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Evaluation of the immune responses against reduced doses of Brucella abortus S19 (calfhood) vaccine in water buffaloes (Bubalus bubalis), India

Rajeswari Shome, Sreenivasulu Kilari, Amol Sahare, et al.
Vaccine 38 (45) 7070 (2020)
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Protection of mice from Brucella infection by immunization with attenuated Salmonellaenterica serovar typhimurium expressing A L7/L12 and BLS fusion antigen of Brucella

Zhongpeng Zhao, Min Li, Deyan Luo, et al.
Vaccine 27 (38) 5214 (2009)
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Whole-genome sequencing of rough Brucella melitensis in China provides insights into its genetic features

Xiaowen Yang, Dongri Piao, Lingling Mao, et al.
Emerging Microbes & Infections 9 (1) 2147 (2020)
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Control and Eradication of Brucella melitensis Infection in Sheep and Goats

José M. Blasco and Baldomero Molina-Flores
Veterinary Clinics of North America: Food Animal Practice 27 (1) 95 (2011)
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Brucella abortus Δ rpoE1 confers protective immunity against wild type challenge in a mouse model of brucellosis

Jonathan W. Willett, Julien Herrou, Daniel M. Czyż, Jason X. Cheng and Sean Crosson
Vaccine 34 (42) 5073 (2016)
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Antibiotic Resistance in the Food Chain: A Developing Country-Perspective

Luria Leslie Founou, Raspail Carrel Founou and Sabiha Yusuf Essack
Frontiers in Microbiology 7 (2016)
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Immune Response to Mucosal Brucella Infection

Rubén López-Santiago, Ana Beatriz Sánchez-Argáez, Liliana Gabriela De Alba-Núñez, Shantal Lizbeth Baltierra-Uribe and Martha Cecilia Moreno-Lafont
Frontiers in Immunology 10 (2019)
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Molecular typing of isolates obtained from aborted foetuses in Brucella -free Holstein dairy cattle herd after immunisation with Brucella abortus RB51 vaccine in Egypt

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Acta Tropica 164 267 (2016)
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A Combined DNA Vaccine Encoding BCSP31, SOD, and L7/L12 Confers High Protection Against Brucella abortus 2308 by Inducing Specific CTL Responses

Da-Hai Yu, Xi-Dan Hu, Hong Cai and Min Li
DNA and Cell Biology 26 (6) 435 (2007)
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A Combined DNA Vaccine Provides Protective Immunity Against Mycobacterium bovis and Brucella abortus in Cattle

Xi-Dan Hu, Da-Hai Yu, Su-Ting Chen, Shu-Xia Li and Hong Cai
DNA and Cell Biology 28 (4) 191 (2009)
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Protective Live Oral Brucellosis Vaccines Stimulate Th1 and Th17 Cell Responses

Beata Clapp, Jerod A. Skyberg, Xinghong Yang, et al.
Infection and Immunity 79 (10) 4165 (2011)
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Disruption of pyruvate phosphate dikinase in Brucella ovis PA CO2-dependent and independent strains generates attenuation in the mouse model

Nieves Vizcaíno, Lara Pérez-Etayo, Raquel Conde-Álvarez, Maite Iriarte, Ignacio Moriyón and Amaia Zúñiga-Ripa
Veterinary Research 51 (1) (2020)
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Efficacy of Brucella abortus S19 and RB51 vaccine strains: A systematic review and meta‐analysis

Marina Martins Oliveira, Carine Rodrigues Pereira, Izabela Regina Cardoso Oliveira, Jacques Godfroid, Andrey Pereira Lage and Elaine Maria Seles Dorneles
Transboundary and Emerging Diseases (2021)
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Evaluation of DNA vaccine encoding BCSP31 surface protein of Brucella abortus for protective immunity

Waqar Imtiaz, Ahrar Khan, Shafia Tehseen Gul, et al.
Microbial Pathogenesis 125 514 (2018)
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Genomics and Biotechnological Advances in Veterinary, Poultry, and Fisheries

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The CO2-dependence of Brucella ovis and Brucella abortus biovars is caused by defective carbonic anhydrases

Lara Pérez-Etayo, María Jesús de Miguel, Raquel Conde-Álvarez, et al.
Veterinary Research 49 (1) (2018)
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Brucella melitensis M5-90Δbp26 as a potential live vaccine that allows for the distinction between natural infection and immunization

