MAPPFinder 2.0 Results for the Gene Ontology File: C:\YannickB\PRV\HEK_PRV_Analyse\MAPP\GenMapp2_Beta\HEK-PRV_Source_Unigene-Avr2004.gex Table: HEK-PRV-DOWN-Avr 04-Criterion1-GO Database: C:\GenMAPP 2 Data\Gene Databases\Hs-Std_20031113.gdb colors:|HEK-PRV-042004| 11/6/2003 Homo sapiens Pvalues = false Calculation Summary: 1696 probes met the [SAM_Ord] <0 criteria. 1542 probes meeting the filter linked to a SwissProt ID. 3211 unique SwissProt genes met the criterion. 1297 genes meeting the criterion linked to a GO term. 9879 Probes in this dataset 8709 Probes linked to a SwissProt ID. 17979 genes in this dataset 6991 Genes linked to a GO term. The z score is based on an N of 6991 and a R of 1297 distinct genes in the GO. GOID GO Name GO Type Number Changed Local Number Measured Local Number in GO Local Percent Changed Local Percent Present Local Number Changed Number Measured Number in GO Percent Changed Percent Present Z Score PermuteP AdjustedP 0005737 cytoplasm C 87 377 601 23.07692 62.72879 479 1758 2986 27.24687 58.87475 10.839 0 0 0015078 hydrogen ion transporter activity F 14 21 32 66.66666 65.625 49 73 154 67.12329 47.4026 10.731 0 0 0005622 intracellular C 49 235 665 20.85106 35.33834 763 3212 6357 23.75467 50.52698 10.315 0 0 0015077 monovalent inorganic cation transporter activity F 0 1 4 0 25 50 79 164 63.29114 48.17073 10.287 0 0 0005783 endoplasmic reticulum C 59 166 260 35.54217 63.84615 97 232 362 41.81034 64.08839 9.268 0 0 0005739 mitochondrion C 113 296 445 38.17567 66.51685 126 335 541 37.61194 61.92237 9.197 0 0 0005837 26S proteasome C 25 30 35 83.33334 85.71429 25 30 35 83.33334 85.71429 9.147 0 0 0030529 ribonucleoprotein complex C 17 29 46 58.62069 63.04348 80 181 334 44.19889 54.19162 8.993 0 0 0000278 mitotic cell cycle P 0 0 0 0 0 81 196 354 41.32653 55.36723 8.319 0 0 0000398 nuclear mRNA splicing\, via spliceosome P 27 49 71 55.10204 69.01408 35 60 86 58.33333 69.76744 7.961 0 0 0000375 RNA splicing\, via transesterification reactions P 0 0 0 0 0 35 60 86 58.33333 69.76744 7.961 0 0 0000377 RNA splicing\, via transesterification reactions with bulged adenosine as nucleophile P 0 0 0 0 0 35 60 86 58.33333 69.76744 7.961 0 0 0003723 RNA binding F 82 254 450 32.28347 56.44444 112 315 560 35.55556 56.25 7.944 0 0 0006396 RNA processing P 14 37 67 37.83784 55.22388 67 159 273 42.13836 58.24176 7.739 0 0 0008380 RNA splicing P 4 7 13 57.14286 53.84615 36 65 97 55.38462 67.01031 7.674 0 0 0003729 mRNA binding F 8 9 11 88.88889 81.81818 37 70 95 52.85714 73.68421 7.42 0 0 0016070 RNA metabolism P 0 2 3 0 66.66666 70 175 297 40 58.92256 7.391 0 0 0008324 cation transporter activity F 2 8 26 25 30.76923 59 138 276 42.75362 50 7.386 0 0 0008137 NADH dehydrogenase (ubiquinone) activity F 19 26 54 73.07692 48.14815 19 26 54 73.07692 48.14815 7.165 0 0 0046907 intracellular transport P 0 0 0 0 0 101 294 508 34.35374 57.87402 7.121 0 0 0000502 proteasome complex (sensu Eukarya) C 1 1 1 100 100 17 22 30 77.27273 73.33334 7.096 0 0 0009141 nucleoside triphosphate metabolism P 0 0 0 0 0 21 31 54 67.74194 57.40741 7.061 0 0 0008370 obsolete cellular component C 0 0 0 0 0 55 130 167 42.30769 77.84431 7.033 0 0 0016655 oxidoreductase activity\, acting on NADH or NADPH\, quinone or similar compound as acceptor F 0 0 0 0 0 20 29 57 68.96552 50.87719 6.998 0 0 0015399 primary active transporter activity F 0 0 0 0 0 54 128 264 42.1875 48.48485 6.942 0 0 0006397 mRNA processing P 9 29 44 31.03448 65.90909 44 96 137 45.83333 70.07299 6.924 0 0 0008565 protein transporter activity F 63 165 264 38.18182 62.5 69 180 285 38.33333 63.15789 6.916 0 0 0015031 protein transport P 5 18 36 27.77778 50 90 258 421 34.88372 61.28266 6.876 0 0 0016651 oxidoreductase activity\, acting on NADH or NADPH F 0 0 0 0 0 25 42 77 59.52381 54.54546 6.851 0 0 0008248 pre-mRNA splicing factor activity F 28 50 71 56 70.42254 28 50 71 56 70.42254 6.836 0 0 0009144 purine nucleoside triphosphate metabolism P 0 0 0 0 0 20 30 48 66.66666 62.5 6.794 0 0 0009205 purine ribonucleoside triphosphate metabolism P 0 0 0 0 0 20 30 48 66.66666 62.5 6.794 0 0 0009199 ribonucleoside triphosphate metabolism P 0 0 0 0 0 20 30 48 66.66666 62.5 6.794 0 0 0006163 purine nucleotide metabolism P 0 1 1 0 100 24 40 69 60 57.97102 6.762 0 0 0009259 ribonucleotide metabolism P 0 0 0 0 0 24 40 69 60 57.97102 6.762 0 0 0009260 ribonucleotide biosynthesis P 0 0 0 0 0 22 35 63 62.85714 55.55556 6.759 0 0 0006886 intracellular protein transport P 63 173 294 36.41618 58.84354 85 242 386 35.12397 62.6943 6.749 0 0 0009206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 18 26 43 69.23077 60.46511 6.66 0 0 0009145 purine nucleoside triphosphate biosynthesis P 0 0 0 0 0 18 26 43 69.23077 60.46511 6.66 0 0 0009201 ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 18 26 43 69.23077 60.46511 6.66 0 0 0009142 nucleoside triphosphate biosynthesis P 2 2 3 100 66.66666 18 26 44 69.23077 59.09091 6.66 0 0 0003954 NADH dehydrogenase activity F 18 26 36 69.23077 72.22222 18 26 36 69.23077 72.22222 6.66 0 0 0015081 sodium ion transporter activity F 0 2 2 0 100 19 29 57 65.51724 50.87719 6.519 0 0 0006164 purine nucleotide biosynthesis P 2 3 10 66.66666 30 21 34 61 61.76471 55.73771 6.497 0 0 0015075 ion transporter activity F 2 11 17 18.18182 64.70588 66 177 379 37.28814 46.70185 6.495 0 0 0016469 proton-transporting two-sector ATPase complex C 6 8 9 75 88.88889 13 16 20 81.25 80 6.459 0 0 0009150 purine ribonucleotide metabolism P 0 0 0 0 0 21 35 62 60 56.45161 6.323 0 0 0000087 M phase of mitotic cell cycle P 1 2 3 50 66.66666 36 78 114 46.15385 68.42105 6.306 0 0 0006818 hydrogen transport P 0 0 0 0 0 24 43 89 55.81395 48.31461 6.305 0 0 0046034 ATP metabolism P 1 3 4 33.33333 75 15 21 34 71.42857 61.76471 6.242 0 0 0016659 oxidoreductase activity\, acting on NADH or NADPH\, other acceptor F 0 0 0 0 0 18 28 38 64.28571 73.68421 6.238 0 0 0007067 mitosis P 28 55 78 50.90909 70.51282 35 76 111 46.05263 68.46847 6.201 0 0 0000067 DNA replication and chromosome cycle P 1 5 6 20 83.33334 46 112 225 41.07143 49.77778 6.18 0 0 0006754 ATP biosynthesis P 11 14 22 78.57143 63.63636 13 17 29 76.47059 58.62069 6.15 0 0 0006753 nucleoside phosphate metabolism P 0 0 0 0 0 13 17 29 76.47059 58.62069 6.15 0 0 0009152 purine ribonucleotide biosynthesis P 1 1 1 100 100 19 31 57 61.29032 54.38596 6.135 0 0 0015992 proton transport P 21 39 82 53.84615 47.56097 23 42 88 54.76191 47.72727 6.055 0 0 0007028 cytoplasm organization and biogenesis P 0 0 0 0 0 68 193 369 35.23316 52.30352 6.045 0 0 0005635 nuclear membrane C 4 14 22 28.57143 63.63636 25 48 72 52.08333 66.66666 5.996 0 0 0005681 spliceosome complex C 13 22 40 59.09091 55 17 27 46 62.96296 58.69565 5.948 0 0 0009058 biosynthesis P 4 24 66 16.66667 36.36364 166 603 1112 27.52902 54.22662 5.932 0 0 0016043 cell organization and biogenesis P 0 0 0 0 0 96 306 631 31.37255 48.49445 5.899 0 0 0005839 proteasome core complex (sensu Eukarya) C 12 16 22 75 72.72727 12 16 22 75 72.72727 5.815 0 0 0012505 endomembrane system C 0 1 1 0 100 39 95 151 41.05263 62.91391 5.68 0 0 0006511 ubiquitin-dependent protein catabolism P 30 67 140 44.77612 47.85714 31 69 143 44.92754 48.25175 5.664 0 0 0019941 modification-dependent protein catabolism P 0 0 0 0 0 31 69 143 44.92754 48.25175 5.664 0 0 0009165 nucleotide biosynthesis P 2 6 12 33.33333 50 26 54 102 48.14815 52.94118 5.616 0 0 0016817 hydrolase activity\, acting on acid anhydrides F 0 0 0 0 0 96 315 688 30.47619 45.78489 5.571 0 0 0006752 group transfer coenzyme metabolism P 0 0 0 0 0 16 27 43 59.25926 62.7907 5.452 0 0 0000245 spliceosome assembly P 6 8 13 75 61.53846 10 13 19 76.92308 68.42105 5.419 0 0 0005753 proton-transporting ATP synthase complex (sensu Eukarya) C 9 11 12 81.81818 91.66666 9 11 14 81.81818 78.57143 5.402 0 0 0045255 hydrogen-translocating F-type ATPase complex C 0 0 0 0 0 9 11 14 81.81818 78.57143 5.402 0 0 0045259 proton-transporting ATP synthase complex C 0 0 0 0 0 9 11 14 81.81818 78.57143 5.402 0 0 0000280 nuclear division P 0 0 0 0 0 38 96 141 39.58333 68.08511 5.337 0 0 0000279 M phase P 0 1 3 0 33.33333 39 100 150 39 66.66666 5.298 0 0 0016818 hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides F 0 0 0 0 0 90 298 653 30.20134 45.63553 5.287 0 0 0006996 organelle organization and biogenesis P 1 2 3 50 66.66666 58 170 325 34.11765 52.30769 5.285 0 0 0046930 pore complex C 0 0 0 0 0 16 28 42 57.14286 66.66666 5.263 0 0 0005643 nuclear pore C 16 28 43 57.14286 65.11628 16 28 43 57.14286 65.11628 5.263 0 0 0005761 mitochondrial ribosome C 3 6 7 50 85.71429 11 16 26 68.75 61.53846 5.171 0 0 0000313 organellar ribosome C 0 0 0 0 0 11 16 26 68.75 61.53846 5.171 0 0 0007049 cell cycle P 27 77 156 35.06493 49.35897 111 392 716 28.31633 54.7486 5.118 0 0 0030532 small nuclear ribonucleoprotein complex C 6 8 12 75 66.66666 10 14 19 71.42857 73.68421 5.094 0 0 0009117 nucleotide metabolism P 2 8 15 25 53.33333 30 72 141 41.66667 51.06383 5.071 0 0 0008436 heterogeneous nuclear ribonucleoprotein F 9 12 14 75 85.71429 9 12 14 75 85.71429 5.034 0 0 0009108 coenzyme biosynthesis P 0 0 2 0 0 18 35 73 51.42857 47.94521 5.016 0 0 0006260 DNA replication P 21 50 94 42 53.19149 33 83 186 39.75904 44.62366 5 0 0 0000084 S phase of mitotic cell cycle P 0 1 2 0 50 33 83 187 39.75904 44.38503 5 0 0 0005829 cytosol C 41 115 156 35.65217 73.71795 62 193 283 32.12435 68.19788 4.918 0 0 0006259 DNA metabolism P 2 16 23 12.5 69.56522 83 280 614 29.64286 45.60261 4.872 0 0 0005759 mitochondrial matrix C 8 19 29 42.10526 65.51724 20 42 64 47.61905 65.625 4.86 0 0 0005732 small nucleolar ribonucleoprotein complex C 10 15 27 66.66666 55.55556 10 15 27 66.66666 55.55556 4.799 0 0 0016491 oxidoreductase activity F 79 250 472 31.6 52.9661 101 359 748 28.13371 47.99465 4.795 0 0 0005634 nucleus C 286 1391 2847 20.56075 48.85845 350 1541 3107 22.71252 49.59768 4.758 0 0 0006446 regulation of translational initiation P 13 22 33 59.09091 66.66666 13 23 34 56.52174 67.64706 4.692 0 0 0004576 oligosaccharyl transferase activity F 2 2 5 100 40 5 5 8 100 62.5 4.686 0 0 0006119 oxidative phosphorylation P 1 1 4 100 25 11 18 52 61.11111 34.61538 4.651 0 0 0005489 electron transporter activity F 35 138 331 25.36232 41.69184 56 175 382 32 45.81152 4.634 0 0 0046138 coenzymes and prosthetic group biosynthesis P 0 0 0 0 0 20 44 89 45.45454 49.4382 4.605 0 0 0005525 GTP binding F 51 156 348 32.69231 44.82759 51 156 348 32.69231 44.82759 4.594 0 0 0006445 regulation of translation P 5 12 21 41.66667 57.14286 19 41 66 46.34146 62.12121 4.591 0 0 0019866 inner membrane C 8 17 29 47.05882 58.62069 25 61 126 40.98361 48.4127 4.526 0 0 0046873 metal ion transporter activity F 2 8 19 25 42.10526 25 61 104 40.98361 58.65385 4.526 0 0 0003735 structural constituent of ribosome F 41 119 240 34.45378 49.58333 41 119 240 34.45378 49.58333 4.501 0 0 0006412 protein biosynthesis P 42 132 243 31.81818 54.32099 89 316 597 28.16456 52.93132 4.498 0 0 0009059 macromolecule biosynthesis P 0 0 0 0 0 89 316 597 28.16456 52.93132 4.498 0 0 0017076 purine nucleotide binding F 0 1 1 0 100 197 813 1892 24.23124 42.9704 4.431 0 0 0005743 mitochondrial inner membrane C 4 24 59 16.66667 40.67797 22 52 113 42.30769 46.0177 4.423 0 0 0019001 guanyl nucleotide binding F 0 0 0 0 0 51 160 353 31.875 45.32578 4.385 0 0 0005740 mitochondrial membrane C 3 7 13 42.85714 53.84615 28 73 159 38.35616 45.91195 4.375 0 0 0006913 nucleocytoplasmic transport P 1 1 1 100 100 20 46 65 43.47826 70.76923 4.363 0 0 0003743 translation initiation factor activity F 19 43 71 44.18605 60.56338 19 43 71 44.18605 60.56338 4.337 0 0 0045182 translation regulator activity F 1 1 1 100 100 27 70 114 38.57143 61.40351 4.33 0 0 0003754 chaperone activity F 22 58 118 37.93103 49.15254 33 92 169 35.86956 54.43787 4.301 0 0 0000166 nucleotide binding F 24 79 176 30.37975 44.88636 197 820 1910 24.02439 42.93194 4.29 0 0 0006099 tricarboxylic acid cycle P 10 17 29 58.82353 58.62069 10 17 29 58.82353 58.62069 4.276 0 0 0006605 protein targeting P 11 34 44 32.35294 77.27273 31 86 112 36.04651 76.78571 4.199 0 0 0008135 translation factor activity\, nucleic acid binding F 1 4 5 25 80 26 68 112 38.23529 60.71429 4.196 0 0 0008575 proteasome ATPase activity F 4 4 4 100 100 4 4 4 100 100 4.191 0 0 0016462 pyrophosphatase activity F 1 1 12 100 8.333333 4 4 16 100 25 4.191 0 0 0008152 metabolism P 34 185 456 18.37838 40.57018 721 3523 7651 20.46551 46.04627 4.147 0 0 0007059 chromosome segregation P 5 9 13 55.55556 69.23077 9 15 21 60 71.42857 4.134 0 0 0006129 protein-disulfide reduction P 1 1 1 100 100 9 15 44 60 34.09091 4.134 0 0 0006371 mRNA splicing P 15 32 46 46.875 69.56522 15 32 46 46.875 69.56522 4.131 0 0 0050657 nucleic acid transport P 0 0 0 0 0 6 8 17 75 47.05882 4.109 0 0 0005763 mitochondrial small ribosomal subunit C 6 8 13 75 61.53846 6 8 13 75 61.53846 4.109 0 0 0006405 RNA-nucleus export P 2 2 2 100 100 6 8 17 75 47.05882 4.109 0 0 0006403 RNA localization P 0 0 0 0 0 6 8 17 75 47.05882 4.109 0 0 0008553 hydrogen-exporting ATPase activity\, phosphorylative mechanism F 6 8 12 75 66.66666 6 8 12 75 66.66666 4.109 0 0 0006612 protein-membrane targeting P 2 2 2 100 100 6 8 9 75 88.88889 4.109 0 0 0050658 RNA transport P 0 0 0 0 0 6 8 17 75 47.05882 4.109 0 0 0000314 organellar small ribosomal subunit C 0 0 0 0 0 6 8 13 75 61.53846 4.109 0 0 0006732 coenzyme metabolism P 0 0 0 0 0 22 55 110 40 50 4.108 0 0 0005788 endoplasmic reticulum lumen C 5 6 11 83.33334 54.54546 5 6 11 83.33334 54.54546 4.084 0 0 0006091 energy pathways P 23 73 89 31.50685 82.02247 47 151 225 31.12583 67.11111 4.018 0 0 0004842 ubiquitin-protein ligase activity F 19 46 116 41.30435 39.65517 19 46 116 41.30435 39.65517 3.983 0 0 0006731 coenzymes and prosthetic group metabolism P 0 0 0 0 0 25 67 129 37.31343 51.93798 3.969 0 0 0008151 cell growth and/or maintenance P 21 133 249 15.78947 53.41365 411 1909 3822 21.5296 49.94767 3.925 0 0 0006413 translational initiation P 4 17 31 23.52941 54.83871 17 40 64 42.5 62.5 3.907 0 0 0003777 microtubule motor activity F 8 15 48 53.33333 31.25 9 16 52 56.25 30.76923 3.883 0 0 0000910 cytokinesis P 19 46 94 41.30435 48.93617 19 47 95 40.42553 49.47368 3.87 0 0 0005215 transporter activity F 34 174 418 19.54023 41.62679 226 984 2128 22.96748 46.2406 3.843 0 0 0006092 main pathways of carbohydrate metabolism P 0 0 2 0 0 22 58 108 37.93103 53.7037 3.812 0 0 0042775 ATP synthesis coupled electron transport (sensu Eukarya) P 0 0 0 0 0 8 14 43 57.14286 32.55814 3.718 0 0 0042773 ATP synthesis coupled electron transport P 0 0 0 0 0 8 14 43 57.14286 32.55814 3.718 0 0 0015931 nucleobase\, nucleoside\, nucleotide and nucleic acid transport P 0 0 0 0 0 8 14 24 57.14286 58.33333 3.718 0 0 0006120 mitochondrial electron transport\, NADH to ubiquinone P 8 14 36 57.14286 38.88889 8 14 36 57.14286 38.88889 3.718 0 0 0003824 catalytic activity F 14 69 225 20.28986 30.66667 516 2470 5598 20.89069 44.1229 3.717 0 0 0003925 small monomeric GTPase activity F 8 26 71 30.76923 36.61972 30 89 196 33.70787 45.40816 3.701 0 0 0006457 protein folding P 26 74 151 35.13514 49.00662 26 74 151 35.13514 49.00662 3.689 0 0 0005730 nucleolus C 7 28 40 25 70 19 49 77 38.77551 63.63636 3.654 0 0 0004579 dolichyl-diphosphooligosaccharide-protein glycosyltransferase activity F 3 3 3 100 100 3 3 3 100 100 3.63 0 0 0019961 interferon binding F 0 0 0 0 0 3 3 4 100 75 3.63 0 0 0004904 interferon receptor activity F 0 0 0 0 0 3 3 4 100 75 3.63 0 0 0008607 phosphorylase kinase\, intrinsic regulator activity F 3 3 3 100 100 3 3 3 100 100 3.63 0 0 0030508 thiol-disulfide exchange intermediate activity F 3 3 3 100 100 3 3 3 100 100 3.63 0 0 0008250 oligosaccharyl transferase complex C 3 3 3 100 100 3 3 3 100 100 3.63 0 0 0042254 ribosome biogenesis and assembly P 0 0 0 0 0 10 20 37 50 54.05405 3.623 0 0 0007046 ribosome biogenesis P 3 4 8 75 50 10 20 37 50 54.05405 3.623 0 0 0016881 acid-D-amino acid ligase activity F 0 0 0 0 0 20 53 139 37.73585 38.1295 3.606 0 0 0006261 DNA dependent DNA replication P 3 8 8 37.5 100 18 46 80 39.13044 57.5 3.602 0 0 0005746 mitochondrial electron transport chain C 4 5 14 80 35.71429 5 7 26 71.42857 26.92308 3.6 0 0 0007051 spindle assembly P 0 0 0 0 0 5 7 11 71.42857 63.63636 3.6 0 0 0007052 mitotic spindle assembly P 3 4 8 75 50 5 7 11 71.42857 63.63636 3.6 0 0 0008304 eukaryotic translation initiation factor 4 complex C 5 7 9 71.42857 77.77778 5 7 9 71.42857 77.77778 3.6 0 0 0005637 nuclear inner membrane C 1 1 1 100 100 5 7 7 71.42857 100 3.6 0 0 0003924 GTPase activity F 3 16 36 18.75 44.44444 41 135 287 30.37037 47.03833 3.567 0 0 0006221 pyrimidine nucleotide biosynthesis P 1 2 6 50 33.33333 7 12 23 58.33333 52.17391 3.548 0 0 0042175 nuclear envelope-endoplasmic reticulum network C 0 0 0 0 0 14 33 48 42.42424 68.75 3.536 0 0 0006376 mRNA splice site selection P 4 5 6 80 83.33334 4 5 6 80 83.33334 3.536 0 0 0005838 proteasome regulatory particle (sensu Eukarya) C 4 5 7 80 71.42857 4 5 7 80 71.42857 3.536 0 0 0005487 nucleocytoplasmic transporter activity F 4 5 6 80 83.33334 4 5 6 80 83.33334 3.536 0 0 0005844 polysome C 4 5 5 80 100 4 5 5 80 100 3.536 0 0 0016887 ATPase activity F 2 9 25 22.22222 36 44 148 334 29.72973 44.31138 3.535 0 0 0005654 nucleoplasm C 11 27 39 40.74074 69.23077 39 128 204 30.46875 62.7451 3.5 0 0 0005789 endoplasmic reticulum membrane C 7 21 33 33.33333 63.63636 13 30 45 43.33333 66.66666 3.499 0 0 0016874 ligase activity F 31 82 156 37.80488 52.5641 38 124 298 30.64516 41.61074 3.495 0 0 0005840 ribosome C 29 89 172 32.58427 51.74419 35 112 214 31.25 52.33645 3.485 0 0 0042623 ATPase activity\, coupled F 0 0 0 0 0 43 145 327 29.65517 44.34251 3.475 0 0 0015935 small ribosomal subunit C 4 4 8 100 50 14 34 51 41.17647 66.66666 3.402 0 0 0007032 endosome organization and biogenesis P 0 0 1 0 0 6 10 16 60 62.5 3.374 0 0 0009220 pyrimidine ribonucleotide biosynthesis P 1 1 1 100 100 6 10 14 60 71.42857 3.374 0 0 0016197 endosome transport P 2 4 5 50 80 6 10 15 60 66.66666 3.374 0 0 0045045 secretory pathway P 0 1 2 0 50 22 63 105 34.92064 60 3.357 0 0 0007264 small GTPase mediated signal transduction P 30 95 224 31.57895 42.41071 38 127 267 29.92126 47.56554 3.326 0 0 0005699 kinetochore C 7 13 14 53.84615 92.85714 7 13 14 53.84615 92.85714 3.276 0 0 0000059 protein-nucleus import\, docking P 7 13 18 53.84615 72.22222 7 13 18 53.84615 72.22222 3.276 0 0 0009069 serine family amino acid metabolism P 0 0 0 0 0 8 16 28 50 57.14286 3.239 0 0 0005386 carrier activity F 2 10 16 20 62.5 67 255 564 26.27451 45.21276 3.231 0 0 0004840 ubiquitin conjugating enzyme activity F 15 39 71 38.46154 54.92958 15 39 71 38.46154 54.92958 3.207 0 0 0045047 protein-ER targeting P 0 0 0 0 0 5 8 9 62.5 88.88889 3.199 0 0 0007029 ER organization and biogenesis P 0 0 0 0 0 5 8 9 62.5 88.88889 3.199 0 0 0006096 glycolysis P 12 29 55 41.37931 52.72727 12 29 55 41.37931 52.72727 3.169 0 0 0007017 microtubule-based process P 1 5 9 20 55.55556 16 43 124 37.2093 34.67742 3.157 0 0 0000082 G1/S transition of mitotic cell cycle P 5 8 14 62.5 57.14286 14 36 53 38.88889 67.92453 3.147 0 0 0006281 DNA repair P 20 73 116 27.39726 62.93103 34 114 204 29.82456 55.88235 3.121 0 0 0008639 small protein conjugating enzyme activity F 0 0 1 0 0 15 40 73 37.5 54.79452 3.091 0 0 0015036 disulfide oxidoreductase activity F 3 12 21 25 57.14286 10 23 34 43.47826 67.64706 3.08 0 0 0003697 single-stranded DNA binding F 10 23 30 43.47826 76.66666 10 23 30 43.47826 76.66666 3.08 0 0 0000226 microtubule cytoskeleton organization and biogenesis P 2 5 13 40 38.46154 10 23 49 43.47826 46.93877 3.08 0 0 0004129 cytochrome-c oxidase activity F 6 11 28 54.54546 39.28571 6 11 28 54.54546 39.28571 3.073 0 0 0016676 oxidoreductase activity\, acting on heme group of donors\, oxygen as acceptor F 0 0 0 0 0 6 11 28 54.54546 39.28571 3.073 0 0 0015002 heme-copper terminal oxidase activity F 0 0 0 0 0 6 11 28 54.54546 39.28571 3.073 0 0 0009218 pyrimidine ribonucleotide metabolism P 0 0 0 0 0 6 11 15 54.54546 73.33334 3.073 0 0 0016675 oxidoreductase activity\, acting on heme group of donors F 0 0 0 0 0 6 11 28 54.54546 39.28571 3.073 0 0 0004683 calmodulin regulated protein kinase activity F 0 0 1 0 0 6 11 19 54.54546 57.89474 3.073 0 0 0006974 response to DNA damage stimulus P 1 5 11 20 45.45454 38 132 237 28.78788 55.6962 3.054 0 0 0009719 response to endogenous stimulus P 0 0 0 0 0 38 132 236 28.78788 55.93221 3.054 0 0 0005478 intracellular transporter activity F 3 9 16 33.33333 56.25 9 20 28 45 71.42857 3.047 0 0 0005623 cell C 0 2 2 0 100 934 4787 10473 19.51118 45.70801 3.039 0 0 0019538 protein metabolism P 2 10 15 20 66.66666 288 1343 2803 21.44453 47.91295 3.033 0 0 0006613 cotranslational membrane targeting P 4 6 7 66.66666 85.71429 4 6 7 66.66666 85.71429 3.033 0 0 0006406 mRNA-nucleus export P 4 6 14 66.66666 42.85714 4 6 14 66.66666 42.85714 3.033 0 0 0005684 major (U2-dependent) spliceosome C 0 0 0 0 0 4 6 7 66.66666 85.71429 3.033 0 0 0005224 ATP-binding and phosphorylation-dependent chloride channel activity F 4 6 7 66.66666 85.71429 4 6 7 66.66666 85.71429 3.033 0 0 0003857 3-hydroxyacyl-CoA dehydrogenase activity F 4 6 6 66.66666 100 4 6 6 66.66666 100 3.033 0 0 0000070 mitotic chromosome segregation P 4 6 8 66.66666 75 4 6 8 66.66666 75 3.033 0 0 0006302 double-strand break repair P 4 4 8 100 50 4 6 14 66.66666 42.85714 3.033 0 0 0046365 monosaccharide catabolism P 0 0 0 0 0 14 37 69 37.83784 53.62319 3.026 0 0 0046164 alcohol catabolism P 0 0 0 0 0 14 37 69 37.83784 53.62319 3.026 0 0 0007010 cytoskeleton organization and biogenesis P 4 19 44 21.05263 43.18182 33 112 243 29.46428 46.09053 2.995 0 0 0016209 antioxidant activity F 1 3 3 33.33333 100 11 27 54 40.74074 50 2.972 0 0 0003683 lamin/chromatin binding F 2 2 4 100 50 2 2 4 100 50 2.963 0 0 0000069 centromere/kinetochore complex maturation P 2 2 4 100 50 2 2 4 100 50 2.963 0 0 0000776 kinetochore C 2 2 2 100 100 2 2 2 100 100 2.963 0 0 0008334 histone mRNA metabolism P 1 1 1 100 100 2 2 2 100 100 2.963 0 0 0005638 lamin filament C 2 2 2 100 100 2 2 2 100 100 2.963 0 0 0005521 lamin binding F 2 2 5 100 40 2 2 5 100 40 2.963 0 0 0016681 oxidoreductase activity\, acting on diphenols and related substances as donors\, cytochrome as acceptor F 0 0 0 0 0 2 2 14 100 14.28571 2.963 0 0 0007030 Golgi organization and biogenesis P 2 2 7 100 28.57143 2 2 7 100 28.57143 2.963 0 0 0008278 cohesin complex C 1 1 1 100 100 2 2 2 100 100 2.963 0 0 0003763 chaperonin ATPase activity F 2 2 2 100 100 2 2 2 100 100 2.963 0 0 0005652 nuclear lamina C 0 0 2 0 0 2 2 4 100 50 2.963 0 0 0016679 oxidoreductase activity\, acting on diphenols and related substances as donors F 0 0 0 0 0 2 2 14 100 14.28571 2.963 0 0 0006390 transcription from mitochondrial promoter P 1 1 1 100 100 2 2 2 100 100 2.963 0 0 0019964 interferon-gamma binding F 0 0 0 0 0 2 2 2 100 100 2.963 0 0 0005686 snRNP U2 C 2 2 2 100 100 2 2 2 100 100 2.963 0 0 0005762 mitochondrial large ribosomal subunit C 2 2 6 100 33.33333 2 2 6 100 33.33333 2.963 0 0 0004462 lactoylglutathione lyase activity F 2 2 5 100 40 2 2 5 100 40 2.963 0 0 0046502 uroporphyrinogen III metabolism P 0 0 0 0 0 2 2 2 100 100 2.963 0 0 0009071 serine family amino acid catabolism P 0 0 0 0 0 2 2 4 100 50 2.963 0 0 0016601 RAC protein signal transduction P 2 2 2 100 100 2 2 2 100 100 2.963 0 0 0006780 uroporphyrinogen III biosynthesis P 1 1 1 100 100 2 2 2 100 100 2.963 0 0 0008600 protein phosphatase type 2A\, intrinsic catalyst activity F 2 2 2 100 100 2 2 2 100 100 2.963 0 0 0008379 thioredoxin peroxidase activity F 2 2 2 100 100 2 2 2 100 100 2.963 0 0 0016272 prefoldin complex C 2 2 8 100 25 2 2 8 100 25 2.963 0 0 0005093 RAB GDP-dissociation inhibitor activity F 2 2 2 100 100 2 2 2 100 100 2.963 0 0 0005960 glycine cleavage complex C 2 2 2 100 100 2 2 3 100 66.66666 2.963 0 0 0006546 glycine catabolism P 2 2 3 100 66.66666 2 2 3 100 66.66666 2.963 0 0 0016600 flotillin complex C 2 2 2 100 100 2 2 2 100 100 2.963 0 0 0008077 Hsp70/Hsp90 organizing protein activity F 2 2 3 100 66.66666 2 2 3 100 66.66666 2.963 0 0 0004307 ethanolaminephosphotransferase activity F 2 2 2 100 100 2 2 2 100 100 2.963 0 0 0009129 pyrimidine nucleoside monophosphate metabolism P 0 0 0 0 0 2 2 4 100 50 2.963 0 0 0009619 resistance to pathogenic bacteria P 2 2 2 100 100 2 2 2 100 100 2.963 0 0 0009130 pyrimidine nucleoside monophosphate biosynthesis P 0 0 0 0 0 2 2 4 100 50 2.963 0 0 0006904 nonselective vesicle docking P 2 2 8 100 25 2 2 8 100 25 2.963 0 0 0000022 mitotic spindle elongation P 2 2 2 100 100 2 2 2 100 100 2.963 0 0 0042147 retrograde (endosome to Golgi) transport P 2 2 3 100 66.66666 2 2 3 100 66.66666 2.963 0 0 0009262 deoxyribonucleotide metabolism P 0 0 0 0 0 2 2 13 100 15.38461 2.963 0 0 0009219 pyrimidine deoxyribonucleotide metabolism P 0 0 0 0 0 2 2 10 100 20 2.963 0 0 0000315 organellar large ribosomal subunit C 0 0 0 0 0 2 2 6 100 33.33333 2.963 0 0 0005769 early endosome C 2 2 5 100 40 2 2 5 100 40 2.963 0 0 0016895 exodeoxyribonuclease activity\, producing 5’-phosphomonoesters F 0 0 0 0 0 2 2 2 100 100 2.963 0 0 0008121 ubiquinol-cytochrome-c reductase activity F 2 2 14 100 14.28571 2 2 14 100 14.28571 2.963 0 0 0004529 exodeoxyribonuclease activity F 0 0 0 0 0 2 2 2 100 100 2.963 0 0 0016599 caveolar membrane C 0 0 0 0 0 2 2 2 100 100 2.963 0 0 0004906 interferon-gamma receptor activity F 2 2 2 100 100 2 2 2 100 100 2.963 0 0 0004774 succinate-CoA ligase activity F 0 0 0 0 0 2 2 3 100 66.66666 2.963 0 0 0007001 chromosome organization and biogenesis (sensu Eukarya) P 7 20 76 35 26.31579 26 84 224 30.95238 37.5 2.941 0 0 0006606 protein-nucleus import P 4 11 14 36.36364 78.57143 14 38 49 36.84211 77.55102 2.908 0 0 0006301 postreplication repair P 3 4 4 75 100 3 4 4 75 100 2.905 0 0 0046982 protein heterodimerization activity F 3 4 8 75 50 3 4 8 75 50 2.905 0 0 0017169 CDP-alcohol phosphatidyltransferase activity F 0 0 0 0 0 3 4 4 75 100 2.905 0 0 0016575 histone deacetylation P 3 4 7 75 57.14286 3 4 7 75 57.14286 2.905 0 0 0005791 rough endoplasmic reticulum C 1 2 2 50 100 3 4 5 75 80 2.905 0 0 0016615 malate dehydrogenase activity F 0 0 1 0 0 3 4 6 75 66.66666 2.905 0 0 0004448 isocitrate dehydrogenase activity F 0 0 0 0 0 3 4 9 75 44.44444 2.905 0 0 0005901 caveola C 2 3 4 66.66666 75 3 4 5 75 80 2.905 0 0 0007016 cytoskeletal anchoring P 3 4 10 75 40 3 4 10 75 40 2.905 0 0 0006275 regulation of DNA replication P 2 2 3 100 66.66666 3 4 6 75 66.66666 2.905 0 0 0046961 hydrogen-transporting ATPase activity\, rotational mechanism F 3 4 4 75 100 3 4 4 75 100 2.905 0 0 0004684 calmodulin-dependent protein kinase I activity F 3 4 7 75 57.14286 3 4 7 75 57.14286 2.905 0 0 0006544 glycine metabolism P 0 1 5 0 20 3 4 10 75 40 2.905 0 0 0006354 RNA elongation P 3 4 6 75 66.66666 3 4 6 75 66.66666 2.905 0 0 0005694 chromosome C 3 8 48 37.5 16.66667 19 57 163 33.33333 34.96933 2.882 0 0 0004601 peroxidase activity F 9 21 47 42.85714 44.68085 9 21 47 42.85714 44.68085 2.869 0 0 0003724 RNA helicase activity F 3 7 9 42.85714 77.77778 9 21 29 42.85714 72.4138 2.869 0 0 0006360 transcription from Pol I promoter P 0 3 4 0 75 9 21 36 42.85714 58.33333 2.869 0 0 0016879 ligase activity\, forming carbon-nitrogen bonds F 0 0 0 0 0 22 69 173 31.88406 39.88439 2.863 0 0 0006183 GTP biosynthesis P 5 9 14 55.55556 64.28571 5 9 14 55.55556 64.28571 2.857 0 0 0009147 pyrimidine nucleoside triphosphate metabolism P 0 0 0 0 0 5 9 18 55.55556 50 2.857 0 0 0046039 GTP metabolism P 0 0 0 0 0 5 9 14 55.55556 64.28571 2.857 0 0 0000072 M-phase specific microtubule process P 0 0 0 0 0 5 9 16 55.55556 56.25 2.857 0 0 0006007 glucose catabolism P 0 2 2 0 100 13 35 67 37.14286 52.23881 2.836 0 0 0006220 pyrimidine nucleotide metabolism P 0 4 4 0 100 8 18 34 44.44444 52.94118 2.829 0 0 0016192 vesicle-mediated transport P 9 23 36 39.13044 63.88889 47 176 274 26.70455 64.23357 2.818 0 0 0042157 lipoprotein metabolism P 0 0 1 0 0 6 12 22 50 54.54546 2.805 0 0 0006364 rRNA processing P 7 15 28 46.66667 53.57143 7 15 28 46.66667 53.57143 2.804 0 0 0006997 nuclear organization and biogenesis P 0 2 3 0 66.66666 26 86 226 30.23256 38.0531 2.804 0 0 0015980 energy derivation by oxidation of organic compounds P 0 3 3 0 100 27 91 151 29.67033 60.2649 2.746 0 0 0016052 carbohydrate catabolism P 0 0 0 0 0 16 47 87 34.04255 54.02299 2.741 0 0 0019320 hexose catabolism P 0 0 0 0 0 13 36 68 36.11111 52.94118 2.717 0 0 0006118 electron transport P 44 187 511 23.52941 36.59491 52 201 545 25.87065 36.88073 2.708 0 0 0016684 oxidoreductase activity\, acting on peroxide as acceptor F 0 0 0 0 0 9 22 48 40.90909 45.83333 2.702 0 0 0015405 P-P-bond-hydrolysis-driven transporter activity F 0 0 0 0 0 26 88 168 29.54545 52.38095 2.67 0 0 0006512 ubiquitin cycle P 16 47 114 34.04255 41.22807 17 52 128 32.69231 40.625 2.633 0 0 0006564 L-serine biosynthesis P 4 7 11 57.14286 63.63636 4 7 11 57.14286 63.63636 2.628 0 0 0019748 secondary metabolism P 0 0 0 0 0 4 7 9 57.14286 77.77778 2.628 0 0 0016864 intramolecular isomerase activity\, transposing S-S bonds F 0 0 0 0 0 4 7 8 57.14286 87.5 2.628 0 0 0005852 eukaryotic translation initiation factor 3 complex C 4 7 9 57.14286 77.77778 4 7 9 57.14286 77.77778 2.628 0 0 0003756 protein disulfide isomerase activity F 4 7 8 57.14286 87.5 4 7 8 57.14286 87.5 2.628 0 0 0006595 polyamine metabolism P 1 1 2 100 50 4 7 9 57.14286 77.77778 2.628 0 0 0005786 signal recognition particle C 4 7 10 57.14286 70 4 7 10 57.14286 70 2.628 0 0 0006462 protein complex assembly\, multichaperone pathway P 2 4 4 50 100 4 7 7 57.14286 100 2.628 0 0 0016194 nonselective vesicle exocytosis P 0 0 0 0 0 4 7 14 57.14286 50 2.628 0 0 0008094 DNA dependent ATPase activity F 3 8 20 37.5 40 7 16 44 43.75 36.36364 2.596 0 0 0005657 replication fork C 0 0 0 0 0 7 16 24 43.75 66.66666 2.596 0 0 0030554 adenyl nucleotide binding F 0 0 0 0 0 147 660 1548 22.27273 42.63566 2.584 0 0 0006417 regulation of protein biosynthesis P 6 12 18 50 66.66666 6 13 21 46.15385 61.90476 2.562 0 0 0008022 protein C-terminus binding F 6 13 18 46.15385 72.22222 6 13 18 46.15385 72.22222 2.562 0 0 0042158 lipoprotein biosynthesis P 0 0 0 0 0 5 10 19 50 52.63158 2.56 0 0 0009070 serine family amino acid biosynthesis P 0 0 0 0 0 5 10 16 50 62.5 2.56 0 0 0006497 protein lipidation P 0 0 0 0 0 5 10 19 50 52.63158 2.56 0 0 0008026 ATP dependent helicase activity F 12 46 121 26.08696 38.01653 20 65 161 30.76923 40.37267 2.545 0 0 0005524 ATP binding F 145 652 1535 22.23926 42.47557 145 652 1535 22.23926 42.47557 2.543 0 0 0016765 transferase activity\, transferring alkyl or aryl (other than methyl) groups F 0 0 0 0 0 12 34 55 35.29412 61.81818 2.517 0 0 0008283 cell proliferation P 23 162 239 14.19753 67.78242 133 596 1040 22.31544 57.30769 2.471 0 0 0000785 chromatin C 8 22 58 36.36364 37.93103 12 35 128 34.28571 27.34375 2.4 0 0 0003684 damaged DNA binding F 9 24 49 37.5 48.97959 9 24 49 37.5 48.97959 2.392 0 0 0019012 virion C 0 0 0 0 0 3 5 43 60 11.62791 2.385 0 0 0008042 iron-sulfur electron transfer carrier F 3 5 7 60 71.42857 3 5 7 60 71.42857 2.385 0 0 0046728 viral capsid (sensu Retroviridae) C 0 0 0 0 0 3 5 13 60 38.46154 2.385 0 0 0008320 protein carrier activity F 3 5 12 60 41.66667 3 5 12 60 41.66667 2.385 0 0 0019843 rRNA binding F 3 5 5 60 100 3 5 5 60 100 2.385 0 0 0016891 endoribonuclease activity\, producing 5’-phosphomonoesters F 0 0 0 0 0 3 5 21 60 23.80952 2.385 0 0 0000781 chromosome\, telomeric region C 3 5 10 60 50 3 5 11 60 45.45454 2.385 0 0 0000062 acyl-CoA binding F 3 5 10 60 50 3 5 10 60 50 2.385 0 0 0006476 protein amino acid deacetylation P 0 1 2 0 50 3 5 9 60 55.55556 2.385 0 0 0016780 phosphotransferase activity\, for other substituted phosphate groups F 0 0 0 0 0 3 5 5 60 100 2.385 0 0 0004407 histone deacetylase activity F 3 5 11 60 45.45454 3 5 11 60 45.45454 2.385 0 0 0005868 cytoplasmic dynein complex C 3 5 8 60 62.5 3 5 8 60 62.5 2.385 0 0 0016569 covalent chromatin modification P 0 0 0 0 0 3 5 8 60 62.5 2.385 0 0 0016570 histone modification P 0 0 0 0 0 3 5 8 60 62.5 2.385 0 0 0019013 viral nucleocapsid C 3 5 13 60 38.46154 3 5 13 60 38.46154 2.385 0 0 0019028 viral capsid C 0 0 28 0 0 3 5 41 60 12.19512 2.385 0 0 0006325 establishment and/or maintenance of chromatin architecture P 1 6 16 16.66667 37.5 19 63 192 30.15873 32.8125 2.38 0 0 0000074 regulation of cell cycle P 23 107 179 21.49533 59.77654 55 224 357 24.55357 62.7451 2.348 0 0 0006810 transport P 52 290 696 17.93103 41.66667 214 1009 2118 21.20912 47.63928 2.347 0 0 0004004 ATP dependent RNA helicase activity F 6 14 20 42.85714 70 6 14 20 42.85714 70 2.342 0 0 0005048 signal sequence binding F 1 3 4 33.33333 75 6 14 19 42.85714 73.68421 2.342 0 0 0015629 actin cytoskeleton C 13 56 90 23.21428 62.22222 32 120 227 26.66667 52.86344 2.306 0 0 0004659 prenyltransferase activity F 1 2 4 50 50 5 11 22 45.45454 50 2.297 0 0 0019887 protein kinase regulator activity F 0 0 0 0 0 5 11 22 45.45454 50 2.297 0 0 0016616 oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor F 2 4 7 50 57.14286 18 60 118 30 50.84746 2.291 0 0 0009209 pyrimidine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 4 8 12 50 66.66666 2.289 0 0 0006241 CTP biosynthesis P 4 8 12 50 66.66666 4 8 12 50 66.66666 2.289 0 0 0004550 nucleoside-diphosphate kinase activity F 4 8 12 50 66.66666 4 8 12 50 66.66666 2.289 0 0 0000723 telomere maintenance P 0 0 0 0 0 4 8 14 50 57.14286 2.289 0 0 0015035 protein disulfide oxidoreductase activity F 0 1 2 0 50 4 8 10 50 80 2.289 0 0 0046036 CTP metabolism P 0 0 0 0 0 4 8 12 50 66.66666 2.289 0 0 0006228 UTP biosynthesis P 4 8 12 50 66.66666 4 8 12 50 66.66666 2.289 0 0 0046051 UTP metabolism P 0 0 0 0 0 4 8 12 50 66.66666 2.289 0 0 0007040 lysosome organization and biogenesis P 1 2 3 50 66.66666 4 8 10 50 80 2.289 0 0 0009208 pyrimidine ribonucleoside triphosphate metabolism P 0 0 0 0 0 4 8 12 50 66.66666 2.289 0 0 0004003 ATP dependent DNA helicase activity F 4 8 24 50 33.33333 4 8 24 50 33.33333 2.289 0 0 0007004 telomerase-dependent telomere maintenance P 4 8 15 50 53.33333 4 8 15 50 53.33333 2.289 0 0 0003928 RAB small monomeric GTPase activity F 12 36 74 33.33333 48.64865 12 36 74 33.33333 48.64865 2.287 0 0 0005198 structural molecule activity F 21 108 276 19.44444 39.13044 83 361 810 22.99169 44.5679 2.228 0 0 0003746 translation elongation factor activity F 7 18 30 38.88889 60 7 18 32 38.88889 56.25 2.222 0 0 0019205 nucleobase\, nucleoside\, nucleotide kinase activity F 0 0 0 0 0 10 29 45 34.48276 64.44444 2.211 0 0 0016835 carbon-oxygen lyase activity F 0 0 0 0 0 12 37 60 32.43243 61.66667 2.178 0 0 0007582 physiological processes P 0 10 18 0 55.55556 991 5176 11583 19.14606 44.68618 2.156 0 0 0006887 exocytosis P 4 12 25 33.33333 48 8 22 43 36.36364 51.16279 2.152 0 0 0008168 methyltransferase activity F 9 23 44 39.13044 52.27273 19 66 154 28.78788 42.85714 2.149 0 0 0017069 snRNA binding F 0 0 0 0 0 2 3 3 66.66666 100 2.144 0 0 0030832 regulation of actin filament length P 0 0 1 0 0 2 3 5 66.66666 60 2.144 0 0 0008064 regulation of actin polymerization and/or depolymerization P 2 3 4 66.66666 75 2 3 4 66.66666 75 2.144 0 0 0003688 DNA replication origin binding F 2 3 4 66.66666 75 2 3 4 66.66666 75 2.144 0 0 0046112 nucleobase biosynthesis P 0 0 0 0 0 2 3 9 66.66666 33.33333 2.144 0 0 0015988 energy coupled proton transport\, against the electrochemical gradient P 2 3 4 66.66666 75 2 3 4 66.66666 75 2.144 0 0 0004449 isocitrate dehydrogenase (NAD) activity F 2 3 5 66.66666 60 2 3 5 66.66666 60 2.144 0 0 0015985 energy coupled proton transport\, down the electrochemical gradient P 0 0 0 0 0 2 3 7 66.66666 42.85714 2.144 0 0 0008333 endosome to lysosome transport P 2 3 4 66.66666 75 2 3 4 66.66666 75 2.144 0 0 0006611 protein-nucleus export P 2 3 3 66.66666 100 2 3 4 66.66666 75 2.144 0 0 0016878 acid-thiol ligase activity F 0 0 0 0 0 2 3 5 66.66666 60 2.144 0 0 0004470 malic enzyme activity F 0 0 1 0 0 2 3 4 66.66666 75 2.144 0 0 0008382 iron superoxide dismutase activity F 2 3 5 66.66666 60 2 3 5 66.66666 60 2.144 0 0 0008641 small protein activating enzyme activity F 0 0 0 0 0 2 3 7 66.66666 42.85714 2.144 0 0 0015482 voltage-dependent anion channel porin activity F 2 3 3 66.66666 100 2 3 3 66.66666 100 2.144 0 0 0005945 6-phosphofructokinase complex C 2 3 4 66.66666 75 2 3 4 66.66666 75 2.144 0 0 0008535 cytochrome c oxidase biogenesis P 2 3 3 66.66666 100 2 3 3 66.66666 100 2.144 0 0 0003872 6-phosphofructokinase activity F 2 3 4 66.66666 75 2 3 4 66.66666 75 2.144 0 0 0016954 nickel superoxide dismutase activity F 2 3 5 66.66666 60 2 3 5 66.66666 60 2.144 0 0 0016667 oxidoreductase activity\, acting on sulfur group of donors F 0 0 0 0 0 2 3 4 66.66666 75 2.144 0 0 0005658 alpha DNA polymerase\:primase complex C 2 3 3 66.66666 100 2 3 3 66.66666 100 2.144 0 0 0006356 regulation of transcription from Pol I promoter P 2 3 4 66.66666 75 2 3 4 66.66666 75 2.144 0 0 0004730 pseudouridylate synthase activity F 2 3 10 66.66666 30 2 3 10 66.66666 30 2.144 0 0 0003790 actin modulating activity F 2 3 5 66.66666 60 2 3 5 66.66666 60 2.144 0 0 0006108 malate metabolism P 2 3 3 66.66666 100 2 3 3 66.66666 100 2.144 0 0 0008538 proteasome activator activity F 2 3 6 66.66666 50 2 3 6 66.66666 50 2.144 0 0 0006505 GPI anchor metabolism P 0 0 0 0 0 2 3 5 66.66666 60 2.144 0 0 0015986 ATP synthesis coupled proton transport P 2 3 7 66.66666 42.85714 2 3 7 66.66666 42.85714 2.144 0 0 0006506 GPI anchor biosynthesis P 2 3 5 66.66666 60 2 3 5 66.66666 60 2.144 0 0 0000339 RNA cap binding F 2 3 5 66.66666 60 2 3 5 66.66666 60 2.144 0 0 0008537 proteasome activator complex C 2 3 6 66.66666 50 2 3 6 66.66666 50 2.144 0 0 0008171 O-methyltransferase activity F 0 1 2 0 50 2 3 10 66.66666 30 2.144 0 0 0017070 U6 snRNA binding F 2 3 3 66.66666 100 2 3 3 66.66666 100 2.144 0 0 0005095 GTPase inhibitor activity F 2 3 8 66.66666 37.5 2 3 8 66.66666 37.5 2.144 0 0 0004839 ubiquitin activating enzyme activity F 2 3 7 66.66666 42.85714 2 3 7 66.66666 42.85714 2.144 0 0 0008383 manganese superoxide dismutase activity F 2 3 5 66.66666 60 2 3 5 66.66666 60 2.144 0 0 0006695 cholesterol biosynthesis P 6 14 17 42.85714 82.35294 6 15 20 40 75 2.139 0 0 0015450 protein translocase activity F 6 15 21 40 71.42857 6 15 21 40 71.42857 2.139 0 0 0008186 RNA dependent ATPase activity F 0 1 1 0 100 6 15 21 40 71.42857 2.139 0 0 0000098 sulfur amino acid catabolism P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0004044 amidophosphoribosyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0003878 ATP citrate synthase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004643 phosphoribosylaminoimidazolecarboxamide formyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0003874 6-pyruvoyltetrahydropterin synthase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0007034 vacuolar transport P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004018 adenylosuccinate lyase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0009113 purine base biosynthesis P 1 1 3 100 33.33333 1 1 3 100 33.33333 2.095 0 0 0004582 dolichyl-phosphate beta-D-mannosyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0003937 IMP cyclohydrolase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0008628 induction of apoptosis by hormones P 1 1 4 100 25 1 1 4 100 25 2.095 0 0 0004588 orotate phosphoribosyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0006222 UMP biosynthesis P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004450 isocitrate dehydrogenase (NADP) activity F 1 1 4 100 25 1 1 4 100 25 2.095 0 0 0003977 UDP-N-acetylglucosamine diphosphorylase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0030516 regulation of axon extension P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0006042 glucosamine biosynthesis P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0030180 solute\:solute exchange P 0 0 2 0 0 1 1 3 100 33.33333 2.095 0 0 0015226 carnitine transporter activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0009087 methionine catabolism P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0006097 glyoxylate cycle P 1 1 3 100 33.33333 1 1 3 100 33.33333 2.095 0 0 0005278 acetylcholine\:hydrogen antiporter activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004768 stearoyl-CoA 9-desaturase activity F 1 1 4 100 25 1 1 4 100 25 2.095 0 0 0006424 glutamyl-tRNA aminoacylation P 1 1 6 100 16.66667 1 1 6 100 16.66667 2.095 0 0 0004818 glutamate-tRNA ligase activity F 1 1 6 100 16.66667 1 1 6 100 16.66667 2.095 0 0 0046349 amino sugar biosynthesis P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0015008 ubiquinol-cytochrome-c reductase complex (sensu Eukarya) C 1 1 5 100 20 1 1 5 100 20 2.095 0 0 0008073 ornithine decarboxylase inhibitor activity F 1 1 4 100 25 1 1 4 100 25 2.095 0 0 0000036 acyl carrier activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0009200 deoxyribonucleoside triphosphate metabolism P 0 0 0 0 0 1 1 6 100 16.66667 2.095 0 0 0045267 proton-transporting ATP synthase\, catalytic core C 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0004671 protein-S-isoprenylcysteine O-methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004590 orotidine-5’-phosphate decarboxylase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004487 methylenetetrahydrofolate dehydrogenase (NAD) activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0016768 spermine synthase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0006515 misfolded or incompletely synthesized protein catabolism P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0004148 dihydrolipoamide dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0009211 pyrimidine deoxyribonucleoside triphosphate metabolism P 0 0 0 0 0 1 1 6 100 16.66667 2.095 0 0 0047598 7-dehydrocholesterol reductase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0000275 proton-transporting ATP synthase complex\, catalytic core F(1) (sensu Eukarya) C 