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All issues Volume 41 / No 4 (July–August 2010) Vet. Res., 41 4 (2010) 52 Full HTML
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Table IV.

Assessment of Neospora caninum vertical transmission by parasite PCR-detection in neonatal brains.

N. caninum infected mice group (and control group) Litter transmission (% litters with at least one PCR-positive pup) Parasite detection rate in dead neonates (% PCR-positive neonates that succumbed to infection from day 2 PP) Parasite detection rate in alive neonates (% PCR-positive neonates that overcame infection at day 30 PP) Vertical transmission rate (%)*
Nc-Spain 2H 90.9 7/7 (100)a 20/37 (54)c 27/44 (61.3)f,1,2
Nc-Spain 3H 100 2/2 (100) 63/71 (88.7) 65/73 (89)3
Nc-Spain 4H 100 37/38 (97.3) –d 37/38 (97.3)3
Nc-Spain 5H 100 39/39 (100) 3/3 (100) 42/42 (100)3
Nc-Spain 6 91.6 12/13 (92.3) 18/39 (46.1) 30/52 (57.6)1
Nc-Spain 7 91.6 17/21 (80.9) 2/3 (66.6) 19/24 (79.1)
Nc-Spain 8 94.7 –b 48/85 (56.4) 48/85 (56.4)1,2
Nc-Spain 9 100 11/12 (91.6) 9/26 (34.6) 20/38 (52.6)1
Nc-Spain 10 100 7/7 (100) 33/54 (61.1) 40/61 (65.5)
Nc-Liverpool 100 22/23 (95.6) –d 22/23 (95.6)2,3
Control 0 –b 0/30 (0)e 0/30 (0)e

* Vertical transmission determined by parasite detection in brains from all neonates.

a,c,f

Number of infected neonates/number of neonates that succumbed to infection, number of neonates that overcame the infection at day 30 PP, and number of total animals analysed, according to superscript.

b

No neonates succumbed to infection or brain samples were not collected due to cannibalism by the dams.

d

All neonates succumbed to infection.

e

Brain samples from 10 female mice and their offspring were selected as the control.

1,2,3

Percentages determined for infected groups followed by unlike superscripts differ significantly by χ2 multiple-comparison test.