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Defining correlates of protection for mammalian livestock vaccines against high-priority viral diseases
Samantha K. Davis, Fan Jia, Quentin G. Wright, Md. Tanjir Islam, Andrew Bean, Daniel Layton, David T. Williams and Stacey E. Lynch Frontiers in Immunology 15 (2024) https://doi.org/10.3389/fimmu.2024.1397780
Characterization of in vitro viral neutralization targets of highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) in alveolar macrophage and evaluation of protection potential against HP-PRRSV challenged based on combination of HP-PRRSV-structure proteins in vitro
Genomic similarity and antibody-dependent enhancement of immune serum potentially affect the protective efficacy of commercial MLV vaccines against NADC30-like PRRSV
Evaluation of dynamics of immune responses and protective efficacy in piglets immunized with an inactivated porcine reproductive and respiratory syndrome vaccine candidate
A potent CD8 T-cell response may be associated with partial cross-protection conferred by an attenuated Chinese HP-PRRSV vaccine against NADC30-like PRRSV challenge
UV-C irradiation as an effective tool for sterilization of porcine chimeric VP1-PCV2bCap recombinant vaccine
Alena Vrablikova, Martina Fojtikova, Renata Hezova, Pavlina Simeckova, Veronika Brezani, Nicol Strakova, Martin Fraiberk, Jan Kotoucek, Josef Masek and Ivan Psikal Scientific Reports 13(1) (2023) https://doi.org/10.1038/s41598-023-46791-9
Development of a Chimeric Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)-2 Vaccine Candidate Expressing Hypo-Glycosylated Glycoprotein-5 Ectodomain of Korean Lineage-1 Strain
Hwi-Yeon Choi, Min-Sik Kim, Yeong-Lim Kang, Jong-Chul Choi, In-Yeong Choi, Sung-Won Jung, Ji-Yun Jeong, Min-Chul Kim, Seong-Soo Hwang, Sang-Won Lee, Seung-Yong Park, Chang-Seon Song, In-Soo Choi and Joong-Bok Lee Veterinary Sciences 9(4) 165 (2022) https://doi.org/10.3390/vetsci9040165
Occurrence and Associated Risk Factors of Porcine Reproductive and Respiratory Syndrome Virus and Porcine Circovirus Type 2 Infections in Greece
Vasileios G. Papatsiros, Georgios Papakonstantinou, Eletherios Meletis, et al. Viral Immunology 35(3) 200 (2022) https://doi.org/10.1089/vim.2021.0124
Heterologous Challenge with PRRSV-1 MLV in Pregnant Vaccinated Gilts: Potential Risk on Health and Immunity of Piglets
Georgios Papakonstantinou, Eleftherios Meletis, Georgios Christodoulopoulos, Eleni D. Tzika, Polychronis Kostoulas and Vasileios G. Papatsiros Animals 12(4) 450 (2022) https://doi.org/10.3390/ani12040450
Tylvalosin Tartrate Improves the Health Status of Swine Herds during Immunization with Porcine Reproductive and Respiratory Syndrome Virus-Inactivated Vaccine
A porcine reproductive and respiratory syndrome virus (PRRSV)-specific IgM as a novel adjuvant for an inactivated PRRSV vaccine improves protection efficiency and enhances cell-mediated immunity against heterologous PRRSV challenge
Intranasal delivery of inactivated PRRSV loaded cationic nanoparticles coupled with enterotoxin subunit B induces PRRSV-specific immune responses in pigs
Two immune-based methods using immortalized porcine kidney macrophages for quantifying neutralizing activity against porcine reproductive and respiratory syndrome virus-2
Evaluation of the Cross-Protective Efficacy of a Chimeric PRRSV Vaccine against Two Genetically Diverse PRRSV2 Field Strains in a Reproductive Model