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0016725 oxidoreductase activity\, acting on CH2 groups F 0 0 0 0 0 1 1 4 100 25 2.095 0 0 0016728 oxidoreductase activity\, acting on CH2 groups\, disulfide as acceptor F 0 0 0 0 0 1 1 4 100 25 2.095 0 0 0018196 peptidyl-asparagine modification P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0015870 acetylcholine transport P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0045261 proton-transporting ATP synthase complex\, catalytic core F(1) C 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0019145 aminobutyraldehyde dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0005784 translocon C 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0046073 dTMP metabolism P 0 0 0 0 0 1 1 3 100 33.33333 2.095 0 0 0006894 Golgi to secretory vesicle transport P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0007255 activation of MAP/ERK kinase kinase P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004581 dolichyl-phosphate beta-glucosyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004852 uroporphyrinogen-III synthase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0008424 glycoprotein 6-alpha-L-fucosyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0030433 ER-associated protein catabolism P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004616 phosphogluconate dehydrogenase (decarboxylating) activity F 1 1 4 100 25 1 1 4 100 25 2.095 0 0 0009176 pyrimidine deoxyribonucleoside monophosphate metabolism P 0 0 0 0 0 1 1 3 100 33.33333 2.095 0 0 0009263 deoxyribonucleotide biosynthesis P 0 0 0 0 0 1 1 4 100 25 2.095 0 0 0009221 pyrimidine deoxyribonucleotide biosynthesis P 0 0 0 0 0 1 1 4 100 25 2.095 0 0 0009162 deoxyribonucleoside monophosphate metabolism P 0 0 0 0 0 1 1 3 100 33.33333 2.095 0 0 0004337 geranyltranstransferase activity F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0005047 signal recognition particle binding F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0018279 N-linked glycosylation via asparagine P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0008309 double-stranded DNA specific exodeoxyribonuclease activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004731 purine-nucleoside phosphorylase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004618 phosphoglycerate kinase activity F 1 1 3 100 33.33333 1 1 3 100 33.33333 2.095 0 0 0007252 I-kappaB phosphorylation P 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0009177 pyrimidine deoxyribonucleoside monophosphate biosynthesis P 0 0 0 0 0 1 1 3 100 33.33333 2.095 0 0 0000790 nuclear chromatin C 0 0 0 0 0 1 1 4 100 25 2.095 0 0 0000792 heterochromatin C 0 0 0 0 0 1 1 4 100 25 2.095 0 0 0030337 DNA polymerase processivity factor activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004357 glutamate-cysteine ligase activity F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0005785 signal recognition particle receptor complex C 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0008709 7-alpha-hydroxysteroid dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0015721 bile acid transport P 1 1 2 100 50 1 1 3 100 33.33333 2.095 0 0 0008785 alkyl hydroperoxide reductase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0042979 ornithine decarboxylase regulator activity F 0 0 0 0 0 1 1 4 100 25 2.095 0 0 0004348 glucosylceramidase activity F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0004178 leucyl aminopeptidase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004370 glycerol kinase activity F 1 1 3 100 33.33333 1 1 3 100 33.33333 2.095 0 0 0016224 non-selenium glutathione peroxidase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0008464 gamma-glutamyl hydrolase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0016804 prolyl aminopeptidase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0008025 diazepam-binding inhibitor activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0045343 regulation of MHC class I biosynthesis P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0045103 intermediate filament-based process P 0 0 0 0 0 1 1 3 100 33.33333 2.095 0 0 0016668 oxidoreductase activity\, acting on sulfur group of donors\, NAD or NADP as acceptor F 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0015283 apoptogenic cytochrome c release channel activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0030181 sodium\:calcium exchange P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0000150 recombinase activity F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0015853 adenine transport P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0005107 GPI-linked ephrin F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004127 cytidylate kinase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0003785 actin monomer binding F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0046597 negative regulation of virion penetration P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0008214 protein amino acid dealkylation P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0006200 ATP catabolism P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0006545 glycine biosynthesis P 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0004146 dihydrofolate reductase activity F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0042083 5\,10-methylenetetrahydrofolate-dependent methyltransferase activity F 0 0 0 0 0 1 1 3 100 33.33333 2.095 0 0 0009346 citrate lyase complex C 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0006481 C-terminal protein amino acid methylation P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004170 dUTP diphosphatase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0046080 dUTP metabolism P 1 1 5 100 20 1 1 5 100 20 2.095 0 0 0045815 positive regulation of gene expression\, epigenetic P 0 0 0 0 0 1 1 2 100 50 2.095 0 0 0045089 positive regulation of innate immune response P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0009051 pentose-phosphate shunt\, oxidative branch P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity F 1 1 4 100 25 1 1 4 100 25 2.095 0 0 0050694 galactose 3-O-sulfotransferase activity F 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0004310 farnesyl-diphosphate farnesyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004419 hydroxymethylglutaryl-CoA lyase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0009157 deoxyribonucleoside monophosphate biosynthesis P 1 0 1 0 0 1 1 3 100 33.33333 2.095 0 0 0008617 guanosine metabolism P 1 1 1 100 100 1 1 3 100 33.33333 2.095 0 0 0015879 carnitine transport P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004776 succinate-CoA ligase (GDP-forming) activity F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0047429 nucleoside-triphosphate diphosphatase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity F 1 1 4 100 25 1 1 4 100 25 2.095 0 0 0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004619 phosphoglycerate mutase activity F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0003826 alpha-ketoacid dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004905 interferon-alpha/beta receptor activity F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0016656 monodehydroascorbate reductase (NADH) activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004427 inorganic diphosphatase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0016314 phosphatidylinositol-3\,4\,5-trisphosphate 3-phosphatase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0045213 neurotransmitter receptor metabolism P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0017053 transcriptional repressor complex C 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0006465 signal peptide processing P 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0046487 glyoxylate metabolism P 0 0 0 0 0 1 1 3 100 33.33333 2.095 0 0 0003929 RAN small monomeric GTPase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004215 cathepsin H activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0005971 ribonucleoside-diphosphate reductase complex C 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004748 ribonucleoside-diphosphate reductase activity F 1 1 4 100 25 1 1 4 100 25 2.095 0 0 0004471 malate dehydrogenase (decarboxylating) activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0008097 5S rRNA binding F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0008750 NAD(P) transhydrogenase (AB-specific) activity F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0018410 peptide/protein carboxyl-terminal blocking P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0000104 succinate dehydrogenase activity F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0004138 deoxyguanosine kinase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004523 ribonuclease H activity F 1 1 9 100 11.11111 1 1 10 100 10 2.095 0 0 0030530 heterogeneous nuclear ribonucleoprotein complex C 1 1 3 100 33.33333 1 1 3 100 33.33333 2.095 0 0 0016193 nonselective vesicle endocytosis P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0000172 ribonuclease MRP complex C 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0008609 alkylglycerone-phosphate synthase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0005277 acetylcholine transporter activity F 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0007094 mitotic spindle checkpoint P 1 1 4 100 25 1 1 4 100 25 2.095 0 0 0030517 negative regulation of axon extension P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0019987 negative regulation of anti-apoptosis P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0045104 intermediate filament cytoskeleton organization and biogenesis P 1 1 3 100 33.33333 1 1 3 100 33.33333 2.095 0 0 0045736 negative regulation of CDK activity P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0006482 protein amino acid demethylation P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0001509 legumain activity F 1 1 5 100 20 1 1 5 100 20 2.095 0 0 0001508 regulation of action potential P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0030267 glyoxylate reductase (NADP) activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0016833 oxo-acid-lyase activity F 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0008490 arsenite porter activity F 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0015104 antimonite transporter activity F 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0042960 antimonite porter activity F 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0030349 syntaxin-13 binding F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0008296 3’-5’ exodeoxyribonuclease activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0006048 UDP-N-acetylglucosamine biosynthesis P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0006345 loss of chromatin silencing P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0019059 initiation of viral infection P 0 0 0 0 0 1 1 2 100 50 2.095 0 0 0009207 purine ribonucleoside triphosphate catabolism P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0005649 transportin C 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0030175 filopodium C 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0030275 LRR-domain binding F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0008046 axon guidance receptor activity F 1 1 1 100 100 1 1 2 100 50 2.095 0 0 0005720 nuclear heterochromatin C 1 1 3 100 33.33333 1 1 4 100 25 2.095 0 0 0009146 purine nucleoside triphosphate catabolism P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0004183 carboxypeptidase E activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0016215 CoA desaturase activity F 0 0 0 0 0 1 1 4 100 25 2.095 0 0 0005793 ER-Golgi intermediate compartment C 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0005682 snRNP U5 C 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0008576 vesicle-fusing ATPase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0047290 (alpha-N-acetylneuraminyl-2\,3-alpha-galactosyl-1\,3)-N-acetyl-galactosaminide alpha-2\,6-sialyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0005754 proton-transporting ATP synthase\, catalytic core (sensu Eukarya) C 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0006398 histone mRNA 3’-end processing P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0046933 hydrogen-transporting ATP synthase activity\, rotational mechanism F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004001 adenosine kinase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0008280 cohesin core heterodimer C 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0007064 mitotic sister chromatid cohesion P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0005672 transcription factor TFIIA complex C 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0015130 mevalonate transporter activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0016619 malate dehydrogenase (oxaloacetate-decarboxylating) activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0009387 DNA supercoiling activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0007022 chaperonin-mediated tubulin folding P 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0019008 molybdopterin synthase complex C 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0009493 adrenodoxin-type ferredoxin F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0006608 snRNP protein-nucleus import P 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0001510 RNA methylation P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0042961 antimonite-transporting ATPase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0015446 arsenite-transporting ATPase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004610 phosphoacetylglucosamine mutase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0016422 mRNA (2’-O-methyladenosine-N6-)-methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0006902 nonselective vesicle assembly P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0030519 snoRNP binding F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0015728 mevalonate transport P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0005173 stem cell factor receptor binding F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0045285 ubiquinol-cytochrome-c reductase complex C 0 0 4 0 0 1 1 9 100 11.11111 2.095 0 0 0046718 viral entry P 0 0 1 0 0 1 1 2 100 50 2.095 0 0 0019063 virion penetration P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0046596 regulation of virion penetration P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0045088 regulation of innate immune response P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0045341 MHC class I biosynthesis P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0007006 mitochondrial membrane organization and biogenesis P 1 1 1 100 100 1 1 2 100 50 2.095 0 0 0019962 interferon-alpha/beta binding F 0 0 0 0 0 1 1 2 100 50 2.095 0 0 0016774 phosphotransferase activity\, carboxyl group as acceptor F 0 0 0 0 0 1 1 3 100 33.33333 2.095 0 0 0004327 formaldehyde dehydrogenase (glutathione) activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004648 phosphoserine transaminase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0006781 succinyl-CoA pathway P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004617 phosphoglycerate dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0045545 syndecan binding F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0030060 L-malate dehydrogenase activity F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0008549 dynamine GTPase activity F 1 1 4 100 25 1 1 4 100 25 2.095 0 0 0019144 ADP-sugar diphosphatase activity F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0008093 cytoskeletal adaptor activity F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0030100 regulation of endocytosis P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0000145 exocyst C 1 1 3 100 33.33333 1 1 3 100 33.33333 2.095 0 0 0019303 D-ribose catabolism P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0017072 tubulin-specific chaperone activity F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0006393 RNA transcription termination from mitochondrial promoter P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004775 succinate-CoA ligase (ADP-forming) activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0030172 troponin C binding F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0006144 purine base metabolism P 0 0 1 0 0 1 1 4 100 25 2.095 0 0 0019323 pentose catabolism P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0046921 alpha(1\,6)-fucosyltransferase activity F 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0006863 purine transport P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0004820 glycine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0008180 signalosome complex C 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0004807 triose-phosphate isomerase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0016838 carbon-oxygen lyase activity\, acting on phosphates F 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0006426 glycyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004102 choline O-acetyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0003980 UDP-glucose\:glycoprotein glucosyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0030150 mitochondrial matrix protein import P 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0007095 mitotic G2 checkpoint P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0006433 prolyl-tRNA aminoacylation P 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0004743 pyruvate kinase activity F 1 1 5 100 20 1 1 5 100 20 2.095 0 0 0006437 tyrosyl-tRNA aminoacylation P 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0004827 proline-tRNA ligase activity F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0008781 N-acylneuraminate cytidylyltransferase activity F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0043021 ribonucleoprotein binding F 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0003957 NAD(P) transhydrogenase (B-specific) activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004831 tyrosine-tRNA ligase activity F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0001733 galactosylceramide sulfotransferase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0008398 sterol 14-demethylase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0030425 dendrite C 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0004757 sepiapterin reductase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0016359 mitotic sister chromatid separation P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0008119 thiopurine S-methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0019852 L-ascorbic acid metabolism P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0006014 D-ribose metabolism P 0 0 1 0 0 1 1 2 100 50 2.095 0 0 0009203 ribonucleoside triphosphate catabolism P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0005377 intracellular copper ion transporter F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0008482 sulfite oxidase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0016781 phosphotransferase activity\, paired acceptors F 0 0 0 0 0 1 1 3 100 33.33333 2.095 0 0 0003788 actin monomer sequestering activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0004139 deoxyribose-phosphate aldolase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0006045 N-acetylglucosamine biosynthesis P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0009174 pyrimidine ribonucleoside monophosphate biosynthesis P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0003964 RNA-directed DNA polymerase activity F 1 1 32 100 3.125 1 1 34 100 2.941176 2.095 0 0 0009143 nucleoside triphosphate catabolism P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0046049 UMP metabolism P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0006278 RNA dependent DNA replication P 1 1 31 100 3.225806 1 1 31 100 3.225806 2.095 0 0 0004799 thymidylate synthase activity F 1 1 3 100 33.33333 1 1 3 100 33.33333 2.095 0 0 0015266 protein channel activity F 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0009173 pyrimidine ribonucleoside monophosphate metabolism P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0008262 importin-alpha export receptor activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0016461 unconventional myosin C 1 1 4 100 25 1 1 4 100 25 2.095 0 0 0004321 fatty-acyl-CoA synthase activity F 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0019321 pentose metabolism P 0 0 0 0 0 1 1 2 100 50 2.095 0 0 0015993 molecular hydrogen transport P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0016358 dendrite morphogenesis P 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0005689 minor (U12-dependent) spliceosome complex C 0 0 0 0 0 1 1 2 100 50 2.095 0 0 0004756 selenide\, water dikinase activity F 1 1 3 100 33.33333 1 1 3 100 33.33333 2.095 0 0 0006231 dTMP biosynthesis P 1 1 3 100 33.33333 1 1 3 100 33.33333 2.095 0 0 0006207 ’de novo’ pyrimidine base biosynthesis P 1 1 5 100 20 1 1 5 100 20 2.095 0 0 0045212 neurotransmitter receptor biosynthesis P 1 1 1 100 100 1 1 1 100 100 2.095 0 0 0015851 nucleobase transport P 0 0 0 0 0 1 1 1 100 100 2.095 0 0 0004311 farnesyltranstransferase activity F 0 0 1 0 0 1 1 3 100 33.33333 2.095 0 0 0004586 ornithine decarboxylase activity F 1 1 2 100 50 1 1 2 100 50 2.095 0 0 0004386 helicase activity F 1 8 21 12.5 38.09524 20 71 179 28.16901 39.66481 2.095 0 0 0000086 G2/M transition of mitotic cell cycle P 1 2 6 50 33.33333 10 30 44 33.33333 68.18182 2.087 0 0 0048193 Golgi vesicle transport P 0 0 0 0 0 11 34 54 32.35294 62.96296 2.075 0 0 0030286 dynein complex C 1 6 21 16.66667 28.57143 5 12 38 41.66667 31.57895 2.061 0 0 0006270 DNA replication initiation P 5 12 22 41.66667 54.54546 5 12 22 41.66667 54.54546 2.061 0 0 0000151 ubiquitin ligase complex C 4 10 26 40 38.46154 5 12 31 41.66667 38.70968 2.061 0 0 0030261 chromosome condensation P 0 0 0 0 0 5 12 13 41.66667 92.30769 2.061 0 0 0015630 microtubule cytoskeleton C 2 6 6 33.33333 100 24 89 206 26.96629 43.20388 2.055 0 0 0016614 oxidoreductase activity\, acting on CH-OH group of donors F 0 1 3 0 33.33333 18 63 122 28.57143 51.63934 2.055 0 0 0006323 DNA packaging P 1 9 11 11.11111 81.81818 20 72 201 27.77778 35.8209 2.024 0 0 0003682 chromatin binding F 6 21 48 28.57143 43.75 8 23 52 34.78261 44.23077 2.006 0 0 0008654 phospholipid biosynthesis P 6 16 24 37.5 66.66666 8 23 36 34.78261 63.88889 2.006 0 0 0005217 intracellular ligand-gated ion channel activity F 0 0 0 0 0 4 9 12 44.44444 75 1.999 0 0 0019438 aromatic compound biosynthesis P 0 0 0 0 0 4 9 16 44.44444 56.25 1.999 0 0 0005795 Golgi stack C 3 7 13 42.85714 53.84615 4 9 17 44.44444 52.94118 1.999 0 0 0007093 mitotic checkpoint P 2 7 8 28.57143 87.5 4 9 13 44.44444 69.23077 1.999 0 0 0008276 protein methyltransferase activity F 0 1 1 0 100 4 9 16 44.44444 56.25 1.999 0 0 0016408 C-acyltransferase activity F 0 0 0 0 0 4 9 9 44.44444 100 1.999 0 0 0042559 pteridine and derivative biosynthesis P 0 0 0 0 0 4 9 16 44.44444 56.25 1.999 0 0 0042558 pteridine and derivative metabolism P 0 0 0 0 0 4 9 16 44.44444 56.25 1.999 0 0 0009060 aerobic respiration P 3 6 9 50 66.66666 3 6 9 50 66.66666 1.982 0 0 0005092 GDP-dissociation inhibitor activity F 1 1 1 100 100 3 6 6 50 100 1.982 0 0 0030176 integral to endoplasmic reticulum membrane C 3 6 9 50 66.66666 3 6 9 50 66.66666 1.982 0 0 0004029 aldehyde dehydrogenase (NAD) activity F 3 6 8 50 75 3 6 8 50 75 1.982 0 0 0005527 macrolide binding F 0 0 0 0 0 3 6 8 50 75 1.982 0 0 0003711 transcriptional elongation regulator activity F 2 4 7 50 57.14286 3 6 10 50 60 1.982 0 0 0005881 cytoplasmic microtubule C 0 1 1 0 100 3 6 9 50 66.66666 1.982 0 0 0004859 phospholipase inhibitor activity F 3 4 5 75 80 3 6 8 50 75 1.982 0 0 0045333 cellular respiration P 0 0 1 0 0 3 6 10 50 60 1.982 0 0 0005698 centromere C 3 6 6 50 100 3 6 6 50 100 1.982 0 0 0016288 cytokinesis P 3 6 7 50 85.71429 3 6 7 50 85.71429 1.982 0 0 0006596 polyamine biosynthesis P 3 3 4 100 75 3 6 7 50 85.71429 1.982 0 0 0004300 enoyl-CoA hydratase activity F 3 6 6 50 100 3 6 6 50 100 1.982 0 0 0005528 FK506 binding F 3 6 8 50 75 3 6 8 50 75 1.982 0 0 0007021 tubulin folding P 1 1 1 100 100 3 6 7 50 85.71429 1.982 0 0 0000793 condensed chromosome C 0 0 0 0 0 3 6 7 50 85.71429 1.982 0 0 0019213 deacetylase activity F 0 0 0 0 0 3 6 14 50 42.85714 1.982 0 0 0005938 cell cortex C 0 0 0 0 0 3 6 13 50 46.15385 1.982 0 0 0006903 nonselective vesicle targeting P 3 6 7 50 85.71429 3 6 7 50 85.71429 1.982 0 0 0016652 oxidoreductase activity\, acting on NADH or NADPH\, NAD or NADP as acceptor F 0 0 0 0 0 3 6 9 50 66.66666 1.982 0 0 0007076 mitotic chromosome condensation P 3 6 7 50 85.71429 3 6 7 50 85.71429 1.982 0 0 0004689 phosphorylase kinase activity F 0 1 2 0 50 3 6 7 50 85.71429 1.982 0 0 0000088 mitotic prophase P 0 0 0 0 0 3 6 7 50 85.71429 1.982 0 0 0016820 hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances F 0 0 0 0 0 20 73 147 27.39726 49.65986 1.954 0 0 0042626 ATPase activity\, coupled to transmembrane movement of substances F 0 0 0 0 0 20 73 147 27.39726 49.65986 1.954 0 0 0003931 Rho small monomeric GTPase activity F 6 16 37 37.5 43.24324 6 16 37 37.5 43.24324 1.952 0 0 0005856 cytoskeleton C 28 150 247 18.66667 60.72874 77 342 697 22.51462 49.06743 1.933 0 0 0016741 transferase activity\, transferring one-carbon groups F 0 0 0 0 0 19 69 159 27.53623 43.39622 1.929 0 0 0006899 nonselective vesicle transport P 14 48 61 29.16667 78.68852 14 48 61 29.16667 78.68852 1.898 0 0 0000075 cell cycle checkpoint P 3 7 11 42.85714 63.63636 8 24 34 33.33333 70.58823 1.866 0 0 0000079 regulation of CDK activity P 8 27 37 29.62963 72.97298 9 28 38 32.14286 73.68421 1.854 0 0 0006633 fatty acid biosynthesis P 8 15 27 53.33333 55.55556 9 28 44 32.14286 63.63636 1.854 0 0 0005819 spindle C 3 8 11 37.5 72.72727 9 28 40 32.14286 70 1.854 0 0 0007050 cell cycle arrest P 10 32 55 31.25 58.18182 10 32 55 31.25 58.18182 1.852 0 0 0042625 ATPase activity\, coupled to transmembrane movement of ions F 0 0 0 0 0 10 32 58 31.25 55.17241 1.852 0 0 0016853 isomerase activity F 16 57 96 28.07018 59.375 18 66 122 27.27273 54.09836 1.831 0 0 0030036 actin cytoskeleton organization and biogenesis P 10 30 40 33.33333 75 13 45 59 28.88889 76.27119 1.789 0 0 0030029 actin filament-based process P 0 0 0 0 0 13 45 59 28.88889 76.27119 1.789 0 0 0016821 hydrolase activity\, acting on acid anhydrides\, involved in cellular and subcellular movement F 0 0 0 0 0 6 17 36 35.29412 47.22222 1.778 0 0 0007088 regulation of mitosis P 2 5 8 40 62.5 6 17 25 35.29412 68 1.778 0 0 0006334 nucleosome assembly P 6 15 78 40 19.23077 6 17 80 35.29412 21.25 1.778 0 0 0006892 post-Golgi transport P 3 8 8 37.5 100 4 10 13 40 76.92308 1.746 0 0 0006298 mismatch repair P 4 10 28 40 35.71429 4 10 28 40 35.71429 1.746 0 0 0019206 nucleoside kinase activity F 0 0 0 0 0 4 10 16 40 62.5 1.746 0 0 0045005 maintenance of fidelity during DNA dependent DNA replication P 0 0 0 0 0 4 10 28 40 35.71429 1.746 0 0 0006888 ER to Golgi transport P 4 10 20 40 50 4 10 20 40 50 1.746 0 0 0008144 drug binding F 1 2 3 50 66.66666 4 10 15 40 66.66666 1.746 0 0 0004843 ubiquitin-specific protease activity F 4 10 14 40 71.42857 4 10 15 40 66.66666 1.746 0 0 0000090 mitotic anaphase P 0 3 3 0 100 4 10 12 40 83.33334 1.746 0 0 0006100 TCA intermediate metabolism P 0 0 0 0 0 4 10 12 40 83.33334 1.746 0 0 0005744 mitochondrial inner membrane pre-sequence translocase complex C 4 10 13 40 76.92308 4 10 13 40 76.92308 1.746 0 0 0003690 double-stranded DNA binding F 4 10 16 40 62.5 4 10 16 40 62.5 1.746 0 0 0006563 L-serine metabolism P 0 2 5 0 40 4 10 18 40 55.55556 1.746 0 0 0016776 phosphotransferase activity\, phosphate group as acceptor F 1 1 1 100 100 7 21 31 33.33333 67.74194 1.745 0 0 0003899 DNA-directed RNA polymerase activity F 6 19 34 31.57895 55.88235 7 21 36 33.33333 58.33333 1.745 0 0 0016886 ligase activity\, forming phosphoric ester bonds F 0 0 0 0 0 10 33 86 30.30303 38.37209 1.741 0 0 0006418 amino acid activation P 2 5 24 40 20.83333 8 25 75 32 33.33333 1.733 0 0 0008610 lipid biosynthesis P 2 6 6 33.33333 100 27 109 168 24.77064 64.88095 1.683 0 0 0004602 glutathione peroxidase activity F 2 6 9 33.33333 66.66666 3 7 10 42.85714 70 1.655 0 0 0009451 RNA modification P 0 0 1 0 0 3 7 13 42.85714 53.84615 1.655 0 0 0008139 nuclear localization sequence binding F 3 7 8 42.85714 87.5 3 7 8 42.85714 87.5 1.655 0 0 0004364 glutathione transferase activity F 5 14 21 35.71429 66.66666 5 14 21 35.71429 66.66666 1.653 0 0 0006626 protein-mitochondrial targeting P 0 1 1 0 100 5 14 19 35.71429 73.68421 1.653 0 0 0016836 hydro-lyase activity F 0 0 2 0 0 10 34 55 29.41176 61.81818 1.633 0 0 0005381 iron ion transporter activity F 2 3 3 66.66666 100 2 4 4 50 100 1.618 0 0 0015936 coenzyme A metabolism P 1 1 1 100 100 2 4 5 50 80 1.618 0 0 0007041 lysosomal transport P 0 1 1 0 100 2 4 5 50 80 1.618 0 0 0006268 DNA unwinding P 2 4 5 50 80 2 4 5 50 80 1.618 0 0 0008308 voltage-dependent ion-selective channel activity F 2 4 8 50 50 2 4 8 50 50 1.618 0 0 0016405 CoA-ligase activity F 0 1 2 0 50 2 4 7 50 57.14286 1.618 0 0 0019238 cyclohydrolase activity F 0 0 0 0 0 2 4 5 50 80 1.618 0 0 0008213 protein amino acid alkylation P 0 0 0 0 0 2 4 5 50 80 1.618 0 0 0000272 polysaccharide catabolism P 0 0 0 0 0 2 4 5 50 80 1.618 0 0 0016228 aldolase activity F 0 0 2 0 0 2 4 7 50 57.14286 1.618 0 0 0009112 nucleobase metabolism P 0 0 0 0 0 2 4 11 50 36.36364 1.618 0 0 0008536 RAN protein binding F 2 4 6 50 66.66666 2 4 6 50 66.66666 1.618 0 0 0000018 regulation of DNA recombination P 1 2 3 50 66.66666 2 4 5 50 80 1.618 0 0 0019720 Mo-molybdopterin cofactor metabolism P 0 0 0 0 0 2 4 11 50 36.36364 1.618 0 0 0005662 DNA replication factor A complex C 2 4 4 50 100 2 4 4 50 100 1.618 0 0 0009068 aspartate family amino acid catabolism P 0 0 0 0 0 2 4 5 50 80 1.618 0 0 0005639 integral to nuclear inner membrane C 2 4 4 50 100 2 4 4 50 100 1.618 0 0 0005980 glycogen catabolism P 2 4 4 50 100 2 4 4 50 100 1.618 0 0 0006479 protein amino acid methylation P 1 3 4 33.33333 75 2 4 5 50 80 1.618 0 0 0006777 Mo-molybdopterin cofactor biosynthesis P 2 4 11 50 36.36364 2 4 11 50 36.36364 1.618 0 0 0016721 oxidoreductase activity\, acting on superoxide radicals as acceptor F 0 0 0 0 0 2 4 7 50 57.14286 1.618 0 0 0009251 glucan catabolism P 0 0 0 0 0 2 4 5 50 80 1.618 0 0 0017040 ceramidase activity F 1 1 1 100 100 2 4 5 50 80 1.618 0 0 0006542 glutamine biosynthesis P 1 1 1 100 100 2 4 11 50 36.36364 1.618 0 0 0008430 selenium binding F 2 4 6 50 66.66666 2 4 6 50 66.66666 1.618 0 0 0016654 oxidoreductase activity\, acting on NADH or NADPH\, disulfide as acceptor F 0 0 0 0 0 2 4 5 50 80 1.618 0 0 0004128 cytochrome-b5 reductase activity F 2 4 5 50 80 2 4 5 50 80 1.618 0 0 0004784 superoxide dismutase activity F 0 0 0 0 0 2 4 7 50 57.14286 1.618 0 0 0016044 membrane organization and biogenesis P 0 1 1 0 100 2 4 8 50 50 1.618 0 0 0004402 histone acetyltransferase activity F 1 2 6 50 33.33333 2 4 8 50 50 1.618 0 0 0004685 calcium/calmodulin-dependent protein kinase activity F 2 4 8 50 50 2 4 8 50 50 1.618 0 0 0004785 copper\, zinc superoxide dismutase activity F 2 4 7 50 57.14286 2 4 7 50 57.14286 1.618 0 0 0005253 anion channel activity F 0 1 1 0 100 9 30 45 30 66.66666 1.616 0 0 0016126 sterol biosynthesis P 0 3 4 0 75 6 18 27 33.33333 66.66666 1.615 0 0 0007005 mitochondrion organization and biogenesis P 0 1 1 0 100 6 18 24 33.33333 75 1.615 0 0 0016071 mRNA metabolism P 1 2 6 50 33.33333 6 18 25 33.33333 72 1.615 0 0 0008452 RNA ligase activity F 0 0 0 0 0 8 26 75 30.76923 34.66667 1.605 0 0 0016875 ligase activity\, forming carbon-oxygen bonds F 0 0 0 0 0 8 26 75 30.76923 34.66667 1.605 0 0 0016876 ligase activity\, forming aminoacyl-tRNA and related compounds F 0 0 0 0 0 8 26 75 30.76923 34.66667 1.605 0 0 0004812 tRNA ligase activity F 2 6 23 33.33333 26.08696 8 26 75 30.76923 34.66667 1.605 0 0 0019867 outer membrane C 4 9 14 44.44444 64.28571 7 22 47 31.81818 46.80851 1.603 0 0 0016860 intramolecular isomerase activity F 0 0 0 0 0 7 22 37 31.81818 59.45946 1.603 0 0 0006139 nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism P 7 23 29 30.43478 79.31035 273 1363 2975 20.02935 45.81512 1.563 0 0 0016568 chromatin modification P 5 18 40 27.77778 45 10 35 73 28.57143 47.94521 1.529 0 0 0005667 transcription factor complex C 3 15 25 20 60 13 48 68 27.08333 70.58823 1.526 0 0 0009116 nucleoside metabolism P 3 8 15 37.5 53.33333 4 11 21 36.36364 52.38095 1.521 0 0 0006628 mitochondrial translocation P 4 11 15 36.36364 73.33334 4 11 15 36.36364 73.33334 1.521 0 0 0005665 DNA-directed RNA polymerase II\, core complex C 4 11 19 36.36364 57.89474 4 11 19 36.36364 57.89474 1.521 0 0 0015662 ATPase activity\, coupled to transmembrane movement of ions\, phosphorylative mechanism F 0 2 6 0 33.33333 9 31 57 29.03226 54.38596 1.504 0 0 0042027 cyclophilin-type peptidyl-prolyl cis-trans isomerase activity F 5 15 29 33.33333 51.72414 5 15 29 33.33333 51.72414 1.474 0 0 0016763 transferase activity\, transferring pentosyl groups F 0 0 0 0 0 5 15 29 33.33333 51.72414 1.474 0 0 0005875 microtubule associated complex C 7 30 63 23.33333 47.61905 13 49 117 26.53061 41.88034 1.442 0 0 0016591 DNA-directed RNA polymerase II\, holoenzyme C 0 0 0 0 0 10 36 54 27.77778 66.66666 1.428 0 0 0000775 chromosome\, pericentric region C 1 6 8 16.66667 75 3 8 10 37.5 80 1.379 0 0 0046983 protein dimerization activity F 0 0 0 0 0 3 8 11 37.5 72.72727 1.379 0 0 0008173 RNA methyltransferase activity F 1 2 4 50 50 3 8 15 37.5 53.33333 1.379 0 0 0016868 intramolecular transferase activity\, phosphotransferases F 1 2 6 50 33.33333 3 8 15 37.5 53.33333 1.379 0 0 0009123 nucleoside monophosphate metabolism P 0 0 0 0 0 3 8 22 37.5 36.36364 1.379 0 0 0007020 microtubule nucleation P 0 2 4 0 50 3 8 11 37.5 72.72727 1.379 0 0 0008435 anticoagulant activity F 3 8 9 37.5 88.88889 3 8 9 37.5 88.88889 1.379 0 0 0009124 nucleoside monophosphate biosynthesis P 0 0 0 0 0 3 8 22 37.5 36.36364 1.379 0 0 0006644 phospholipid metabolism P 1 10 13 10 76.92308 11 41 67 26.82927 61.19403 1.367 0 0 0006875 metal ion homeostasis P 1 3 3 33.33333 100 8 28 44 28.57143 63.63636 1.366 0 0 0006006 glucose metabolism P 1 10 13 10 76.92308 13 50 90 26 55.55556 1.36 0 0 0030005 di-\, tri-valent inorganic cation homeostasis P 0 0 0 0 0 7 24 40 29.16667 60 1.34 0 0 0003773 heat shock protein activity F 7 24 43 29.16667 55.81395 7 24 43 29.16667 55.81395 1.34 0 0 0008652 amino acid biosynthesis P 0 2 3 0 66.66666 7 24 47 29.16667 51.06383 1.34 0 0 0008624 induction of apoptosis by extracellular signals P 4 14 21 28.57143 66.66666 6 20 33 30 60.60606 1.319 0 0 0006414 translational elongation P 6 20 37 30 54.05405 6 20 39 30 51.28205 1.319 0 0 0005834 heterotrimeric G-protein complex C 6 20 42 30 47.61905 6 20 42 30 47.61905 1.319 0 0 0006879 iron ion homeostasis P 3 10 16 30 62.5 4 12 18 33.33333 66.66666 1.318 0 0 0046916 transition metal ion homeostasis P 0 0 0 0 0 4 12 20 33.33333 60 1.318 0 0 0006383 transcription from Pol III promoter P 4 10 14 40 71.42857 5 16 22 31.25 72.72727 1.308 0 0 0006944 membrane fusion P 5 12 15 41.66667 80 5 16 21 31.25 76.19048 1.308 0 0 0030145 manganese ion binding F 9 33 41 27.27273 80.48781 9 33 41 27.27273 80.48781 1.292 0 0 0006333 chromatin assembly/disassembly P 3 14 37 21.42857 37.83784 9 33 120 27.27273 27.5 1.292 0 0 0008420 CTD phosphatase activity F 8 29 39 27.58621 74.35897 8 29 39 27.58621 74.35897 1.254 0 0 0019222 regulation of metabolism P 0 0 0 0 0 8 29 49 27.58621 59.18367 1.254 0 0 0030357 protein phosphatase type 2B activity F 8 28 38 28.57143 73.68421 8 29 39 27.58621 74.35897 1.254 0 0 0015071 protein phosphatase type 2C activity F 8 29 39 27.58621 74.35897 8 29 39 27.58621 74.35897 1.254 0 0 0004724 magnesium-dependent protein serine/threonine phosphatase activity F 8 29 39 27.58621 74.35897 8 29 39 27.58621 74.35897 1.254 0 0 0003927 heterotrimeric G-protein GTPase activity F 8 29 50 27.58621 58 8 29 50 27.58621 58 1.254 0 0 0017018 myosin phosphatase activity F 8 29 39 27.58621 74.35897 8 29 39 27.58621 74.35897 1.254 0 0 0003774 motor activity F 5 39 118 12.82051 33.05085 14 56 175 25 32 1.246 0 0 0005504 fatty acid binding F 2 5 7 40 71.42857 2 5 7 40 71.42857 1.234 0 0 0042054 histone methyltransferase activity F 0 0 0 0 0 2 5 9 40 55.55556 1.234 0 0 0005952 cAMP-dependent protein kinase complex C 2 5 11 40 45.45454 2 5 11 40 45.45454 1.234 0 0 0006739 NADPH metabolism P 0 0 1 0 0 2 5 12 40 41.66667 1.234 0 0 0006740 NADPH regeneration P 0 0 0 0 0 2 5 11 40 45.45454 1.234 0 0 0006098 pentose-phosphate shunt P 1 4 9 25 44.44444 2 5 11 40 45.45454 1.234 0 0 0018346 protein amino acid prenylation P 2 5 12 40 41.66667 2 5 12 40 41.66667 1.234 0 0 0007089 start control point of mitotic cell cycle P 2 5 6 40 83.33334 2 5 6 40 83.33334 1.234 0 0 0007062 sister chromatid cohesion P 1 3 3 33.33333 100 2 5 5 40 100 1.234 0 0 0016278 lysine N-methyltransferase activity F 0 0 0 0 0 2 5 9 40 55.55556 1.234 0 0 0008172 S-methyltransferase activity F 0 0 0 0 0 2 5 7 40 71.42857 1.234 0 0 0007163 establishment and/or maintenance of cell polarity P 2 5 7 40 71.42857 2 5 7 40 71.42857 1.234 0 0 0005647 importin\, alpha-subunit C 2 5 6 40 83.33334 2 5 6 40 83.33334 1.234 0 0 0018024 histone-lysine N-methyltransferase activity F 2 5 9 40 55.55556 2 5 9 40 55.55556 1.234 0 0 0004047 aminomethyltransferase activity F 2 5 7 40 71.42857 2 5 7 40 71.42857 1.234 0 0 0005885 Arp2/3 protein complex C 2 5 7 40 71.42857 2 5 7 40 71.42857 1.234 0 0 0007025 beta-tubulin folding P 2 5 5 40 100 2 5 5 40 100 1.234 0 0 0018342 protein prenylation P 0 0 0 0 0 2 5 12 40 41.66667 1.234 0 0 0006555 methionine metabolism P 1 1 4 100 25 2 5 8 40 62.5 1.234 0 0 0016832 aldehyde-lyase activity F 0 0 0 0 0 2 5 6 40 83.33334 1.234 0 0 0008290 F-actin capping protein complex C 2 5 7 40 71.42857 2 5 7 40 71.42857 1.234 0 0 0046146 tetrahydrobiopterin metabolism P 0 0 0 0 0 2 5 5 40 100 1.234 0 0 0004849 uridine kinase activity F 2 5 11 40 45.45454 2 5 11 40 45.45454 1.234 0 0 0005876 spindle microtubule C 2 3 4 66.66666 75 2 5 6 40 83.33334 1.234 0 0 0005666 DNA-directed RNA polymerase III complex C 2 5 7 40 71.42857 2 5 7 40 71.42857 1.234 0 0 0016279 protein-lysine N-methyltransferase activity F 0 0 0 0 0 2 5 9 40 55.55556 1.234 0 0 0008091 spectrin C 2 5 9 40 55.55556 2 5 9 40 55.55556 1.234 0 0 0006729 tetrahydrobiopterin biosynthesis P 2 5 5 40 100 2 5 5 40 100 1.234 0 0 0016829 lyase activity F 17 73 113 23.28767 64.60177 21 89 154 23.5955 57.79221 1.232 0 0 0003676 nucleic acid binding F 31 154 665 20.12987 23.15789 279 1418 3458 19.6756 41.00636 1.219 0 0 0005254 chloride channel activity F 0 2 2 0 100 7 25 36 28 69.44444 1.217 0 0 0005768 endosome C 5 22 31 22.72727 70.96774 7 25 38 28 65.78947 1.217 0 0 0016053 organic acid biosynthesis P 0 0 0 0 0 9 34 52 26.47059 65.38461 1.191 0 0 0046394 carboxylic acid biosynthesis P 0 0 0 0 0 9 34 52 26.47059 65.38461 1.191 0 0 0008757 S-adenosylmethionine-dependent methyltransferase activity F 3 18 45 16.66667 40 11 43 85 25.5814 50.58823 1.189 0 0 0009615 response to virus P 6 19 29 31.57895 65.51724 6 21 32 28.57143 65.625 1.183 0 0 0005200 structural constituent of cytoskeleton F 14 57 113 24.5614 50.44248 14 57 113 24.5614 50.44248 1.172 0 0 0007018 microtubule-based movement P 4 14 63 28.57143 22.22222 5 17 68 29.41176 25 1.153 0 0 0030117 membrane coat C 0 0 0 0 0 5 17 35 29.41176 48.57143 1.153 0 0 0030120 vesicle coat C 0 0 0 0 0 5 17 35 29.41176 48.57143 1.153 0 0 0000123 histone acetyltransferase complex C 0 0 0 0 0 5 17 18 29.41176 94.44444 1.153 0 0 0030705 cytoskeleton-dependent intracellular transport P 0 0 0 0 0 5 17 68 29.41176 25 1.153 0 0 0009306 protein secretion P 5 17 30 29.41176 56.66667 5 17 30 29.41176 56.66667 1.153 0 0 0004723 calcium-dependent protein serine/threonine phosphatase activity F 8 30 41 26.66667 73.17073 8 30 41 26.66667 73.17073 1.146 0 0 0006310 DNA recombination P 4 14 41 28.57143 34.14634 8 30 69 26.66667 43.47826 1.146 0 0 0004660 protein farnesyltransferase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0004406 H3/H4 histone acetyltransferase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0000796 condensin complex C 1 1 1 100 100 1 2 2 50 100 1.144 0 0 0005345 purine transporter activity F 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0000138 Golgi trans cisterna C 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0008508 bile acid\:sodium symporter activity F 1 2 5 50 40 1 2 5 50 40 1.144 0 0 0016326 kinesin motor activity F 1 1 4 100 25 1 2 5 50 40 1.144 0 0 0008523 sodium dependent multivitamin transporter activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0045569 TRAIL binding F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0015205 nucleobase transporter activity F 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0006436 tryptophanyl-tRNA aminoacylation P 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0030151 molybdenum ion binding F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0016281 eukaryotic translation initiation factor 4F complex C 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0008312 7S RNA binding F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0005546 phosphatidylinositol-4\,5-bisphosphate binding F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0003863 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0007033 vacuole organization and biogenesis P 0 1 1 0 100 1 2 2 50 100 1.144 0 0 0042043 neurexin binding F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0004379 