Rapid and widely disseminated acute phase protein response after experimental bacterial infection of pigs | Veterinary Research, a journal on Animal Infection

Open Access

Table III.

Individual variation in lung lesion score, serum IL-6 concentration (dpi −1 and 1), IL-6 mRNA level in leukocytes relative to mean of control group (dpi 1 only) and re-isolation of inoculum strain of A. pleuropneumoniae.

Pig No.^a	Lung lesion score^b	IL-6 protein (pg/mL)		IL-6 mRNA (relative conc.) 1 dpi	Re-isolation^c
		−1 dpi	1 dpi	IL-6 mRNA (relative conc.) 1 dpi
23	0	–	–	0.653	–
24	0	–	–	0.722	–
25	4	–	–	0.801	ton.
26	3	–	391	1.080	lu., ton.
27	3	392	810	2.522	lu., ton.
28	3	–	1429	3.316	lu., ton., li.
29	0	–	–	0.743	ton.
30	4	–	6114	25.906	lu., ton., li., spl.
31	4	–	2097	4.520	lu., ton., li., spl.
32	3	–	1628	1.180	lu., ton., li., spl.
33	3	–	461	1.694	lu., ton.
34	4	–	739	7.707	lu., ton., li., spl.
35	0	–	–	0.858	ton.
36	4	–	4614	25.841	lu., ton., li., spl.

Control animals: 23 and 24, inoculated animals: 25–36.

Lung lesion scores: 0: no lesions, 1: 1–2 lesions, < 15 mm diameter, 2:1–2 lesions (each < 50 mm diam.) or a few scattered petechiae, 3: More than 2 lesions (each < 50 mm diam.) or numerous scattered petechiae, 4: More severe than 3.

Re-isolation: lu.: lung, li.: liver, spl.: spleen, ton.: tonsil.