Chang-Gi Jeong, Amina Khatun, Salik Nazki, Seung-Chai Kim, Yun-Hee Noh, Sang-Chul Kang, Dong-Uk Lee, Myeon-Sik Yang, Nadeem Shabir, In-Joong Yoon, Bumseok Kim and Won-Il Kim Vaccines 9(11) 1258 (2021) https://doi.org/10.3390/vaccines9111258
The Ability of Porcine Reproductive and Respiratory Syndrome Virus Isolates to Induce Broadly Reactive Neutralizing Antibodies Correlates With In Vivo Protection
Francisco Javier Martínez-Lobo, Francisco Díez-Fuertes, Isabel Simarro, José M. Castro and Cinta Prieto Frontiers in Immunology 12 (2021) https://doi.org/10.3389/fimmu.2021.691145
Validation of a binary ethylenimine (BEI) inactivation procedure for biosafety treatment of foot-and-mouth disease viruses (FMDV), vesicular stomatitis viruses (VSV), and swine vesicular disease virus (SVDV)
Correlation of Neutralizing Antibodies (NAbs) between Sows and Piglets and Evaluation of Protectability Associated with Maternally Derived NAbs in Pigs against Circulating Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) under Field Conditions
Fu-Chun Hsueh, Sheng-Yuan Wang, Wei-Hao Lin, Chuen-Fu Lin, Chen-Yu Tsai, Chin-Wen Huang, Ning Sun, Ming-Tang Chiou and Chao-Nan Lin Vaccines 9(5) 414 (2021) https://doi.org/10.3390/vaccines9050414
Immune responses induced by inactivated porcine reproductive and respiratory syndrome virus (PRRSV) vaccine in neonatal pigs using different adjuvants
Sandra Vreman, Norbert Stockhofe-Zurwieden, Ditta J. Popma-de Graaf, et al. Veterinary Immunology and Immunopathology 232 110170 (2021) https://doi.org/10.1016/j.vetimm.2020.110170
Peptide Platform as a Powerful Tool in the Fight against COVID-19
Michela Murdocca, Gennaro Citro, Isabella Romeo, Antonio Lupia, Shane Miersch, Bruno Amadio, Alessia Bonomo, Antonio Rossi, Sachdev S. Sidhu, Pier Paolo Pandolfi, Stefano Alcaro, Federica Carla Sangiuolo and Giuseppe Novelli Viruses 13(8) 1667 (2021) https://doi.org/10.3390/v13081667
Adjuvants for swine vaccines: Mechanisms of actions and adjuvant effects
Interferon Inducing Porcine Reproductive and Respiratory Syndrome Virus Vaccine Candidate Protected Piglets from HP-PRRSV Challenge and Evoke a Higher Level of Neutralizing Antibodies Response
Yafei Li, Junhui Li, Sun He, Wei Zhang, Jian Cao, Xiaomei Pan, Huifen Tang, En-Min Zhou, Chunyan Wu and Yuchen Nan Vaccines 8(3) 490 (2020) https://doi.org/10.3390/vaccines8030490
Assessments of different inactivating reagents in formulating transmissible gastroenteritis virus vaccine
An inactivated enterovirus 71 vaccine is safe and immunogenic in healthy adults: A phase I, double blind, randomized, placebo-controlled, study of two dosages
A Triple Amino Acid Substitution at Position 88/94/95 in Glycoprotein GP2a of Type 1 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV1) Is Responsible for Adaptation to MARC-145 Cells
Jiexiong Xie, Ivan Trus, Dayoung Oh, Lise K. Kvisgaard, Julie C. F. Rappe, Nicolas Ruggli, Nathalie Vanderheijden, Lars E. Larsen, François Lefèvre and Hans J. Nauwynck Viruses 11(1) 36 (2019) https://doi.org/10.3390/v11010036
Vaccination with UV-inactivated nodavirus partly protects European sea bass against infection, while inducing few changes in immunity
Immunity raised by recent European subtype 1 PRRSV strains allows better replication of East European subtype 3 PRRSV strain Lena than that raised by an older strain
Attempts to enhance cross-protection against porcine reproductive and respiratory syndrome viruses using chimeric viruses containing structural genes from two antigenically distinct strains
Modified-live PRRSV subtype 1 vaccine UNISTRAIN® PRRS provides a partial clinical and virological protection upon challenge with East European subtype 3 PRRSV strain Lena
