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Comparative performance of tuberculin and defined-antigen cocktails for detecting bovine tuberculosis in BCG-vaccinated cattle in natural settings
Abebe Fromsa, Andrew J. K. Conlan, Sreenidhi Srinivasan, Balako Gumi, Wegene Bedada, Miserach Zeleke, Dawit Worku, Matios Lakew, Biniam Tadesse, Berecha Bayissa, Asegedech Sirak, Musse Girma Abdela, Getnet Abie Mekonnen, Tesfaye Chibssa, Maroudam Veerasami, Gareth J. Jones, H. Martin Vordermeier, Nick Juleff, James L. N. Wood, Gobena Ameni and Vivek Kapur Scientific Reports 15(1) (2025) https://doi.org/10.1038/s41598-025-85389-1
Enferplex bovine TB antibody test and bovine TB diagnosis: letter to the editor
Neil Watt, Alastair Hayton, Keith Cutler, Amanda O’Brien, John Clarke and Gordon D. Harkiss Veterinary Research Communications 48(1) 603 (2024) https://doi.org/10.1007/s11259-023-10229-4
Comparative Study of Mycobacterium bovis and Mycobacterium avium subsp. paratuberculosis In Vitro Infection in Bovine Bone Marrow Derived Macrophages: Preliminary Results
Benedetta Amato, Dorotea Ippolito, Maria Vitale, Rosa Alduina, Paola Galluzzo, Elisabetta Gerace, Flavia Pruiti Ciarello, Michele Fiasconaro, Vincenza Cannella and Vincenzo Di Marco Lo Presti Microorganisms 12(2) 407 (2024) https://doi.org/10.3390/microorganisms12020407
Abebe Fromsa, Andrew J.K. Conlan, Sreenidhi Sriniva, Balako Gumi, Wegene Bedada, Miserach Zeleke, Dawit Worku, Matios Lakew, Biniam Tadesse, Berecha Bayissa, Asegedech Sirak, Musse Girma Abdela, Getnet Abie Mekonnen, Tesfaye Chibssa, Maroudam Veerasami, Gareth Jones, H. Martin Vordermeier, Nick Juleff, James L.N. Wood, Gobena Ameni and Vivek Kapur (2024) https://doi.org/10.21203/rs.3.rs-4548496/v1
Assessing the feasibility of test-and-cull and test-and-segregation approaches for the control of high-prevalence bovine tuberculosis in Ethiopian intensive dairy farms
Assessing the impact of various tuberculin PPD brands on bovine tuberculosis diagnosis
Gustavo Echeverría, Martín J. Zumárraga, Freddy Proaño-Pérez, Francisco Barceló Blasco and Jacobus H. de Waard Scientific Reports 14(1) (2024) https://doi.org/10.1038/s41598-024-52089-1
The problem that residual Mycobacterium bovis infection poses for the eradication of bovine tuberculosis
Potential for improved detection of bovine tuberculosis by targeting combined blood biomarkers in multi-test algorithms
Archana A. Sridhara, Ashley Johnathan-Lee, Rubyat Elahi, Alina Sikar-Gang, Paul Lambotte, Javan Esfandiari, Lucia de Juan, Christian Gortazar, Breanne N. Marpe, Tyler C. Thacker, Mitchell V. Palmer, W. Ray Waters and Konstantin P. Lyashchenko Veterinary Immunology and Immunopathology 248 110419 (2022) https://doi.org/10.1016/j.vetimm.2022.110419
Can more information be extracted from bovine TB skin test outcomes to inform animal risk management? A retrospective observational animal-level study
