Open Access

Table II.

E. coli regulated pbMEC genes, ranked according to the extent of changes in the mRNA concentration.

Gene Symbol Description Fold change
(A) Up-regulated (top-20 stimulated)
SAA3 serum amyloid A 3 1070.4
CCL5* chemokine (C-C motif) ligand 5 867.7
LAP lingual antimicrobial peptide 423.7
MX2 myxovirus (influenza virus) resistance 2 366.6
RSAD2 radical S-adenosyl methionine domain containing 2 311.9
CCL20 chemokine (C-C motif) ligand 20 311.3
IL8 interleukin 8 256.5
— Bt.17195.1.A1_ata 223.5
ISG12(A) similar to putative ISG12(a) protein 206.9
IFI44 interferon-induced protein 44 202.1
HP haptoglobin 152.9
IFI6 interferon, alpha-inducible protein 6 108.8
IFI44 interferon-induced protein 44 102.3
RTP4 receptor (chemosensory) transporter protein 4 97.9
IFI44 interferon-induced protein 44 96.0
PLAC8 placenta-specific 8 95.0
IL1B interleukin 1, beta 76.6
IFI44 Interferon-induced protein 44 71.7
MRM1 mitochondrial rRNA methyltransferase 1 homolog 65.3
CCL2 chemokine (C-C motif) ligand 2 63.6
 
(B) Down-regulated (20 most-down regulated)
ACSM1 acyl-CoA synthetase medium-chain family member 1 −5.2
RASL12 RAS-like, family 12 −5.0
MATN2 matrilin 2 −3.6
— Bt.24328.1.S1_at −3.4
FMOD fibromodulin −3.3
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) −3.2
— Bt.20861.1.A1_at −3.0
— Bt.14122.1.A1_at −2.9
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) −2.7
APOD apolipoprotein D −2.6
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 −2.5
GYPC glycophorin C (Gerbich blood group) −2.5
LOC788422 hypothetical protein LOC788422 −2.5
CITED1 Cbp/p300-interacting transactivator −2.4
TMEM117 transmembrane protein 117 −2.4
— Bt.12819.1.S1_at −2.4
ZCCHC7 zinc finger, CCHC domain containing 7 −2.4
PDK4 pyruvate dehydrogenase kinase, isozyme 4 −2.3
SELENBP1 selenium binding protein 1 −2.3
MED11 mediator complex subunit 11 −2.3
*

Underlined, IPA category Inflammatory Response.

a

Non annotated probe sets are specified by the respective Affymetrix identifier.