Tiansen Li, Zhixia Tong, Meiling Huang, et al.
Canadian Journal of Microbiology 63 (8) 719 (2017)
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Vaccination with Brucella recombinant DnaK and SurA proteins induces protection against Brucella abortus infection in BALB/c mice

Maria Victoria Delpino, Silvia Marcela Estein, Carlos Alberto Fossati, Pablo César Baldi and Juliana Cassataro
Vaccine 25 (37-38) 6721 (2007)
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Meta-Analysis and Advancement of Brucellosis Vaccinology

Tatiane F. Carvalho, João Paulo A. Haddad, Tatiane A. Paixão, Renato L. Santos and Roy Martin Roop
PLOS ONE 11 (11) e0166582 (2016)
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Isolation of Brucella melitensis from a RB51-vaccinated seronegative goat

Enrique Herrera, Aldo Rivera, E. Gabriela Palomares, Rigoberto Hernández-Castro and Efrén Díaz-Aparicio
Tropical Animal Health and Production 43 (6) 1069 (2011)
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Zoonotic tuberculosis and brucellosis in Africa: neglected zoonoses or minor public-health issues? The outcomes of a multi-disciplinary workshop

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Rough brucella strain RM57 is attenuated and confers protection against Brucella melitensis

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Confronting the barriers to develop novel vaccines against brucellosis

Sérgio Costa Oliveira, Guillermo Hernán Giambartolomei and Juliana Cassataro
Expert Review of Vaccines 10 (9) 1291 (2011)
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Brucellosis in Sub-Saharan Africa: Current challenges for management, diagnosis and control

M. Ducrotoy, W.J. Bertu, G. Matope, et al.
Acta Tropica 165 179 (2017)
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Occupational infection due to Brucella abortus S19 among workers involved in vaccine production in Argentina

J.C. Wallach, M.C. Ferrero, M. Victoria Delpino, C.A. Fossati and P.C. Baldi
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Importance of Lipopolysaccharide and Cyclicβ-1,2-Glucans inBrucella-Mammalian Infections

Andreas F. Haag, Kamila K. Myka, Markus F. F. Arnold, Paola Caro-Hernández and Gail P. Ferguson
International Journal of Microbiology 2010 1 (2010)
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A Brucella melitensis M5-90 wboA deletion strain is attenuated and enhances vaccine efficacy

Zhi-Qiang Li, Jing-Xue Shi, Wen-Dong Fu, et al.
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Effect of polymorphisms in the Slc11a1 coding region on resistance to brucellosis by macrophages in vitro and after challenge in two Bos breeds (Blanco Orejinegro and Zebu)

Rodrigo Martínez, Susana Dunner, Rubén Toro, et al.
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Cloning, expression and immunogenicity of the translation initiation factor 3 homologue of Brucella abortus

Marcela González, Edilia Andrews, Hugo Folch, et al.
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Design and influence of γ-irradiation on the biopharmaceutical properties of nanoparticles containing an antigenic complex from Brucella ovis

Raquel Da Costa Martins, Carlos Gamazo and Juan Manuel Irache
European Journal of Pharmaceutical Sciences 37 (5) 563 (2009)
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Serological profile of buffalo (Bubalus bubalis) female calves vaccinated with standard Brucella abortus strain 19 vaccine using rose bengal, 2-mercaptoethanol and complement fixation tests

G. Nardi Júnior, M.G. Ribeiro, A.M. Jorge, J. Megid and L.M.P. Silva
Biologicals 40 (2) 158 (2012)
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ΔznuAΔpurE Brucella abortus 2308 mutant as a live vaccine candidate

Xinghong Yang, Theresa Thornburg, Nancy Walters and David W. Pascual
Vaccine 28 (4) 1069 (2010)
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Study of Brucellosis Incidence in a Bovine Dairy Farm Infected with Brucella abortus, Where Cattle Was Revaccinated with RB51

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A “One Health” surveillance and control of brucellosis in developing countries: Moving away from improvisation

Jacques Godfroid, Sascha Al Dahouk, Georgios Pappas, et al.
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An IL-15 adjuvant enhances the efficacy of a combined DNA vaccine against Brucella by increasing the CD8+ cytotoxic T cell response

Xi-Dan Hu, Su-Ting Chen, Jia-Yun Li, et al.
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Existing and future vaccines against brucellosis in small ruminants

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Identification of Brucella melitensis 16M genes required for bacterial survival in the caprine host