Performance of Loop-Mediated Isothermal Amplification Technique in Milk Samples for the Diagnosis of Bovine Tuberculosis in Dairy Cattle Using a Bayesian Approach
Intra-Palpebral Tuberculin Skin Test and Interferon Gamma Release Assay in Diagnosing Tuberculosis Due to Mycobacterium caprae in European Bison (Bison bonasus)
Anna Didkowska, Blanka Orłowska, Monika Krajewska-Wędzina, Michał Krzysiak, Małgorzata Bruczyńska, Jan Wiśniewski, Daniel Klich, Wanda Olech and Krzysztof Anusz Pathogens 11(2) 260 (2022) https://doi.org/10.3390/pathogens11020260
Effect of the topical administration of corticosteroids and tuberculin pre-sensitisation on the diagnosis of tuberculosis in goats
The Occurrence of Mycobacterium avium Subspecies paratuberculosis Positive Milk Antibody ELISA Results in Dairy Cattle under Varying Time Periods after Skin Testing for Bovine Tuberculosis
The regression of the bovine tuberculin reaction: Results from the Reactor Quality Assurance study in Northern Ireland
Emily Courcier, Enzo Ascenzi, Alan Gordon, Liam Doyle, John Buchanan, Tom Ford, Mervyn Dunlop, Roly Harwood, Kate McAllister, Paddy McGuckian, Raymond Kirke, Felipe Ayastuy, Dermot McCaughey, Janet McKeown, Linda Quinn, Charlotte Smith, Fiona Young, David Corbett, Claire Barry and Fraser Menzies The Veterinary Journal 272 105664 (2021) https://doi.org/10.1016/j.tvjl.2021.105664
Characterization of potential superspreader farms for bovine tuberculosis: A review
Helen R. Fielding, Trevelyan J. McKinley, Richard J. Delahay, Matthew J. Silk and Robbie A. McDonald Veterinary Medicine and Science 7(2) 310 (2021) https://doi.org/10.1002/vms3.358
Cell-Mediated Immunological Biomarkers and Their Diagnostic Application in Livestock and Wildlife Infected With Mycobacterium bovis
Detection of bovine inflammatory cytokines IL-1β, IL-6, and TNF-α with a multiplex electrochemiluminescent assay platform
Carol G. Chitko-McKown, Stacy L. Bierman, Larry A. Kuehn, Gary L. Bennett, Keith D. DeDonder, Michael D. Apley, Gregory P. Harhay, Michael L. Clawson, Bradley J. White, Robert L. Larson, Sarah F. Capik and Brian V. Lubbers Veterinary Immunology and Immunopathology 237 110274 (2021) https://doi.org/10.1016/j.vetimm.2021.110274
Development of a Multiplex Bead Assay for Simultaneous Serodiagnosis of Antibodies against Mycobacterium bovis, Brucella suis, and Trichinella spiralis in Wild Boar
Antonia Touloudi, George Valiakos, Shaun Cawthraw, Polychronis Kostoulas, Christian Gortázar, Mariana Boadella, Alexios Giannakopoulos, Periklis Birtsas, Marina Sofia, Labrini V. Athanasiou, Maria Satra, Zoi Athanasakopoulou, Maria Kantere, Vassiliki Spyrou, Liljana Petrovska and Charalambos Billinis Microorganisms 9(5) 904 (2021) https://doi.org/10.3390/microorganisms9050904
Hydrophobic Mycobacterial Antigens Elicit Polyfunctional T Cells in Mycobacterium bovis Immunized Cattle: Association With Protection Against Challenge?