glycylpeptide N-tetradecanoyltransferase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0006434 seryl-tRNA aminoacylation P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0006621 protein-ER retention P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0004830 tryptophan-tRNA ligase activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0006499 N-terminal protein myristoylation P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0004766 spermidine synthase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0006504 C-terminal protein geranylgeranylation P 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0045192 low-density lipoprotein catabolism P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0009301 snRNA transcription P 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0006503 C-terminal protein farnesylation P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0004828 serine-tRNA ligase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0005486 t-SNARE activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0009303 rRNA transcription P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0015074 DNA integration P 1 2 8 50 25 1 2 8 50 25 1.144 0 0 0008598 protein phosphatase type 1\, intrinsic catalyst activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0005895 interleukin-5 receptor complex C 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0004083 bisphosphoglycerate phosphatase activity F 1 2 4 50 50 1 2 4 50 50 1.144 0 0 0004082 bisphosphoglycerate mutase activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0004822 isoleucine-tRNA ligase activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0006428 isoleucyl-tRNA aminoacylation P 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0004525 ribonuclease III activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0008492 cAMP generating peptide activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0004064 arylesterase activity F 1 2 5 50 40 1 2 5 50 40 1.144 0 0 0006282 regulation of DNA repair P 1 2 5 50 40 1 2 6 50 33.33333 1.144 0 0 0004063 aryldialkylphosphatase activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0005045 endoplasmic reticulum receptor activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0006422 aspartyl-tRNA aminoacylation P 1 2 4 50 50 1 2 4 50 50 1.144 0 0 0004815 aspartate-tRNA ligase activity F 1 2 4 50 50 1 2 4 50 50 1.144 0 0 0004791 thioredoxin-disulfide reductase activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0009154 purine ribonucleotide catabolism P 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0008054 cyclin catabolism P 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0008615 pyridoxine biosynthesis P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0005049 nuclear export signal receptor activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0042162 telomeric DNA binding F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0008974 phosphoribulokinase activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0005801 Golgi cis-face C 1 2 4 50 50 1 2 4 50 50 1.144 0 0 0004013 adenosylhomocysteinase activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0005685 snRNP U1 C 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0005808 Golgi-plasma membrane transport vesicle C 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0004526 ribonuclease P activity F 1 2 8 50 25 1 2 8 50 25 1.144 0 0 0030127 COPII vesicle coat C 1 2 4 50 50 1 2 4 50 50 1.144 0 0 0008889 glycerophosphodiester phosphodiesterase activity F 1 2 8 50 25 1 2 8 50 25 1.144 0 0 0008746 NAD(P) transhydrogenase activity F 0 1 1 0 100 1 2 3 50 66.66666 1.144 0 0 0000120 RNA polymerase I transcription factor complex C 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0003896 DNA primase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0006622 protein-lysosome targeting P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0005436 sodium\:phosphate symporter activity F 1 2 5 50 40 1 2 5 50 40 1.144 0 0 0007009 plasma membrane organization and biogenesis P 1 1 1 100 100 1 2 5 50 40 1.144 0 0 0005750 respiratory chain complex III (sensu Eukarya) C 0 1 2 0 50 1 2 7 50 28.57143 1.144 0 0 0006195 purine nucleotide catabolism P 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0007023 post-chaperonin tubulin folding pathway P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0008969 phosphohistidine phosphatase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0009399 nitrogen fixation P 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0015079 potassium ion transporter activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0006788 heme oxidation P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0004563 beta-N-acetylhexosaminidase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0007379 segment specification P 1 1 1 100 100 1 2 4 50 50 1.144 0 0 0005811 lipid particle C 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0004477 methenyltetrahydrofolate cyclohydrolase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0008159 positive transcription elongation factor activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0007492 endoderm development P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0046923 ER retention sequence binding F 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0004486 methylenetetrahydrofolate dehydrogenase activity F 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0008156 negative regulation of DNA replication P 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0008301 DNA bending activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0016742 hydroxymethyl-\, formyl- and related transferase activity F 0 1 4 0 25 1 2 6 50 33.33333 1.144 0 0 0008043 ferritin complex C 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0004217 cathepsin L activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0006880 intracellular iron ion storage P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0007175 negative regulation of EGF receptor activity P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0045275 respiratory chain complex III C 0 0 0 0 0 1 2 11 50 18.18182 1.144 0 0 0004967 glucagon receptor activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0030236 anti-inflammatory response P 1 2 4 50 50 1 2 4 50 50 1.144 0 0 0015207 adenine transporter activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0006166 purine salvage P 1 2 3 50 66.66666 1 2 4 50 50 1.144 0 0 0009317 acetyl-CoA carboxylase complex C 0 0 0 0 0 1 2 5 50 40 1.144 0 0 0006110 regulation of glycolysis P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0006551 leucine metabolism P 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0006087 pyruvate dehydrogenase bypass P 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0004457 lactate dehydrogenase activity F 0 0 0 0 0 1 2 6 50 33.33333 1.144 0 0 0004392 heme oxygenase (decyclizing) activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0005132 interferon-alpha/beta receptor binding F 1 2 9 50 22.22222 1 2 9 50 22.22222 1.144 0 0 0042816 vitamin B6 metabolism P 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0005648 importin\, beta-subunit C 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0005137 interleukin-5 receptor binding F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0009880 embryonic pattern specification P 0 0 0 0 0 1 2 4 50 50 1.144 0 0 0009966 regulation of signal transduction P 1 1 1 100 100 1 2 2 50 100 1.144 0 0 0006441 binding to mRNA cap P 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0006102 isocitrate metabolism P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0004074 biliverdin reductase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0003880 C-terminal protein carboxyl methyltransferase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0016454 C-palmitoyltransferase activity F 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0006101 citrate metabolism P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0008281 sulfonylurea receptor activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0005879 axonemal microtubule C 0 0 0 0 0 1 2 9 50 22.22222 1.144 0 0 0004372 glycine hydroxymethyltransferase activity F 0 0 4 0 0 1 2 10 50 20 1.144 0 0 0045502 dynein binding F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0004167 dopachrome isomerase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0000244 assembly of spliceosomal tri-snRNP P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0007612 learning P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0016433 rRNA (adenine) methyltransferase activity F 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0003775 axonemal motor activity F 1 2 7 50 28.57143 1 2 7 50 28.57143 1.144 0 0 0016072 rRNA metabolism P 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0006291 pyrimidine-dimer repair\, DNA damage excision P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0007091 mitotic metaphase/anaphase transition P 0 0 2 0 0 1 2 4 50 50 1.144 0 0 0007632 visual behavior P 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0008649 rRNA methyltransferase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0000154 rRNA modification P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0000179 rRNA (adenine-N6\,N6-)-dimethyltransferase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0019737 quinol\:fumarate oxidoreductase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0008177 succinate dehydrogenase (ubiquinone) activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0005858 axonemal dynein complex C 1 2 9 50 22.22222 1 2 9 50 22.22222 1.144 0 0 0046128 purine ribonucleoside metabolism P 0 0 0 0 0 1 2 4 50 50 1.144 0 0 0008614 pyridoxine metabolism P 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0042819 vitamin B6 biosynthesis P 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0005902 microvillus C 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0008350 kinetochore motor activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0001518 voltage-gated sodium channel complex C 1 2 11 50 18.18182 1 2 11 50 18.18182 1.144 0 0 0008462 endopeptidase Clp activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0005046 KDEL sequence binding F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0005851 eukaryotic translation initiation factor 2B complex C 1 2 5 50 40 1 2 5 50 40 1.144 0 0 0000387 spliceosomal snRNP biogenesis P 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0009460 cytochrome b F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0042278 purine nucleoside metabolism P 0 0 0 0 0 1 2 4 50 50 1.144 0 0 0030331 estrogen receptor binding F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0019856 pyrimidine base biosynthesis P 0 1 1 0 100 1 2 6 50 33.33333 1.144 0 0 0005037 death receptor adaptor protein activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0004108 citrate (Si)-synthase activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0042577 lipid phosphatase activity F 0 0 0 0 0 1 2 5 50 40 1.144 0 0 0003985 acetyl-CoA C-acetyltransferase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0016635 oxidoreductase activity\, acting on the CH-CH group of donors\, quinone or related compound as acceptor F 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0009312 oligosaccharide biosynthesis P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0006475 internal protein amino acid acetylation P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0016670 oxidoreductase activity\, acting on sulfur group of donors\, oxygen as acceptor F 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0003715 transcription termination factor activity F 1 1 2 100 50 1 2 3 50 66.66666 1.144 0 0 0016839 other carbon-oxygen lyase activity F 0 0 0 0 0 1 2 4 50 50 1.144 0 0 0018377 protein myristoylation P 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0030138 COPII-coated vesicle C 0 0 0 0 0 1 2 5 50 40 1.144 0 0 0000152 nuclear ubiquitin ligase complex C 0 0 0 0 0 1 2 6 50 33.33333 1.144 0 0 0019107 myristoyltransferase activity F 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0007183 SMAD protein heteromerization P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0010035 response to inorganic substance P 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0016802 trialkylsulfonium hydrolase activity F 0 0 0 0 0 1 2 3 50 66.66666 1.144 0 0 0004459 L-lactate dehydrogenase activity F 1 2 6 50 33.33333 1 2 6 50 33.33333 1.144 0 0 0004758 serine C-palmitoyltransferase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0006400 tRNA modification P 1 2 3 50 66.66666 1 2 5 50 40 1.144 0 0 0004069 aspartate transaminase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0018319 protein amino acid myristoylation P 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0009343 biotin carboxylase complex C 1 2 5 50 40 1 2 5 50 40 1.144 0 0 0005343 organic acid\:sodium symporter activity F 0 0 0 0 0 1 2 5 50 40 1.144 0 0 0005860 non-muscle myosin C 1 2 5 50 40 1 2 5 50 40 1.144 0 0 0000703 pyrimidine-specific oxidized base lesion DNA N-glycosylase activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0000702 oxidized base lesion DNA N-glycosylase activity F 0 0 0 0 0 1 2 4 50 50 1.144 0 0 0004356 glutamate-ammonia ligase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0015307 drug\:hydrogen antiporter activity F 0 0 0 0 0 1 2 10 50 20 1.144 0 0 0003906 DNA-(apurinic or apyrimidinic site) lyase activity F 0 0 0 0 0 1 2 4 50 50 1.144 0 0 0016363 nuclear matrix C 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0000014 single-stranded DNA specific endodeoxyribonuclease activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0006552 leucine catabolism P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0000019 regulation of mitotic recombination P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0004485 methylcrotonoyl-CoA carboxylase activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0004473 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP) activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0006090 pyruvate metabolism P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0015232 heme transporter activity F 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0015105 arsenite transporter activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.144 0 0 0004239 methionyl aminopeptidase activity F 1 2 4 50 50 1 2 4 50 50 1.144 0 0 0005680 anaphase-promoting complex C 1 2 6 50 33.33333 1 2 6 50 33.33333 1.144 0 0 0008174 mRNA methyltransferase activity F 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0043005 neuronal cell projection C 0 0 0 0 0 1 2 3 50 66.66666 1.144 0 0 0016842 amidine-lyase activity F 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0008089 anterograde axon cargo transport P 1 2 5 50 40 1 2 5 50 40 1.144 0 0 0042159 lipoprotein catabolism P 0 0 0 0 0 1 2 2 50 100 1.144 0 0 0046685 response to arsenate P 1 2 2 50 100 1 2 2 50 100 1.144 0 0 0009309 amine biosynthesis P 0 1 1 0 100 10 39 68 25.64103 57.35294 1.142 0 0 0015631 tubulin binding F 1 2 6 50 33.33333 3 9 23 33.33333 39.13044 1.141 0 0 0016866 intramolecular transferase activity F 0 0 0 0 0 3 9 18 33.33333 50 1.141 0 0 0006607 NLS-bearing substrate-nucleus import P 3 9 11 33.33333 81.81818 3 9 11 33.33333 81.81818 1.141 0 0 0004028 aldehyde dehydrogenase activity F 0 0 0 0 0 3 9 12 33.33333 75 1.141 0 0 0004693 cyclin-dependent protein kinase activity F 3 8 12 37.5 66.66666 3 9 14 33.33333 64.28571 1.141 0 0 0006081 aldehyde metabolism P 2 8 8 25 100 3 9 11 33.33333 81.81818 1.141 0 0 0009066 aspartate family amino acid metabolism P 0 0 0 0 0 3 9 13 33.33333 69.23077 1.141 0 0 0016646 oxidoreductase activity\, acting on the CH-NH group of donors\, NAD or NADP as acceptor F 0 0 0 0 0 3 9 19 33.33333 47.36842 1.141 0 0 0006541 glutamine metabolism P 1 4 9 25 44.44444 3 9 21 33.33333 42.85714 1.141 0 0 0003930 RAS small monomeric GTPase activity F 4 13 40 30.76923 32.5 4 13 40 30.76923 32.5 1.134 0 0 0005669 transcription factor TFIID complex C 4 13 14 30.76923 92.85714 4 13 14 30.76923 92.85714 1.134 0 0 0006399 tRNA metabolism P 0 0 0 0 0 4 13 36 30.76923 36.11111 1.134 0 0 0000786 nucleosome C 4 13 69 30.76923 18.84058 4 13 69 30.76923 18.84058 1.134 0 0 0003779 actin binding F 18 95 212 18.94737 44.81132 26 115 241 22.6087 47.71784 1.128 0 0 0005794 Golgi apparatus C 30 145 227 20.68966 63.87665 39 179 287 21.78771 62.36934 1.128 0 0 0016779 nucleotidyltransferase activity F 0 7 14 0 50 13 53 132 24.5283 40.15152 1.123 0 0 0005874 microtubule C 1 12 47 8.333333 25.53192 7 26 75 26.92308 34.66667 1.1 0 0 0009889 regulation of biosynthesis P 0 0 0 0 0 7 26 38 26.92308 68.42105 1.1 0 0 0006461 protein complex assembly P 12 61 85 19.67213 71.76471 16 68 92 23.52941 73.91304 1.061 0 0 0019897 extrinsic to plasma membrane C 0 0 0 0 0 6 22 45 27.27273 48.88889 1.054 0 0 0046467 membrane lipid biosynthesis P 0 0 0 0 0 8 31 46 25.80645 67.3913 1.041 0 0 0016282 eukaryotic 43S preinitiation complex C 0 0 0 0 0 8 31 41 25.80645 75.60976 1.041 0 0 0030003 cation homeostasis P 0 0 0 0 0 8 31 58 25.80645 53.44828 1.041 0 0 0000163 protein phosphatase type 1 activity F 0 1 1 0 100 8 31 41 25.80645 75.60976 1.041 0 0 0006643 membrane lipid metabolism P 0 1 1 0 100 15 64 96 23.4375 66.66666 1.01 0 0 0003800 antiviral response protein activity F 5 18 30 27.77778 60 5 18 30 27.77778 60 1.008 0 0 0003725 double-stranded RNA binding F 5 18 37 27.77778 48.64865 5 18 37 27.77778 48.64865 1.008 0 0 0008483 transaminase activity F 3 8 27 37.5 29.62963 5 18 41 27.77778 43.90244 1.008 0 0 0003755 peptidyl-prolyl cis-trans isomerase activity F 0 3 3 0 100 5 18 32 27.77778 56.25 1.008 0 0 0016769 transferase activity\, transferring nitrogenous groups F 0 0 0 0 0 5 18 41 27.77778 43.90244 1.008 0 0 0007126 meiosis P 4 18 25 22.22222 72 7 27 38 25.92593 71.05264 0.987 0 0 0000096 sulfur amino acid metabolism P 1 1 1 100 100 4 14 20 28.57143 70 0.965 0 0 0003678 DNA helicase activity F 0 6 8 0 75 4 14 32 28.57143 43.75 0.965 0 0 0016620 oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor F 0 0 0 0 0 4 14 19 28.57143 73.68421 0.965 0 0 0005792 microsome C 15 65 110 23.07692 59.09091 15 65 110 23.07692 59.09091 0.943 0 0 0042598 vesicular fraction C 0 0 1 0 0 15 65 111 23.07692 58.55856 0.943 0 0 0005717 chromatin C 3 10 13 30 76.92308 3 10 13 30 76.92308 0.932 0 0 0008166 viral replication P 3 10 13 30 76.92308 3 10 13 30 76.92308 0.932 0 0 0007292 female gamete generation P 3 9 16 33.33333 56.25 3 10 18 30 55.55556 0.932 0 0 0000080 G1 phase of mitotic cell cycle P 1 4 7 25 57.14286 3 10 15 30 66.66666 0.932 0 0 0016877 ligase activity\, forming carbon-sulfur bonds F 0 0 0 0 0 3 10 15 30 66.66666 0.932 0 0 0008154 actin polymerization and/or depolymerization P 1 5 5 20 100 3 10 12 30 83.33334 0.932 0 0 0000228 nuclear chromosome C 2 6 11 33.33333 54.54546 3 10 19 30 52.63158 0.932 0 0 0006891 intra-Golgi transport P 3 10 16 30 62.5 3 10 16 30 62.5 0.932 0 0 0006041 glucosamine metabolism P 1 1 1 100 100 2 6 9 33.33333 66.66666 0.932 0 0 0046489 phosphoinositide biosynthesis P 0 0 0 0 0 2 6 9 33.33333 66.66666 0.932 0 0 0046527 glucosyltransferase activity F 0 0 0 0 0 2 6 8 33.33333 75 0.932 0 0 0005869 dynactin complex C 2 6 6 33.33333 100 2 6 6 33.33333 100 0.932 0 0 0008603 cAMP-dependent protein kinase\, intrinsic regulator activity F 2 6 15 33.33333 40 2 6 15 33.33333 40 0.932 0 0 0019717 synaptosome C 2 6 10 33.33333 60 2 6 10 33.33333 60 0.932 0 0 0006378 mRNA polyadenylation P 2 6 7 33.33333 85.71429 2 6 7 33.33333 85.71429 0.932 0 0 0005100 Rho GTPase activator activity F 2 6 13 33.33333 46.15385 2 6 13 33.33333 46.15385 0.932 0 0 0006415 translational termination P 1 2 4 50 50 2 6 9 33.33333 66.66666 0.932 0 0 0008443 phosphofructokinase activity F 0 0 0 0 0 2 6 8 33.33333 75 0.932 0 0 0005678 chromatin assembly complex C 2 6 6 33.33333 100 2 6 6 33.33333 100 0.932 0 0 0003782 F-actin capping activity F 2 4 6 50 66.66666 2 6 8 33.33333 75 0.932 0 0 0015223 vitamin/cofactor transporter activity F 0 0 0 0 0 2 6 10 33.33333 60 0.932 0 0 0006071 glycerol metabolism P 1 3 9 33.33333 33.33333 2 6 17 33.33333 35.29412 0.932 0 0 0005884 actin filament C 2 6 17 33.33333 35.29412 2 6 17 33.33333 35.29412 0.932 0 0 0008299 isoprenoid biosynthesis P 2 6 12 33.33333 50 2 6 12 33.33333 50 0.932 0 0 0000118 histone deacetylase complex C 2 6 13 33.33333 46.15385 2 6 13 33.33333 46.15385 0.932 0 0 0005484 SNAP receptor activity F 1 2 2 50 100 2 6 6 33.33333 100 0.932 0 0 0008543 FGF receptor signaling pathway P 2 6 8 33.33333 75 2 6 8 33.33333 75 0.932 0 0 0003767 co-chaperone activity F 1 2 4 50 50 2 6 8 33.33333 75 0.932 0 0 0005663 DNA replication factor C complex C 2 6 13 33.33333 46.15385 2 6 13 33.33333 46.15385 0.932 0 0 0030384 phosphoinositide metabolism P 0 0 1 0 0 2 6 10 33.33333 60 0.932 0 0 0019898 extrinsic to membrane C 0 1 1 0 100 6 23 46 26.08696 50 0.931 0 0 0019725 cell homeostasis P 0 0 0 0 0 9 37 66 24.32432 56.06061 0.906 0 0 0015934 large ribosomal subunit C 0 4 8 0 50 9 37 54 24.32432 68.51852 0.906 0 0 0042592 homeostasis P 0 0 0 0 0 9 37 67 24.32432 55.22388 0.906 0 0 0016830 carbon-carbon lyase activity F 0 0 0 0 0 5 19 34 26.31579 55.88235 0.872 0 0 0016859 cis-trans isomerase activity F 0 0 0 0 0 5 19 33 26.31579 57.57576 0.872 0 0 0016903 oxidoreductase activity\, acting on the aldehyde or oxo group of donors F 0 0 0 0 0 5 19 31 26.31579 61.29032 0.872 0 0 0000287 magnesium ion binding F 19 86 146 22.09302 58.90411 19 86 146 22.09302 58.90411 0.85 0 0 0006979 response to oxidative stress P 8 31 61 25.80645 50.81967 8 33 64 24.24242 51.5625 0.843 0 0 0008092 cytoskeletal protein binding F 0 5 10 0 50 29 136 288 21.32353 47.22222 0.839 0 0 0006730 one-carbon compound metabolism P 6 21 31 28.57143 67.74194 6 24 35 25 68.57143 0.814 0 0 0005544 calcium-dependent phospholipid binding F 4 15 17 26.66667 88.23529 4 15 17 26.66667 88.23529 0.809 0 0 0006767 water-soluble vitamin metabolism P 0 0 0 0 0 4 15 27 26.66667 55.55556 0.809 0 0 0016582 non-covalent chromatin modification P 0 0 0 0 0 4 15 34 26.66667 44.11765 0.809 0 0 0030118 clathrin coat C 0 0 0 0 0 4 15 31 26.66667 48.3871 0.809 0 0 0030125 clathrin vesicle coat C 4 14 25 28.57143 56 4 15 31 26.66667 48.3871 0.809 0 0 0007265 RAS protein signal transduction P 4 15 23 26.66667 65.21739 4 15 23 26.66667 65.21739 0.809 0 0 0006338 chromatin modeling P 3 13 17 23.07692 76.47059 4 15 34 26.66667 44.11765 0.809 0 0 0019207 kinase regulator activity F 0 0 0 0 0 7 29 52 24.13793 55.76923 0.775 0 0 0006873 cell ion homeostasis P 0 3 3 0 100 8 34 62 23.52941 54.83871 0.748 0 0 0019904 protein domain specific binding F 1 6 10 16.66667 60 3 11 17 27.27273 64.70588 0.745 0 0 0004869 cysteine protease inhibitor activity F 3 11 26 27.27273 42.30769 3 11 29 27.27273 37.93103 0.745 0 0 0016811 hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds\, in linear amides F 0 0 0 0 0 6 25 46 24 54.34783 0.702 0 0 0016251 general RNA polymerase II transcription factor activity F 6 21 22 28.57143 95.45454 6 25 33 24 75.75758 0.702 0 0 0005996 monosaccharide metabolism P 0 0 0 0 0 14 64 114 21.875 56.14035 0.687 0 0 0003895 gamma DNA-directed DNA polymerase activity F 2 7 13 28.57143 53.84615 2 7 13 28.57143 53.84615 0.682 0 0 0016863 intramolecular isomerase activity\, transposing C=C bonds F 0 0 0 0 0 2 7 12 28.57143 58.33333 0.682 0 0 0006720 isoprenoid metabolism P 0 0 0 0 0 2 7 13 28.57143 53.84615 0.682 0 0 0003894 zeta DNA polymerase activity F 2 7 13 28.57143 53.84615 2 7 13 28.57143 53.84615 0.682 0 0 0003891 delta DNA polymerase activity F 2 7 15 28.57143 46.66667 2 7 15 28.57143 46.66667 0.682 0 0 0016449 lambda DNA polymerase activity F 2 7 13 28.57143 53.84615 2 7 13 28.57143 53.84615 0.682 0 0 0016452 theta DNA polymerase activity F 2 7 13 28.57143 53.84615 2 7 13 28.57143 53.84615 0.682 0 0 0016451 nu DNA polymerase activity F 2 7 13 28.57143 53.84615 2 7 13 28.57143 53.84615 0.682 0 0 0017125 deoxycytidyl transferase activity F 0 0 0 0 0 2 7 13 28.57143 53.84615 0.682 0 0 0016450 kappa DNA polymerase activity F 2 7 13 28.57143 53.84615 2 7 13 28.57143 53.84615 0.682 0 0 0008017 microtubule binding F 2 7 17 28.57143 41.17647 2 7 17 28.57143 41.17647 0.682 0 0 0006801 superoxide metabolism P 2 7 11 28.57143 63.63636 2 7 11 28.57143 63.63636 0.682 0 0 0016448 mu DNA polymerase activity F 2 7 13 28.57143 53.84615 2 7 13 28.57143 53.84615 0.682 0 0 0003889 alpha DNA polymerase activity F 2 7 13 28.57143 53.84615 2 7 13 28.57143 53.84615 0.682 0 0 0016000 iota DNA polymerase activity F 2 7 13 28.57143 53.84615 2 7 13 28.57143 53.84615 0.682 0 0 0019984 sigma DNA polymerase activity F 2 7 13 28.57143 53.84615 2 7 13 28.57143 53.84615 0.682 0 0 0003950 NAD ADP-ribosyltransferase activity F 2 7 11 28.57143 63.63636 2 7 11 28.57143 63.63636 0.682 0 0 0016846 carbon-sulfur lyase activity F 0 0 0 0 0 2 7 14 28.57143 50 0.682 0 0 0016628 oxidoreductase activity\, acting on the CH-CH group of donors\, NAD or NADP as acceptor F 0 0 0 0 0 2 7 11 28.57143 63.63636 0.682 0 0 0009156 ribonucleoside monophosphate biosynthesis P 1 2 4 50 50 2 7 19 28.57143 36.84211 0.682 0 0 0003727 single-stranded RNA binding F 1 3 4 33.33333 75 2 7 10 28.57143 70 0.682 0 0 0006769 nicotinamide metabolism P 0 0 0 0 0 2 7 16 28.57143 43.75 0.682 0 0 0019986 deoxycytidyl transferase activity\, template dependent F 2 7 13 28.57143 53.84615 2 7 13 28.57143 53.84615 0.682 0 0 0019362 pyridine nucleotide metabolism P 0 0 0 0 0 2 7 17 28.57143 41.17647 0.682 0 0 0008037 cell recognition P 2 3 7 66.66666 42.85714 2 7 12 28.57143 58.33333 0.682 0 0 0015718 monocarboxylic acid transport P 0 3 5 0 60 2 7 11 28.57143 63.63636 0.682 0 0 0019751 polyol metabolism P 0 0 0 0 0 2 7 18 28.57143 38.88889 0.682 0 0 0009161 ribonucleoside monophosphate metabolism P 0 0 0 0 0 2 7 19 28.57143 36.84211 0.682 0 0 0005912 adherens junction C 1 2 2 50 100 2 7 10 28.57143 70 0.682 0 0 0016718 oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, miscellaneous F 0 0 0 0 0 2 7 13 28.57143 53.84615 0.682 0 0 0030552 3’\,5’-cAMP binding F 2 7 12 28.57143 58.33333 2 7 12 28.57143 58.33333 0.682 0 0 0015672 monovalent inorganic cation transport P 0 0 0 0 0 31 150 332 20.66667 45.18072 0.673 0 0 0004536 deoxyribonuclease activity F 0 3 4 0 75 4 16 21 25 76.19048 0.664 0 0 0016081 synaptic vesicle docking P 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0006884 regulation of cell volume P 1 2 2 50 100 1 3 3 33.33333 100 0.659 0 0 0005659 delta DNA polymerase complex C 0 0 1 0 0 1 3 5 33.33333 60 0.659 0 0 0004332 fructose-bisphosphate aldolase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0006787 porphyrin catabolism P 0 0 0 0 0 1 3 3 33.33333 100 0.659 0 0 0008898 homocysteine S-methyltransferase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0003926 ARF small monomeric GTPase activity F 1 3 4 33.33333 75 1 3 4 33.33333 75 0.659 0 0 0003789 actin filament severing activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0030055 cell-matrix junction C 0 0 0 0 0 1 3 4 33.33333 75 0.659 0 0 0016421 CoA carboxylase activity F 0 0 0 0 0 1 3 6 33.33333 50 0.659 0 0 0004075 biotin carboxylase activity F 1 3 6 33.33333 50 1 3 6 33.33333 50 0.659 0 0 0006206 pyrimidine base metabolism P 0 1 1 0 100 1 3 7 33.33333 42.85714 0.659 0 0 0003917 DNA topoisomerase type I activity F 1 3 4 33.33333 75 1 3 4 33.33333 75 0.659 0 0 0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0005514 calcium ion storage activity F 1 3 9 33.33333 33.33333 1 3 9 33.33333 33.33333 0.659 0 0 0005640 nuclear outer membrane C 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0004165 dodecenoyl-CoA delta-isomerase activity F 1 3 4 33.33333 75 1 3 4 33.33333 75 0.659 0 0 0006930 substrate-bound cell migration\, cell extension P 1 3 4 33.33333 75 1 3 4 33.33333 75 0.659 0 0 0019798 procollagen-proline dioxygenase activity F 0 0 0 0 0 1 3 3 33.33333 100 0.659 0 0 0042808 neuronal Cdc2-like kinase binding F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0007386 compartment specification P 1 1 1 100 100 1 3 3 33.33333 100 0.659 0 0 0004046 aminoacylase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0003901 DNA-directed RNA polymerase II activity F 1 3 6 33.33333 50 1 3 6 33.33333 50 0.659 0 0 0005924 cell-substrate adherens junction C 0 0 0 0 0 1 3 4 33.33333 75 0.659 0 0 0000184 mRNA catabolism\, nonsense-mediated P 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0009894 regulation of catabolism P 0 0 0 0 0 1 3 11 33.33333 27.27273 0.659 0 0 0008088 axon cargo transport P 0 1 1 0 100 1 3 7 33.33333 42.85714 0.659 0 0 0045893 positive regulation of transcription\, DNA-dependent P 0 2 3 0 66.66666 1 3 5 33.33333 60 0.659 0 0 0005790 smooth endoplasmic reticulum C 1 3 8 33.33333 37.5 1 3 8 33.33333 37.5 0.659 0 0 0000076 DNA replication checkpoint P 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0006047 UDP-N-acetylglucosamine metabolism P 0 2 2 0 100 1 3 3 33.33333 100 0.659 0 0 0018065 protein-cofactor linkage P 0 0 0 0 0 1 3 4 33.33333 75 0.659 0 0 0005675 transcription factor TFIIH complex C 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0042995 cell projection C 0 0 0 0 0 1 3 7 33.33333 42.85714 0.659 0 0 0004844 uracil DNA N-glycosylase activity F 1 3 5 33.33333 60 1 3 5 33.33333 60 0.659 0 0 0006072 glycerol-3-phosphate metabolism P 1 3 8 33.33333 37.5 1 3 8 33.33333 37.5 0.659 0 0 0016211 ammonia ligase activity F 0 1 1 0 100 1 3 3 33.33333 100 0.659 0 0 0008354 germ-cell migration P 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0016413 O-acetyltransferase activity F 0 0 0 0 0 1 3 3 33.33333 100 0.659 0 0 0004656 procollagen-proline 4-dioxygenase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0003794 acute-phase response protein activity F 1 3 6 33.33333 50 1 3 6 33.33333 50 0.659 0 0 0005660 delta-DNA polymerase cofactor complex C 1 3 4 33.33333 75 1 3 4 33.33333 75 0.659 0 0 0006534 cysteine metabolism P 1 1 2 100 50 1 3 4 33.33333 75 0.659 0 0 0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity F 1 3 5 33.33333 60 1 3 5 33.33333 60 0.659 0 0 0017124 SH3-domain binding F 1 3 4 33.33333 75 1 3 4 33.33333 75 0.659 0 0 0007159 leukocyte cell adhesion P 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0008573 peroxisome-assembly ATPase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0009119 ribonucleoside metabolism P 0 0 0 0 0 1 3 5 33.33333 60 0.659 0 0 0004661 protein geranylgeranyltransferase activity F 1 1 1 100 100 1 3 5 33.33333 60 0.659 0 0 0016299 regulator of G-protein signaling activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0005007 fibroblast growth factor receptor activity F 1 3 7 33.33333 42.85714 1 3 7 33.33333 42.85714 0.659 0 0 0009650 UV protection P 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0045941 positive regulation of transcription P 0 0 1 0 0 1 3 6 33.33333 50 0.659 0 0 0005925 focal adhesion C 1 3 4 33.33333 75 1 3 4 33.33333 75 0.659 0 0 0004983 neuropeptide Y receptor activity F 1 3 11 33.33333 27.27273 1 3 11 33.33333 27.27273 0.659 0 0 0009261 ribonucleotide catabolism P 0 0 0 0 0 1 3 3 33.33333 100 0.659 0 0 0005246 calcium channel regulator activity F 1 3 5 33.33333 60 1 3 5 33.33333 60 0.659 0 0 0009249 protein-lipoylation P 1 3 4 33.33333 75 1 3 4 33.33333 75 0.659 0 0 0006353 transcription termination P 1 2 3 50 66.66666 1 3 4 33.33333 75 0.659 0 0 0005716 synaptonemal complex C 1 3 4 33.33333 75 1 3 4 33.33333 75 0.659 0 0 0005505 heavy metal binding F 1 3 8 33.33333 37.5 1 3 8 33.33333 37.5 0.659 0 0 0015355 monocarboxylate porter activity F 1 3 6 33.33333 50 1 3 6 33.33333 50 0.659 0 0 0004709 MAP kinase kinase kinase activity F 1 3 6 33.33333 50 1 3 6 33.33333 50 0.659 0 0 0046912 transferase activity\, transferring acyl groups\, acyl groups converted into alkyl on transfer F 0 0 0 0 0 1 3 7 33.33333 42.85714 0.659 0 0 0006531 aspartate metabolism P 0 0 0 0 0 1 3 4 33.33333 75 0.659 0 0 0006533 aspartate catabolism P 1 3 4 33.33333 75 1 3 4 33.33333 75 0.659 0 0 0015125 bile acid transporter activity F 0 0 3 0 0 1 3 9 33.33333 33.33333 0.659 0 0 0006636 fatty acid desaturation P 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0003902 DNA-directed RNA polymerase III activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0000149 SNARE binding F 0 0 1 0 0 1 3 4 33.33333 75 0.659 0 0 0004111 creatine kinase activity F 1 3 4 33.33333 75 1 3 4 33.33333 75 0.659 0 0 0003963 RNA-3’-phosphate cyclase activity F 1 3 4 33.33333 75 1 3 4 33.33333 75 0.659 0 0 0019905 syntaxin binding F 0 0 0 0 0 1 3 3 33.33333 100 0.659 0 0 0005930 axoneme C 0 1 1 0 100 1 3 11 33.33333 27.27273 0.659 0 0 0006750 glutathione biosynthesis P 1 3 8 33.33333 37.5 1 3 8 33.33333 37.5 0.659 0 0 0006510 ATP-dependent proteolysis P 1 3 8 33.33333 37.5 1 3 8 33.33333 37.5 0.659 0 0 0003988 acetyl-CoA C-acyltransferase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0005532 mannose binding lectin F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0015937 coenzyme A biosynthesis P 1 3 4 33.33333 75 1 3 4 33.33333 75 0.659 0 0 0004594 pantothenate kinase activity F 1 3 4 33.33333 75 1 3 4 33.33333 75 0.659 0 0 0016453 C-acetyltransferase activity F 0 0 0 0 0 1 3 3 33.33333 100 0.659 0 0 0000127 transcription factor TFIIIC complex C 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0006561 proline biosynthesis P 1 3 10 33.33333 30 1 3 10 33.33333 30 0.659 0 0 0008475 procollagen-lysine 5-dioxygenase activity F 1 3 5 33.33333 60 1 3 5 33.33333 60 0.659 0 0 0004634 phosphopyruvate hydratase activity F 1 3 6 33.33333 50 1 3 6 33.33333 50 0.659 0 0 0016485 protein processing P 0 0 0 0 0 1 3 10 33.33333 30 0.659 0 0 0006269 DNA replication\, priming P 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0004735 pyrroline-5-carboxylate reductase activity F 1 3 8 33.33333 37.5 1 3 8 33.33333 37.5 0.659 0 0 0008567 dynein ATPase activity F 1 3 20 33.33333 15 1 3 20 33.33333 15 0.659 0 0 0008330 protein tyrosine/threonine phosphatase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.659 0 0 0008271 sulfate porter activity F 1 3 17 33.33333 17.64706 1 3 18 33.33333 16.66667 0.659 0 0 0015116 sulfate transporter activity F 0 0 0 0 0 1 3 18 33.33333 16.66667 0.659 0 0 0000015 phosphopyruvate hydratase complex C 1 3 6 33.33333 50 1 3 6 33.33333 50 0.659 0 0 0005498 sterol carrier activity F 1 3 7 33.33333 42.85714 1 3 7 33.33333 42.85714 0.659 0 0 0008189 apoptosis inhibitor activity F 8 35 50 22.85714 70 8 35 50 22.85714 70 0.657 0 0 0005575 cellular_component C 0 0 0 0 0 1012 5407 12138 18.71648 44.54605 0.652 0 0 0006766 vitamin metabolism P 1 2 2 50 100 5 21 35 23.80952 60 0.621 0 0 0008307 structural constituent of muscle F 5 21 45 23.80952 46.66667 5 21 45 23.80952 46.66667 0.621 0 0 0005842 cytosolic large ribosomal subunit (sensu Eukarya) C 7 31 40 22.58064 77.5 7 31 40 22.58064 77.5 0.578 0 0 0046903 secretion P 0 0 0 0 0 7 31 56 22.58064 55.35714 0.578 0 0 0006352 transcription initiation P 2 8 9 25 88.88889 7 31 44 22.58064 70.45454 0.578 0 0 0006778 porphyrin metabolism P 0 0 0 0 0 3 12 19 25 63.15789 0.575 0 0 0008408 3’-5’ exonuclease activity F 2 9 18 22.22222 50 3 12 30 25 40 0.575 0 0 0019201 nucleotide kinase activity F 0 0 0 0 0 3 12 18 25 66.66666 0.575 0 0 0007131 meiotic recombination P 3 12 18 25 66.66666 3 12 18 25 66.66666 0.575 0 0 0004089 carbonate dehydratase activity F 3 12 19 25 63.15789 3 12 19 25 63.15789 0.575 0 0 0006874 calcium ion homeostasis P 3 12 20 25 60 3 12 20 25 60 0.575 0 0 0007143 female meiosis P 0 0 0 0 0 3 12 18 25 66.66666 0.575 0 0 0006826 iron ion transport P 3 12 20 25 60 3 12 20 25 60 0.575 0 0 0007144 female meiosis I P 0 0 0 0 0 3 12 18 25 66.66666 0.575 0 0 0008033 tRNA processing P 3 10 28 30 35.71429 3 12 33 25 36.36364 0.575 0 0 0046821 extrachromosomal DNA C 8 36 98 22.22222 36.7347 8 36 100 22.22222 36 0.568 0 0 0000158 protein phosphatase type 2A activity F 6 27 38 22.22222 71.05264 9 41 58 21.95122 70.68965 0.561 0 0 0004009 ATP-binding cassette (ABC) transporter activity F 9 38 85 23.68421 44.70588 9 41 91 21.95122 45.05495 0.561 0 0 0005554 molecular_function unknown F 75 382 941 19.63351 40.59511 75 382 941 19.63351 40.59511 0.559 0 0 0004428 inositol/phosphatidylinositol kinase activity F 3 9 23 33.33333 39.13044 4 17 52 23.52941 32.69231 0.529 0 0 0006631 fatty acid metabolism P 7 35 49 20 71.42857 17 82 119 20.73171 68.90756 0.511 0 0 0006790 sulfur metabolism P 1 1 1 100 100 5 22 34 22.72727 64.70588 0.505 0 0 0006367 transcription initiation from Pol II promoter P 5 22 33 22.72727 66.66666 5 22 33 22.72727 66.66666 0.505 0 0 0015932 nucleobase\, nucleoside\, nucleotide and nucleic acid transporter activity F 0 0 0 0 0 2 8 11 25 72.72727 0.469 0 0 0015999 eta DNA polymerase activity F 2 8 14 25 57.14286 2 8 14 25 57.14286 0.469 0 0 0008318 protein prenyltransferase activity F 2 4 11 50 36.36364 2 8 16 25 50 0.469 0 0 0003890 beta DNA polymerase activity F 2 8 16 25 50 2 8 16 25 50 0.469 0 0 0006040 amino sugar metabolism P 0 1 2 0 50 2 8 12 25 66.66666 0.469 0 0 0009084 glutamine family amino acid biosynthesis P 0 0 0 0 0 2 8 23 25 34.78261 0.469 0 0 0015288 porin activity F 0 5 15 0 33.33333 2 8 18 25 44.44444 0.469 0 0 0016801 hydrolase activity\, acting on ether bonds F 0 0 0 0 0 2 8 13 25 61.53846 0.469 0 0 0016505 apoptotic protease activator activity F 1 1 1 100 100 2 8 8 25 100 0.469 0 0 0005865 striated muscle thin filament C 0 0 1 0 0 2 8 10 25 80 0.469 0 0 0016208 AMP binding F 0 1 1 0 100 2 8 13 25 61.53846 0.469 0 0 0019318 hexose metabolism P 0 0 0 0 0 13 63 112 20.63492 56.25 0.427 0 0 0007548 sex differentiation P 3 13 22 23.07692 59.09091 3 13 22 23.07692 59.09091 0.42 0 0 0006650 glycerophospholipid metabolism P 1 2 2 50 100 3 13 18 23.07692 72.22222 0.42 0 0 0000922 spindle pole C 1 3 3 33.33333 100 4 18 28 22.22222 64.28571 0.401 0 0 0004527 exonuclease activity F 2 10 37 20 27.02703 4 18 57 22.22222 31.57895 0.401 0 0 0006800 oxygen and reactive oxygen species metabolism P 0 0 2 0 0 8 38 75 21.05263 50.66667 0.398 0 0 0016407 acetyltransferase activity F 0 1 2 0 50 5 23 40 21.73913 57.5 0.394 0 0 0046483 heterocycle metabolism P 0 0 0 0 0 6 28 50 21.42857 56 0.392 0 0 0019752 carboxylic acid metabolism P 0 0 0 0 0 42 215 331 19.53488 64.95468 0.376 0 0 0005830 cytosolic ribosome (sensu Eukarya) C 0 1 1 0 100 11 54 71 20.37037 76.05634 0.345 0 0 0006082 organic acid metabolism P 0 0 0 0 0 42 216 333 19.44444 64.86487 0.343 0 0 0007176 regulation of EGF receptor activity P 0 2 2 0 100 1 4 4 25 100 0.332 0 0 0007566 embryo implantation P 1 4 5 25 80 1 4 5 25 80 0.332 0 0 0004041 amine oxidase (flavin-containing) activity F 1 4 4 25 100 1 4 4 25 100 0.332 0 0 0016524 latrotoxin receptor activity F 1 4 14 25 28.57143 1 4 14 25 28.57143 0.332 0 0 0004517 nitric-oxide synthase activity F 1 4 7 25 57.14286 1 4 7 25 57.14286 0.332 0 0 0000211 protein degradation tagging activity F 1 4 5 25 80 1 4 5 25 80 0.332 0 0 0003781 actin bundling activity F 1 4 5 25 80 1 4 5 25 80 0.332 0 0 0003910 DNA ligase (ATP) activity F 1 4 6 25 66.66666 1 4 6 25 66.66666 0.332 0 0 0015804 neutral amino acid transport P 1 3 3 33.33333 100 1 4 4 25 100 0.332 0 0 0004622 lysophospholipase activity F 1 4 8 25 50 1 4 8 25 50 0.332 0 0 0015299 solute\:hydrogen antiporter activity F 0 2 13 0 15.38461 1 4 23 25 17.3913 0.332 0 0 0004630 phospholipase D activity F 1 3 3 33.33333 100 1 4 7 25 57.14286 0.332 0 0 0042100 B-cell proliferation P 1 4 4 25 100 1 4 4 25 100 0.332 0 0 0004556 alpha-amylase activity F 1 4 6 25 66.66666 1 4 6 25 66.66666 0.332 0 0 0005337 nucleoside transporter activity F 1 3 6 33.33333 50 1 4 7 25 57.14286 0.332 0 0 0009103 lipopolysaccharide biosynthesis P 1 4 9 25 44.44444 1 4 9 25 44.44444 0.332 0 0 0005903 brush border C 1 4 5 25 80 1 4 5 25 80 0.332 0 0 0017119 Golgi transport complex C 1 4 5 25 80 1 4 5 25 80 0.332 0 0 0009083 branched chain family amino acid catabolism P 0 2 2 0 100 1 4 4 25 100 0.332 0 0 0006749 glutathione metabolism P 0 1 1 0 100 1 4 9 25 44.44444 0.332 0 0 0003772 co-chaperonin activity F 1 4 4 25 100 1 4 4 25 100 0.332 0 0 0019863 IgE binding F 1 4 5 25 80 1 4 5 25 80 0.332 0 0 0009166 nucleotide catabolism P 0 1 2 0 50 1 4 6 25 66.66666 0.332 0 0 0008526 phosphatidylinositol transporter activity F 1 4 6 25 66.66666 1 4 6 25 66.66666 0.332 0 0 0008246 electron transfer flavoprotein F 1 4 4 25 100 1 4 4 25 100 0.332 0 0 0006449 regulation of translational termination P 1 4 4 25 100 1 4 4 25 100 0.332 0 0 0005955 calcineurin complex C 1 4 4 25 100 1 4 4 25 100 0.332 0 0 0004704 NF-kappaB-inducing kinase activity F 1 4 4 25 100 1 4 4 25 100 0.332 0 0 0008143 poly(A) binding F 1 4 5 25 80 1 4 5 25 80 0.332 0 0 0005545 phosphatidylinositol binding F 0 2 3 0 66.66666 1 4 5 25 80 0.332 0 0 0009395 phospholipid catabolism P 1 3 7 33.33333 42.85714 1 4 9 25 44.44444 0.332 0 0 0019883 antigen presentation\, endogenous antigen P 1 3 12 33.33333 25 1 4 15 25 26.66667 0.332 0 0 0004012 phospholipid-translocating ATPase activity F 1 4 13 25 30.76923 1 4 13 25 30.76923 0.332 0 0 0015858 nucleoside transport P 1 3 3 33.33333 100 1 4 4 25 100 0.332 0 0 0004716 receptor signaling protein tyrosine kinase activity F 1 4 6 25 66.66666 1 4 6 25 66.66666 0.332 0 0 0006911 phagocytosis\, engulfment P 1 4 5 25 80 1 4 5 25 80 0.332 0 0 0003747 translation release factor activity F 1 3 5 33.33333 60 1 4 6 25 66.66666 0.332 0 0 0006069 ethanol oxidation P 1 4 5 25 80 1 4 5 25 80 0.332 0 0 0004023 alcohol dehydrogenase activity\, metal ion-independent F 1 4 7 25 57.14286 1 4 7 25 57.14286 0.332 0 0 0004025 alcohol dehydrogenase activity\, iron-dependent F 1 4 7 25 57.14286 1 4 7 25 57.14286 0.332 0 0 0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity F 1 4 14 25 28.57143 1 4 14 25 28.57143 0.332 0 0 0009396 folic