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Table II.
Serological analysis of sera from swine inoculated with rS. cho.
| Group | Animal no. | Neutralizing antibodya |
Mean % inhibition of antibody against 3ABCb ± SD |
||||
|---|---|---|---|---|---|---|---|
| Day 0 | Day 7 | Day 14 | Day 0 | Day 7 | Day 14 | ||
| Saline | 28-8 | ≤ 3 | 108 | 362 | NDc | ND | ND |
| 1-48 | ≤ 3 | 362 | 362 | ND | ND | ND | |
| 3-2 | ≤ 3 | 128 | 362 | 2.6 ± 0.2 | 39.5 ± 0.1 | 36.2 ± 2.0 | |
| S. cho | 6-4 | ≤ 3 | 362 | 362 | 12.9 ± 2.9 | 42.9 ± 1.1 | 55.9 ± 1.1 |
| 4-6 | ≤ 3 | 180 | 362 | 13.6 ± 1.9 | 54.5 ± 1.9 | 63.2 ± 0.7 | |
| pLacZ/S. cho | 6-2 | ≤ 3 | 180 | 362 | ND | ND | ND |
| 43-14 | ≤ 3 | 180 | 362 | ND | ND | ND | |
| 43-5 | ≤ 3 | 256 | 256 | ND | ND | ND | |
| 49-3 | ≤ 3 | 128 | 180 | ND | ND | ND | |
| p3D-NT56/S. cho | 2-7 | ≤ 3 | 23 | 180 | 12.16 ± 1.1 | 12.6 ± 2.4 | 25.8 ± 0.4 |
| 5-6 | ≤ 3 | 12 | 180 | 6.5 ± 1.0 | 10.1 ± 0.3 | 27.8 ± 4.2 | |
| 3-3 | ≤ 3 | 12 | 180 | 12.8 ± 0.8 | 9.5 ± 0.2 | 32.9 ± 5.2 | |
| 1-1 | ≤ 3 | 23 | 180 | 11.9 ± 0.5 | 21.2 ± 3.8 | 29.5 ± 2.7 | |
| p3D-NT56/S. cho d | 1-3 | ≤ 3 | 108 | 128 | 3.1 ± 1.0 | 36.5 ± 1.2 | 50.0 ± 4.3 |
| 7-1 | ≤ 3 | 23 | 180 | 6.4 ± 0.0 | 27.9 ± 0.2 | 33.6 ± 3.2 | |
| 3-4 | ≤ 3 | 108 | 180 | 7.4 ± 0.7 | 39.1 ± 1.8 | 45.5 ± 0.2 | |
| 1-34 | ≤ 3 | 64 | 180 | ND | ND | ND | |