Association between results of diagnostic tests for bovine tuberculosis and Johne's disease in cattle
Catalina Picasso‐Risso, Ana Grau, Douwe Bakker, Jesus Nacar, Olga Mínguez, Andres Perez and Julio Alvarez Veterinary Record 185(22) 693 (2019) https://doi.org/10.1136/vr.105336
AN INTERFERON GAMMA RELEASE ASSAY FOR THE DETECTION OF IMMUNE SENSITIZATION TO MYCOBACTERIUM BOVIS IN AFRICAN WILD DOGS (LYCAON PICTUS)
Roxanne L. Higgitt, O. Louis van Schalkwyk, Lin-Mari deKlerk-Lorist, et al. Journal of Wildlife Diseases 55(3) 529 (2019) https://doi.org/10.7589/2018-03-089
Detection of Mycobacterium bovis infection in African buffaloes ( Syncerus caffer ) using QuantiFERON ® -TB Gold (QFT) tubes and the Qiagen cattletype ® IFN-gamma ELISA
Comparative analysis of adaptive immune responses following experimental infections of cattle with bovine viral diarrhoea virus-1 and an Asiatic atypical ruminant pestivirus
Victor Riitho, Magdalena Larska, Rebecca Strong, S. Anna La Rocca, Nicolas Locker, Stefan Alenius, Falko Steinbach, Lihong Liu, Åse Uttenthal and Simon P. Graham Vaccine 36(30) 4494 (2018) https://doi.org/10.1016/j.vaccine.2018.06.019
Modelling the variation in skin-test tuberculin reactions, post-mortem lesion counts and case pathology in tuberculosis-exposed cattle: Effects of animal characteristics, histories and co-infection
Is TB Testing Associated With Increased Blood Interferon-Gamma Levels?
Aideen E. Kennedy, Jim O’Mahony, Noel Byrne, John MacSharry and Riona G. Sayers Frontiers in Veterinary Science 4 (2017) https://doi.org/10.3389/fvets.2017.00176
Factors affecting the gamma interferon test in the detection of bovine tuberculosis in cattle
Geoffrey W. de Lisle, Richard S. Green and Bryce M. Buddle Journal of Veterinary Diagnostic Investigation 29(2) 198 (2017) https://doi.org/10.1177/1040638716689114
Potential for rapid antibody detection to identify tuberculous cattle with non-reactive tuberculin skin test results
Bovine tuberculosis visible lesions in cattle culled during herd breakdowns: the effects of individual characteristics, trade movement and co-infection
Risk factors for failure to detect bovine tuberculosis in cattle from infected herds across Northern Ireland (2004–2010)
Angela Lahuerta-Marin, James McNair, Robin Skuce, Stewart McBride, Michelle Allen, Sam A.J. Strain, Fraser D. Menzies, Stanley J.W. McDowell and Andrew W. Byrne Research in Veterinary Science 107 233 (2016) https://doi.org/10.1016/j.rvsc.2016.06.014
Effects of repeated comparative intradermal tuberculin testing on test results: a longitudinal study in TB-free red deer
Azlan Che-Amat, Maria Ángeles Risalde, David González-Barrio, Jose Antonio Ortíz and Christian Gortázar BMC Veterinary Research 12(1) (2016) https://doi.org/10.1186/s12917-016-0825-2
Mycobacterium bovis Infection of Cattle and White-Tailed Deer: Translational Research of Relevance to Human Tuberculosis
Specificity of the comparative skin test for bovine tuberculosis in Great Britain
A. V. Goodchild, S. H. Downs, P. Upton, J. L. N. Wood and R. de la Rua‐Domenech Veterinary Record 177(10) 258 (2015) https://doi.org/10.1136/vr.102961
Evaluation of the immunogenicity and diagnostic interference caused by M. tuberculosis SO2 vaccination against tuberculosis in goats
Javier Bezos, Carmen Casal, Eugenia Puentes, Alberto Díez-Guerrier, Beatriz Romero, Nacho Aguiló, Lucía de Juan, Carlos Martín and Lucas Domínguez Research in Veterinary Science 103 73 (2015) https://doi.org/10.1016/j.rvsc.2015.09.017
Use of Antigen-Specific Interleukin-2 To Differentiate between Cattle Vaccinated with Mycobacterium bovis BCG and Cattle Infected with M. bovis
Shelley G. Rhodes, Lucy C. McKinna, Sabine Steinbach, et al. Clinical and Vaccine Immunology 21(1) 39 (2014) https://doi.org/10.1128/CVI.00522-13