Michel S. Zygmunt, Sue D. Hagius, Joel V. Walker and Philip H. Elzer
Microbes and Infection 8 (14-15) 2849 (2006)
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Brucella abortus 2308ΔNodVΔNodW double-mutant is highly attenuated and confers protection against wild-type challenge in BALB/c mice

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Brucella abortus: Current Research and Future Trends

Tariq Jamil, Falk Melzer, John Njeru, et al.
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Biodefense Research Methodology and Animal Models, Second Edition

Bret Purcell and Robert Rivard
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Isolation of a field strain of Brucella abortus from RB51-vaccinated- and brucellosis-seronegative bovine yearlings that calved normally

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Mechanism of Asp24 Upregulation in Brucella abortus Rough Mutant with a Disrupted O-Antigen Export System and Effect of Asp24 in Bacterial Intracellular Survival

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Genome Sequences of Three Live Attenuated Vaccine Strains of Brucella Species and Implications for Pathogenesis and Differential Diagnosis

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Journal of Bacteriology 194 (21) 6012 (2012)
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In Vivo Differences in the Virulence, Pathogenicity, and Induced Protective Immunity of wboA Mutants from Genetically Different Parent Brucella spp

Zhen Wang, Jianrui Niu, Shuangshan Wang, Yanli Lv and Qingmin Wu
Clinical and Vaccine Immunology 20 (2) 174 (2013)
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Protective and therapeutic efficacy study of divalent fusion protein rL7/L12-Omp25 against B. abortus 544 in presence of IFNγ

Soumya Paul, Bhavani V. Peddayelachagiri, Sowmya Nagaraj, Balakrishna Konduru and Harsh V. Batra
Applied Microbiology and Biotechnology 102 (20) 8895 (2018)
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Rev1 wbdR tagged vaccines against Brucella ovis

Beatriz Aragón-Aranda, María Jesús de Miguel, Estrella Martínez-Gómez, et al.
Veterinary Research 50 (1) (2019)
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Novel Solutions for Vaccines and Diagnostics To Combat Brucellosis

Satadru Sekhar Mandal, Lucy Duncombe, N. Vijaya Ganesh, Susmita Sarkar, Laurence Howells, Philip J. Hogarth, David R. Bundle and John McGiven
ACS Central Science 3 (3) 224 (2017)
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Rough Brucella neotomae provides protection against Brucella suis challenge in mice

Neeta Jain-Gupta, Steven G. Waldrop, Nancy M. Tenpenny, et al.
Veterinary Microbiology 239 108447 (2019)
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Vaccine development targeting lipopolysaccharide structure modification

Yun Zhao, Vilma Arce-Gorvel, Raquel Conde-Álvarez, Ignacio Moriyon and Jean-Pierre Gorvel
Microbes and Infection 20 (9-10) 455 (2018)
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Extensive rearing hinders Maedi-Visna Virus (MVV) infection in sheep

Iratxe Leginagoikoa, Ramón A. Juste, Jesse Barandika, et al.
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Mucosal Vaccines

David W. Pascual
Mucosal Vaccines 445 (2020)
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Genome Mapping and Genomics in Animal-Associated Microbes

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GFP tagging of Brucella melitensis Rev1 allows the identification of vaccinated sheep

Ana Zabalza‐Baranguá, Beatriz San‐Román, Carlos Chacón‐Díaz, et al.
Transboundary and Emerging Diseases 66 (1) 505 (2019)
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Restriction site polymorphisms in the genes encoding new members of group 3 outer membrane protein family ofBrucellaspp.

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Molecular characterization and differential expression analysis of interleukin 1β from Ovis aries

Yi-Ming Shui, Shi-Ying Lu, Xing Guo, et al.
Microbial Pathogenesis 116 180 (2018)
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Individual heterogeneity in erythrocyte susceptibility toBabesia divergensis a critical factor for the outcome of experimental spleen-intact sheep infections

Laurence Malandrin, Maggy Jouglin, Emmanuelle Moreau and Alain Chauvin
Veterinary Research 40 (4) 25 (2009)
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Brucellosis: Improved Diagnostics and Vaccine Insights from Synthetic Glycans

David R. Bundle and John McGiven
Accounts of Chemical Research 50 (12) 2958 (2017)
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A combined vaccine against Brucella abortus and infectious bovine rhinotracheitis

Govindasamy Kamaraj, Shankar R. Chinchkar, Lingala Rajendra and Villuppanoor Alwar Srinivasan
Indian Journal of Microbiology 49 (2) 161 (2009)
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Brucellosis - new aspects of an old disease