acid and derivative biosynthesis P 1 4 7 25 57.14286 1 4 7 25 57.14286 0.332 0 0 0005947 alpha-ketoglutarate dehydrogenase complex (sensu Eukarya) C 1 4 5 25 80 1 4 5 25 80 0.332 0 0 0015247 aminophospholipid transporter activity F 0 0 0 0 0 1 4 13 25 30.76923 0.332 0 0 0016880 acid-ammonia (or amide) ligase activity F 0 0 0 0 0 1 4 5 25 80 0.332 0 0 0019136 deoxynucleoside kinase activity F 0 0 0 0 0 1 4 4 25 100 0.332 0 0 0008653 lipopolysaccharide metabolism P 0 0 0 0 0 1 4 9 25 44.44444 0.332 0 0 0045240 alpha-ketoglutarate dehydrogenase complex C 0 0 0 0 0 1 4 5 25 80 0.332 0 0 0008638 protein tagging activity F 0 0 0 0 0 1 4 5 25 80 0.332 0 0 0016885 ligase activity\, forming carbon-carbon bonds F 0 0 0 0 0 1 4 7 25 57.14286 0.332 0 0 0006067 ethanol metabolism P 0 0 0 0 0 1 4 5 25 80 0.332 0 0 0016160 amylase activity F 0 0 0 0 0 1 4 6 25 66.66666 0.332 0 0 0016861 intramolecular isomerase activity\, interconverting aldoses and ketoses F 0 0 0 0 0 1 4 10 25 40 0.332 0 0 0046139 coenzymes and prosthetic group catabolism P 0 0 0 0 0 1 4 4 25 100 0.332 0 0 0005862 muscle thin filament tropomyosin C 1 4 4 25 100 1 4 4 25 100 0.332 0 0 0004549 tRNA-specific ribonuclease activity F 0 0 0 0 0 1 4 12 25 33.33333 0.332 0 0 0015298 solute\:cation antiporter activity F 0 0 0 0 0 1 4 23 25 17.3913 0.332 0 0 0003909 DNA ligase activity F 0 0 0 0 0 1 4 7 25 57.14286 0.332 0 0 0045767 regulation of anti-apoptosis P 0 0 0 0 0 1 4 6 25 66.66666 0.332 0 0 0006560 proline metabolism P 0 0 0 0 0 1 4 15 25 26.66667 0.332 0 0 0019058 viral infectious cycle P 0 0 0 0 0 1 4 9 25 44.44444 0.332 0 0 0030062 TCA cycle enzyme complex (sensu Eukarya) C 0 0 0 0 0 1 4 5 25 80 0.332 0 0 0000030 mannosyltransferase activity F 0 0 0 0 0 1 4 4 25 100 0.332 0 0 0016079 synaptic vesicle exocytosis P 0 0 0 0 0 1 4 5 25 80 0.332 0 0 0005861 troponin complex C 1 4 5 25 80 1 4 5 25 80 0.332 0 0 0008242 omega peptidase activity F 0 0 0 0 0 1 4 4 25 100 0.332 0 0 0042364 water-soluble vitamin biosynthesis P 0 0 0 0 0 1 4 8 25 50 0.332 0 0 0015300 solute\:solute antiporter activity F 0 0 1 0 0 1 4 24 25 16.66667 0.332 0 0 0008079 translation termination factor activity F 0 0 0 0 0 1 4 6 25 66.66666 0.332 0 0 0008369 obsolete molecular function F 0 0 0 0 0 32 164 239 19.5122 68.61925 0.32 0 0 0008289 lipid binding F 6 28 55 21.42857 50.90909 18 91 139 19.78022 65.46763 0.303 0 0 0005975 carbohydrate metabolism P 17 110 229 15.45455 48.03493 44 228 441 19.29825 51.70068 0.295 0 0 0008047 enzyme activator activity F 6 26 33 23.07692 78.78788 21 107 166 19.62617 64.45783 0.288 0 0 0006733 oxidoreduction coenzyme metabolism P 0 0 0 0 0 2 9 22 22.22222 40.90909 0.283 0 0 0008629 induction of apoptosis by intracellular signals P 2 6 7 33.33333 85.71429 2 9 16 22.22222 56.25 0.283 0 0 0006641 triacylglycerol metabolism P 0 3 4 0 75 2 9 21 22.22222 42.85714 0.283 0 0 0016585 chromatin remodeling complex C 0 1 2 0 50 2 9 23 22.22222 39.13044 0.283 0 0 0004715 non-membrane spanning protein tyrosine kinase activity F 2 9 12 22.22222 75 2 9 12 22.22222 75 0.283 0 0 0016506 apoptosis activator activity F 1 5 6 20 83.33334 2 9 10 22.22222 90 0.283 0 0 0042168 heme metabolism P 0 0 0 0 0 2 9 15 22.22222 60 0.283 0 0 0006638 neutral lipid metabolism P 0 0 0 0 0 2 9 21 22.22222 42.85714 0.283 0 0 0006779 porphyrin biosynthesis P 0 1 2 0 50 2 9 16 22.22222 56.25 0.283 0 0 0005003 ephrin receptor activity F 2 6 14 33.33333 42.85714 2 9 19 22.22222 47.36842 0.283 0 0 0006662 glycerol ether metabolism P 0 0 0 0 0 2 9 21 22.22222 42.85714 0.283 0 0 0046486 glycerolipid metabolism P 0 0 0 0 0 2 9 21 22.22222 42.85714 0.283 0 0 0006639 acylglycerol metabolism P 0 0 0 0 0 2 9 21 22.22222 42.85714 0.283 0 0 0016504 protease activator activity F 0 0 0 0 0 2 9 9 22.22222 100 0.283 0 0 0005741 mitochondrial outer membrane C 3 13 33 23.07692 39.39394 3 14 35 21.42857 40 0.277 0 0 0016645 oxidoreductase activity\, acting on the CH-NH group of donors F 0 0 0 0 0 3 14 30 21.42857 46.66667 0.277 0 0 0006289 nucleotide-excision repair P 3 10 20 30 50 3 14 25 21.42857 56 0.277 0 0 0004521 endoribonuclease activity F 0 2 4 0 50 3 14 46 21.42857 30.43478 0.277 0 0 0042401 biogenic amine biosynthesis P 0 0 0 0 0 3 14 20 21.42857 70 0.277 0 0 0003887 DNA-directed DNA polymerase activity F 0 1 4 0 25 3 14 27 21.42857 51.85185 0.277 0 0 0005764 lysosome C 14 69 83 20.28986 83.13253 15 76 91 19.73684 83.51649 0.267 0 0 0000323 lytic vacuole C 0 0 0 0 0 15 76 91 19.73684 83.51649 0.267 0 0 0005541 acyl-CoA or acyl binding F 0 0 0 0 0 6 30 42 20 71.42857 0.204 0 0 0005803 secretory vesicle C 5 25 34 20 73.52941 5 25 34 20 73.52941 0.187 0 0 0004722 protein serine/threonine phosphatase activity F 0 2 12 0 16.66667 9 46 74 19.56522 62.16216 0.177 0 0 0015711 organic anion transport P 1 9 13 11.11111 69.23077 4 20 33 20 60.60606 0.167 0 0 0006694 steroid biosynthesis P 2 13 21 15.38461 61.90476 8 41 62 19.5122 66.12904 0.159 0 0 0005773 vacuole C 0 1 5 0 20 15 78 98 19.23077 79.59184 0.155 0 0 0005624 membrane fraction C 57 316 416 18.03798 75.96154 72 382 529 18.84817 72.21172 0.153 0 0 0016787 hydrolase activity F 81 515 956 15.72816 53.87029 195 1042 2387 18.71401 43.65312 0.145 0 0 0007128 meiotic prophase I P 0 0 0 0 0 3 15 21 20 71.42857 0.144 0 0 0007127 meiosis I P 0 0 0 0 0 3 15 21 20 71.42857 0.144 0 0 0005247 voltage-gated chloride channel activity F 3 15 23 20 65.21739 3 15 23 20 65.21739 0.144 0 0 0005506 iron ion binding F 2 8 21 25 38.09524 3 15 34 20 44.11765 0.144 0 0 0005813 centrosome C 3 12 17 25 70.58823 3 15 24 20 62.5 0.144 0 0 0006066 alcohol metabolism P 1 5 8 20 62.5 23 121 211 19.00826 57.34597 0.13 0 0 0008028 monocarboxylic acid transporter activity F 0 3 5 0 60 2 10 18 20 55.55556 0.118 0 0 0007584 response to nutrients P 2 10 13 20 76.92308 2 10 13 20 76.92308 0.118 0 0 0005548 phospholipid transporter activity F 0 0 0 0 0 2 10 24 20 41.66667 0.118 0 0 0009991 response to extracellular stimulus P 0 0 0 0 0 2 10 13 20 76.92308 0.118 0 0 0005540 hyaluronic acid binding F 2 10 23 20 43.47826 2 10 23 20 43.47826 0.118 0 0 0005871 kinesin complex C 2 8 15 25 53.33333 2 10 18 20 55.55556 0.118 0 0 0004198 calpain activity F 2 10 13 20 76.92308 2 10 13 20 76.92308 0.118 0 0 0007606 chemosensory perception P 1 2 2 50 100 2 10 328 20 3.04878 0.118 0 0 0007269 neurotransmitter secretion P 1 6 10 16.66667 60 2 10 15 20 66.66666 0.118 0 0 0009636 response to toxin P 2 10 18 20 55.55556 2 10 18 20 55.55556 0.118 0 0 0007173 EGF receptor signaling pathway P 1 6 8 16.66667 75 2 10 12 20 83.33334 0.118 0 0 0004520 endodeoxyribonuclease activity F 0 4 4 0 100 2 10 14 20 71.42857 0.118 0 0 0009593 perception of chemical substance P 0 1 1 0 100 2 10 328 20 3.04878 0.118 0 0 0007031 peroxisome organization and biogenesis P 2 10 11 20 90.90909 2 10 12 20 83.33334 0.118 0 0 0046474 glycerophospholipid biosynthesis P 0 0 0 0 0 2 10 14 20 71.42857 0.118 0 0 0003893 epsilon DNA polymerase activity F 2 10 16 20 62.5 2 10 16 20 62.5 0.118 0 0 0030135 coated vesicle C 0 1 2 0 50 6 31 83 19.35484 37.3494 0.115 0 0 0016740 transferase activity F 115 562 1146 20.46263 49.04014 153 819 1783 18.68132 45.93382 0.101 0 0 0006473 protein amino acid acetylation P 0 2 2 0 100 1 5 5 20 100 0.083 0 0 0004017 adenylate kinase activity F 1 5 6 20 83.33334 1 5 6 20 83.33334 0.083 0 0 0004861 cyclin-dependent protein kinase inhibitor activity F 1 5 9 20 55.55556 1 5 9 20 55.55556 0.083 0 0 0018193 peptidyl-amino acid modification P 0 0 0 0 0 1 5 9 20 55.55556 0.083 0 0 0016986 transcription initiation factor activity F 1 5 7 20 71.42857 1 5 7 20 71.42857 0.083 0 0 0015198 oligopeptide transporter activity F 1 5 6 20 83.33334 1 5 6 20 83.33334 0.083 0 0 0016840 carbon-nitrogen lyase activity F 0 0 0 0 0 1 5 6 20 83.33334 0.083 0 0 0016307 phosphatidylinositol phosphate kinase activity F 0 0 0 0 0 1 5 16 20 31.25 0.083 0 0 0000049 tRNA binding F 1 5 10 20 50 1 5 10 20 50 0.083 0 0 0005890 sodium/potassium-exchanging ATPase complex C 1 5 7 20 71.42857 1 5 7 20 71.42857 0.083 0 0 0008625 induction of apoptosis via death domain receptors P 1 5 8 20 62.5 1 5 8 20 62.5 0.083 0 0 0006312 mitotic recombination P 0 2 3 0 66.66666 1 5 7 20 71.42857 0.083 0 0 0017149 protein biosynthesis inhibitor activity F 1 5 5 20 100 1 5 5 20 100 0.083 0 0 0019885 antigen processing\, endogenous antigen via MHC class I P 1 5 17 20 29.41176 1 5 17 20 29.41176 0.083 0 0 0016303 phosphatidylinositol 3-kinase activity F 1 5 13 20 38.46154 1 5 13 20 38.46154 0.083 0 0 0005929 cilium C 0 2 3 0 66.66666 1 5 13 20 38.46154 0.083 0 0 0006942 regulation of striated muscle contraction P 1 5 8 20 62.5 1 5 8 20 62.5 0.083 0 0 0008272 sulfate transport P 1 5 21 20 23.80952 1 5 21 20 23.80952 0.083 0 0 0006825 copper ion transport P 1 4 6 25 66.66666 1 5 7 20 71.42857 0.083 0 0 0006265 DNA topological change P 1 5 8 20 62.5 1 5 8 20 62.5 0.083 0 0 0004645 phosphorylase activity F 1 2 5 50 40 1 5 8 20 62.5 0.083 0 0 0035004 phosphoinositide 3-kinase activity F 0 0 0 0 0 1 5 13 20 38.46154 0.083 0 0 0016012 sarcoglycan complex C 1 5 6 20 83.33334 1 5 6 20 83.33334 0.083 0 0 0005906 clathrin adaptor C 1 5 6 20 83.33334 1 5 6 20 83.33334 0.083 0 0 0016624 oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, disulfide as acceptor F 0 1 5 0 20 1 5 11 20 45.45454 0.083 0 0 0006359 regulation of transcription from Pol III promoter P 1 5 6 20 83.33334 1 5 6 20 83.33334 0.083 0 0 0045239 TCA cycle enzyme complex C 0 1 1 0 100 1 5 6 20 83.33334 0.083 0 0 0006044 N-acetylglucosamine metabolism P 0 2 5 0 40 1 5 8 20 62.5 0.083 0 0 0005248 voltage-gated sodium channel activity F 1 5 15 20 33.33333 1 5 15 20 33.33333 0.083 0 0 0006368 RNA elongation from Pol II promoter P 1 5 5 20 100 1 5 5 20 100 0.083 0 0 0042136 neurotransmitter biosynthesis P 1 3 4 33.33333 75 1 5 7 20 71.42857 0.083 0 0 0016011 dystroglycan complex C 0 0 0 0 0 1 5 6 20 83.33334 0.083 0 0 0042575 DNA polymerase complex C 0 0 0 0 0 1 5 7 20 71.42857 0.083 0 0 0006929 substrate-bound cell migration P 0 2 2 0 100 1 5 6 20 83.33334 0.083 0 0 0007015 actin filament organization P 1 5 7 20 71.42857 1 5 7 20 71.42857 0.083 0 0 0016873 other isomerase activity F 0 0 0 0 0 1 5 9 20 55.55556 0.083 0 0 0003916 DNA topoisomerase activity F 0 0 1 0 0 1 5 9 20 55.55556 0.083 0 0 0003780 actin cross-linking activity F 1 5 8 20 62.5 1 5 8 20 62.5 0.083 0 0 0003841 1-acylglycerol-3-phosphate O-acyltransferase activity F 1 5 5 20 100 1 5 5 20 100 0.083 0 0 0005798 Golgi vesicle C 1 3 4 33.33333 75 1 5 12 20 41.66667 0.083 0 0 0045664 regulation of neuron differentiation P 1 5 5 20 100 1 5 5 20 100 0.083 0 0 0004653 polypeptide N-acetylgalactosaminyltransferase activity F 1 5 8 20 62.5 1 5 8 20 62.5 0.083 0 0 0009110 vitamin biosynthesis P 0 1 1 0 100 1 5 9 20 55.55556 0.083 0 0 0019104 DNA N-glycosylase activity F 0 0 1 0 0 1 5 10 20 50 0.083 0 0 0016567 protein ubiquitination P 1 4 15 25 26.66667 1 5 17 20 29.41176 0.083 0 0 0016409 palmitoyltransferase activity F 0 0 0 0 0 1 5 5 20 100 0.083 0 0 0004895 cell adhesion receptor activity F 6 32 62 18.75 51.6129 6 32 62 18.75 51.6129 0.029 0 0 0042398 amino acid derivative biosynthesis P 0 0 0 0 0 3 16 23 18.75 69.56522 0.02 0 0 0007249 NIK-I-kappaB/NF-kappaB cascade P 1 5 10 20 50 3 16 26 18.75 61.53846 0.02 0 0 GO Gene Ontology r 0 0 0 0 0 1297 6991 17564 18.55243 39.80301 0 0 0 0001505 regulation of neurotransmitter levels P 1 2 2 50 100 5 27 38 18.51852 71.05264 -0.005 0 0 0005941 unlocalized C 0 0 0 0 0 7 38 72 18.42105 52.77778 -0.021 0 0 0006635 fatty acid beta-oxidation P 2 11 14 18.18182 78.57143 2 11 14 18.18182 78.57143 -0.032 0 0 0006919 caspase activation P 2 8 9 25 88.88889 2 11 13 18.18182 84.61539 -0.032 0 0 0030551 cyclic nucleotide binding F 0 0 0 0 0 2 11 17 18.18182 64.70588 -0.032 0 0 0007611 learning and/or memory P 1 9 11 11.11111 81.81818 2 11 14 18.18182 78.57143 -0.032 0 0 0045761 regulation of adenylate cyclase activity P 0 0 0 0 0 2 11 14 18.18182 78.57143 -0.032 0 0 0008513 organic cation porter activity F 0 1 1 0 100 2 11 18 18.18182 61.11111 -0.032 0 0 0007194 negative regulation of adenylate cyclase activity P 2 11 14 18.18182 78.57143 2 11 14 18.18182 78.57143 -0.032 0 0 0016283 eukaryotic 48S initiation complex C 0 0 0 0 0 4 22 30 18.18182 73.33334 -0.045 0 0 0005843 cytosolic small ribosomal subunit (sensu Eukarya) C 4 22 30 18.18182 73.33334 4 22 30 18.18182 73.33334 -0.045 0 0 0006576 biogenic amine metabolism P 0 1 1 0 100 4 22 38 18.18182 57.89474 -0.045 0 0 0005977 glycogen metabolism P 2 10 12 20 83.33334 4 22 26 18.18182 84.61539 -0.045 0 0 0008305 integrin complex C 4 22 47 18.18182 46.80851 4 22 47 18.18182 46.80851 -0.045 0 0 0004221 ubiquitin thiolesterase activity F 4 22 75 18.18182 29.33333 4 22 75 18.18182 29.33333 -0.045 0 0 0007149 colony morphology P 0 0 0 0 0 4 22 26 18.18182 84.61539 -0.045 0 0 0006073 glucan metabolism P 0 0 0 0 0 4 22 27 18.18182 81.48148 -0.045 0 0 0008170 N-methyltransferase activity F 2 11 29 18.18182 37.93103 4 22 48 18.18182 45.83333 -0.045 0 0 0007125 invasive growth P 4 22 26 18.18182 84.61539 4 22 26 18.18182 84.61539 -0.045 0 0 0009063 amino acid catabolism P 0 0 0 0 0 6 33 48 18.18182 68.75 -0.055 0 0 0009310 amine catabolism P 0 0 0 0 0 6 33 48 18.18182 68.75 -0.055 0 0 0006519 amino acid and derivative metabolism P 1 2 2 50 100 23 126 208 18.25397 60.57692 -0.087 0 0 0030136 clathrin-coated vesicle C 0 0 1 0 0 5 28 76 17.85714 36.84211 -0.095 0 0 0042440 pigment metabolism P 0 0 0 0 0 3 17 24 17.64706 70.83334 -0.096 0 0 0007266 Rho protein signal transduction P 3 17 19 17.64706 89.47369 3 17 19 17.64706 89.47369 -0.096 0 0 0005815 microtubule organizing center C 0 1 1 0 100 3 17 27 17.64706 62.96296 -0.096 0 0 0008277 regulation of G-protein coupled receptor protein signaling pathway P 3 17 23 17.64706 73.91304 3 17 23 17.64706 73.91304 -0.096 0 0 0009405 pathogenesis P 9 48 65 18.75 73.84615 9 50 67 18 74.62687 -0.101 0 0 0006917 induction of apoptosis P 5 44 62 11.36364 70.96774 13 72 107 18.05556 67.28972 -0.109 0 0 0006820 anion transport P 4 12 36 33.33333 33.33333 13 72 143 18.05556 50.34965 -0.109 0 0 0012502 induction of programmed cell death P 0 0 0 0 0 13 72 107 18.05556 67.28972 -0.109 0 0 0005942 phosphoinositide 3-kinase complex C 1 6 15 16.66667 40 1 6 15 16.66667 40 -0.119 0 0 0008199 ferric iron binding F 1 6 12 16.66667 50 1 6 12 16.66667 50 -0.119 0 0 0007214 gamma-aminobutyric acid signaling pathway P 1 6 15 16.66667 40 1 6 15 16.66667 40 -0.119 0 0 0009311 oligosaccharide metabolism P 0 4 4 0 100 1 6 6 16.66667 100 -0.119 0 0 0004463 leukotriene-A4 hydrolase activity F 0 0 0 0 0 1 6 10 16.66667 60 -0.119 0 0 0016803 ether hydrolase activity F 0 0 0 0 0 1 6 10 16.66667 60 -0.119 0 0 0006700 C21-steroid hormone biosynthesis P 1 6 8 16.66667 75 1 6 9 16.66667 66.66666 -0.119 0 0 0008376 acetylgalactosaminyltransferase activity F 0 0 0 0 0 1 6 10 16.66667 60 -0.119 0 0 0007608 olfaction P 1 6 319 16.66667 1.880878 1 6 319 16.66667 1.880878 -0.119 0 0 0004467 long-chain-fatty-acid-CoA ligase activity F 1 6 8 16.66667 75 1 6 8 16.66667 75 -0.119 0 0 0006760 folic acid and derivative metabolism P 0 0 0 0 0 1 6 9 16.66667 66.66666 -0.119 0 0 0008207 C21-steroid hormone metabolism P 0 0 0 0 0 1 6 9 16.66667 66.66666 -0.119 0 0 0007250 activation of NF-kappaB-inducing kinase P 1 6 10 16.66667 60 1 6 10 16.66667 60 -0.119 0 0 0005523 tropomyosin binding F 1 6 14 16.66667 42.85714 1 6 14 16.66667 42.85714 -0.119 0 0 0016181 synaptic vesicle transport P 0 0 1 0 0 1 6 8 16.66667 75 -0.119 0 0 0005833 hemoglobin complex C 1 6 16 16.66667 37.5 1 6 16 16.66667 37.5 -0.119 0 0 0016032 viral life cycle P 0 2 10 0 20 1 6 19 16.66667 31.57895 -0.119 0 0 0005802 Golgi trans face C 1 6 9 16.66667 66.66666 1 6 9 16.66667 66.66666 -0.119 0 0 0009881 photoreceptor activity F 0 0 0 0 0 1 6 11 16.66667 54.54546 -0.119 0 0 0004385 guanylate kinase activity F 1 6 10 16.66667 60 1 6 10 16.66667 60 -0.119 0 0 0006583 melanin biosynthesis from tyrosine P 1 6 6 16.66667 100 1 6 6 16.66667 100 -0.119 0 0 0006582 melanin metabolism P 0 0 0 0 0 1 6 6 16.66667 100 -0.119 0 0 0042438 melanin biosynthesis P 0 0 0 0 0 1 6 6 16.66667 100 -0.119 0 0 0006857 oligopeptide transport P 1 6 12 16.66667 50 1 6 12 16.66667 50 -0.119 0 0 0003709 RNA polymerase III transcription factor activity F 1 6 7 16.66667 85.71429 1 6 7 16.66667 85.71429 -0.119 0 0 0006379 mRNA cleavage P 1 6 6 16.66667 100 1 6 6 16.66667 100 -0.119 0 0 0005391 sodium/potassium-exchanging ATPase activity F 1 6 11 16.66667 54.54546 1 6 11 16.66667 54.54546 -0.119 0 0 0015175 neutral amino acid transporter activity F 1 4 4 25 100 1 6 7 16.66667 85.71429 -0.119 0 0 0016411 acylglycerol O-acyltransferase activity F 0 0 0 0 0 1 6 6 16.66667 100 -0.119 0 0 0005311 sodium\:dicarboxylate/tricarboxylate symporter activity F 1 6 9 16.66667 66.66666 1 6 9 16.66667 66.66666 -0.119 0 0 0008020 G-protein coupled photoreceptor activity F 1 6 11 16.66667 54.54546 1 6 11 16.66667 54.54546 -0.119 0 0 0004301 epoxide hydrolase activity F 1 6 10 16.66667 60 1 6 10 16.66667 60 -0.119 0 0 0004726 non-membrane spanning protein tyrosine phosphatase activity F 1 6 9 16.66667 66.66666 1 6 9 16.66667 66.66666 -0.119 0 0 0007257 activation of JUNK P 1 6 8 16.66667 75 1 6 8 16.66667 75 -0.119 0 0 0009081 branched chain family amino acid metabolism P 0 0 0 0 0 1 6 8 16.66667 75 -0.119 0 0 0006817 phosphate transport P 1 6 9 16.66667 66.66666 1 6 9 16.66667 66.66666 -0.119 0 0 0015197 peptide transporter activity F 0 0 0 0 0 1 6 9 16.66667 66.66666 -0.119 0 0 0008570 myosin ATPase activity F 1 6 8 16.66667 75 1 6 8 16.66667 75 -0.119 0 0 0015645 fatty-acid ligase activity F 0 0 0 0 0 1 6 8 16.66667 75 -0.119 0 0 0015833 peptide transport P 0 1 2 0 50 1 6 14 16.66667 42.85714 -0.119 0 0 0006402 mRNA catabolism P 0 3 5 0 60 1 6 8 16.66667 75 -0.119 0 0 0015354 polyspecific organic cation transporter activity F 0 0 0 0 0 1 6 9 16.66667 66.66666 -0.119 0 0 0015142 tricarboxylic acid transporter activity F 0 0 0 0 0 1 6 10 16.66667 60 -0.119 0 0 0007422 peripheral nervous system development P 1 5 11 20 45.45454 1 6 12 16.66667 50 -0.119 0 0 0006520 amino acid metabolism P 3 38 58 7.894737 65.51724 19 105 172 18.09524 61.04651 -0.121 0 0 0045786 negative regulation of cell cycle P 7 43 66 16.27907 65.15151 8 45 69 17.77778 65.21739 -0.134 0 0 0016746 transferase activity\, transferring acyl groups F 0 0 0 0 0 12 67 125 17.91045 53.6 -0.136 0 0 0004519 endonuclease activity F 3 19 35 15.78947 54.28571 6 34 77 17.64706 44.15585 -0.136 0 0 0006665 sphingolipid metabolism P 2 4 6 50 66.66666 4 23 34 17.3913 67.64706 -0.143 0 0 0005096 GTPase activator activity F 9 53 80 16.98113 66.25 11 62 104 17.74194 59.61538 -0.165 0 0 0042133 neurotransmitter metabolism P 1 3 5 33.33333 60 2 12 18 16.66667 66.66666 -0.168 0 0 0007389 pattern specification P 0 2 3 0 66.66666 2 12 17 16.66667 70.58823 -0.168 0 0 0019900 kinase binding F 0 0 0 0 0 2 12 17 16.66667 70.58823 -0.168 0 0 0016709 oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, NAD or NADH as one donor\, and incorporation of one atom of oxygen F 0 0 0 0 0 2 12 21 16.66667 57.14286 -0.168 0 0 0006909 phagocytosis P 1 6 8 16.66667 75 2 12 16 16.66667 75 -0.168 0 0 0001727 lipid kinase activity F 0 0 0 0 0 2 12 31 16.66667 38.70968 -0.168 0 0 0019901 protein kinase binding F 1 5 7 20 71.42857 2 12 17 16.66667 70.58823 -0.168 0 0 0006839 mitochondrial transport P 2 12 14 16.66667 85.71429 2 12 17 16.66667 70.58823 -0.168 0 0 0004623 phospholipase A2 activity F 2 12 26 16.66667 46.15385 2 12 27 16.66667 44.44444 -0.168 0 0 0042113 B-cell activation P 1 2 4 50 50 2 12 19 16.66667 63.15789 -0.168 0 0 0016831 carboxy-lyase activity F 0 0 5 0 0 2 12 23 16.66667 52.17391 -0.168 0 0 0005543 phospholipid binding F 0 10 14 0 71.42857 5 29 37 17.24138 78.37838 -0.182 0 0 0005976 polysaccharide metabolism P 0 2 2 0 100 5 29 44 17.24138 65.90909 -0.182 0 0 0004540 ribonuclease activity F 1 5 12 20 41.66667 3 18 66 16.66667 27.27273 -0.206 0 0 0006937 regulation of muscle contraction P 2 11 13 18.18182 84.61539 3 18 27 16.66667 66.66666 -0.206 0 0 0000139 Golgi membrane C 3 12 22 25 54.54546 3 18 31 16.66667 58.06452 -0.206 0 0 0048066 pigmentation P 0 0 0 0 0 3 18 25 16.66667 72 -0.206 0 0 0008203 cholesterol metabolism P 0 20 31 0 64.51613 6 35 52 17.14286 67.30769 -0.215 0 0 0000041 transition metal ion transport P 0 0 0 0 0 4 24 35 16.66667 68.57143 -0.238 0 0 0004197 cysteine-type endopeptidase activity F 5 30 104 16.66667 28.84615 10 58 146 17.24138 39.72603 -0.258 0 0 0042579 microbody C 0 0 0 0 0 8 47 62 17.02128 75.80645 -0.271 0 0 0005777 peroxisome C 8 40 56 20 71.42857 8 47 65 17.02128 72.30769 -0.271 0 0 0016329 apoptosis regulator activity F 3 34 70 8.823529 48.57143 13 75 127 17.33333 59.05512 -0.273 0 0 0016747 transferase activity\, transferring groups other than amino-acyl groups F 0 0 0 0 0 11 64 114 17.1875 56.14035 -0.282 0 0 0008415 acyltransferase activity F 8 48 81 16.66667 59.25926 11 64 113 17.1875 56.63717 -0.282 0 0 0006672 ceramide metabolism P 1 4 4 25 100 1 7 8 14.28571 87.5 -0.291 0 0 0008656 caspase activator activity F 1 7 7 14.28571 100 1 7 7 14.28571 100 -0.291 0 0 0005315 inorganic phosphate transporter activity F 1 0 2 0 0 1 7 13 14.28571 53.84615 -0.291 0 0 0005158 insulin receptor binding F 1 7 15 14.28571 46.66667 1 7 15 14.28571 46.66667 -0.291 0 0 0005388 calcium-transporting ATPase activity F 1 7 10 14.28571 70 1 7 10 14.28571 70 -0.291 0 0 0043028 caspase regulator activity F 0 0 0 0 0 1 7 7 14.28571 100 -0.291 0 0 0006835 dicarboxylic acid transport P 1 6 10 16.66667 60 1 7 11 14.28571 63.63636 -0.291 0 0 0006094 gluconeogenesis P 1 6 12 16.66667 50 1 7 14 14.28571 50 -0.291 0 0 0046466 membrane lipid catabolism P 0 0 0 0 0 1 7 13 14.28571 53.84615 -0.291 0 0 0007456 eye morphogenesis (sensu Drosophila) P 1 5 6 20 83.33334 1 7 10 14.28571 70 -0.291 0 0 0005310 dicarboxylic acid transporter activity F 0 0 1 0 0 1 7 11 14.28571 63.63636 -0.291 0 0 0019212 phosphatase inhibitor activity F 0 0 1 0 0 1 7 15 14.28571 46.66667 -0.291 0 0 0016500 protein-hormone receptor activity F 1 2 5 50 40 1 7 12 14.28571 58.33333 -0.291 0 0 0008131 amine oxidase activity F 0 0 0 0 0 1 7 8 14.28571 87.5 -0.291 0 0 0005765 lysosomal membrane C 1 7 8 14.28571 87.5 1 7 8 14.28571 87.5 -0.291 0 0 0006783 heme biosynthesis P 1 7 13 14.28571 53.84615 1 7 13 14.28571 53.84615 -0.291 0 0 0016883 other carbon-nitrogen ligase activity F 0 0 0 0 0 1 7 19 14.28571 36.84211 -0.291 0 0 0004864 protein phosphatase inhibitor activity F 1 5 10 20 50 1 7 14 14.28571 50 -0.291 0 0 0005779 integral to peroxisomal membrane C 1 7 11 14.28571 63.63636 1 7 11 14.28571 63.63636 -0.291 0 0 0006284 base-excision repair P 1 7 12 14.28571 58.33333 1 7 12 14.28571 58.33333 -0.291 0 0 0019395 fatty acid oxidation P 0 0 0 0 0 2 13 17 15.38461 76.47059 -0.294 0 0 0004860 protein kinase inhibitor activity F 1 5 7 20 71.42857 2 13 22 15.38461 59.09091 -0.294 0 0 0015103 inorganic anion transporter activity F 0 0 0 0 0 2 13 51 15.38461 25.4902 -0.294 0 0 0007190 adenylate cyclase activation P 2 13 17 15.38461 76.47059 2 13 17 15.38461 76.47059 -0.294 0 0 0009790 embryonic development P 1 3 9 33.33333 33.33333 2 13 30 15.38461 43.33333 -0.294 0 0 0005905 coated pit C 3 19 30 15.78947 63.33333 3 19 30 15.78947 63.33333 -0.31 0 0 0016477 cell migration P 0 0 6 0 0 3 19 36 15.78947 52.77778 -0.31 0 0 0016023 cytoplasmic vesicle C 0 3 5 0 60 7 42 102 16.66667 41.17647 -0.315 0 0 0016459 myosin C 3 23 62 13.04348 37.09678 4 25 67 16 37.31343 -0.329 0 0 0008372 cellular_component unknown C 67 376 923 17.81915 40.73673 67 376 923 17.81915 40.73673 -0.376 0 0 0006812 cation transport P 6 79 203 7.594937 38.91626 43 244 539 17.62295 45.26902 -0.38 0 0 0016757 transferase activity\, transferring glycosyl groups F 13 84 146 15.47619 57.53425 19 111 237 17.11712 46.83544 -0.392 0 0 0008284 positive regulation of cell proliferation P 11 63 108 17.46032 58.33333 11 66 114 16.66667 57.89474 -0.396 0 0 0042981 regulation of apoptosis P 0 0 0 0 0 22 128 184 17.1875 69.56522 -0.401 0 0 0016712 oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, reduced flavin or flavoprotein as one donor\, and incorporation of one atom of oxygen F 0 0 3 0 0 2 14 28 14.28571 50 -0.411 0 0 0006939 smooth muscle contraction P 2 12 18 16.66667 66.66666 2 14 24 14.28571 58.33333 -0.411 0 0 0007273 regulation of synapse P 1 13 18 7.692307 72.22222 2 14 19 14.28571 73.68421 -0.411 0 0 0046915 transition metal ion transporter activity F 0 0 0 0 0 2 14 15 14.28571 93.33334 -0.411 0 0 0006941 striated muscle contraction P 1 9 23 11.11111 39.13044 2 14 31 14.28571 45.16129 -0.411 0 0 0015457 auxiliary transport protein activity F 1 2 2 50 100 2 14 25 14.28571 56 -0.411 0 0 0050381 unspecific monooxygenase activity F 2 14 25 14.28571 56 2 14 25 14.28571 56 -0.411 0 0 0016627 oxidoreductase activity\, acting on the CH-CH group of donors F 0 0 0 0 0 4 26 41 15.38461 63.41463 -0.416 0 0 0016125 sterol metabolism P 0 0 0 0 0 6 38 59 15.78947 64.40678 -0.439 0 0 0007223 frizzled-2 signaling pathway P 1 8 21 12.5 38.09524 1 8 21 12.5 38.09524 -0.441 0 0 0019370 leukotriene biosynthesis P 1 8 11 12.5 72.72727 1 8 11 12.5 72.72727 -0.441 0 0 0016775 phosphotransferase activity\, nitrogenous group as acceptor F 0 0 0 0 0 1 8 14 12.5 57.14286 -0.441 0 0 0009225 nucleotide-sugar metabolism P 0 3 4 0 75 1 8 10 12.5 80 -0.441 0 0 0008417 fucosyltransferase activity F 0 3 7 0 42.85714 1 8 14 12.5 57.14286 -0.441 0 0 0005859 muscle myosin C 1 8 22 12.5 36.36364 1 8 22 12.5 36.36364 -0.441 0 0 0046651 lymphocyte proliferation P 0 0 0 0 0 1 8 13 12.5 61.53846 -0.441 0 0 0001654 eye morphogenesis P 0 0 0 0 0 1 8 11 12.5 72.72727 -0.441 0 0 0004289 subtilase activity F 1 8 20 12.5 40 1 8 20 12.5 40 -0.441 0 0 0030101 natural killer cell activation P 1 8 10 12.5 80 1 8 10 12.5 80 -0.441 0 0 0016010 dystrophin-associated glycoprotein complex C 0 4 6 0 66.66666 1 8 12 12.5 66.66666 -0.441 0 0 0019888 protein phosphatase regulator activity F 0 0 0 0 0 1 8 16 12.5 50 -0.441 0 0 0016799 hydrolase activity\, hydrolyzing N-glycosyl compounds F 0 0 0 0 0 1 8 13 12.5 61.53846 -0.441 0 0 0000159 protein phosphatase type 2A complex C 1 8 13 12.5 61.53846 1 8 13 12.5 61.53846 -0.441 0 0 0046519 sphingoid metabolism P 0 0 0 0 0 1 8 10 12.5 80 -0.441 0 0 0006629 lipid metabolism P 13 77 129 16.88312 59.68992 56 318 519 17.61006 61.27168 -0.442 0 0 0004261 cathepsin G activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045070 positive regulation of viral genome replication P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046246 terpene biosynthesis P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0008198 ferrous iron binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004325 ferrochelatase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004192 cathepsin D activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004426 indoleamine-pyrrole 2\,3-dioxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004421 hydroxymethylglutaryl-CoA synthase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0015824 L-proline transport P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004216 cathepsin K activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004411 homogentisate 1\,2-dioxygenase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0001532 interleukin-21 receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005369 taurine\:sodium symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016019 peptidoglycan recognition activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0045727 positive regulation of protein biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005598 short-chain collagen C 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0016566 specific transcriptional repressor activity F 0 1 6 0 16.66667 0 1 6 0 16.66667 -0.477 0 0 0015375 glycine\:sodium symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004208 caspase-3 activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005330 dopamine\:sodium symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004655 porphobilinogen synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015886 heme transport P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042289 MHC class II protein binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004894 T-cell receptor activity F 0 1 5 0 20 0 1 5 0 20 -0.477 0 0 0045058 T-cell selection P 0 1 1 0 100 0 1 2 0 50 -0.477 0 0 0045086 positive regulation of interleukin-2 biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004218 cathepsin S activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004203 caspase-4 activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042101 T-cell receptor complex C 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0005309 creatine\:sodium symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004418 hydroxymethylbilane synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0019343 cysteine biosynthesis via cystathione P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015680 intracellular copper ion transport P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006548 histidine catabolism P 0 1 2 0 50 0 1 3 0 33.33333 -0.477 0 0 0009076 histidine family amino acid biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004397 histidine ammonia-lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016517 interleukin-12 receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005335 serotonin\:sodium symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005898 interleukin-13 receptor complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004340 glucokinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042470 melanosome C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045078 positive regulation of interferon-gamma biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0006535 cysteine biosynthesis from serine P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015222 serotonin transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004920 interleukin-10 receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0016573 histone acetylation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004187 carboxypeptidase D activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004122 cystathionine beta-synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004951 cholecystokinin receptor activity F 0 1 1 0 100 0 1 3 0 33.33333 -0.477 0 0 0042214 terpene metabolism P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0050425 carboxypeptidase B activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030346 protein phosphatase 2B binding F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004201 caspase-1 activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042007 interleukin-18 binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003680 AT DNA binding F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0008571 non-chaperonin molecular chaperone ATPase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046539 histamine N-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004810 tRNA adenylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004408 holocytochrome-c synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006837 serotonin transport P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003868 4-hydroxyphenylpyruvate dioxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0019977 interleukin-21 binding F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0048081 positive regulation of cuticle pigmentation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0048075 positive regulation of eye pigmentation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030368 interleukin-17 receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008120 ceramide glucosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006543 glutamine catabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008446 GDP-mannose 4\,6-dehydratase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0000299 integral to membrane of membrane fraction C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0003920 GMP reductase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0009898 internal side of plasma membrane C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006043 glucosamine catabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004342 glucosamine-6-phosphate deaminase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0016534 cyclin-dependent protein kinase 5 activator activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0009853 photorespiration P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0042597 periplasmic space C 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0008455 alpha-1\,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003830 beta-1\,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030144 alpha-1\,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005183 luteinizing hormone-releasing factor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006679 glucosylceramide biosynthesis P 0 1 1 0 100 0 1 2 0 50 -0.477 0 0 0004367 glycerol-3-phosphate dehydrogenase (NAD) activity F 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0004142 diacylglycerol cholinephosphotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004605 phosphatidate cytidylyltransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0015235 vitamin B12 transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015037 peptide disulfide oxidoreductase activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0003840 gamma-glutamyltransferase activity F 0 1 7 0 14.28571 0 1 7 0 14.28571 -0.477 0 0 0004903 growth hormone receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016608 growth hormone-releasing hormone activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0005131 growth hormone receptor binding F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0016519 gastric inhibitory peptide receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0006878 copper ion homeostasis P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0003905 alkylbase DNA N-glycosylase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004323 multicopper ferroxidase iron transport mediator activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0001729 ceramide kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045076 regulation of interleukin-2 biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004416 hydroxyacylglutathione hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003844 1\,4-alpha-glucan branching enzyme activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015038 glutathione disulfide oxidoreductase activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0007080 mitotic metaphase plate congression P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030313 cell envelope C 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0017174 glycine N-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007079 mitotic chromosome movement P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003941 L-serine ammonia-lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003912 DNA nucleotidylexotransferase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0008449 N-acetylglucosamine-6-sulfatase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004231 insulysin activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004368 glycerol-3-phosphate dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008065 establishment of blood/nerve barrier P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009077 histidine family amino acid catabolism P 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0030162 regulation of proteolysis and peptidolysis P 0 1 9 0 11.11111 0 1 9 0 11.11111 -0.477 0 0 0046087 cytidine metabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015755 fructose transport P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005353 fructose transporter activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0030290 sphingolipid activator protein activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030288 periplasmic space (sensu Gram-negative Bacteria) C 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0004373 glycogen (starch) synthase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0042335 cuticle biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0016533 cyclin-dependent protein kinase 5 activator complex C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004205 caspase-8 activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009854 oxidative photosynthetic carbon pathway P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015249 nonselective channel activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0008353 [RNA-polymerase]-subunit kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0019972 interleukin-12 binding F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0005331 gamma-aminobutyric acid transporter activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0019975 interleukin-17 binding F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0019969 interleukin-10 binding F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0042478 regulation of eye photoreceptor development P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005283 sodium\:amino acid transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015055 secretin receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006938 sarcomere alignment P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004277 granzyme A activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004278 granzyme B activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016850 other lyase activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004891 glycine-inhibited chloride channel activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0004968 gonadotropin-releasing hormone receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0048069 eye pigmentation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0048087 positive regulation of pigmentation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0003975 UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0048070 regulation of pigmentation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0048079 regulation of cuticle pigmentation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0048067 cuticle pigmentation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0009402 toxin resistance P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004363 glutathione synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0048073 regulation of eye pigmentation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004362 glutathione-disulfide reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015802 basic amino acid transport P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0000126 transcription factor TFIIIB complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003870 5-aminolevulinate synthase activity F 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0042828 response to pathogen P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0001540 beta-amyloid binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0048156 tau protein binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0047708 biotinidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0048155 S100 alpha binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030188 chaperone regulator activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0046899 nucleoside-triphosphate-adenylate kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003807 plasma kallikrein activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045446 endothelial cell differentiation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008890 glycine C-acetyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030334 regulation of cell migration P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0004681 casein kinase I activity F 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0005956 protein kinase CK2 complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008605 protein kinase CK2\, intrinsic regulator activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008343 adult feeding behavior P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0048143 astrocyte activation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045917 positive regulation of complement activation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030309 poly-N-acetyllactosamine metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0005334 noradrenaline\:sodium symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042829 defense response to pathogen P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0048169 regulation of long-term neuronal synaptic plasticity P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045346 regulation of MHC class II biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0045342 MHC class II biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0000105 histidine biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0050672 negative regulation of lymphocyte proliferation P 0 0 1 0 0 0 1 2 0 50 -0.477 0 0 0004329 formate-tetrahydrofolate ligase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0045428 regulation of nitric oxide biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004488 methylenetetrahydrofolate dehydrogenase (NADP) activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045349 interferon-alpha biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0019979 interleukin-4 binding F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0015378 sodium\:chloride symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007090 regulation of S phase of mitotic cell cycle P 0 1 1 