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Table II.
Extrahepatic and hepatic expression of APP and IL-6 ± standard error of the mean. The mean value of the 10 infected animals is shown relative to the 5 control animals as described in Materials and methods.
| Gene | Tissue |
||||
|---|---|---|---|---|---|
| Liver | Leukocytes | Spleen | Lymph | Tonsil | |
| AGP | 0.46 ± 0.04** | E (3/5 10/10)a | E (1/5 5/10) | E (2/5 2/10) | Not expressed |
| ALB | 0.16 ± 0.02*** | E (5/5 9/10) | E (5/5 1/10) | E (1/5 1/10) | 0.75 ± 0.08 |
| APOA1 | 0.53 ± 0.08* | 0.53 ± 0.23 | 0.74 ± 0.09* | 2.03 ± 1.26 | 1.16 ± 0.46 |
| CRP | 2.10 ± 0.41* | 4.88 ± 1.72** | E (3/5 5/10) | 3.70 ± 0.81*** | E (2/5 5/10) |
| FIB | 3.02 ± 0.21*** | Not expressed | 4.12 ± 1.11*** | E (4/5 9/10) | Not expressed |
| Hp | 1.92 ± 0.23** | 23.23 ± 5.24*** | 21.55 ± 4.93*** | 3.42 ± 0.81** | 0.94 ± 0.41 |
| PigMAP | 7.47 ± 0.48*** | E (5/5 10/10)b | 4.36 ± 0.62*** | 5.43 ± 1.72* | 2.27 ± 0.55** |
| SAA2 | 68.19 ± 12.90*** | 95.66 ± 21.30*** | 24.52 ± 9.70*** | 668 ± 160** | 2.11 ± 0.28* |
| TF | 0.17 ± 0.02*** | 0.45 ± 0.12 | 0.37 ± 0.05** | 1.30 ± 0.26 | 1.32 ± 0.27 |
| TTR | 0.04 ± 0.0*** | E (1/5 1/10) | 0.39 ± 0.06 | 0.83 ± 0.18 | E (4/5 6/10) |
| IL-6 | 11.16 ± 8.30* | 7.46 ± 3.31* | 14.08 ± 7.49*** | 167 ± 130** | 4.37 ± 1.81* |