S.J. Cutler, A.M. Whatmore and N.J. Commander
Journal of Applied Microbiology 98 (6) 1270 (2005)
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Milk Production Increase in a Dairy Farm under a Six-Year Brucellosis Control Program

Enrique Herrera, Gabriela Palomares and Efrén Díaz-Aparicio
Annals of the New York Academy of Sciences 1149 (1) 296 (2008)
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Efficacy of strain RB51 vaccine in protecting infection and vertical transmission against Brucella abortus in Sprague-Dawley rats

Md. Ariful Islam, Mst. Minara Khatun, Byeong-Kirl Baek and Sung-Il Lee
Journal of Veterinary Science 10 (3) 211 (2009)
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Mucosal immunization with polymeric antigen BLSOmp31 using alternative delivery systems against Brucella ovis in rams

Alejandra Graciela Díaz, Daniela Alejandra Quinteros, Fernando Alberto Paolicchi, et al.
Veterinary Immunology and Immunopathology 209 70 (2019)
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Bacteriological and molecular investigation of B. melitensis in dairy cows in Iran

Hassan Sharifiyazdi, Masoud Haghkhah, Ali Mohammad Behroozikhah and Ebrahim Nematgorgani
Comparative Clinical Pathology 21 (3) 269 (2012)
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Lethality of Brucella microti in a murine model of infection depends on the wbkE gene involved in O-polysaccharide synthesis

Safia Ouahrani-Bettache, María P. Jiménez De Bagüés, Jorge De La Garza, et al.
Virulence 10 (1) 868 (2019)
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Bovine brucellosis – a comprehensive review

Sandip Kumar Khurana, Anju Sehrawat, Ruchi Tiwari, et al.
Veterinary Quarterly 41 (1) 61 (2021)
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Genomic Analysis of Natural Rough Brucella melitensis Rev.1 Vaccine Strains: Identification and Characterization of Mutations in Key Genes Associated with Bacterial LPS Biosynthesis and Virulence

David Kornspan, Regina Lubkovskaia, Shubham Mathur, Adva Yeheskel and Mali Salmon-Divon
International Journal of Molecular Sciences 21 (24) 9341 (2020)
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A combined subunit vaccine comprising BP26, Omp25 and L7/L12 against brucellosis

Sonal Gupta, Damini Singh, Manish Gupta and Rakesh Bhatnagar
Pathogens and Disease 77 (8) (2019)
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Brucella melitensis B115-based ELISA to unravel false positive serologic reactions in bovine brucellosis: a field study

Adriana Trotta, Mariarosaria Marinaro, Margie Cirilli, et al.
BMC Veterinary Research 16 (1) (2020)
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What have we learned from brucellosis in the mouse model?

María-Jesús Grilló, José María Blasco, Jean Pierre Gorvel, Ignacio Moriyón and Edgardo Moreno
Veterinary Research 43 (1) (2012)
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Mutants in the lipopolysaccharide of Brucella ovis are attenuated and protect against B. ovis infection in mice

Pedro Soler-Lloréns, Yolanda Gil-Ramírez, Ana Zabalza-Baranguá, Maite Iriarte, Raquel Conde-Álvarez, Amaia Zúñiga-Ripa, Beatriz San Román, Michel S Zygmunt, Nieves Vizcaíno, Axel Cloeckaert, María-Jesús Grilló, Ignacio Moriyón and Ignacio López-Goñi
Veterinary Research 45 (1) (2014)
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Immunoproteomic identification of immunodominant antigens independent of the time of infection in Brucella abortus 2308-challenged cattle

Jin Ju Lee, Hannah Leah Simborio, Alisha Wehdnesday Bernardo Reyes, Dae Geun Kim, Huynh Tan Hop, Wongi Min, Moon Her, Suk Chan Jung, Han Sang Yoo and Suk Kim
Veterinary Research 46 (1) (2015)
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Evaluation of Duration of Immunogenicity and Protective Efficacy of Improved Influenza Viral Vector–Based Brucella abortus Vaccine Against Brucella melitensis Infection in Sheep and Goats

Aigerim Mailybayeva, Sholpan Ryskeldinova, Nadezhda Zinina, et al.
Frontiers in Veterinary Science 7 (2020)
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Deletion of the GI-2 integrase and the wbkA flanking transposase improves the stability of Brucella melitensis Rev 1 vaccine