0 100 0 1 2 0 50 -0.477 0 0 0015273 G-protein enhanced inward rectifier potassium channel activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015272 ATP-activated inward rectifier potassium channel activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0048154 S100 beta binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007044 cell-substrate junction assembly P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0048151 hyperphosphorylation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008470 isovaleryl-CoA dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008386 cholesterol monooxygenase (side-chain-cleaving) activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003837 beta-ureidopropionase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045354 regulation of interferon-alpha biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0046716 muscle maintenance P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042273 ribosomal large subunit biogenesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004700 atypical protein kinase C activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0016978 lipoate-protein ligase B activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0000917 barrier septum formation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008460 dTDP-glucose 4\,6-dehydratase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030429 kynureninase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007309 oocyte axis determination P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0030376 ribosome receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030345 structural constituent of tooth enamel F 0 1 6 0 16.66667 0 1 6 0 16.66667 -0.477 0 0 0047150 betaine-homocysteine S-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0019983 interleukin-9 binding F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0006528 asparagine metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004566 beta-glucuronidase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0042435 indole derivative biosynthesis P 0 0 0 0 0 0 1 4 0 25 -0.477 0 0 0004464 leukotriene-C4 synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006803 glutathione conjugation reaction P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0047323 [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009082 branched chain family amino acid biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0016219 GDP-dissociation stimulator activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042552 myelination P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004454 ketohexokinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005991 trehalose metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0000724 double-strand break repair via homologous recombination P 0 1 1 0 100 0 1 2 0 50 -0.477 0 0 0009814 response to pathogen (incompatible interaction) P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0019981 interleukin-6 binding F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0008574 plus-end-directed kinesin ATPase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008595 determination of anterior/posterior axis\, embryo P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0050113 inositol oxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046977 TAP binding F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0004701 diacylglycerol-activated/phospholipid dependent protein kinase C activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0019982 interleukin-7 binding F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0030748 amine N-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004496 mevalonate kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030371 translation repressor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007500 mesoderm cell fate determination P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0045090 retroviral genome replication P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0030147 natriuresis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030146 diuresis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0019959 interleukin-8 binding F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0008423 bleomycin hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004555 alpha\,alpha-trehalase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009053 electron donor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046812 host cell surface binding F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0007350 blastoderm segmentation P 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0007351 regional subdivision P 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0007518 myoblast cell fate determination P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015860 purine nucleoside transport P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009948 anterior/posterior axis specification P 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0003783 barbed-end actin capping activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016096 polyisoprenoid metabolism P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0015211 purine nucleoside transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009241 polyisoprenoid biosynthesis P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0016108 tetraterpenoid metabolism P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0001615 thyrotropin releasing hormone and secretagogue-like receptors activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0005984 disaccharide metabolism P 0 0 1 0 0 0 1 3 0 33.33333 -0.477 0 0 0045540 regulation of cholesterol biosynthesis P 0 1 1 0 100 0 1 3 0 33.33333 -0.477 0 0 0046789 host cell surface receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0048178 negative regulation of hepacyte growth factor biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005517 calmodulin inhibitor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006889 regulation of calcium in ER P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0042130 negative regulation of T-cell proliferation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016109 tetraterpenoid biosynthesis P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0007346 regulation of mitotic cell cycle P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0008635 caspase activation via cytochrome c P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004214 dipeptidyl-peptidase I activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004206 caspase-10 activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004213 cathepsin B activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004096 catalase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006721 terpenoid metabolism P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0005814 centriole C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0030534 adult behavior P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0000578 embryonic axis specification P 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0007635 chemosensory behavior P 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0045347 negative regulation of MHC class II biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0000725 recombinational repair P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0016116 carotenoid metabolism P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0016117 carotenoid biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004452 isopentenyl-diphosphate delta-isomerase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004423 iduronate-2-sulfatase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016114 terpenoid biosynthesis P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0009952 anterior/posterior pattern formation P 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0015361 low affinity sodium\:dicarboxylate symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005586 collagen type III C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004917 interleukin-7 receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0005585 collagen type II C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005153 interleukin-8 receptor binding F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0045091 regulation of retroviral genome replication P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030593 neutrophil chemotaxis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042119 neutrophil activation P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004918 interleukin-8 receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004919 interleukin-9 receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005138 interleukin-6 receptor binding F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0015927 trehalase activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0046352 disaccharide catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0048176 regulation of hepacyte growth factor biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0048175 hepatocyte growth factor biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004943 C3a anaphylatoxin receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005133 interferon-gamma receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004876 complement component C3a receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004211 caspase-9 activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005140 interleukin-9 receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030307 positive regulation of cell growth P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004441 inositol-1\,4-bisphosphate 1-phosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005141 interleukin-10 receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045355 negative regulation of interferon-alpha biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042033 chemokine biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004092 carnitine O-acetyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042253 granulocyte macrophage colony-stimulating factor biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005588 collagen type V C 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0005582 collagen type XV C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005139 interleukin-7 receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005595 collagen type XII C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004915 interleukin-6 receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0045518 interleukin-22 receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005592 collagen type XI C 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0005135 interleukin-3 receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005136 interleukin-4 receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045189 connective tissue growth factor biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004913 interleukin-4 receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0005591 collagen type VIII C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009626 hypersensitive response P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045019 negative regulation of nitric oxide biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005134 interleukin-2 receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009409 response to cold P 0 1 3 0 33.33333 0 1 4 0 25 -0.477 0 0 0006646 phosphatidylethanolamine biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030659 cytoplasmic vesicle membrane C 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0008211 glucocorticoid metabolism P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0016639 oxidoreductase activity\, acting on the CH-NH2 group of donors\, NAD or NADP as acceptor F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0004137 deoxycytidine kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046653 tetrahydrofolate metabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030389 fructosamine metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004398 histidine decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0010002 cardioblast differentiation P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0006597 spermine biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004821 histidine-tRNA ligase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0016287 glycerone-phosphate O-acyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005106 ephrin F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0017137 Rab interactor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0050031 L-pipecolate oxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005055 laminin receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0009397 folic acid and derivative catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0007195 dopamine receptor\, adenylate cyclase inhibiting pathway P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003812 alternative-complement-pathway C3/C5 convertase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004014 adenosylmethionine decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015372 glutamate/aspartate\:sodium symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045787 positive regulation of cell cycle P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0006059 hexitol metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0019400 alditol metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004694 eukaryotic translation initiation factor 2alpha kinase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0045840 positive regulation of mitosis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0045993 negative regulation of translational initiation by iron P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046777 autophosphorylation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046986 negative regulation of hemoglobin biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042310 vasoconstriction P 0 1 2 0 50 0 1 3 0 33.33333 -0.477 0 0 0004058 aromatic-L-amino-acid decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004912 interleukin-3 receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0001708 cell fate specification P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0015810 L-aspartate transport P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015600 glutamate/aspartate porter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030567 prothrombin activator activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004769 steroid delta-isomerase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004132 dCMP deaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0047750 cholestenol delta-isomerase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016486 peptide hormone processing P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0020037 heme binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005012 Neu/ErbB-2 receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030526 granulocyte macrophage colony-stimulating factor receptor complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006656 phosphatidylcholine biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004900 erythropoietin receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006429 leucyl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046586 regulation of calcium-dependent cell-cell adhesion P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0050613 delta14-sterol reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0000254 C-4 methyl sterol oxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008215 spermine metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0003998 acylphosphatase activity F 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0030030 cell projection organization and biogenesis P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0017075 syntaxin-1 binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004832 valine-tRNA ligase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0006438 valyl-tRNA aminoacylation P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0030031 cell projection biogenesis P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0016149 translation release factor activity\, codon specific F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0019978 interleukin-3 binding F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0004506 squalene monooxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0000250 lanosterol synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005618 cell wall C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004059 aralkylamine N-acetyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042624 ATPase activity\, uncoupled F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004281 pancreatic elastase II activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0009256 10-formyltetrahydrofolate metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0009109 coenzyme catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0008074 guanylate cyclase complex\, soluble C 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0008115 sarcosine oxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0017172 cysteine dioxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046399 glucuronate biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0006427 histidyl-tRNA aminoacylation P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004105 choline-phosphate cytidylyltransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0045629 negative regulation of T-helper 2 cell differentiation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042490 mechanoreceptor differentiation P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0006256 UDP catabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016882 cyclo-ligase activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0009968 negative regulation of signal transduction P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004772 sterol O-acyltransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004439 phosphoinositide 5-phosphatase activity F 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0004823 leucine-tRNA ligase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004275 enteropeptidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007321 sperm displacement P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045627 positive regulation of T-helper 1 cell differentiation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008326 site-specific DNA-methyltransferase (cytosine-specific) activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008670 2\,4-dienoyl-CoA reductase (NADPH) activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009193 pyrimidine ribonucleoside diphosphate metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0042472 inner ear morphogenesis P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0006244 pyrimidine nucleotide catabolism P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0004155 6\,7-dihydropteridine reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006134 dihydrobiopterin reduction P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042475 odontogenesis (sensu Vertebrata) P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006704 glucocorticoid biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0005062 hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004353 glutamate dehydrogenase [NAD(P)] activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0015406 ABC-type uptake permease activity F 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0047021 15-hydroxyprostaglandin dehydrogenase (NADP) activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0050221 prostaglandin-E2 9-reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009140 pyrimidine nucleoside diphosphate catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0009195 pyrimidine ribonucleoside diphosphate catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0005711 meiotic chromosome C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0030302 deoxynucleotide transport P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030233 deoxynucleotide transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046984 regulation of hemoglobin biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0009912 hair cell fate commitment P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0046048 UDP metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0009132 nucleoside diphosphate metabolism P 0 0 0 0 0 0 1 5 0 20 -0.477 0 0 0009185 ribonucleoside diphosphate metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0030347 syntaxin-2 binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009134 nucleoside diphosphate catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0008132 pancreatic elastase activity F 0 0 1 0 0 0 1 5 0 20 -0.477 0 0 0046335 ethanolamine biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0006580 ethanolamine metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0006060 sorbitol metabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009222 pyrimidine ribonucleotide catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0046337 phosphatidylethanolamine metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004250 aminopeptidase I activity F 0 1 5 0 20 0 1 5 0 20 -0.477 0 0 0009138 pyrimidine nucleoside diphosphate metabolism P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0035050 embryonic heart tube development P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0035051 cardiac cell differentiation P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0012506 vesicle membrane C 0 0 0 0 0 0 1 5 0 20 -0.477 0 0 0015424 amino acid-transporting ATPase activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0015646 permease activity F 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0015563 uptake permease activity F 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0015426 polar-amino-acid-transporting ATPase activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0003939 L-iditol 2-dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030071 regulation of mitotic metaphase/anaphase transition P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0017039 dipeptidyl-peptidase III activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004144 diacylglycerol O-acyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006419 alanyl-tRNA aminoacylation P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0008481 sphinganine kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006669 sphinganine-1-phosphate biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009913 epidermal cell differentiation P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0016870 intramolecular transferase activity\, transferring other groups F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0007274 neuromuscular synaptic transmission P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0000012 single strand break repair P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004813 alanine-tRNA ligase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0015781 pyrimidine nucleotide-sugar transport P 0 0 0 0 0 0 1 4 0 25 -0.477 0 0 0007063 regulation of sister chromatid cohesion P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0042586 peptide deformylase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042491 hair cell differentiation P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0008463 formylmethionine deformylase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007447 imaginal disc pattern formation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009446 putrescine biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008783 agmatinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045875 negative regulation of sister chromatid cohesion P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004537 caspase-activated deoxyribonuclease activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0007538 primary sex determination P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042471 ear morphogenesis P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0009450 aminobutyrate catabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045947 negative regulation of translational initiation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004777 succinate-semialdehyde dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004500 dopamine beta-monooxygenase activity F 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0006447 regulation of translational initiation by iron P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0046906 tetrapyrrole binding F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0006703 estrogen biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0007503 fat body development P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016855 racemase and epimerase activity\, acting on amino acids and derivatives F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0016035 zeta DNA polymerase complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016343 cytoskeletal anchoring activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0000232 nuclear interphase chromosome C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0017015 regulation of TGFbeta receptor signaling pathway P 0 1 1 0 100 0 1 2 0 50 -0.477 0 0 0006862 nucleotide transport P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0004027 alcohol sulfotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004304 estrone sulfotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005760 gamma DNA polymerase complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046692 sperm competition P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0008426 protein kinase C inhibitor activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0030238 male sex determination P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004346 glucose-6-phosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0017147 Wnt-protein binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015095 magnesium ion transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007164 establishment of tissue polarity P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0016225 cysteine desulfhydrase activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0030047 actin modification P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016902 oxidoreductase activity\, acting on the CH-OH group of donors\, other acceptors F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0003829 beta-1\,3-galactosyl-O-glycosyl-glycoprotein beta-1\,6-N-acetylglucosaminyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006010 glucose 6-phosphate utilization P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003828 alpha-N-acetylneuraminate alpha-2\,8-sialyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0047936 glucose 1-dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046588 negative regulation of calcium-dependent cell-cell adhesion P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0017080 sodium channel regulator activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045298 tubulin C 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0004647 phosphoserine phosphatase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0042267 natural killer cell mediated cytolysis P 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0003867 4-aminobutyrate transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0000334 3-hydroxyanthranilate 3\,4-dioxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016925 protein sumoylation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008622 epsilon DNA polymerase complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008987 quinolinate synthetase A activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006106 fumarate metabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045842 positive regulation of mitotic metaphase/anaphase transition P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046332 SMAD binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004963 follicle stimulating hormone receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009258 10-formyltetrahydrofolate catabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016155 formyltetrahydrofolate dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015942 formate metabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030272 5-formyltetrahydrofolate cyclo-ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045159 myosin II binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0047291 lactosylceramide alpha-2\,3-sialyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003982 UTP-hexose-1-phosphate uridylyltransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004276 furin activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008107 galactoside 2-alpha-L-fucosyltransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0016657 oxidoreductase activity\, acting on NADH or NADPH\, nitrogenous group as acceptor F 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0003835 beta-galactoside alpha-2\,6-sialyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046348 amino sugar catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0000109 nucleotide excision repair complex C 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0030033 microvillus assembly P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045296 cadherin binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004333 fumarate hydratase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008368 Gram-negative bacterial binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045322 unmethylated CpG binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006678 glucosylceramide metabolism P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0004135 amylo-alpha-1\,6-glucosidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004134 4-alpha-glucanotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005957 debranching enzyme C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007141 male meiosis I P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003784 barbed-end actin capping/severing activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042462 eye photoreceptor cell development P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0008623 chromatin accessibility complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046131 pyrimidine ribonucleoside metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004573 mannosyl-oligosaccharide glucosidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003817 complement factor D activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004084 branched-chain-amino-acid transaminase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0007100 centrosome separation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030742 GTP-dependent protein binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0017034 Rap guanyl-nucleotide exchange factor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006213 pyrimidine nucleoside metabolism P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0019914 cyclin-dependent protein kinase activating kinase\, intrinsic regulator activity F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0030306 ARF binding F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0003818 complement factor I activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004123 cystathionine gamma-lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0000797 condensin core heterodimer C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004336 galactosylceramidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006683 galactosylceramide catabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005237 inhibitory extracellular ligand-gated ion channel activity F 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0030731 guanidinoacetate N-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009434 flagellum (sensu Eukarya) C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030317 sperm motility P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0016724 oxidoreductase activity\, oxidizing metal ions\, oxygen as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0046513 ceramide biosynthesis P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0015068 glycine amidinotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046476 glycosylceramide biosynthesis P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0004322 ferroxidase activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0003934 GTP cyclohydrolase I activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0016929 SUMO-specific protease activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005679 nucleosome remodeling complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016722 oxidoreductase activity\, oxidizing metal ions F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0008274 gamma-tubulin ring complex C 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0004883 glucocorticoid receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006307 DNA dealkylation P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0008108 UDP-glucose-hexose-1-phosphate uridylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0001754 eye photoreceptor cell differentiation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0008392 arachidonic acid epoxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042393 histone binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006681 galactosylceramide metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004087 carbamoyl-phosphate synthase (ammonia) activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042132 fructose-bisphosphatase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0000114 G1-specific transcription in mitotic cell cycle P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0006330 single-stranded DNA binding P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006063 uronic acid metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0005847 mRNA cleavage and polyadenylation specificity factor complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008402 aromatase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004507 steroid 11-beta-monooxygenase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004877 complement component C3b receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003806 blood coagulation factor XII activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004334 fumarylacetoacetase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0050051 leukotriene-B4 20-monooxygenase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0008123 cholesterol 7-alpha-monooxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046521 sphingoid catabolism P 0 0 1 0 0 0 1 2 0 50 -0.477 0 0 0008487 prenyl-dependent CAAX protease activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046470 phosphatidylcholine metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0030617 TGFbeta receptor\, inhibitory cytoplasmic mediator activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0003804 blood coagulation factor X activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0019374 galactolipid metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0019912 cyclin-dependent protein kinase activating kinase activity F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0019585 glucuronate metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0045839 negative regulation of mitosis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030235 nitric-oxide synthase regulator activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005129 granulocyte macrophage colony-stimulating factor receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005157 macrophage colony stimulating factor receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046477 glycosylceramide catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004782 sulfinoalanine decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004508 steroid 17-alpha-monooxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030048 actin filament-based movement P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007525 somatic muscle development P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0030027 lamellipodium C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0019376 galactolipid catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0045010 actin nucleation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015056 corticotrophin-releasing factor receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004833 tryptophan 2\,3-dioxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046514 ceramide catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0007501 mesoderm cell fate specification P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008473 ornithine cyclodeaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0047341 fucose-1-phosphate guanylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008105 asymmetric protein localization P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0001507 acetylcholine breakdown in the synaptic cleft P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0019861 flagellum C 0 0 0 0 0 0 1 4 0 25 -0.477 0 0 0015067 amidinotransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0003933 GTP cyclohydrolase activity F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0030387 fructosamine-3-kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030393 fructoselysine metabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015484 hemolysin activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004717 focal adhesion kinase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004326 tetrahydrofolylpolyglutamate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008391 arachidonic acid monooxygenase activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0006004 fucose metabolism P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0005603 complement component C2 complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007587 sugar utilization P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003813 classical-complement-pathway C3/C5 convertase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006912 phagosome formation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004897 ciliary neurotrophic factor receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005412 glucose\:sodium symporter activity F 0 1 1 0 100 0 1 2 0 50 -0.477 0 0 0004133 glycogen debranching enzyme activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0017049 GTP-Rho binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016151 nickel ion binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0040001 mitotic spindle positioning and orientation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0018685 alkane 1-monooxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030348 syntaxin-3 binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0050577 GDP-L-fucose synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046398 UDP-glucuronate metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0008228 opsinization P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004498 calcidiol 1-monooxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008401 retinoic acid 4-hydroxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004961 thromboxane A2 receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004395 hexaprenyldihydroxybenzoate methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042602 flavin reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008001 fibrinogen F 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0005577 fibrinogen complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005973 fibrinogen beta chain C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0005974 fibrinogen gamma chain C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0016716 oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, another compound as one donor\, and incorporation of one atom of oxygen F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0017134 fibroblast growth factor binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007499 ectoderm/mesoderm interaction P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004086 carbamoyl-phosphate synthase activity F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0030424 axon C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008192 RNA guanylyltransferase activity F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0004254 acylaminoacyl-peptidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0017121 phospholipid scrambling P 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0004676 3-phosphoinositide-dependent protein kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006384 transcription initiation from Pol III promoter P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0045350 interferon-beta biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004284 acrosin activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003944 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005174 CD40 receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008478 pyridoxal kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003987 acetate-CoA ligase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0005810 endocytotic transport vesicle C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0030226 apolipoprotein