in resistance to ciprofloxacin in Escherichia coli associated with deletion of the C-terminal part of MarR, Antimicrob. Agents Chemother. 44 (2000) 1865-1868 [CrossRef] [PubMed].
- Lomovskaya O., Lee A., Hoshino K., Ishida H., Mistry A., Warren M.S., Boyer E., Chamberland S., Lee V.J., Use of a genetic approach to evaluate the consequences of inhibition of efflux pumps in Pseudomonas aeruginosa, Antimicrob. Agents Chemother. 43 (1999) 1340-1346 [PubMed].
- Lomovskaya O., Warren M.S., Lee A., Galazzo J., Fronko R., Lee M., Blais J., Cho D., Chamberland S., Renau T., Leger R., Hecker S., Watkins W., Hoshino K., Ishida H., Lee V.J., Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy, Antimicrob. Agents Chemother. 45 (2001) 105-116 [CrossRef] [PubMed].
- Ma D., Cook D.N., Alberti M., Pon N.G., Nikaido H., Hearst J.E., Genes acrA and acrB encode a stress-induced efflux system of Escherichia coli, Mol. Microbiol. 16 (1995) 45-55 [PubMed].
- Ma D., Alberti M., Lynch C., Nikaido H., Hearst J.E., The local repressor AcrR plays a modulating role in the regulation of acrAB genes of Escherichia coli by global stress signals, Mol. Microbiol. 19 (1996) 101-112 [PubMed].
- Maneewannakul K., Levy S.B., Identification of mar mutants among quinolone-resistant clinical isolates of Escherichia coli, Antimicrob. Agents Chemother. 40 (1996) 1695-1698 [PubMed].
- Mazzariol A., Cornaglia G., Nikaido H., Contributions of the AmpC -lactamase and the AcrAB multidrug efflux system in intrinsic resistance of Escherichia coli K-12 to -lactams, Antimicrob. Agents Chemother. 44 (2000) 1387-1390 [CrossRef] [PubMed].
- Mazzariol A., Tokue Y., Kanegawa T.M., Cornaglia G., Nikaido H., High-level fluoroquinolone-resistant clinical isolates of Escherichia coli overproduce multidrug efflux protein AcrA, Antimicrob. Agents Chemother. 44 (2000) 3441-3443 [CrossRef] [PubMed].
- Michea-Hamzehpour M., Furet Y.X., Pechere J.C., Role of protein D2 and lipopolysaccharide in diffusion of quinolones through the outer membrane of Pseudomonas aeruginosa, Antimicrob. Agents Chemother. 35 (1991) 2091-2097 [PubMed].
- Miller P.F., Sulavik M.C., Overlaps and parallels in the regulation of intrinsic multiple-antibiotic resistance in Escherichia coli, Mol. Microbiol. 21 (1996) 441-448 [PubMed].
- Mitsuyama J., Itoh Y., Takahata M., Okamoto S., Yasuda T., In vitro antibacterial activities of tosufloxacin against and uptake of tosufloxacin by outer membrane mutants of Escherichia coli, Proteus mirabilis, and Salmonella typhimurium, Antimicrob. Agents Chemother. 36 (1992) 2030-2036 [PubMed].
- Moken M.C., McMurry L.M., Levy S.B., Selection of multiple-antibiotic-resistant (Mar) mutants of Escherichia coli by using the disinfectant pine oil: roles of the mar and acrAB loci, Antimicrob. Agents Chemother. 41 (1997) 2770-2772 [PubMed].
- Nikaido H., Multidrug efflux pumps of Gram-negative bacteria, J. Bacteriol. 178 (1996) 5853-5859 [PubMed].
- Nikaido H., Antibiotic resistance caused by Gram-negative multidrug efflux pumps, Clin. Infect. Dis. 27 Suppl. 1 (1998) S32-S41 [PubMed].
- Oethinger M., Podglajen I., Kern W.V., Levy S.B., Overexpression of the marA or soxS regulatory gene in clinical topoisomerase mutants of Escherichia coli, Antimicrob. Agents Chemother. 42 (1998) 2089-2094 [PubMed].
- Oethinger M., Kern W.V., Jellen-Ritter A.S., McMurry L.M., Levy S.B., Ineffectiveness of topoisomerase mutations in mediating clinically significant fluoroquinolone resistance in Escherichia coli in the absence of the AcrAB efflux pump, Antimicrob. Agents Chemother. 44 (2000) 10-13 [PubMed].
- Okusu H., Nikaido H., AcrAB efflux pump plays a major role in the antibiotic resistance phenotype of Escherichia coli multiple-antibiotic-resistance (Mar) mutants, J. Bacteriol. 178 (1996) 306-308 [PubMed].
- Ouabdesselam S., Tankovic J., Soussy C.J., Quinolone resistance mutations in the gyrA gene of clinical isolates of Salmonella, Microb. Drug Resist. 2 (1996) 299-302 [PubMed].
- Paulsen I.T., Brown M.H., Skurray R.A., Proton-dependent multidrug efflux systems, Microbiol. Rev. 60 (1996) 575-608 [PubMed].