Marcos Mancilla, María-Jesús Grilló, María-Jesús de Miguel, Ignacio López-Goñi, Beatriz San-Román, Ana Zabalza-Baranguá and Ignacio Moriyón
Veterinary Research 44 (1) (2013)
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Simultaneous Immunization with Omp25 and L7/L12 Provides Protection against Brucellosis in Mice

Sonal Gupta, Surender Mohan, Vikas Kumar Somani, Somya Aggarwal and Rakesh Bhatnagar
Pathogens 9 (2) 152 (2020)
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A. A. Maruf, F. Yasmin, F. Yeasmin, et al.
Journal of Veterinary Medical and One Health Research 1 (2) 247 (2019)
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Characterization of a Novel Interleukin-1 Receptor Antagonist from Sheep (Ovis aries)

Shi-Jun Zhang, Xing Guo, Pan Hu, et al.
Journal of Interferon & Cytokine Research 40 (5) 268 (2020)
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Protective Properties of Rifampin-Resistant Rough Mutants of Brucella melitensis

R. Adone, F. Ciuchini, C. Marianelli, et al.
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MyD88, but Not Toll-Like Receptors 4 and 2, Is Required for Efficient Clearance of Brucella abortus

David S. Weiss, Kiyoshi Takeda, Shizuo Akira, Arturo Zychlinsky and Edgardo Moreno
Infection and Immunity 73 (8) 5137 (2005)
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Vaccination with the Recombinant Brucella Outer Membrane Protein 31 or a Derived 27-Amino-Acid Synthetic Peptide Elicits a CD4 + T Helper 1 Response That Protects against Brucella melitensis Infection

Juliana Cassataro, Silvia M. Estein, Karina A. Pasquevich, et al.
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Attenuated Bioluminescent Brucella melitensis Mutants GR019 ( virB4 ), GR024 ( galE ), and GR026 (BMEI1090-BMEI1091) Confer Protection in Mice

Gireesh Rajashekara, David A. Glover, Menachem Banai, David O'Callaghan and Gary A. Splitter
Infection and Immunity 74 (5) 2925 (2006)
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Evaluation of Protection Afforded by Brucella abortus and Brucella melitensis Unmarked Deletion Mutants Exhibiting Different Rates of Clearance in BALB/c Mice

M. M. Kahl-McDonagh and T. A. Ficht
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Interaction of Brucella suis and Brucella abortus Rough Strains with Human Dendritic Cells

Elisabeth Billard, Jacques Dornand and Antoine Gross
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Pilar María Muñoz, José-María Blasco and Bruno Garin-Bastuji
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Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): infection with Brucella abortus, B. melitensis and B. suis

Simon More, Anette Bøtner, Andrew Butterworth, Paolo Calistri, Klaus Depner, Sandra Edwards, Bruno Garin‐Bastuji, Margaret Good, Christian Gortázar Schmidt, Virginie Michel, Miguel Angel Miranda, Søren Saxmose Nielsen, Mohan Raj, Liisa Sihvonen, Hans Spoolder, Jan Arend Stegeman, Hans‐Hermann Thulke, Antonio Velarde, Preben Willeberg, Christoph Winckler, Francesca Baldinelli, Alessandro Broglia, Frank Verdonck, Beatriz Beltrán Beck, Lisa Kohnle, Joana Morgado and Dominique Bicout
EFSA Journal 15 (7) (2017)
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Nanotherapeutic provides dose sparing and improved antimicrobial activity against Brucella melitensis infections

Paul Lueth, Shannon L. Haughney, Andrea M. Binnebose, et al.
Journal of Controlled Release 294 288 (2019)
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Genomic Island 2 Is an Unstable Genetic Element Contributing to Brucella Lipopolysaccharide Spontaneous Smooth-to-Rough Dissociation

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Bartonella Species as a Potential Cause of Epistaxis in Dogs

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Discordant Brucella melitensis Antigens Yield Cognate CD8 + T Cells In Vivo

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Protective Immunity Elicited by a Divalent DNA Vaccine Encoding Both the L7/L12 and Omp16 Genes of Brucella abortus in BALB/c Mice

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A DNA Vaccine Coding for the Brucella Outer Membrane Protein 31 Confers Protection against B. melitensis and B. ovis Infection by Eliciting a Specific Cytotoxic Response

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Spontaneous Excision of the O-Polysaccharide wbkA Glycosyltranferase Gene Is a Cause of Dissociation of Smooth to Rough Brucella Colonies

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