receptor activity F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0009649 entrainment of circadian clock P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004447 iodide peroxidase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0016539 protein splicing P 0 1 5 0 20 0 1 5 0 20 -0.477 0 0 0005403 hydrogen\:sugar symporter-transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005053 peroxisome targeting signal-2 receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016558 peroxisome matrix protein import P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004958 prostaglandin F receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045814 negative regulation of gene expression\, epigenetic P 0 0 0 0 0 0 1 15 0 6.666667 -0.477 0 0 0046325 negative regulation of glucose import P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005849 mRNA cleavage factor complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042752 regulation of circadian rhythm P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004174 electron-transferring-flavoprotein dehydrogenase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0050353 trimethyllysine dioxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0048244 phytanoyl-CoA dioxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045652 regulation of megakaryocyte differentiation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0030219 megakaryocyte differentiation P 0 0 1 0 0 0 1 2 0 50 -0.477 0 0 0045765 regulation of angiogenesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0019807 aspartoacylase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0016834 other carbon-carbon lyase activity F 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0009226 nucleotide-sugar biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004657 proline dehydrogenase activity F 0 1 5 0 20 0 1 5 0 20 -0.477 0 0 0030363 pre-mRNA cleavage factor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0001735 prenylcysteine oxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030327 prenylated protein catabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030329 prenylcysteine metabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0019673 GDP-mannose metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0008480 sarcosine dehydrogenase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004188 lysosomal Pro-X carboxypeptidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0019211 phosphatase activator activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004658 propionyl-CoA carboxylase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0009843 thylakoid (sensu Glaucocystophyceae) C 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0004296 t-plasminogen activator activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009579 thylakoid C 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0000225 N-acetylglucosaminylphosphatidylinositol deacetylase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004085 butyryl-CoA dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007569 cell aging P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009536 plastid C 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0006358 regulation of global transcription from Pol II promoter P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004609 phosphatidylserine decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016458 gene silencing P 0 0 1 0 0 0 1 16 0 6.25 -0.477 0 0 0009842 cyanelle C 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0003990 acetylcholinesterase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0019215 intermediate filament binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005664 nuclear origin of replication recognition complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0000270 peptidoglycan metabolism P 0 0 0 0 0 0 1 9 0 11.11111 -0.477 0 0 0016525 negative regulation of angiogenesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045653 negative regulation of megakaryocyte differentiation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005118 sevenless binding F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004283 plasmin activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0016751 S-succinyltransferase activity F 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0035005 phosphatidylinositol-4-phosphate 3-kinase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004621 glycosylphosphatidylinositol phospholipase D activity F 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0005459 UDP-galactose transporter activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0016440 transcriptional gene silencing P 0 0 0 0 0 0 1 15 0 6.666667 -0.477 0 0 0006537 glutamate biosynthesis P 0 1 5 0 20 0 1 5 0 20 -0.477 0 0 0005018 platelet-derived growth factor\, alpha-receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045187 regulation of sleep P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030075 thylakoid (sensu Cyanobacteria) C 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0004614 phosphoglucomutase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004219 pyroglutamyl-peptidase I activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042734 presynaptic membrane C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045657 positive regulation of monocyte differentiation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042804 protein homooligomerization activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030263 apoptotic chromosome condensation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030076 light-harvesting complex C 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0004104 cholinesterase activity F 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0004959 prostaglandin I receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004430 1-phosphatidylinositol 4-kinase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0008327 methyl-CpG binding F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0006562 proline catabolism P 0 1 6 0 16.66667 0 1 6 0 16.66667 -0.477 0 0 0004505 phenylalanine 4-monooxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015961 diadenosine polyphosphate catabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030500 regulation of bone mineralization P 0 0 3 0 0 0 1 7 0 14.28571 -0.477 0 0 0046980 tapasin binding F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0042825 TAP complex C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004409 homoaconitate hydratase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0046967 cytosol to ER transport P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0009384 N-acylmannosamine kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004627 calcium-dependent cytosolic phospholipase A2 activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005041 low-density lipoprotein receptor activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0042222 interleukin-1 biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0016939 kinesin II complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0048004 antigen presentation\, endogenous peptide antigen P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0015919 peroxisomal membrane transport P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007405 neuroblast proliferation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004021 alanine transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004587 ornithine-oxo-acid transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006591 ornithine metabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0047568 3-oxo-5-beta-steroid 4-dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004984 olfactory receptor activity F 0 1 471 0 0.2123142 0 1 471 0 0.2123142 -0.477 0 0 0045357 regulation of interferon-beta biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0015742 alpha-ketoglutarate transport P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006797 polyphosphate metabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008907 integrase activity F 0 1 8 0 12.5 0 1 8 0 12.5 -0.477 0 0 0004628 calcium-independent cytosolic phospholipase A2 activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016417 S-acyltransferase activity F 0 0 0 0 0 0 1 6 0 16.66667 -0.477 0 0 0016748 succinyltransferase activity F 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0003717 Pol II transcription termination factor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006196 AMP catabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015909 long-chain fatty acid transport P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0016046 perception of fungi P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006054 N-acetylneuraminate metabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009620 response to fungi P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0042301 phosphate binding F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0015245 fatty acid transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006197 adenylate deaminase reaction P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045254 pyruvate dehydrogenase complex C 0 0 1 0 0 0 1 3 0 33.33333 -0.477 0 0 0004504 peptidylglycine monooxygenase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0045362 positive regulation of interleukin-1 biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045335 phagocytic vesicle C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0005519 cytoskeletal regulatory protein binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008111 alpha-methylacyl-CoA racemase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008761 UDP-N-acetylglucosamine 2-epimerase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030156 benzodiazepine receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005302 L-tyrosine transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008142 oxysterol binding F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0030297 transmembrane receptor protein tyrosine kinase activator activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0030502 negative regulation of bone mineralization P 0 1 6 0 16.66667 0 1 6 0 16.66667 -0.477 0 0 0008322 Pro-X carboxypeptidase activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004557 alpha-galactosidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003884 D-amino-acid oxidase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0005051 peroxisome targeting signal receptor activity F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0000268 peroxisome targeting sequence binding F 0 0 1 0 0 0 1 3 0 33.33333 -0.477 0 0 0005549 odorant binding F 0 1 2 0 50 0 1 3 0 33.33333 -0.477 0 0 0005395 eye pigment precursor transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015053 opsin F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046934 phosphatidylinositol-4\,5-bisphosphate 3-kinase activity F 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0006625 protein-peroxisome targeting P 0 0 1 0 0 0 1 2 0 50 -0.477 0 0 0030358 protein phosphatase type 2B\, intrinsic catalyst activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045329 carnitine biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0045029 UDP-activated nucleotide receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004324 ferredoxin-NADP reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045366 regulation of interleukin-13 biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0017128 phospholipid scramblase activity F 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0004990 oxytocin receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008534 purine-specific oxidized base lesion DNA N-glycosylase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0008458 carnitine O-octanoyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005770 late endosome C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0047115 trans-1\,2-dihydrobenzene-1\,2-diol dehydrogenase activity F 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0009353 oxoglutarate dehydrogenase complex (sensu Eukarya) C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004591 oxoglutarate dehydrogenase (lipoamide) activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004149 dihydrolipoamide S-succinyltransferase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0015065 uridine nucleotide receptor activity F 0 0 1 0 0 0 1 2 0 50 -0.477 0 0 0016529 sarcoplasmic reticulum C 0 1 5 0 20 0 1 5 0 20 -0.477 0 0 0008157 protein phosphatase 1 binding F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0030110 HLA-C specific inhibitory MHC class I receptor activity F 0 1 6 0 16.66667 0 1 6 0 16.66667 -0.477 0 0 0009882 blue light photoreceptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005742 mitochondrial outer membrane translocase complex C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0008106 alcohol dehydrogenase (NADP) activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016324 apical plasma membrane C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0016328 lateral plasma membrane C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004986 delta-opioid receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004987 kappa-opioid receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004988 mu-opioid receptor activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0015051 X-opioid receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0015039 NADPH-adrenodoxin reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005967 pyruvate dehydrogenase complex (sensu Eukarya) C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0005799 coatomer C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0008291 acetylcholine metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004503 monophenol monooxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009032 thymidine phosphorylase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0000305 response to oxygen radicals P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007506 gonadal mesoderm development P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0005677 chromatin silencing complex C 0 1 14 0 7.142857 0 1 14 0 7.142857 -0.477 0 0 0006342 chromatin silencing P 0 1 15 0 6.666667 0 1 15 0 6.666667 -0.477 0 0 0045621 positive regulation of lymphocyte differentiation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0050512 lactosylceramide 4-alpha-galactosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0019754 one-carbon compound catabolism P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0015030 Cajal body C 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0045622 regulation of T-helper cell differentiation P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0005032 tumor necrosis factor receptor cell differentiation\, type I F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045624 positive regulation of T-helper cell differentiation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0016647 oxidoreductase activity\, acting on the CH-NH group of donors\, oxygen as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0009445 putrescine metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0030019 tryptase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0030089 phycobilisome C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0001537 N-acetylgalactosamine 4-O-sulfotransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0045582 positive regulation of T-cell differentiation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0008118 N-acetyllactosaminide alpha-2\,3-sialyltransferase activity F 0 1 22 0 4.545455 0 1 22 0 4.545455 -0.477 0 0 0008599 protein phosphatase type 1\, intrinsic regulator activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015788 UDP-N-acetylglucosamine transport P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003913 DNA photolyase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0015780 nucleotide-sugar transport P 0 1 6 0 16.66667 0 1 7 0 14.28571 -0.477 0 0 0046978 TAP1 binding F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0047316 glutamine-phenylpyruvate transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004796 thromboxane-A synthase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0003979 UDP-glucose 6-dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004788 thiamin diphosphokinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045581 negative regulation of T-cell differentiation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004996 thyroid-stimulating hormone receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0006011 UDP-glucose metabolism P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0006065 UDP-glucuronate biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045623 negative regulation of T-helper cell differentiation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0006789 bilirubin conjugation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045064 T-helper 2 cell differentiation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0045628 regulation of T-helper 2 cell differentiation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0042787 protein ubiquitination during ubiquitin-dependent protein catabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008193 tRNA guanylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045625 regulation of T-helper 1 cell differentiation P 0 0 1 0 0 0 1 2 0 50 -0.477 0 0 0004312 fatty-acid synthase activity F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0007308 oocyte construction P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0005900 oncostatin-M receptor complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006991 response to sterol depletion P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0005993 trehalose catabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004997 thyrotropin-releasing hormone receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004371 glycerone kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006435 threonyl-tRNA aminoacylation P 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0004829 threonine-tRNA ligase activity F 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0004809 tRNA (guanine-N2-)-methyltransferase activity F 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0008410 CoA-transferase activity F 0 1 2 0 50 0 1 3 0 33.33333 -0.477 0 0 0005014 neurotrophin TRKA receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016783 sulfurtransferase activity F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0016592 Srb-mediator complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016503 pheromone receptor activity F 0 1 7 0 14.28571 0 1 7 0 14.28571 -0.477 0 0 0008292 acetylcholine biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015220 choline transporter activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0001517 N-acetylglucosamine 6-O-sulfotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0001526 proteoglycan sulfate transfer P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005696 telomere C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0030369 ICAM-3 receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046511 sphinganine biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0005019 platelet-derived growth factor\, beta-receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006668 sphinganine-1-phosphate metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0016489 immunoglobulin receptor activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0003860 3-hydroxyisobutyryl-CoA hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006667 sphinganine metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0009439 cyanate metabolism P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0006021 myo-inositol biosynthesis P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0004512 inositol-3-phosphate synthase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0017048 Rho binding F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0008176 tRNA (guanine-N7-)-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016922 ligand-dependent nuclear receptor interactor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006855 multidrug transport P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0030165 PDZ-domain binding F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0005016 neurotrophin TRKC receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005015 neurotrophin TRKB receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004811 tRNA isopentenyltransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0008745 N-acetylmuramoyl-L-alanine amidase activity F 0 1 6 0 16.66667 0 1 6 0 16.66667 -0.477 0 0 0009253 peptidoglycan catabolism P 0 1 8 0 12.5 0 1 8 0 12.5 -0.477 0 0 0046359 butyrate catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004938 alpha2-adrenergic receptor activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0015281 nonselective cation channel activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0019131 tripeptidyl-peptidase I activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007494 midgut development P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0003951 NAD kinase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0030677 ribonuclease P complex C 0 0 0 0 0 0 1 5 0 20 -0.477 0 0 0006339 positive regulation of transcription of homeotic gene (trithorax group) P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015432 bile acid porter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008554 sodium-exporting ATPase activity\, phosphorylative mechanism F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0048167 regulation of synaptic plasticity P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004925 prolactin receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005329 dopamine transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0048168 regulation of neuronal synaptic plasticity P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004422 hypoxanthine phosphoribosyltransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004679 SNF1A/AMP-activated protein kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008717 D-alanyl-D-alanine endopeptidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0017153 sodium\:dicarboxylate symporter activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0003808 protein C (activated) activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004186 carboxypeptidase C activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005333 norepinephrine transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0008275 gamma-tubulin small complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045063 T-helper 1 cell differentiation P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0030449 regulation of complement activation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0008559 xenobiotic-transporting ATPase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016872 intramolecular lyase activity F 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0016965 NAD synthase activity F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0005774 vacuolar membrane C 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0006587 serotonin biosynthesis from tryptophan P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004243 mitochondrial intermediate peptidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006627 mitochondrial processing P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0000808 origin of replication recognition complex C 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0009298 GDP-mannose biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030258 lipid modification P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0005402 cation\:sugar symporter activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0047616 acyl-CoA dehydrogenase (NADP) activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004603 phenylethanolamine N-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015196 L-tryptophan transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015216 purine nucleotide transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004733 pyridoxamine-phosphate oxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015910 peroxisomal long-chain fatty acid import P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006685 sphingomyelin catabolism P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004510 tryptophan 5-monooxygenase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0019237 centromeric DNA binding F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004631 phosphomevalonate kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0001519 peptide amidation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015194 L-serine transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016323 basolateral plasma membrane C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005782 peroxisomal matrix C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008488 gamma-glutamyl carboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0001612 A2B adenosine receptor activity\, G-protein coupled F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0001611 A2A adenosine receptor activity\, G-protein coupled F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0006906 nonselective vesicle fusion P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004339 glucan 1\,4-alpha-glucosidase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004294 tripeptidyl-peptidase II activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007170 transmembrane receptor protein tyrosine kinase ligand binding P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0004736 pyruvate carboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008434 vitamin D3 receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003883 CTP synthase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0030227 apolipoprotein E receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004297 u-plasminogen activator activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006858 extracellular transport P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030377 U-plasminogen activator receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0019783 ubiquitin-like-specific protease activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0008640 ubiquitin-like conjugating enzyme activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046979 TAP2 binding F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0008160 protein tyrosine phosphatase activator activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008539 proteasome inhibitor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016471 hydrogen-translocating V-type ATPase complex C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0006659 phosphatidylserine biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0008187 poly-pyrimidine tract binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005368 taurine transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0008778 acyl-CoA thioesterase II activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005308 creatine transporter activity F 0 0 1 0 0 0 1 2 0 50 -0.477 0 0 0015633 zinc porter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0017159 pantetheinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016520 growth hormone-releasing hormone receptor activity F 0 1 7 0 14.28571 0 1 7 0 14.28571 -0.477 0 0 0005499 vitamin D binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003952 NAD synthase (glutamine-hydrolyzing) activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0005286 basic amino acid permease activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015187 glycine transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004534 5’-3’ exoribonuclease activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008451 Xaa-Pro aminopeptidase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0004854 xanthine dehydrogenase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004855 xanthine oxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006143 purine metabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005462 UDP-N-acetylglucosamine transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005294 neutral L-amino acid porter activity F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0008409 5’-3’ exonuclease activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0009437 carnitine metabolism P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0016322 neuronal remodeling P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004098 cerebroside-sulfatase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003776 muscle motor activity F 0 1 6 0 16.66667 0 1 6 0 16.66667 -0.477 0 0 0000146 microfilament motor activity F 0 0 1 0 0 0 1 7 0 14.28571 -0.477 0 0 0015791 polyol transport P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0030586 [methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing) activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009158 ribonucleoside monophosphate catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0007135 meiosis II P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0009125 nucleoside monophosphate catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0009169 purine ribonucleoside monophosphate catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0009128 purine nucleoside monophosphate catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0017151 DEAD/H-box RNA helicase binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005432 calcium\:sodium antiporter activity F 0 1 5 0 20 0 1 5 0 20 -0.477 0 0 0005736 DNA-directed RNA polymerase I complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046033 AMP metabolism P 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0042428 serotonin metabolism P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0003948 N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004066 asparagine synthase (glutamine-hydrolyzing) activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0030326 limb morphogenesis P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0006529 asparagine biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007136 meiotic prophase II P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004980 melanocyte stimulating hormone receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0045092 interleukin-18 receptor complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0000726 non-recombinational repair P 0 0 0 0 0 0 1 5 0 20 -0.477 0 0 0003900 DNA-directed RNA polymerase I activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006369 transcription termination from Pol II promoter P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015253 sugar/polyol channel activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0008459 chondroitin 6-sulfotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008428 ribonuclease inhibitor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007026 microtubule stabilization P 0 1 9 0 11.11111 0 1 9 0 11.11111 -0.477 0 0 0004060 arylamine N-acetyltransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0008648 tachykinin F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004286 proprotein convertase 2 activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0017061 5’-methylthioadenosine phosphorylase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046219 indolalkylamine biosynthesis P 0 0 0 0 0 0 1 4 0 25 -0.477 0 0 0003875 ADP-ribosylarginine hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016034 maleylacetoacetate isomerase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016528 sarcoplasm C 0 0 0 0 0 0 1 5 0 20 -0.477 0 0 0004285 proprotein convertase 1 activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0000186 activation of MAPKK P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0000094 septin assembly and septum formation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0001573 ganglioside metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0006689 ganglioside catabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006895 Golgi to endosome transport P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0040008 regulation of growth P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0046479 glycosphingolipid catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0047865 dimethylglycine dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045610 regulation of hemocyte differentiation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016056 rhodopsin mediated signaling P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0006990 unfolded protein response\, target gene transcriptional activation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006907 pinocytosis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008456 alpha-N-acetylgalactosaminidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004567 beta-mannosidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007423 sensory organ development P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006051 N-acetylmannosamine metabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016858 racemase and epimerase activity\, acting on other compounds F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0045127 N-acetylglucosamine kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006266 DNA ligation P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0007497 posterior midgut development P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005061 aryl hydrocarbon receptor nuclear translocator activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004056 argininosuccinate lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015052 beta3-adrenergic receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006050 mannosamine metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0045211 postsynaptic membrane C 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0045071 negative regulation of viral genome replication P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007184 SMAD protein nuclear translocation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007180 TGFbeta ligand binding to type II receptor P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004316 3-oxoacyl-[acyl-carrier protein] reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042386 hemocyte differentiation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0042084 5-methyltetrahydrofolate-dependent methyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0048015 phosphoinositide-mediated signaling P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0047438 2-dehydro-3-deoxy-L-pentonate aldolase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016704 oxidoreductase activity\, acting on single donors with incorporation of molecular oxygen\, miscellaneous F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004145 diamine N-acetyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0018987 osmoregulation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0017074 procollagen N-endopeptidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030271 chymase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0007617 mating behavior P 0 1 1 0 100 0 1 3 0 33.33333 -0.477 0 0 0005026 type II transforming growth factor-beta receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0005889 hydrogen/potassium-exchanging ATPase complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030354 melanin-concentrating hormone activity F 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0019911 structural constituent of myelin sheath F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016910 SAP kinase 3 activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0050121 N-acylglucosamine 2-epimerase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0003908 methylated-DNA-[protein]-cysteine S-methyltransferase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0006992 sterol depletion response\, sterol regulatory element binding-protein cleavage P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0001527 microfibril C 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0016921 pyroglutamyl-peptidase II activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004156 dihydropteroate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004838 tyrosine transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030318 melanocyte differentiation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009191 ribonucleoside diphosphate catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0019310 myo-inositol catabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0019862 IgA binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009992 cellular osmoregulation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008705 methionine synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008796 bis(5’-nucleosyl)-tetraphosphatase activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0016234 inclusion body C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0048016 inositol phosphate-mediated signaling P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004792 thiosulfate sulfurtransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0007206 metabotropic glutamate receptor\, phospholipase C activating pathway P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0007171 transmembrane receptor protein tyrosine kinase activation (dimerization) P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006883 sodium ion homeostasis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015694 mercury ion transport P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004941 beta2-adrenergic receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015320 phosphate carrier activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004240 mitochondrial processing peptidase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0015097 mercury ion transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008900 hydrogen/potassium-exchanging ATPase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0008268 receptor signaling protein tyrosine kinase signaling protein activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0015727 lactate transport P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045913 positive regulation of carbohydrate metabolism P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0030228 lipoprotein receptor activity F 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0001523 retinoid metabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0047878 erythritol kinase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0005655 nucleolar ribonuclease P complex C 0 1 5 0 20 0 1 5 0 20 -0.477 0 0 0046965 retinoid X receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006303 double-strand break repair via nonhomologous end-joining P 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0004491 methylmalonate-semialdehyde dehydrogenase (acylating) activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016784 3-mercaptopyruvate sulfurtransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004228 gelatinase A activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004248 stromelysin 1 activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008130 neutrophil collagenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004229 gelatinase B activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030303 stromelysin 2 activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009440 cyanate catabolism P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0006573 valine metabolism P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0015129 lactate transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006111 regulation of gluconeogenesis P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0019098 reproductive behavior P 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0006109 regulation of carbohydrate metabolism P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0005477 pyruvate carrier activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006848 pyruvate transport P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006610 ribosomal protein-nucleus import P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004055 argininosuccinate synthase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0030273 melanin-concentrating hormone receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0000093 mitotic telophase P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0000016 lactase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045368 positive regulation of interleukin-13 biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042824 MHC class I peptide loading complex C 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0008195 phosphatidate phosphatase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0015956 bis(5’-nucleosidyl) oligophosphate metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0018184 protein amino acid polyamination P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008521 acetyl-CoA transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0001707 mesoderm formation P 0 0 0 0 0 0 1 4 0 25 -0.477 0 0 0047696 beta-adrenergic-receptor kinase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0045655 regulation of monocyte differentiation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0007369 gastrulation P 0 0 2 0 0 0 1 6 0 16.66667 -0.477 0 0 0005796 Golgi lumen C 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0047961 glycine N-acyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015959 diadenosine polyphosphate metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0015520 tetracycline\:hydrogen antiporter activity F 0 1 9 0 11.11111 0 1 9 0 11.11111 -0.477 0 0 0030192 Hsp70/Hsc70 protein regulator activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0050528 acyloxyacyl hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004052 arachidonate 12-lipoxygenase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0008753 NADPH dehydrogenase (quinone) activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042447 hormone catabolism P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0016919 nardilysin activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0007468 regulation of rhodopsin gene activity P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016979 lipoate-protein ligase activity F 0 0 0 0 0 0 1 4 0 25 -0.477 0 0 0046696 lipopolysaccharide receptor complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016603 glutaminyl-peptide cyclotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0001704 formation of primary germ layer P 0 0 0 0 0 0 1 4 0 25 -0.477 0 0 0008937 ferredoxin reductase activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004051 arachidonate 5-lipoxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016492 neurotensin receptor activity\, G-protein coupled F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0048002 antigen presentation\, peptide antigen P 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0015254 glycerol channel activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045360 regulation of interleukin-1 biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0016731 oxidoreductase activity\, acting on reduced ferredoxin as donor\, NAD or NADP as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0008413 8-oxo-7\,8-dihydroguanine triphosphatase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0019794 nonprotein amino acid metabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0030259 lipid glycosylation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006370 mRNA capping P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0004482 mRNA (guanine-N7-)-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0006710 androgen catabolism P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030304 trypsin inhibitor activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0015904 tetracycline transport P 0 1 9 0 11.11111 0 1 9 0 11.11111 -0.477 0 0 0000177 cytoplasmic exosome (RNase complex) C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016316 phosphatidylinositol-3\,4-bisphosphate 4-phosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005915 zonula adherens C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016414 O-octanoyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004230 glutamyl aminopeptidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0000176 nuclear exosome (RNase complex) C 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.477 0 0 0003791 membrane associated actin binding F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0030601 aminopeptidase B activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016415 octanoyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004502 kynurenine 3-monooxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016649 oxidoreductase activity\, acting on the CH-NH group of donors\, quinone or similar compound as acceptor F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0045639 positive regulation of myeloid blood cell differentiation P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004923 leukemia inhibitory factor receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004882 androgen receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0007402 ganglion mother cell fate determination P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005038 death receptor interacting protein activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004771 sterol esterase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0006152 purine nucleoside catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0045576 mast cell activation P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042454 ribonucleoside catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0046130 purine ribonucleoside catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0015958 bis(5’-nucleosidyl) oligophosphate catabolism P 0 0 0 0 0 0 1 1 0 100 -0.477 0 0 0004561 alpha-N-acetylglucosaminidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005146 leukemia inhibitory factor receptor binding F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0000125 PCAF complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008613 diuretic hormone activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009164 nucleoside catabolism P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0030311 poly-N-acetyllactosamine biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016730 oxidoreductase activity\, acting on iron-sulfur proteins as donors F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0004964 lutropin-choriogonadotropic hormone receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0015925 galactosidase activity F 0 0 0 0 0 0 1 7 0 14.28571 -0.477 0 0 0008273 calcium\, potassium\:sodium antiporter activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030139 endocytic vesicle C 0 0 1 0 0 0 1 5 0 20 -0.477 0 0 0004571 mannosyl-oligosaccharide 1\,2-alpha-mannosidase activity F 0 1 11 0 9.090909 0 1 11 0 9.090909 -0.477 0 0 0008269 JAK pathway signal transduction adaptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008493 tetracycline transporter activity F 0 0 0 0 0 0 1 9 0 11.11111 -0.477 0 0 0008803 bis(5’-nucleosyl)-tetraphosphatase (symmetrical) activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008532 N-acetyllactosaminide beta-1\,3-N-acetylglucosaminyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0042427 serotonin biosynthesis P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0004558 alpha-glucosidase activity F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0005731 nucleolus organizer complex C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0045359 positive regulation of interferon-beta biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005688 snRNP U6 C 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008798 beta-aspartyl-peptidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0030296 protein tyrosine kinase activator activity F 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0042895 antibiotic transporter activity F 0 0 0 0 0 0 1 9 0 11.11111 -0.477 0 0 0008112 nicotinamide N-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0008013 beta-catenin binding F 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0015465 lysin activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0047915 ganglioside galactosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0016080 synaptic vesicle targeting P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0015793 glycerol transport P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004081 bis(5’-nucleosyl)-tetraphosphatase (asymmetrical) activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0046326 positive regulation of glucose import P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0045722 positive regulation of gluconeogenesis P 0 1 2 0 50 0 1 2 0 50 -0.477 0 0 0009642 response to light intensity P 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0004995 tachykinin receptor activity F 0 1 4 0 25 0 1 4 0 25 -0.477 0 0 0009452 RNA capping P 0 0 0 0 0 0 1 2 0 50 -0.477 0 0 0017042 glycosylceramidase activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0005025 type I transforming growth factor-beta receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.477 0 0 0009586 rhodopsin mediated phototransduction P 0 0 0 0 0 0 1 3 0 33.33333 -0.477 0 0 0005496 steroid binding F 3 16 29 18.75 55.17241 4 27 49 14.81481 55.10204 -0.501 0 0 0006112 energy reserve metabolism P 0 4 6 0 66.66666 4 27 33 14.81481 81.81818 -0.501 0 0 0006304 DNA modification P 1 4 4 25 100 3 21 41 14.28571 51.21951 -0.504 0 0 0030484 muscle fiber C 0 0 1 0 0 3 21 45 14.28571 46.66667 -0.504 0 0 0004620 phospholipase activity F 0 2 4 0 50 5 33 76 15.15152 43.42105 -0.504 0 0 0030054 cell junction C 0 0 1 0 0 7 45 97 15.55556 46.39175 -0.519 0 0 0030017 sarcomere C 0 0 3 0 0 2 15 30 13.33333 50 -0.521 0 0 0015297 antiporter activity F 1 7 19 14.28571 36.84211 2 15 65 13.33333 23.07692 -0.521 0 0 0007507 heart development P 2 15 20 13.33333 75 2 15 20 13.33333 75 -0.521 0 0 0019210 kinase inhibitor activity F 0 2 2 0 100 2 15 24 13.33333 62.5 -0.521 0 0 0030016 myofibril C 0 0 0 0 0 2 15 30 13.33333 50 -0.521 0 0 0006898 receptor mediated endocytosis P 2 15 21 13.33333 71.42857 2 15 21 13.33333 71.42857 -0.521 0 0 0046148 pigment biosynthesis P 0 0 0 0 0 2 15 22 13.33333 68.18182 -0.521 0 0 0006401 RNA catabolism P 1 9 13 11.11111 69.23077 2 15 22 13.33333 68.18182 -0.521 0 0 0016311 dephosphorylation P 1 1 1 100 100 13 80 169 16.25 47.33728 -0.533 0 0 0006486 protein amino acid glycosylation P 8 39 72 20.51282 54.16667 11 69 119 15.94203 57.98319 -0.561 0 0 0015085 calcium ion transporter activity F 0 2 2 0 100 1 9 12 11.11111 75 -0.575 0 0 0016460 myosin II C 0 0 0 0 0 1 9 25 11.11111 36 -0.575 0 0 0006559 phenylalanine catabolism P 1 9 10 11.11111 90 1 9 10 11.11111 90 -0.575 0 0 0005518 collagen binding F 1 9 13 11.11111 69.23077 1 9 13 11.11111 69.23077 -0.575 0 0 0004143 diacylglycerol kinase activity F 1 9 19 11.11111 47.36842 1 9 19 11.11111 47.36842 -0.575 0 0 0004629 phospholipase C activity F 1 2 4 50 50 1 9 29 11.11111 31.03448 -0.575 0 0 0019208 phosphatase regulator activity F 0 1 1 0 100 1 9 17 11.11111 52.94118 -0.575 0 0 0030182 neuron differentiation P 0 4 8 0 50 1 9 13 11.11111 69.23077 -0.575 0 0 0007530 sex determination P 1 7 11 14.28571 63.63636 1 9 13 11.11111 69.23077 -0.575 0 0 0015875 vitamin/cofactor transport P 0 1 1 0 100 1 9 13 11.11111 69.23077 -0.575 0 0 0006691 leukotriene metabolism P 0 1 3 0 33.33333 1 9 14 11.11111 64.28571 -0.575 0 0 0005921 gap junction C 1 2 5 50 40 1 9 27 11.11111 33.33333 -0.575 0 0 0008584 male gonad development P 1 9 12 11.11111 75 1 9 12 11.11111 75 -0.575 0 0 0006575 amino acid derivative metabolism P 0 1 1 0 100 4 28 45 14.28571 62.22222 -0.582 0 0 0000902 cellular morphogenesis P 0 1 4 0 25 4 28 38 14.28571 73.68421 -0.582 0 0 0005604 basement membrane C 3 15 20 20 75 4 28 45 14.28571 62.22222 -0.582 0 0 0006725 aromatic compound metabolism P 0 11 22 0 50 8 52 91 15.38461 57.14286 -0.59 0 0 0006464 protein modification P 14 47 88 29.78723 53.40909 105 595 1294 17.64706 45.98145 -0.594 0 0 0009064 glutamine family amino acid metabolism P 0 0 0 0 0 3 22 46 13.63636 47.82609 -0.594 0 0 0040029 regulation of gene expression\, epigenetic P 0 0 0 0 0 3 22 58 13.63636 37.93103 -0.594 0 0 0006487 N-linked glycosylation P 2 16 28 12.5 57.14286 3 22 35 13.63636 62.85714 -0.594 0 0 0016810 hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds F 1 8 13 12.5 61.53846 9 58 106 15.51724 54.71698 -0.597 0 0 0008234 cysteine-type peptidase activity F 1 15 21 6.666667 71.42857 11 70 162 15.71429 43.20988 -0.614 0 0 0008374 O-acyltransferase activity F 0 0 0 0 0 2 16 19 12.5 84.21053 -0.623 0 0 0007585 respiratory gaseous exchange P 2 16 21 12.5 76.19048 2 16 21 12.5 76.19048 -0.623 0 0 0016706 oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, 2-oxoglutarate as one donor\, and incorporation of one atom each of oxygen into both donors F 1 8 11 12.5 72.72727 2 16 22 12.5 72.72727 -0.623 0 0 0016410 N-acyltransferase activity F 0 0 0 0 0 2 16 27 12.5 59.25926 -0.623 0 0 0007259 JAK-STAT cascade P 2 14 17 14.28571 82.35294 2 16 20 12.5 80 -0.623 0 0 0016814 hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds\, in cyclic amidines F 0 0 0 0 0 2 16 30 12.5 53.33333 -0.623 0 0 0008406 gonad development P 1 2 3 50 66.66666 2 16 21 12.5 76.19048 -0.623 0 0 0007189 G-protein signaling\, adenylate cyclase activating pathway P 1 2 2 50 100 2 16 21 12.5 76.19048 -0.623 0 0 0008371 obsolete biological process P 0 0 0 0 0 37 219 314 16.89498 69.74522 -0.641 0 0 0015698 inorganic anion transport P 0 0 0 0 0 6 41 78 14.63415 52.5641 -0.647 0 0 0007160 cell-matrix adhesion P 6 41 83 14.63415 49.39759 6 41 84 14.63415 48.80952 -0.647 0 0 0007169 transmembrane receptor protein tyrosine kinase signaling pathway P 5 36 63 13.88889 57.14286 9 59 97 15.25424 60.82474 -0.654 0 0 0006916 anti-apoptosis P 8 53 72 15.09434 73.61111 9 59 80 15.25424 73.75 -0.654 0 0 0016790 thiolester hydrolase activity F 0 0 0 0 0 4 29 85 13.7931 34.11765 -0.661 0 0 0016758 transferase activity\, transferring hexosyl groups F 1 9 29 11.11111 31.03448 12 77 152 15.58442 50.65789 -0.674 0 0 0030121 AP-1 adaptor complex C 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0045859 regulation of protein kinase activity P 0 0 0 0 0 0 2 5 0 40 -0.675 0 0 0016312 inositol bisphosphate phosphatase activity F 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0000795 synaptonemal complex C 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0001719 inhibition of caspase activation P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0042403 thyroid hormone metabolism P 0 0 0 0 0 0 2 7 0 28.57143 -0.675 0 0 0005123 death receptor binding F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0008099 synaptic vesicle endocytosis P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0008240 tripeptidyl-peptidase activity F 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0007281 germ-cell development P 0 2 7 0 28.57143 0 2 7 0 28.57143 -0.675 0 0 0006702 androgen biosynthesis P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0008634 negative regulation of survival gene products P 0 2 7 0 28.57143 0 2 7 0 28.57143 -0.675 0 0 0001710 mesoderm cell fate commitment P 0 0 0 0 0 0 2 4 0 50 -0.675 0 0 0003953 NAD nucleosidase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0016745 transketolase and transaldolase activity F 0 0 0 0 0 0 2 4 0 50 -0.675 0 0 0004946 bombesin receptor activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0019976 interleukin-2 binding F 0 0 0 0 0 0 2 3 0 66.66666 -0.675 0 0 0016824 hydrolase activity\, acting on acid halide bonds F 0 0 0 0 0 0 2 5 0 40 -0.675 0 0 0004947 bradykinin receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0005804 secretory vesicle membrane C 0 2 5 0 40 0 2 5 0 40 -0.675 0 0 0007485 male genital morphogenesis (sensu Holometabola) P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0005913 cell-cell adherens junction C 0 1 2 0 50 0 2 4 0 50 -0.675 0 0 0016403 dimethylargininase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0006768 biotin metabolism P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0017114 wide-spectrum protease inhibitor activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0008494 translation activator activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0016248 channel inhibitor activity F 0 0 0 0 0 0 2 6 0 33.33333 -0.675 0 0 0030312 external encapsulating structure C 0 0 0 0 0 0 2 4 0 50 -0.675 0 0 0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity F 0 2 5 0 40 0 2 5 0 40 -0.675 0 0 0003845 11-beta-hydroxysteroid dehydrogenase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004090 carbonyl reductase (NADPH) activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0008109 N-acetyllactosaminide beta-1\,6-N-acetylglucosaminyltransferase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0019120 hydrolase activity\, acting on acid halide bonds\, in C-halide compounds F 0 0 0 0 0 0 2 5 0 40 -0.675 0 0 0006013 mannose metabolism P 0 0 1 0 0 0 2 3 0 66.66666 -0.675 0 0 0016933 glycine-gated ion channel activity F 0 0 0 0 0 0 2 4 0 50 -0.675 0 0 0015893 drug transport P 0 0 0 0 0 0 2 12 0 16.66667 -0.675 0 0 0000002 mitochondrial genome maintenance P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0008332 low voltage-gated calcium channel activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0042402 biogenic amine catabolism P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0005017 platelet-derived growth factor receptor activity F 0 0 1 0 0 0 2 3 0 66.66666 -0.675 0 0 0016920 pyroglutamyl-peptidase activity F 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0046218 indolalkylamine catabolism P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0016714 oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, reduced pteridine as one donor\, and incorporation of one atom of oxygen F 0 0 0 0 0 0 2 4 0 50 -0.675 0 0 0015918 sterol transport P 0 0 0 0 0 0 2 3 0 66.66666 -0.675 0 0 0006914 autophagy P 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0005451 monovalent cation\:proton antiporter activity F 0 0 0 0 0 0 2 10 0 20 -0.675 0 0 0046473 phosphatidic acid metabolism P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0005427 proton-dependent oligopeptide transporter activity F 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0005372 water transporter activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004184 lysine carboxypeptidase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0030330 DNA damage response\, signal transduction by p53 class mediator P 0 0 0 0 0 0 2 4 0 50 -0.675 0 0 0042436 indole derivative catabolism P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0007603 phototransduction\, visible light P 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0046030 inositol trisphosphate phosphatase activity F 0 0 0 0 0 0 2 7 0 28.57143 -0.675 0 0 0016997 alpha-sialidase activity F 0 0 0 0 0 0 2 5 0 40 -0.675 0 0 0016808 proprotein convertase activity F 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0008253 5’-nucleotidase activity F 0 2 5 0 40 0 2 5 0 40 -0.675 0 0 0019787 ubiquitin-like-protein ligase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0003994 aconitate hydratase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0008175 tRNA methyltransferase activity F 0 0 1 0 0 0 2 7 0 28.57143 -0.675 0 0 0009648 response to photoperiod P 0 1 1 0 100 0 2 2 0 100 -0.675 0 0 0042461 photoreceptor cell development P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0045075 regulation of interleukin-12 biosynthesis P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0004738 pyruvate dehydrogenase activity F 0 0 0 0 0 0 2 3 0 66.66666 -0.675 0 0 0030250 guanylate cyclase activator activity F 0 0 1 0 0 0 2 6 0 33.33333 -0.675 0 0 0030249 guanylate cyclase regulator activity F 0 0 0 0 0 0 2 6 0 33.33333 -0.675 0 0 0006518 peptide metabolism P 0 1 3 0 33.33333 0 2 4 0 50 -0.675 0 0 0030278 regulation of bone formation P 0 0 0 0 0 0 2 7 0 28.57143 -0.675 0 0 0035036 sperm-egg recognition P 0 0 0 0 0 0 2 4 0 50 -0.675 0 0 0000904 cellular morphogenesis during differentiation P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0005816 spindle pole body C 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0046850 regulation of bone remodeling P 0 0 0 0 0 0 2 8 0 25 -0.675 0 0 0007455 eye-antennal disc metamorphosis P 0 0 0 0 0 0 2 4 0 50 -0.675 0 0 0042090 interleukin-12 biosynthesis P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0016045 perception of bacteria P 0 0 0 0 0 0 2 3 0 66.66666 -0.675 0 0 0046006 regulation of activated T-cell proliferation P 0 0 0 0 0 0 2 3 0 66.66666 -0.675 0 0 0042226 interleukin-6 biosynthesis P 0 0 0 0 0 0 2 3 0 66.66666 -0.675 0 0 0019834 phospholipase A2 inhibitor activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0015012 heparan sulfate proteoglycan biosynthesis P 0 0 2 0 0 0 2 4 0 50 -0.675 0 0 0030201 heparan sulfate proteoglycan metabolism P 0 0 0 0 0 0 2 4 0 50 -0.675 0 0 0001745 compound eye morphogenesis (sensu Drosophila) P 0 0 0 0 0 0 2 4 0 50 -0.675 0 0 0019344 cysteine biosynthesis P 0 1 1 0 100 0 2 2 0 100 -0.675 0 0 0030166 proteoglycan biosynthesis P 0 0 0 0 0 0 2 5 0 40 -0.675 0 0 0045580 regulation of T-cell differentiation P 0 1 1 0 100 0 2 3 0 66.66666 -0.675 0 0 0015165 pyrimidine nucleotide sugar transporter activity F 0 0 0 0 0 0 2 5 0 40 -0.675 0 0 0018108 peptidyl-tyrosine phosphorylation P 0 0 0 0 0 0 2 3 0 66.66666 -0.675 0 0 0046530 photoreceptor cell differentiation P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0045408 regulation of interleukin-6 biosynthesis P 0 0 0 0 0 0 2 3 0 66.66666 -0.675 0 0 0019674 nicotinamide adenine dinucleotide metabolism P 0 0 0 0 0 0 2 3 0 66.66666 -0.675 0 0 0017057 6-phosphogluconolactonase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0006020 myo-inositol metabolism P 0 0 0 0 0 0 2 4 0 50 -0.675 0 0 0003762 histone-specific chaperone activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0008943 glyceraldehyde-3-phosphate dehydrogenase activity F 0 0 0 0 0 0 2 4 0 50 -0.675 0 0 0004008 copper-exporting ATPase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0007158 neuronal cell adhesion P 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0030316 osteoclast differentiation P 0 0 1 0 0 0 2 4 0 50 -0.675 0 0 0015811 L-cystine transport P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0016857 racemase and epimerase activity\, acting on carbohydrates and derivatives F 0 0 1 0 0 0 2 5 0 40 -0.675 0 0 0005587 collagen type IV C 0 2 7 0 28.57143 0 2 7 0 28.57143 -0.675 0 0 0007043 intercellular junction assembly P 0 2 5 0 40 0 2 5 0 40 -0.675 0 0 0008147 structural constituent of bone F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0045649 regulation of macrophage differentiation P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0000930 gamma-tubulin complex C 0 0 0 0 0 0 2 5 0 40 -0.675 0 0 0004944 C5a anaphylatoxin receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004384 membrane-associated guanylate kinase F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0004914 interleukin-5 receptor activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0016744 transferase activity\, transferring aldehyde or ketonic groups F 0 0 0 0 0 0 2 4 0 50 -0.675 0 0 0007191 dopamine receptor\, adenylate cyclase activating pathway P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0008396 oxysterol 7-alpha-hydroxylase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0006540 glutamate decarboxylation to succinate P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004351 glutamate decarboxylase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0015199 betaine transporter activity F 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0045351 interferon type I biosynthesis P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0005602 complement component C1q complex C 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0019967 interleukin-1\, Type I\, activating binding F 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0016823 hydrolase activity\, acting on acid carbon-carbon bonds\, in ketonic substances F 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0016822 hydrolase activity\, acting on acid carbon-carbon bonds F 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0045577 regulation of B-cell differentiation P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0007210 serotonin receptor signaling pathway P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0007197 muscarinic acetyl choline receptor\, adenylate cyclase inhibiting pathway P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0019363 pyridine nucleotide biosynthesis P 0 0 1 0 0 0 2 5 0 40 -0.675 0 0 0000394 RNA splicing\, via endonucleolytic cleavage and ligation P 0 0 0 0 0 0 2 5 0 40 -0.675 0 0 0042924 neuromedin U binding F 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0045670 regulation of osteoclast differentiation P 0 0 1 0 0 0 2 3 0 66.66666 -0.675 0 0 0006600 creatine metabolism P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0005513 calcium ion sensing P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0006744 ubiquinone biosynthesis P 0 2 5 0 40 0 2 5 0 40 -0.675 0 0 0003706 ligand-regulated transcription factor activity F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0042396 phosphagen biosynthesis P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0006599 phosphagen metabolism P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0005232 serotonin-activated cation-selective channel activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0042325 regulation of phosphorylation P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0015368 calcium\:cation antiporter activity F 0 0 0 0 0 0 2 6 0 33.33333 -0.675 0 0 0006335 DNA replication dependent nucleosome assembly P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004246 peptidyl-dipeptidase A activity F 0 2 7 0 28.57143 0 2 7 0 28.57143 -0.675 0 0 0003943 N-acetylgalactosamine-4-sulfatase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004466 long-chain-acyl-CoA dehydrogenase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0003997 acyl-CoA oxidase activity F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0046851 negative regulation of bone remodeling P 0 0 0 0 0 0 2 5 0 40 -0.675 0 0 0016423 tRNA (guanine) methyltransferase activity F 0 0 0 0 0 0 2 5 0 40 -0.675 0 0 0019220 regulation of phosphate metabolism P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0042723 thiamin and derivative metabolism P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0045936 negative regulation of phosphate metabolism P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0019605 butyrate metabolism P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0006381 mRNA editing P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0019968 interleukin-1\, Type II\, blocking binding F 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0008393 fatty acid (omega-1)-hydroxylase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0006677 glycosylceramide metabolism P 0 0 0 0 0 0 2 3 0 66.66666 -0.675 0 0 0015114 phosphate transporter activity F 0 1 1 0 100 0 2 2 0 100 -0.675 0 0 0015173 aromatic amino acid transporter activity F 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0015908 fatty acid transport P 0 1 1 0 100 0 2 2 0 100 -0.675 0 0 0005087 Ran guanyl-nucleotide exchange factor activity F 0 2 5 0 40 0 2 5 0 40 -0.675 0 0 0007150 growth pattern P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0042605 peptide antigen binding F 0 2 12 0 16.66667 0 2 12 0 16.66667 -0.675 0 0 0015433 peptide antigen transporter activity F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0006002 fructose 6-phosphate metabolism P 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0015215 nucleotide transporter activity F 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0030041 actin filament polymerization P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0016547 RNA editing P 0 0 1 0 0 0 2 3 0 66.66666 -0.675 0 0 0046520 sphingoid biosynthesis P 0 0 0 0 0 0 2 3 0 66.66666 -0.675 0 0 0004939 beta-adrenergic receptor activity F 0 0 0 0 0 0 2 3 0 66.66666 -0.675 0 0 0017068 glutamyl-tRNA(Gln) amidotransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004335 galactokinase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0009448 aminobutyrate metabolism P 0 1 1 0 100 0 2 2 0 100 -0.675 0 0 0045252 oxoglutarate dehydrogenase complex C 0 1 3 0 33.33333 0 2 4 0 50 -0.675 0 0 0004739 pyruvate dehydrogenase (lipoamide) activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0016499 orexin receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0006658 phosphatidylserine metabolism P 0 1 1 0 100 0 2 3 0 66.66666 -0.675 0 0 0008241 peptidyl-dipeptidase activity F 0 0 0 0 0 0 2 6 0 33.33333 -0.675 0 0 0004615 phosphomannomutase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0008048 calcium sensitive guanylate cyclase activator activity F 0 2 5 0 40 0 2 5 0 40 -0.675 0 0 0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity F 0 2 7 0 28.57143 0 2 7 0 28.57143 -0.675 0 0 0006684 sphingomyelin metabolism P 0 1 6 0 16.66667 0 2 8 0 25 -0.675 0 0 0004767 sphingomyelin phosphodiesterase activity F 0 2 5 0 40 0 2 5 0 40 -0.675 0 0 0046658 extrinsic to plasma membrane\, GPI-anchored C 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0045597 positive regulation of cell differentiation P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0005485 v-SNARE activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0045069 regulation of viral genome replication P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0016934 glycine-gated chloride channel activity F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0004624 secreted phospholipase A2 activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0009331 glycerol-3-phosphate dehydrogenase complex C 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0015015 heparan sulfate proteoglycan biosynthesis\, enzymatic modification P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0003827 alpha-1\,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0006977 DNA damage response\, signal transduction by p53 class mediator resulting in cell cycle arrest P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0008466 glycogenin glucosyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004359 glutaminase activity F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0016556 mRNA modification P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0005068 transmembrane receptor protein tyrosine kinase adaptor protein activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0007401 pan-neural process P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0006654 phosphatidic acid biosynthesis P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0006743 ubiquinone metabolism P 0 0 0 0 0 0 2 5 0 40 -0.675 0 0 0045426 quinone cofactor biosynthesis P 0 0 0 0 0 0 2 5 0 40 -0.675 0 0 0030140 trans-Golgi network transport vesicle C 0 0 0 0 0 0 2 7 0 28.57143 -0.675 0 0 0030131 clathrin adaptor complex C 0 0 0 0 0 0 2 5 0 40 -0.675 0 0 0004666 prostaglandin-endoperoxide synthase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0042375 quinone cofactor metabolism P 0 0 0 0 0 0 2 5 0 40 -0.675 0 0 0001636 corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity F 0 0 0 0 0 0 2 4 0 50 -0.675 0 0 0008252 nucleotidase activity F 0 0 0 0 0 0 2 6 0 33.33333 -0.675 0 0 0004345 glucose-6-phosphate 1-dehydrogenase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0030057 desmosome C 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0030119 membrane coat adaptor complex C 0 0 0 0 0 0 2 5 0 40 -0.675 0 0 0004469 lysophosphatidate acyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0001530 lipopolysaccharide binding F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0008229 opsonin activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0000101 sulfur amino acid transport P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0006630 lipid binding P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0004040 amidase activity F 0 2 5 0 40 0 2 5 0 40 -0.675 0 0 0019307 mannose biosynthesis P 0 1 1 0 100 0 2 2 0 100 -0.675 0 0 0003805 blood coagulation factor XI activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0030280 structural constituent of epidermis F 0 2 9 0 22.22222 0 2 9 0 22.22222 -0.675 0 0 0007388 posterior compartment specification P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0030301 cholesterol transport P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0004365 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0004999 vasoactive intestinal polypeptide receptor activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0008247 2-acetyl-1-alkylglycerophosphocholine esterase complex C 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0000085 G2 phase of mitotic cell cycle P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0004652 polynucleotide adenylyltransferase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0007260 tyrosine phosphorylation of STAT protein P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0007262 STAT protein nuclear translocation P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0030130 clathrin coat of trans-Golgi network vesicle C 0 0 4 0 0 0 2 7 0 28.57143 -0.675 0 0 0007387 anterior compartment specification P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0030133 transport vesicle C 0 0 0 0 0 0 2 8 0 25 -0.675 0 0 0001609 adenosine receptor activity\, G-protein coupled F 0 0 0 0 0 0 2 5 0 40 -0.675 0 0 0009062 fatty acid catabolism P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0005161 platelet-derived growth factor receptor binding F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0004668 protein-arginine deiminase activity F 0 2 5 0 40 0 2 5 0 40 -0.675 0 0 0004957 prostaglandin E receptor activity F 0 2 6 0 33.33333 0 2 6 0 33.33333 -0.675 0 0 0009584 perception of visible light P 0 0 1 0 0 0 2 5 0 40 -0.675 0 0 0001515 opioid peptide activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0015333 peptide\:hydrogen symporter activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0000185 activation of MAPKKK P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0007172 signal complex formation P 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0004909 interleukin-1\, Type I\, activating receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0003955 NAD(P)H dehydrogenase (quinone) activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0005147 oncostatin-M receptor binding F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0008970 phospholipase A1 activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004176 ATP-dependent peptidase activity F 0 2 10 0 20 0 2 10 0 20 -0.675 0 0 0016998 cell wall catabolism P 0 2 15 0 13.33333 0 2 15 0 13.33333 -0.675 0 0 0004924 oncostatin-M receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004911 interleukin-2 receptor activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0003796 lysozyme activity F 0 2 9 0 22.22222 0 2 9 0 22.22222 -0.675 0 0 0004607 phosphatidylcholine-sterol O-acyltransferase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0004910 interleukin-1\, Type II\, blocking receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0006590 thyroid hormone generation P 0 2 7 0 28.57143 0 2 7 0 28.57143 -0.675 0 0 0042231 interleukin-13 biosynthesis P 0 1 1 0 100 0 2 2 0 100 -0.675 0 0 0030431 sleep P 0 1 1 0 100 0 2 2 0 100 -0.675 0 0 0042094 interleukin-2 biosynthesis P 0 1 1 0 100 0 2 2 0 100 -0.675 0 0 0045191 regulation of isotype switching P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0045650 negative regulation of macrophage differentiation P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0042326 negative regulation of phosphorylation P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0045578 negative regulation of B-cell differentiation P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0005159 insulin-like growth factor receptor binding F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0004572 mannosyl-oligosaccharide 1\,3-1\,6-alpha-mannosidase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004293 tissue kallikrein activity F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0005873 plus-end kinesin complex C 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0043026 regulation of caspase activation P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0005011 macrophage colony stimulating factor receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004692 cGMP-dependent protein kinase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0006940 regulation of smooth muscle contraction P 0 2 6 0 33.33333 0 2 6 0 33.33333 -0.675 0 0 0045884 regulation of survival gene products P 0 0 0 0 0 0 2 7 0 28.57143 -0.675 0 0 0046328 regulation of JNK cascade P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0005078 MAP-kinase scaffold activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0008337 selectin F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004797 thymidine kinase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0009798 axis specification P 0 0 0 0 0 0 2 5 0 40 -0.675 0 0 0005828 kinetochore microtubule C 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0045323 interleukin-1 receptor complex C 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0008606 phosphorylase kinase\, intrinsic catalyst activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004865 type 1 serine/threonine specific protein phosphatase inhibitor activity F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0004862 cAMP-dependent protein kinase inhibitor activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0006469 negative regulation of protein kinase activity P 0 2 5 0 40 0 2 5 0 40 -0.675 0 0 0008440 inositol-trisphosphate 3-kinase activity F 0 2 7 0 28.57143 0 2 7 0 28.57143 -0.675 0 0 0004800 thyroxine deiodinase activity F 0 2 5 0 40 0 2 5 0 40 -0.675 0 0 0030216 keratinocyte differentiation P 0 2 8 0 25 0 2 8 0 25 -0.675 0 0 0004109 coproporphyrinogen oxidase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0017028 protein stabilization activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0009412 response to heavy metal P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0008934 inositol-1(or 4)-monophosphatase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0009435 nicotinamide adenine dinucleotide biosynthesis P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0015385 sodium\:hydrogen antiporter activity F 0 2 10 0 20 0 2 10 0 20 -0.675 0 0 0016715 oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, reduced ascorbate as one donor\, and incorporation of one atom of oxygen F 0 0 0 0 0 0 2 6 0 33.33333 -0.675 0 0 0006084 acetyl-CoA metabolism P 0 2 5 0 40 0 2 7 0 28.57143 -0.675 0 0 0000302 response to reactive oxygen species P 0 1 1 0 100 0 2 2 0 100 -0.675 0 0 0004238 meprin A activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004308 exo-alpha-sialidase activity F 0 2 5 0 40 0 2 5 0 40 -0.675 0 0 0015239 multidrug transporter activity F 0 1 1 0 100 0 2 2 0 100 -0.675 0 0 0005185 neurohypophyseal hormone activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0019902 phosphatase binding F 0 0 0 0 0 0 2 5 0 40 -0.675 0 0 0016018 cyclosporin A binding F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0045161 ion channel clustering P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004972 N-methyl-D-aspartate selective glutamate receptor activity F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0001561 fatty acid alpha-oxidation P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0003973 (S)-2-hydroxy-acid oxidase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0008891 glycolate oxidase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0019903 protein phosphatase binding F 0 0 1 0 0 0 2 5 0 40 -0.675 0 0 0003696 satellite DNA binding F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0006601 creatine biosynthesis P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0000794 condensed nuclear chromosome C 0 0 1 0 0 0 2 3 0 66.66666 -0.675 0 0 0004478 methionine adenosyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004705 JUN kinase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0004199 caspase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004445 inositol-polyphosphate 5-phosphatase activity F 0 2 8 0 25 0 2 8 0 25 -0.675 0 0 0006975 DNA damage induced protein phosphorylation P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0008209 androgen metabolism P 0 0 2 0 0 0 2 5 0 40 -0.675 0 0 0007140 male meiosis P 0 1 1 0 100 0 2 2 0 100 -0.675 0 0 0017127 cholesterol transporter activity F 0 2 5 0 40 0 2 5 0 40 -0.675 0 0 0004393 heparin N-deacetylase/N-sulfotransferase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0046323 glucose import P 0 0 0 0 0 0 2 3 0 66.66666 -0.675 0 0 0005010 insulin-like growth factor receptor activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0046324 regulation of glucose import P 0 0 0 0 0 0 2 3 0 66.66666 -0.675 0 0 0005143 interleukin-12 receptor binding F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0042104 positive regulation of activated T-cell proliferation P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0016404 15-hydroxyprostaglandin dehydrogenase (NAD) activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0042093 T-helper cell differentiation P 0 1 1 0 100 0 2 3 0 66.66666 -0.675 0 0 0007339 binding of sperm to zona pellucida P 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0030224 monocyte differentiation P 0 1 1 0 100 0 2 2 0 100 -0.675 0 0 0006569 tryptophan catabolism P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004998 transferrin receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0030539 male genital morphogenesis P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0007098 centrosome cycle P 0 1 2 0 50 0 2 4 0 50 -0.675 0 0 0008450 O-sialoglycoprotein endopeptidase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0009045 xylose isomerase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0004611 phosphoenolpyruvate carboxykinase activity F 0 1 1 0 100 0 2 3 0 66.66666 -0.675 0 0 0008518 reduced folate carrier activity F 0 2 6 0 33.33333 0 2 6 0 33.33333 -0.675 0 0 0006772 thiamin metabolism P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0005338 nucleotide-sugar transporter activity F 0 1 7 0 14.28571 0 2 9 0 22.22222 -0.675 0 0 0008476 protein-tyrosine sulfotransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0030284 estrogen receptor activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0005155 epidermal growth factor receptor