Transcript Levels of Major Interleukins in Relation to the Clinicopathological Profile of Patients with Tuberculous Intervertebral Discs and Healthy Controls
Innate cytokine profiling of bovine alveolar macrophages reveals commonalities and divergence in the response to Mycobacterium bovis and Mycobacterium tuberculosis infection
Tuberculin manufacturing source and breakdown incidence rate of bovine tuberculosis in British cattle, 2005–2009
S. H. Downs, R. S. Clifton‐Hadley, P. A. Upton, I. C. Milne, E. R. Ely, R. Gopal, A. V. Goodchild and A. R. Sayers Veterinary Record 172(4) 98 (2013) https://doi.org/10.1136/vr.100679
Ante-mortem diagnosis of caprine tuberculosis in persistently infected herds: Influence of lesion type on the sensitivity of diagnostic tests
Antonio J. Buendía, Jose A. Navarro, Jesus Salinas, Jim McNair, Lucia de Juan, Nieves Ortega, Paulina Cámara, Pilar Torreblanca and Joaquin Sanchez Research in Veterinary Science 95(3) 1107 (2013) https://doi.org/10.1016/j.rvsc.2013.10.003
Immunisation with ID83 fusion protein induces antigen-specific cell mediated and humoral immune responses in cattle
The influence of cattle breed on susceptibility to bovine tuberculosis in Ethiopia
Martin Vordermeier, Gobena Ameni, Stefan Berg, et al. Comparative Immunology, Microbiology and Infectious Diseases 35(3) 227 (2012) https://doi.org/10.1016/j.cimid.2012.01.003
Patterns of delayed detection and persistence of bovine tuberculosis in confirmed and unconfirmed herd breakdowns in cattle and cattle herds in Great Britain
Differential effects of Mycobacterium bovis - derived polar and apolar lipid fractions on bovine innate immune cells
Chris Pirson, Gareth J Jones, Sabine Steinbach, Gurdyal S Besra and H Vordermeier Veterinary Research 43(1) 54 (2012) https://doi.org/10.1186/1297-9716-43-54
Perspectives on the History of Bovine TB and the Role of Tuberculin in Bovine TB Eradication
Use of a multiplex enzyme-linked immunosorbent assay to detect a subpopulation of Mycobacterium bovis–infected animals deemed negative or inconclusive by the single intradermal comparative tuberculin skin test
Clare Whelan, Eduard Shuralev, Hang Fai Kwok, Kevin Kenny, Anthony Duignan, Margaret Good, William C. Davis and John Clarke Journal of Veterinary Diagnostic Investigation 23(3) 499 (2011) https://doi.org/10.1177/1040638711403410
Lack of correlation between BCG-induced tuberculin skin test sensitisation and protective immunity in cattle
Use of the Intradermal Tuberculin Test in a Herd of Captive elk (Cervus Elaphus Nelsoni) Naturally Infected with Mycobacterium Bovis
Mitchell V. Palmer, Diana L. Whipple, Janet B. Payeur and Carole A. Bolin Journal of Veterinary Diagnostic Investigation 23(2) 363 (2011) https://doi.org/10.1177/104063871102300230
Mycobacterium bovis antigens for the differential diagnosis of vaccinated and infected cattle
The comparative performance of the single intradermal test and the single intradermal comparative tuberculin test in Irish cattle, using tuberculin PPD combinations of differing potencies
Simultaneous Measurement of Antigen-Stimulated Interleukin-1β and Gamma Interferon Production Enhances Test Sensitivity for the Detection of
Mycobacterium bovis
Infection in Cattle
Gareth J. Jones, Chris Pirson, R. Glyn Hewinson and H. Martin Vordermeier Clinical and Vaccine Immunology 17(12) 1946 (2010) https://doi.org/10.1128/CVI.00377-10
Bovine tuberculosis: Effect of the tuberculin skin test on in vitro interferon gamma responses
Performance of the Enferplex TB Assay with Cattle in Great Britain and Assessment of Its Suitability as a Test To Distinguish Infected and Vaccinated Animals