Inactivated porcine reproductive and respiratory syndrome virus vaccine adjuvanted with Montanide™ Gel 01 ST elicits virus-specific cross-protective inter-genotypic response in piglets
Efficacy of a combined inactivated porcine reproductive and respiratory syndrome virus vaccine using North American and European strains in specific pathogen free pigs
Protective humoral immune response induced by an inactivated porcine reproductive and respiratory syndrome virus expressing the hypo-glycosylated glycoprotein 5
Elevated dietary zinc oxide levels do not have a substantial effect on porcine reproductive and respiratory syndrome virus (PPRSV) vaccination and infection
Efficacy of an attenuated European subtype 1 porcine reproductive and respiratory syndrome virus (PRRSV) vaccine in pigs upon challenge with the East European subtype 3 PRRSV strain Lena
Comparison of Host Immune Responses to Homologous and Heterologous Type II Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Challenge in Vaccinated and Unvaccinated Pigs
Boosting In Planta Production of Antigens Derived from the Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) and Subsequent Evaluation of Their Immunogenicity
A novel baculovirus vector shows efficient gene delivery of modified porcine reproductive and respiratory syndrome virus antigens and elicits specific immune response
Development and Validation of an Assay To Detect Porcine Reproductive and Respiratory Syndrome Virus-Specific Neutralizing Antibody Titers in Pig Oral Fluid Samples
Kang Ouyang, Basavaraj Binjawadagi, Apisit Kittawornrat, et al. Clinical and Vaccine Immunology 20(8) 1305 (2013) https://doi.org/10.1128/CVI.00276-13
Antibody response and maternal immunity upon boosting PRRSV-immune sows with experimental farm-specific and commercial PRRSV vaccines
Mucosal vaccines to prevent porcine reproductive and respiratory syndrome: a new perspective
Gourapura J. Renukaradhya, Varun Dwivedi, Cordelia Manickam, Basavaraj Binjawadagi and David Benfield Animal Health Research Reviews 13(1) 21 (2012) https://doi.org/10.1017/S1466252312000023
Impact of a novel inactivated PRRS virus vaccine on virus replication and virus-induced pathology in fetal implantation sites and fetuses upon challenge
Inactivated virus vaccines from chemistry to prophylaxis: merits, risks and challenges
Iris Delrue, Dieter Verzele, Annemieke Madder and Hans J Nauwynck Expert Review of Vaccines 11(6) 695 (2012) https://doi.org/10.1586/erv.12.38
Comparison of the efficacy of autogenous inactivated Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) vaccines with that of commercial vaccines against homologous and heterologous challenges
Interaction of the European genotype porcine reproductive and respiratory syndrome virus (PRRSV) with sialoadhesin (CD169/Siglec-1) inhibits alveolar macrophage phagocytosis
Effect of the host cell line on the vaccine efficacy of an attenuated porcine reproductive and respiratory syndrome virus
Gabriela Calzada-Nova, Robert J. Husmann, William M. Schnitzlein and Federico A. Zuckermann Veterinary Immunology and Immunopathology 148(1-2) 116 (2012) https://doi.org/10.1016/j.vetimm.2012.05.008
Characterization of antigenic regions in the porcine reproductive and respiratory syndrome virus by the use of peptide-specific serum antibodies
A Variable Region in GP4 of European-Type Porcine Reproductive and Respiratory Syndrome Virus Induces Neutralizing Antibodies Against Homologous But Not Heterologous Virus Strains