- Piddock L.J.V., Griggs D.J., Hall M.C., Jin Y.F., Ciprofloxacin resistance in clinical isolates of Salmonella typhimurium obtained from two patients, Antimicrob. Agents Chemother. 37 (1993) 662-666 [PubMed].
- Piddock L.J.V., Ricci V., McLaren I., Griggs D.J., Role of mutation in the gyrA and parC genes of nalidixic-acid-resistant salmonella serotypes isolated from animals in the United Kingdom, J. Antimicrob. Chemother. 41 (1998) 635-641 [CrossRef] [PubMed].
- Piddock L.J.V., White D.G., Gensberg K., Pumbwe L., Griggs D.J., Evidence for an efflux pump mediating multiple antibiotic resistance in Salmonella enterica serovar Typhimurium, Antimicrob. Agents Chemother. 44 (2000) 3118-3121 [CrossRef] [PubMed].
- Pomposiello P.J., Demple B., Identification of SoxS-regulated genes in Salmonella enterica serovar Typhimurium, J. Bacteriol. 182 (2000) 23-29 [PubMed].
- Poole K., Efflux-mediated resistance to fluoroquinolones in Gram-negative bacteria, Antimicrob. Agents Chemother. 44 (2000) 2233-2241 [CrossRef] [PubMed].
- Putman M., van Veen H.W., Konings W.N., Molecular properties of bacterial multidrug transporters, Microbiol. Mol. Biol. Rev. 64 (2000) 672-693 [PubMed].
- Rajyaguru J.M., Muszynski M.J., Association of resistance to trimethoprim/sulphamethoxazole, chloramphenicol and quinolones with changes in major outer membrane proteins and lipopolysaccharide in Burkholderia cepacia, J. Antimicrob. Chemother. 40 (1997) 803-809 [CrossRef] [PubMed].
- Reyna F., Huesca M., Gonzalez V., Fuchs L.Y., Salmonella typhimurium gyrA mutations associated with fluoroquinolone resistance, Antimicrob. Agents Chemother. 39 (1995) 1621-1623 [PubMed].
- Ridley A., Threlfall E.J., Molecular epidemiology of antibiotic resistance genes in multiresistant epidemic Salmonella typhimurium DT 104, Microb. Drug Resist. 4 (1998) 113-118 [PubMed].
- Ruiz J., Castro D., Goni P., Santamaria J.A., Borrego J.J., Vila J., Analysis of the mechanism of quinolone resistance in nalidixic acid-resistant clinical isolates of Salmonella serotype Typhimurium, J. Med. Microbiol. 46 (1997) 623-628 [PubMed].
- Stone B.J., Miller V.L., Salmonella enteritidis has a homologue of tolC that is required for virulence in BALB/c mice, Mol. Microbiol. 17 (1995) 701-712 [PubMed].
- Sulavik M.C., Dazer M., Miller P.F., The Salmonella typhimurium mar locus: molecular and genetic analyses and assessment of its role in virulence, J. Bacteriol. 179 (1997) 1857-1866 [PubMed].
- Thanassi D.G., Cheng L.W., Nikaido H., Active efflux of bile salts by Escherichia coli, J. Bacteriol. 179 (1997) 2512-2518 [PubMed].
- Tsukagoshi N., Aono R., Entry into and release of solvents by Escherichia coli in an organic-aqueous two-liquid-phase system and substrate specificity of the AcrAB-TolC solvent-extruding pump, J. Bacteriol. 182 (2000) 4803-4810 [CrossRef] [PubMed].
- Walker R.A., Lawson A.J., Lindsay E.A., Ward L.R., Wright P.A., Bolton F.J., Wareing D.R.A., Corkish J.D., Davies R.H., Threlfall E.J., Decreased susceptibility to ciprofloxacin in outbreak-associated multiresistant Salmonella typhimurium DT104, Vet. Rec. 147 (2000) 395-396 [PubMed].
- White D.G., Goldman J.D., Demple B., Levy S.B., Role of the acrAB locus in organic solvent tolerance mediated by expression of marA, soxS, or robA in Escherichia coli, J. Bacteriol. 179 (1997) 6122-6126 [PubMed].
- Wiuff C., Madsen M., Baggesen D.L., Aarestrup F.M., Quinolone resistance among Salmonella enterica from cattle, broilers, and swine in Denmark, Microb. Drug Resist. 6 (2000) 11-17 [PubMed].
- Zgurskaya H.I., Nikaido H., Bypassing the periplasm: reconstitution of the AcrAB multidrug efflux pump of Escherichia coli, Proc. Natl. Acad. Sci. USA 96 (1999) 7190-7195 [CrossRef] [PubMed].
- Zgurskaya H.I., Nikaido H., AcrA is a highly asymmetric protein capable of spanning the periplasm, J. Mol. Biol. 285 (1999) 409-420 [CrossRef] [PubMed].
- Zgurskaya H.I., Nikaido H., Cross-linked complex between oligomeric periplasmic lipoprotein AcrA and the inner-membrane-associated multidrug efflux pump AcrB from Escherichia coli, J. Bacteriol. 182 (2000) 4264-4267 [CrossRef] [PubMed].
- Zgurskaya H.I., Nikaido H., Multidrug resistance mechanisms: drug efflux across two membranes, Mol. Microbiol. 37 (2000) 219-225 [PubMed].