activating ligand activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004531 deoxyribonuclease II activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0008504 monoamine transporter activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004991 parathyroid hormone receptor activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0042476 odontogenesis P 0 1 5 0 20 0 2 6 0 33.33333 -0.675 0 0 0008367 bacterial binding F 0 1 2 0 50 0 2 3 0 66.66666 -0.675 0 0 0005108 transmembrane ephrin F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0016743 carboxyl- and carbamoyltransferase activity F 0 2 2 0 100 0 2 4 0 50 -0.675 0 0 0007483 genital disc metamorphosis P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0006423 cysteinyl-tRNA aminoacylation P 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0003803 blood coagulation factor IX activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0016291 acyl-CoA thioesterase activity F 0 1 2 0 50 0 2 3 0 66.66666 -0.675 0 0 0005172 vascular endothelial growth factor receptor binding F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004050 apyrase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0003960 NADPH\:quinone reductase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0016511 endothelin-converting enzyme activity F 0 0 1 0 0 0 2 3 0 66.66666 -0.675 0 0 0004817 cysteine-tRNA ligase activity F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0006105 succinate metabolism P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0015376 betaine/GABA\:sodium symporter activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0001607 neuromedin U receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0015840 urea transport P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0000214 tRNA-intron endonuclease complex C 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0000213 tRNA-intron endonuclease activity F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0008200 ion channel inhibitor activity F 0 2 6 0 33.33333 0 2 6 0 33.33333 -0.675 0 0 0004305 ethanolamine kinase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0005800 COPII vesicle C 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0008511 sodium\:chloride/potassium\:chloride symporter activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004234 macrophage elastase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0008431 tocopherol binding F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0016889 endodeoxyribonuclease activity\, producing other than 5’-phosphomonoesters F 0 0 0 0 0 0 2 3 0 66.66666 -0.675 0 0 0015204 urea transporter activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0008583 mystery cell fate differentiation (sensu Drosophila) P 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0019980 interleukin-5 binding F 0 0 0 0 0 0 2 3 0 66.66666 -0.675 0 0 0006388 tRNA splicing P 0 2 5 0 40 0 2 5 0 40 -0.675 0 0 0003918 DNA topoisomerase type II activity F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0015379 potassium\:chloride symporter activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0006478 peptidyl-tyrosine sulfation P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0005128 erythropoietin receptor binding F 0 1 1 0 100 0 2 2 0 100 -0.675 0 0 0016512 endothelin-converting enzyme 1 activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0001672 regulation of chromatin assembly/disassembly P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0015183 L-aspartate transporter activity F 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0005181 glycopeptide hormone F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0045671 negative regulation of osteoclast differentiation P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0008454 alpha-1\,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004613 phosphoenolpyruvate carboxykinase (GTP) activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0008525 phosphatidylcholine transporter activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0004663 RAB-protein geranylgeranyltransferase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0030520 estrogen receptor signaling pathway P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0045084 positive regulation of interleukin-12 biosynthesis P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004835 tubulin-tyrosine ligase activity F 0 2 18 0 11.11111 0 2 18 0 11.11111 -0.675 0 0 0030279 negative regulation of bone formation P 0 1 1 0 100 0 2 5 0 40 -0.675 0 0 0005084 Rab escort protein activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004062 aryl sulfotransferase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0005968 Rab-protein geranylgeranyltransferase complex C 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0016604 nuclear body C 0 1 1 0 100 0 2 4 0 50 -0.675 0 0 0045216 intercellular junction assembly and/or maintenance P 0 0 0 0 0 0 2 6 0 33.33333 -0.675 0 0 0008474 palmitoyl-(protein) hydrolase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0019214 surfactant activity F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0009597 perception of viruses P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0000175 3’-5’ exoribonuclease activity F 0 2 11 0 18.18182 0 2 11 0 18.18182 -0.675 0 0 0030538 genital morphogenesis P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0007484 genital morphogenesis (sensu Holometabola) P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0005674 transcription factor TFIIF complex C 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0004802 transketolase activity F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0042439 ethanolamine and derivative metabolism P 0 0 0 0 0 0 2 2 0 100 -0.675 0 0 0004962 endothelin receptor activity F 0 2 4 0 50 0 2 4 0 50 -0.675 0 0 0045410 positive regulation of interleukin-6 biosynthesis P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.675 0 0 0006271 DNA strand elongation P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0009598 perception of pathogenic bacteria P 0 2 2 0 100 0 2 3 0 66.66666 -0.675 0 0 0009408 response to heat P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0008220 necrosis P 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0005121 Toll binding F 0 2 2 0 100 0 2 2 0 100 -0.675 0 0 0000089 mitotic metaphase P 0 1 1 0 100 0 2 2 0 100 -0.675 0 0 0008632 apoptotic program P 1 6 9 16.66667 66.66666 3 23 35 13.04348 65.71429 -0.681 0 0 0019899 enzyme binding F 1 8 15 12.5 53.33333 3 23 38 13.04348 60.52632 -0.681 0 0 0019865 immunoglobulin binding F 0 0 0 0 0 1 10 13 10 76.92308 -0.696 0 0 0006000 fructose metabolism P 1 4 5 25 80 1 10 14 10 71.42857 -0.696 0 0 0004437 inositol/phosphatidylinositol phosphatase activity F 0 5 18 0 27.77778 1 10 27 10 37.03704 -0.696 0 0 0006471 protein amino acid ADP-ribosylation P 1 10 17 10 58.82353 1 10 17 10 58.82353 -0.696 0 0 0006809 nitric oxide biosynthesis P 1 9 13 11.11111 69.23077 1 10 14 10 71.42857 -0.696 0 0 0042446 hormone biosynthesis P 0 0 0 0 0 1 10 17 10 58.82353 -0.696 0 0 0004024 alcohol dehydrogenase activity\, zinc-dependent F 1 10 29 10 34.48276 1 10 29 10 34.48276 -0.696 0 0 0030106 MHC class I receptor activity F 1 9 24 11.11111 37.5 1 10 32 10 31.25 -0.696 0 0 0007411 axon guidance P 0 9 18 0 50 1 10 20 10 50 -0.696 0 0 0046209 nitric oxide metabolism P 0 0 0 0 0 1 10 14 10 71.42857 -0.696 0 0 0042923 neuropeptide binding F 0 0 0 0 0 1 10 22 10 45.45454 -0.696 0 0 0042770 DNA damage response\, signal transduction P 1 1 1 100 100 1 10 16 10 62.5 -0.696 0 0 0006558 L-phenylalanine metabolism P 0 1 1 0 100 1 10 11 10 90.90909 -0.696 0 0 0008188 neuropeptide receptor activity F 0 4 5 0 80 1 10 22 10 45.45454 -0.696 0 0 0046165 alcohol biosynthesis P 0 0 0 0 0 1 10 19 10 52.63158 -0.696 0 0 0019319 hexose biosynthesis P 0 0 0 0 0 1 10 19 10 52.63158 -0.696 0 0 0046364 monosaccharide biosynthesis P 0 0 0 0 0 1 10 19 10 52.63158 -0.696 0 0 0016229 steroid dehydrogenase activity F 0 0 0 0 0 1 10 18 10 55.55556 -0.696 0 0 0046942 carboxylic acid transport P 0 0 0 0 0 6 42 86 14.28571 48.83721 -0.713 0 0 0015849 organic acid transport P 0 0 0 0 0 6 42 86 14.28571 48.83721 -0.713 0 0 0009101 glycoprotein biosynthesis P 0 3 3 0 100 11 72 122 15.27778 59.01639 -0.718 0 0 0006305 DNA alkylation P 0 0 0 0 0 2 17 37 11.76471 45.94595 -0.721 0 0 0006306 DNA methylation P 2 17 37 11.76471 45.94595 2 17 37 11.76471 45.94595 -0.721 0 0 0004857 enzyme inhibitor activity F 4 11 15 36.36364 73.33334 19 119 233 15.96639 51.07296 -0.732 0 0 0004727 prenylated protein tyrosine phosphatase activity F 4 30 46 13.33333 65.21739 4 30 46 13.33333 65.21739 -0.737 0 0 0006821 chloride transport P 4 30 46 13.33333 65.21739 4 30 46 13.33333 65.21739 -0.737 0 0 0030163 protein catabolism P 4 4 5 100 80 58 341 775 17.0088 44 -0.752 0 0 0015082 di-\, tri-valent inorganic cation transporter activity F 0 0 0 0 0 3 24 28 12.5 85.71429 -0.764 0 0 0007179 TGFbeta receptor signaling pathway P 2 18 20 11.11111 90 3 24 27 12.5 88.88889 -0.764 0 0 0008514 organic anion transporter activity F 0 4 7 0 57.14286 3 24 40 12.5 60 -0.764 0 0 0006897 endocytosis P 3 30 54 10 55.55556 9 61 95 14.7541 64.21053 -0.766 0 0 0003714 transcription co-repressor activity F 8 55 83 14.54545 66.26506 8 55 83 14.54545 66.26506 -0.767 0 0 0004518 nuclease activity F 1 6 17 16.66667 35.29412 8 55 154 14.54545 35.71429 -0.767 0 0 0007276 gametogenesis P 1 2 6 50 33.33333 11 73 127 15.06849 57.48032 -0.77 0 0 0006470 protein amino acid dephosphorylation P 12 79 168 15.18987 47.02381 12 79 168 15.18987 47.02381 -0.773 0 0 0009308 amine metabolism P 0 2 3 0 66.66666 24 149 242 16.10738 61.57025 -0.776 0 0 0016327 apicolateral plasma membrane C 0 0 0 0 0 6 43 94 13.95349 45.74468 -0.778 0 0 0015929 hexosaminidase activity F 0 0 0 0 0 1 11 18 9.090909 61.11111 -0.808 0 0 0019882 antigen presentation P 0 0 1 0 0 1 11 50 9.090909 22 -0.808 0 0 0009074 aromatic amino acid family catabolism P 0 0 0 0 0 1 11 12 9.090909 91.66666 -0.808 0 0 0006570 tyrosine metabolism P 0 0 1 0 0 1 11 12 9.090909 91.66666 -0.808 0 0 0006687 glycosphingolipid metabolism P 1 4 4 25 100 1 11 12 9.090909 91.66666 -0.808 0 0 0003705 RNA polymerase II transcription factor activity\, enhancer binding F 1 11 16 9.090909 68.75 1 11 16 9.090909 68.75 -0.808 0 0 0005778 peroxisomal membrane C 0 4 6 0 66.66666 1 11 17 9.090909 64.70588 -0.808 0 0 0004022 alcohol dehydrogenase activity F 0 1 1 0 100 1 11 29 9.090909 37.93103 -0.808 0 0 0005888 proteoglycan integral to plasma membrane C 2 18 21 11.11111 85.71429 2 18 21 11.11111 85.71429 -0.813 0 0 0005180 peptide hormone F 2 18 26 11.11111 69.23077 2 18 26 11.11111 69.23077 -0.813 0 0 0019200 carbohydrate kinase activity F 0 0 0 0 0 2 18 26 11.11111 69.23077 -0.813 0 0 0008287 protein serine/threonine phosphatase complex C 0 6 13 0 46.15385 2 18 30 11.11111 60 -0.813 0 0 0017016 Ras interactor activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0048029 monosaccharide binding F 0 0 0 0 0 0 3 4 0 75 -0.827 0 0 0008533 astacin activity F 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0015087 cobalt ion transporter activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0015278 calcium-release channel activity F 0 0 3 0 0 0 3 6 0 50 -0.827 0 0 0006538 glutamate catabolism P 0 1 2 0 50 0 3 4 0 75 -0.827 0 0 0003836 beta-galactoside alpha-2\,3-sialyltransferase activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0006824 cobalt ion transport P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0003886 DNA (cytosine-5-)-methyltransferase activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0005220 inositol 1\,4\,5-triphosphate-sensitive calcium-release channel activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0007626 locomotory behavior P 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0000178 exosome (RNase complex) C 0 2 6 0 33.33333 0 3 9 0 33.33333 -0.827 0 0 0005850 eukaryotic translation initiation factor 2 complex C 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0042708 elastase activity F 0 0 0 0 0 0 3 7 0 42.85714 -0.827 0 0 0030141 secretory granule C 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0007368 determination of left/right asymmetry P 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0030178 negative regulation of Wnt receptor signaling pathway P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0006961 antibacterial humoral response (sensu Invertebrata) P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0000099 sulfur amino acid transporter activity F 0 0 0 0 0 0 3 4 0 75 -0.827 0 0 0019894 kinesin binding F 0 3 7 0 42.85714 0 3 7 0 42.85714 -0.827 0 0 0045445 myoblast differentiation P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0007219 N signaling pathway P 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0005964 phosphorylase kinase complex C 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0015813 L-glutamate transport P 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0005673 transcription factor TFIIE complex C 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0017110 nucleoside diphosphatase activity F 0 0 0 0 0 0 3 3 0 100 -0.827 0 0 0004212 lysosomal cysteine-type endopeptidase F 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0019731 antibacterial humoral response P 0 0 0 0 0 0 3 4 0 75 -0.827 0 0 0007096 regulation of exit from mitosis P 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0005099 Ras GTPase activator activity F 0 3 8 0 37.5 0 3 8 0 37.5 -0.827 0 0 0004977 melanocortin receptor activity F 0 2 4 0 50 0 3 7 0 42.85714 -0.827 0 0 0016713 oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, reduced iron-sulfur protein as one donor\, and incorporation of one atom of oxygen F 0 0 0 0 0 0 3 4 0 75 -0.827 0 0 0008339 MP kinase activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0006309 DNA fragmentation P 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0008502 melatonin receptor activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0016290 palmitoyl-CoA hydrolase activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0004720 protein-lysine 6-oxidase activity F 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0045638 negative regulation of myeloid blood cell differentiation P 0 0 0 0 0 0 3 3 0 100 -0.827 0 0 0015184 L-cystine transporter activity F 0 3 3 0 100 0 3 4 0 75 -0.827 0 0 0009791 post-embryonic development P 0 0 0 0 0 0 3 3 0 100 -0.827 0 0 0005537 mannose binding F 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0008637 apoptotic mitochondrial changes P 0 3 7 0 42.85714 0 3 7 0 42.85714 -0.827 0 0 0046887 positive regulation of hormone secretion P 0 0 0 0 0 0 3 3 0 100 -0.827 0 0 0006026 aminoglycan catabolism P 0 0 0 0 0 0 3 3 0 100 -0.827 0 0 0004559 alpha-mannosidase activity F 0 3 6 0 50 0 3 6 0 50 -0.827 0 0 0016165 lipoxygenase activity F 0 3 6 0 50 0 3 6 0 50 -0.827 0 0 0004749 ribose-phosphate diphosphokinase activity F 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0005584 collagen type I C 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0009290 cellular DNA uptake P 0 0 0 0 0 0 3 5 0 60 -0.827 0 0 0008210 estrogen metabolism P 0 2 3 0 66.66666 0 3 6 0 50 -0.827 0 0 0006921 disassembly of cell structures P 0 0 0 0 0 0 3 5 0 60 -0.827 0 0 0009411 response to UV P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0005497 androgen binding F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0030198 extracellular matrix organization and biogenesis P 0 3 7 0 42.85714 0 3 12 0 25 -0.827 0 0 0009292 genetic transfer P 0 0 0 0 0 0 3 5 0 60 -0.827 0 0 0005013 neurotrophin TRK receptor activity F 0 0 0 0 0 0 3 3 0 100 -0.827 0 0 0005594 collagen type IX C 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0001502 cartilage condensation P 0 3 8 0 37.5 0 3 8 0 37.5 -0.827 0 0 0005005 transmembrane-ephrin receptor activity F 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0009294 DNA mediated transformation P 0 0 0 0 0 0 3 5 0 60 -0.827 0 0 0009855 determination of bilateral symmetry P 0 0 0 0 0 0 3 4 0 75 -0.827 0 0 0016478 negative regulation of translation P 0 2 5 0 40 0 3 6 0 50 -0.827 0 0 0030022 adhesive extracellular matrix constituent activity F 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0004237 membrane dipeptidase activity F 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0006699 bile acid biosynthesis P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0042742 defense response to bacteria P 0 0 0 0 0 0 3 4 0 75 -0.827 0 0 0005522 profilin binding F 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0046881 positive regulation of follicle-stimulating hormone secretion P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0006027 glycosaminoglycan catabolism P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0042541 hemoglobin biosynthesis P 0 2 2 0 100 0 3 3 0 100 -0.827 0 0 0007320 insemination P 0 2 2 0 100 0 3 3 0 100 -0.827 0 0 0042092 T-helper 2 type immune response P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0009799 determination of symmetry P 0 0 0 0 0 0 3 4 0 75 -0.827 0 0 0042698 menstrual cycle P 0 0 0 0 0 0 3 3 0 100 -0.827 0 0 0004886 retinoid-X receptor activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0004948 calcitonin receptor activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0045077 negative regulation of interferon-gamma biosynthesis P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0020027 hemoglobin metabolism P 0 0 1 0 0 0 3 4 0 75 -0.827 0 0 0017022 myosin binding F 0 2 4 0 50 0 3 5 0 60 -0.827 0 0 0019377 glycolipid catabolism P 0 1 1 0 100 0 3 3 0 100 -0.827 0 0 0005610 laminin-5 C 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0015924 mannosyl-oligosaccharide mannosidase activity F 0 0 0 0 0 0 3 13 0 23.07692 -0.827 0 0 0045620 negative regulation of lymphocyte differentiation P 0 0 0 0 0 0 3 3 0 100 -0.827 0 0 0009374 biotin binding F 0 3 6 0 50 0 3 6 0 50 -0.827 0 0 0009086 methionine biosynthesis P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0001541 ovarian follicle development P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0000242 pericentriolar material C 0 2 2 0 100 0 3 6 0 50 -0.827 0 0 0004000 adenosine deaminase activity F 0 3 10 0 30 0 3 13 0 23.07692 -0.827 0 0 0015295 solute\:hydrogen symporter activity F 0 0 0 0 0 0 3 3 0 100 -0.827 0 0 0007595 lactation P 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0005000 vasopressin receptor activity F 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0003701 RNA polymerase I transcription factor activity F 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0030374 ligand-dependent nuclear receptor transcription co-activator activity F 0 3 10 0 30 0 3 10 0 30 -0.827 0 0 0004067 asparaginase activity F 0 2 4 0 50 0 3 5 0 60 -0.827 0 0 0008104 protein localization P 0 2 3 0 66.66666 0 3 4 0 75 -0.827 0 0 0004992 platelet activating factor receptor activity F 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0007011 regulation of cytoskeleton P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0005385 zinc ion transporter activity F 0 2 2 0 100 0 3 3 0 100 -0.827 0 0 0004974 leukotriene receptor activity F 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0006986 response to unfolded protein P 0 2 5 0 40 0 3 6 0 50 -0.827 0 0 0004625 calcium-dependent secreted phospholipase A2 activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0006012 galactose metabolism P 0 3 6 0 50 0 3 6 0 50 -0.827 0 0 0005094 Rho GDP-dissociation inhibitor activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0008295 spermidine biosynthesis P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0016847 1-aminocyclopropane-1-carboxylate synthase activity F 0 3 7 0 42.85714 0 3 7 0 42.85714 -0.827 0 0 0008216 spermidine metabolism P 0 0 0 0 0 0 3 3 0 100 -0.827 0 0 0016650 oxidoreductase activity\, acting on the CH-NH group of donors\, other acceptors F 0 0 0 0 0 0 3 8 0 37.5 -0.827 0 0 0006726 eye pigment biosynthesis P 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0030595 immune cell chemotaxis P 0 2 4 0 50 0 3 5 0 60 -0.827 0 0 0006029 proteoglycan metabolism P 0 1 3 0 33.33333 0 3 8 0 37.5 -0.827 0 0 0005883 neurofilament C 0 3 6 0 50 0 3 6 0 50 -0.827 0 0 0001603 vasopressin-like receptor activity F 0 0 0 0 0 0 3 5 0 60 -0.827 0 0 0009266 response to temperature P 0 0 2 0 0 0 3 8 0 37.5 -0.827 0 0 0030573 bile acid catabolism P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0008630 DNA damage response\, signal transduction resulting in induction of apoptosis P 0 3 7 0 42.85714 0 3 7 0 42.85714 -0.827 0 0 0004032 aldehyde reductase activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0007520 myoblast fusion P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0004966 galanin receptor activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0019221 cytokine and chemokine mediated signaling pathway P 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0015844 monoamine transport P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0016416 O-palmitoyltransferase activity F 0 0 0 0 0 0 3 3 0 100 -0.827 0 0 0006775 fat-soluble vitamin metabolism P 0 0 0 0 0 0 3 5 0 60 -0.827 0 0 0008580 cytoskeletal regulator activity F 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0016841 ammonia-lyase activity F 0 0 0 0 0 0 3 3 0 100 -0.827 0 0 0042809 vitamin D receptor binding F 0 3 10 0 30 0 3 10 0 30 -0.827 0 0 0004875 complement receptor activity F 0 1 1 0 100 0 3 3 0 100 -0.827 0 0 0004499 dimethylaniline monooxygenase (N-oxide-forming) activity F 0 3 6 0 50 0 3 6 0 50 -0.827 0 0 0004035 alkaline phosphatase activity F 0 3 6 0 50 0 3 6 0 50 -0.827 0 0 0004095 carnitine O-palmitoyltransferase activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0006661 phosphatidylinositol biosynthesis P 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0008122 amine oxidase (copper-containing) activity F 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0003873 6-phosphofructo-2-kinase activity F 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0006776 vitamin A metabolism P 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0007207 muscarinic acetyl choline receptor\, phospholipase C activating pathway P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0017106 activin inhibitor activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0004115 cAMP-specific phosphodiesterase activity F 0 3 7 0 42.85714 0 3 7 0 42.85714 -0.827 0 0 0007340 acrosome reaction P 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0030225 macrophage differentiation P 0 1 1 0 100 0 3 3 0 100 -0.827 0 0 0016896 exoribonuclease activity\, producing 5’-phosphomonoesters F 0 0 0 0 0 0 3 12 0 25 -0.827 0 0 0004532 exoribonuclease activity F 0 0 0 0 0 0 3 12 0 25 -0.827 0 0 0008184 glycogen phosphorylase activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0015884 folate transport P 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0004982 N-formyl peptide receptor activity F 0 3 7 0 42.85714 0 3 7 0 42.85714 -0.827 0 0 0004667 prostaglandin-D synthase activity F 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0007567 parturition P 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0015185 L-gamma-aminobutyrate transporter activity F 0 0 0 0 0 0 3 4 0 75 -0.827 0 0 0030218 erythrocyte differentiation P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0007181 TGFbeta receptor complex assembly P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0005071 transmembrane receptor protein serine/threonine kinase signaling protein activity F 0 0 0 0 0 0 3 4 0 75 -0.827 0 0 0042493 response to drug P 0 1 2 0 50 0 3 14 0 21.42857 -0.827 0 0 0004053 arginase activity F 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0008467 heparin-glucosamine 3-O-sulfotransferase activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0042116 macrophage activation P 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0042288 MHC class I protein binding F 0 3 10 0 30 0 3 10 0 30 -0.827 0 0 0042219 amino acid derivative catabolism P 0 0 0 0 0 0 3 3 0 100 -0.827 0 0 0007130 synaptonemal complex formation P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0050501 hyaluronan synthase activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0000230 nuclear mitotic chromosome C 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0015485 cholesterol binding F 0 3 7 0 42.85714 0 3 7 0 42.85714 -0.827 0 0 0007129 synapsis P 0 0 1 0 0 0 3 4 0 75 -0.827 0 0 0000238 zygotene P 0 0 0 0 0 0 3 4 0 75 -0.827 0 0 0000038 very-long-chain fatty acid metabolism P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0007217 tachykinin signaling pathway P 0 3 9 0 33.33333 0 3 9 0 33.33333 -0.827 0 0 0005415 nucleoside\:sodium symporter activity F 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0008519 ammonium transporter activity F 0 3 13 0 23.07692 0 3 13 0 23.07692 -0.827 0 0 0006526 arginine biosynthesis P 0 3 7 0 42.85714 0 3 7 0 42.85714 -0.827 0 0 0007528 neuromuscular junction development P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0009075 histidine family amino acid metabolism P 0 0 0 0 0 0 3 5 0 60 -0.827 0 0 0046488 phosphatidylinositol metabolism P 0 0 0 0 0 0 3 4 0 75 -0.827 0 0 0045190 isotype switching P 0 1 1 0 100 0 3 3 0 100 -0.827 0 0 0008651 actin polymerizing activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0019079 viral genome replication P 0 1 2 0 50 0 3 4 0 75 -0.827 0 0 0003956 NAD(P)-arginine ADP-ribosyltransferase activity F 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0030641 hydrogen ion homeostasis P 0 0 0 0 0 0 3 14 0 21.42857 -0.827 0 0 0006547 histidine metabolism P 0 1 1 0 100 0 3 5 0 60 -0.827 0 0 0004942 anaphylatoxin receptor activity F 0 0 0 0 0 0 3 3 0 100 -0.827 0 0 0015347 sodium-independent organic anion transporter activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0045768 positive regulation of anti-apoptosis P 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0003809 thrombin activity F 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0007638 mechanosensory behavior P 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0006885 regulation of pH P 0 3 14 0 21.42857 0 3 14 0 21.42857 -0.827 0 0 0005332 GABA\:sodium symporter activity F 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0008035 high-density lipoprotein binding F 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0016899 oxidoreductase activity\, acting on the CH-OH group of donors\, oxygen as acceptor F 0 0 0 0 0 0 3 3 0 100 -0.827 0 0 0015889 vitamin B12 transport P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0007168 receptor guanylyl cyclase signaling pathway P 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0008075 receptor guanylate cyclase activity F 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0004873 asialoglycoprotein receptor activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0045134 uridine diphosphatase activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0042441 eye pigment metabolism P 0 0 0 0 0 0 3 4 0 75 -0.827 0 0 0015277 kainate selective glutamate receptor activity F 0 3 8 0 37.5 0 3 8 0 37.5 -0.827 0 0 0003876 AMP deaminase activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0030282 bone mineralization P 0 2 7 0 28.57143 0 3 13 0 23.07692 -0.827 0 0 0006432 phenylalanyl-tRNA aminoacylation P 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0004826 phenylalanine-tRNA ligase activity F 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0005088 Ras guanyl-nucleotide exchange factor activity F 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0042562 hormone binding F 0 0 0 0 0 0 3 3 0 100 -0.827 0 0 0004103 choline kinase activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0004465 lipoprotein lipase activity F 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0008486 diphosphoinositol-polyphosphate diphosphatase activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0004185 serine carboxypeptidase activity F 0 0 2 0 0 0 3 5 0 60 -0.827 0 0 0008023 transcription elongation factor complex C 0 3 5 0 60 0 3 5 0 60 -0.827 0 0 0006517 protein deglycosylation P 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0004937 alpha1-adrenergic receptor activity F 0 3 6 0 50 0 3 6 0 50 -0.827 0 0 0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system P 0 3 14 0 21.42857 0 3 14 0 21.42857 -0.827 0 0 0015279 store-operated calcium channel activity F 0 3 4 0 75 0 3 4 0 75 -0.827 0 0 0004597 peptide-aspartate beta-dioxygenase activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0030295 protein kinase activator activity F 0 1 1 0 100 0 3 6 0 50 -0.827 0 0 0008095 inositol-1\,4\,5-triphosphate receptor activity F 0 3 3 0 100 0 3 3 0 100 -0.827 0 0 0005072 TGFbeta receptor\, cytoplasmic mediator activity F 0 2 2 0 100 0 3 4 0 75 -0.827 0 0 0030169 low-density lipoprotein binding F 0 2 2 0 100 0 3 5 0 60 -0.827 0 0 0009057 macromolecule catabolism P 0 0 0 0 0 60 356 797 16.85393 44.6675 -0.846 0 0 0016772 transferase activity\, transferring phosphorus-containing groups F 1 3 5 33.33333 60 81 474 1063 17.08861 44.59078 -0.849 0 0 0009056 catabolism P 0 1 1 0 100 86 502 1047 17.13147 47.94651 -0.85 0 0 0016298 lipase activity F 0 0 0 0 0 5 38 89 13.1579 42.69663 -0.858 0 0 0008509 anion transporter activity F 0 2 3 0 66.66666 5 38 92 13.1579 41.30435 -0.858 0 0 0004721 protein phosphatase activity F 1 10 23 10 43.47826 15 99 201 15.15152 49.25373 -0.877 0 0 0008081 phosphoric diester hydrolase activity F 0 0 0 0 0 4 32 90 12.5 35.55556 -0.883 0 0 0015101 organic cation transporter activity F 0 5 5 0 100 2 19 36 10.52632 52.77778 -0.901 0 0 0007193 G-protein signaling\, adenylate cyclase inhibiting pathway P 0 5 7 0 71.42857 2 19 24 10.52632 79.16666 -0.901 0 0 0007420 brain development P 2 19 28 10.52632 67.85714 2 19 28 10.52632 67.85714 -0.901 0 0 0016917 GABA receptor activity F 0 0 0 0 0 1 12 28 8.333333 42.85714 -0.911 0 0 0005212 structural constituent of eye lens F 1 12 17 8.333333 70.58823 1 12 17 8.333333 70.58823 -0.911 0 0 0019439 aromatic compound catabolism P 0 0 0 0 0 1 12 13 8.333333 92.30769 -0.911 0 0 0016641 oxidoreductase activity\, acting on the CH-NH2 group of donors\, oxygen as acceptor F 0 0 0 0 0 1 12 16 8.333333 75 -0.911 0 0 0006953 acute-phase response P 1 12 18 8.333333 66.66666 1 12 18 8.333333 66.66666 -0.911 0 0 0008601 protein phosphatase type 2A\, intrinsic regulator activity F 1 12 18 8.333333 66.66666 1 12 18 8.333333 66.66666 -0.911 0 0 0004890 GABA-A receptor activity F 1 12 24 8.333333 50 1 12 24 8.333333 50 -0.911 0 0 0016247 channel regulator activity F 0 0 0 0 0 1 12 23 8.333333 52.17391 -0.911 0 0 0030333 antigen processing P 0 0 0 0 0 1 12 51 8.333333 23.52941 -0.911 0 0 0007229 integrin-mediated signaling pathway P 3 26 39 11.53846 66.66666 3 26 39 11.53846 66.66666 -0.922 0 0 0016051 carbohydrate biosynthesis P 1 6 15 16.66667 40 5 39 70 12.82051 55.71429 -0.923 0 0 0006865 amino acid transport P 3 24 57 12.5 42.10526 4 33 69 12.12121 47.82609 -0.953 0 0 0007588 excretion P 4 27 32 14.81481 84.375 4 33 40 12.12121 82.5 -0.953 0 0 0009127 purine nucleoside monophosphate biosynthesis P 0 0 0 0 0 0 4 14 0 28.57143 -0.955 0 0 0016865 intramolecular isomerase activity\, other intramolecular oxidoreductases F 0 0 0 0 0 0 4 7 0 57.14286 -0.955 0 0 0004955 prostaglandin receptor activity F 0 0 0 0 0 0 4 10 0 40 -0.955 0 0 0004116 cGMP-specific phosphodiesterase activity F 0 4 6 0 66.66666 0 4 6 0 66.66666 -0.955 0 0 0003799 antifungal peptide activity F 0 4 11 0 36.36364 0 4 11 0 36.36364 -0.955 0 0 0008133 collagenase activity F 0 3 3 0 100 0 4 5 0 80 -0.955 0 0 0019722 calcium-mediated signaling P 0 4 5 0 80 0 4 5 0 80 -0.955 0 0 0004740 [pyruvate dehydrogenase (lipoamide)] kinase activity F 0 4 4 0 100 0 4 4 0 100 -0.955 0 0 0015695 organic cation transport P 0 4 4 0 100 0 4 4 0 100 -0.955 0 0 0030262 apoptotic nuclear changes P 0 0 0 0 0 0 4 6 0 66.66666 -0.955 0 0 0000060 protein-nucleus import\, translocation P 0 4 4 0 100 0 4 4 0 100 -0.955 0 0 0005104 fibroblast growth factor receptor binding F 0 0 0 0 0 0 4 8 0 50 -0.955 0 0 0004157 dihydropyrimidinase activity F 0 4 4 0 100 0 4 4 0 100 -0.955 0 0 0004287 prolyl oligopeptidase activity F 0 4 8 0 50 0 4 8 0 50 -0.955 0 0 0030353 fibroblast growth factor receptor antagonist activity F 0 0 0 0 0 0 4 8 0 50 -0.955 0 0 0004274 dipeptidyl-peptidase IV activity F 0 4 10 0 40 0 4 10 0 40 -0.955 0 0 0009126 purine nucleoside monophosphate metabolism P 0 0 0 0 0 0 4 14 0 28.57143 -0.955 0 0 0006536 glutamate metabolism P 0 0 1 0 0 0 4 11 0 36.36364 -0.955 0 0 0019002 GMP binding F 0 0 0 0 0 0 4 5 0 80 -0.955 0 0 0008585 female gonad development P 0 1 1 0 100 0 4 4 0 100 -0.955 0 0 0009167 purine ribonucleoside monophosphate metabolism P 0 0 0 0 0 0 4 14 0 28.57143 -0.955 0 0 0005375 copper ion transporter activity F 0 2 3 0 66.66666 0 4 5 0 80 -0.955 0 0 0015174 basic amino acid transporter activity F 0 3 4 0 75 0 4 5 0 80 -0.955 0 0 0050671 positive regulation of lymphocyte proliferation P 0 0 0 0 0 0 4 7 0 57.14286 -0.955 0 0 0045619 regulation of lymphocyte differentiation P 0 0 0 0 0 0 4 5 0 80 -0.955 0 0 0005080 protein kinase C binding F 0 4 7 0 57.14286 0 4 7 0 57.14286 -0.955 0 0 0004708 MAP kinase kinase activity F 0 4 9 0 44.44444 0 4 9 0 44.44444 -0.955 0 0 0005160 transforming growth factor-beta receptor binding F 0 4 7 0 57.14286 0 4 7 0 57.14286 -0.955 0 0 0015359 amino acid permease activity F 0 3 8 0 37.5 0 4 9 0 44.44444 -0.955 0 0 0046882 negative regulation of follicle-stimulating hormone secretion P 0 4 4 0 100 0 4 4 0 100 -0.955 0 0 0007452 imaginal disc metamorphosis P 0 0 0 0 0 0 4 6 0 66.66666 -0.955 0 0 0030004 monovalent inorganic cation homeostasis P 0 0 0 0 0 0 4 15 0 26.66667 -0.955 0 0 0046888 negative regulation of hormone secretion P 0 0 0 0 0 0 4 5 0 80 -0.955 0 0 0042434 indole derivative metabolism P 0 0 0 0 0 0 4 7 0 57.14286 -0.955 0 0 0004065 arylsulfatase activity F 0 4 5 0 80 0 4 5 0 80 -0.955 0 0 0042430 indole and derivative metabolism P 0 0 0 0 0 0 4 7 0 57.14286 -0.955 0 0 0004245 neprilysin activity F 0 4 8 0 50 0 4 8 0 50 -0.955 0 0 0045026 plasma membrane fusion P 0 0 0 0 0 0 4 6 0 66.66666 -0.955 0 0 0030193 regulation of blood coagulation P 0 0 0 0 0 0 4 4 0 100 -0.955 0 0 0001504 neurotransmitter uptake P 0 4 4 0 100 0 4 4 0 100 -0.955 0 0 0006586 indolalkylamine metabolism P 0 0 0 0 0 0 4 7 0 57.14286 -0.955 0 0 0007286 spermatid development P 0 4 6 0 66.66666 0 4 6 0 66.66666 -0.955 0 0 0004126 cytidine deaminase activity F 0 4 4 0 100 0 4 4 0 100 -0.955 0 0 0006003 fructose 2\,6-bisphosphate metabolism P 0 4 5 0 80 0 4 5 0 80 -0.955 0 0 0005086 ARF guanyl-nucleotide exchange factor activity F 0 4 7 0 57.14286 0 4 7 0 57.14286 -0.955 0 0 0042036 negative regulation of cytokine biosynthesis P 0 1 1 0 100 0 4 4 0 100 -0.955 0 0 0015270 dihydropyridine-sensitive calcium channel activity F 0 4 4 0 100 0 4 4 0 100 -0.955 0 0 0005313 L-glutamate transporter activity F 0 2 3 0 66.66666 0 4 6 0 66.66666 -0.955 0 0 0008294 calcium/calmodulin-responsive adenylate cyclase activity F 0 4 10 0 40 0 4 10 0 40 -0.955 0 0 0006283 transcription-coupled nucleotide-excision repair P 0 4 4 0 100 0 4 4 0 100 -0.955 0 0 0008286 insulin receptor signaling pathway P 0 4 7 0 57.14286 0 4 7 0 57.14286 -0.955 0 0 0016339 calcium-dependent cell-cell adhesion P 0 3 6 0 50 0 4 7 0 57.14286 -0.955 0 0 0016854 racemase and epimerase activity F 0 0 0 0 0 0 4 8 0 50 -0.955 0 0 0015321 sodium-dependent phosphate transporter activity F 0 4 5 0 80 0 4 5 0 80 -0.955 0 0 0001619 lysosphingolipid and lysophosphatidic acid receptor activity F 0 4 10 0 40 0 4 10 0 40 -0.955 0 0 0007263 nitric oxide mediated signal transduction P 0 4 5 0 80 0 4 5 0 80 -0.955 0 0 0005152 interleukin-1 receptor antagonist activity F 0 4 8 0 50 0 4 8 0 50 -0.955 0 0 0008503 benzodiazepine receptor activity F 0 4 7 0 57.14286 0 4 7 0 57.14286 -0.955 0 0 0004945 angiotensin type II receptor activity F 0 4 6 0 66.66666 0 4 6 0 66.66666 -0.955 0 0 0030195 negative regulation of blood coagulation P 0 4 4 0 100 0 4 4 0 100 -0.955 0 0 0015491 cation\:cation antiporter activity F 0 0 0 0 0 0 4 16 0 25 -0.955 0 0 0004033 aldo-keto reductase activity F 0 4 8 0 50 0 4 8 0 50 -0.955 0 0 0004712 protein threonine/tyrosine kinase activity F 0 0 0 0 0 0 4 9 0 44.44444 -0.955 0 0 0042803 protein homodimerization activity F 0 4 6 0 66.66666 0 4 6 0 66.66666 -0.955 0 0 0030553 3’\,5’-cGMP binding F 0 4 5 0 80 0 4 5 0 80 -0.955 0 0 0045072 regulation of interferon-gamma biosynthesis P 0 0 0 0 0 0 4 5 0 80 -0.955 0 0 0042287 MHC protein binding F 0 0 8 0 0 0 4 19 0 21.05263 -0.955 0 0 0046884 follicle-stimulating hormone secretion P 0 0 0 0 0 0 4 4 0 100 -0.955 0 0 0019841 retinol binding F 0 4 8 0 50 0 4 8 0 50 -0.955 0 0 0005154 epidermal growth factor receptor binding F 0 2 3 0 66.66666 0 4 5 0 80 -0.955 0 0 0004745 retinol dehydrogenase activity F 0 4 4 0 100 0 4 4 0 100 -0.955 0 0 0042347 negative regulation of NF-kappaB-nucleus import P 0 0 0 0 0 0 4 4 0 100 -0.955 0 0 0042306 regulation of protein-nucleus import P 0 0 0 0 0 0 4 4 0 100 -0.955 0 0 0004703 G-protein coupled receptor kinase activity F 0 4 7 0 57.14286 0 4 7 0 57.14286 -0.955 0 0 0004936 alpha-adrenergic receptor activity F 0 0 0 0 0 0 4 9 0 44.44444 -0.955 0 0 0006568 tryptophan metabolism P 0 1 1 0 100 0 4 5 0 80 -0.955 0 0 0042345 regulation of NF-kappaB-nucleus import P 0 0 0 0 0 0 4 4 0 100 -0.955 0 0 0042135 neurotransmitter catabolism P 0 4 6 0 66.66666 0 4 6 0 66.66666 -0.955 0 0 0016884 carbon-nitrogen ligase activity\, with glutamine as amido-N-donor F 0 0 0 0 0 0 4 8 0 50 -0.955 0 0 0042990 regulation of transcription factor-nucleus import P 0 0 0 0 0 0 4 4 0 100 -0.955 0 0 0005593 facit collagen C 0 0 0 0 0 0 4 7 0 57.14286 -0.955 0 0 0009067 aspartate family amino acid biosynthesis P 0 0 0 0 0 0 4 4 0 100 -0.955 0 0 0015926 glucosidase activity F 0 0 0 0 0 0 4 6 0 66.66666 -0.955 0 0 0016286 small conductance calcium-activated potassium channel activity F 0 4 5 0 80 0 4 5 0 80 -0.955 0 0 0016634 oxidoreductase activity\, acting on the CH-CH group of donors\, oxygen as acceptor F 0 0 0 0 0 0 4 11 0 36.36364 -0.955 0 0 0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity F 0 4 4 0 100 0 4 4 0 100 -0.955 0 0 0046883 regulation of hormone secretion P 0 0 0 0 0 0 4 5 0 80 -0.955 0 0 0045125 bioactive lipid receptor activity F 0 0 0 0 0 0 4 10 0 40 -0.955 0 0 0005006 epidermal growth factor receptor activity F 0 4 8 0 50 0 4 8 0 50 -0.955 0 0 0005031 tumor necrosis factor receptor activity F 0 3 3 0 100 0 4 4 0 100 -0.955 0 0 0008038 neuronal cell recognition P 0 4 5 0 80 0 4 5 0 80 -0.955 0 0 0030159 receptor signaling complex scaffold activity F 0 2 4 0 50 0 4 8 0 50 -0.955 0 0 0016597 amino acid binding F 0 4 8 0 50 0 4 8 0 50 -0.955 0 0 0000160 two-component signal transduction system (phosphorelay) P 0 4 13 0 30.76923 0 4 13 0 30.76923 -0.955 0 0 0046879 hormone secretion P 0 0 0 0 0 0 4 9 0 44.44444 -0.955 0 0 0008243 plasminogen activator activity F 0 2 2 0 100 0 4 4 0 100 -0.955 0 0 0004931 ATP-gated cation channel activity F 0 4 4 0 100 0 4 4 0 100 -0.955 0 0 0046880 regulation of follicle-stimulating hormone secretion P 0 0 0 0 0 0 4 4 0 100 -0.955 0 0 0015467 G-protein activated inward rectifier potassium channel activity F 0 4 4 0 100 0 4 4 0 100 -0.955 0 0 0005021 vascular endothelial growth factor receptor activity F 0 4 6 0 66.66666 0 4 6 0 66.66666 -0.955 0 0 0016289 CoA hydrolase activity F 0 0 0 0 0 0 4 6 0 66.66666 -0.955 0 0 0008158 hedgehog receptor activity F 0 4 7 0 57.14286 0 4 7 0 57.14286 -0.955 0 0 0042992 negative regulation of transcription factor-nucleus import P 0 0 0 0 0 0 4 4 0 100 -0.955 0 0 0015302 uncoupling protein activity F 0 4 4 0 100 0 4 4 0 100 -0.955 0 0 0006349 imprinting P 0 4 4 0 100 0 4 4 0 100 -0.955 0 0 0030111 regulation of Wnt receptor signaling pathway P 0 1 2 0 50 0 4 5 0 80 -0.955 0 0 0016455 RNA polymerase II transcription mediator activity F 0 4 11 0 36.36364 0 4 11 0 36.36364 -0.955 0 0 0005853 eukaryotic translation elongation factor 1 complex C 0 4 6 0 66.66666 0 4 6 0 66.66666 -0.955 0 0 0046822 regulation of nucleocytoplasmic transport P 0 0 0 0 0 0 4 4 0 100 -0.955 0 0 0016778 diphosphotransferase activity F 0 0 0 0 0 0 4 6 0 66.66666 -0.955 0 0 0006829 zinc ion transport P 0 4 5 0 80 0 4 5 0 80 -0.955 0 0 0030149 sphingolipid catabolism P 0 1 1 0 100 0 4 6 0 66.66666 -0.955 0 0 0006706 steroid catabolism P 0 0 1 0 0 0 4 8 0 50 -0.955 0 0 0009008 DNA-methyltransferase activity F 0 1 1 0 100 0 4 4 0 100 -0.955 0 0 0019209 kinase activator activity F 0 1 1 0 100 0 4 7 0 57.14286 -0.955 0 0 0007342 fusion of sperm to egg plasma membrane P 0 4 5 0 80 0 4 5 0 80 -0.955 0 0 0018212 peptidyl-tyrosine modification P 0 0 0 0 0 0 4 5 0 80 -0.955 0 0 0006637 acyl-CoA metabolism P 0 4 6 0 66.66666 0 4 6 0 66.66666 -0.955 0 0 0015800 acidic amino acid transport P 0 1 1 0 100 0 4 5 0 80 -0.955 0 0 0042102 positive regulation of T-cell proliferation P 0 2 4 0 50 0 4 7 0 57.14286 -0.955 0 0 0004030 aldehyde dehydrogenase [NAD(P)] activity F 0 4 5 0 80 0 4 5 0 80 -0.955 0 0 0009795 embryonic morphogenesis P 0 0 0 0 0 0 4 7 0 57.14286 -0.955 0 0 0001595 angiotensin receptor activity F 0 0 0 0 0 0 4 6 0 66.66666 -0.955 0 0 0007253 cytoplasmic sequestering of NF-kappaB P 0 4 4 0 100 0 4 4 0 100 -0.955 0 0 0042994 cytoplasmic sequestering of transcription factor P 0 0 0 0 0 0 4 4 0 100 -0.955 0 0 0009168 purine ribonucleoside monophosphate biosynthesis P 0 4 7 0 57.14286 0 4 14 0 28.57143 -0.955 0 0 0042423 catecholamine biosynthesis P 0 4 5 0 80 0 4 5 0 80 -0.955 0 0 0005112 Notch binding F 0 4 5 0 80 0 4 5 0 80 -0.955 0 0 0004016 adenylate cyclase activity F 0 0 1 0 0 0 4 11 0 36.36364 -0.955 0 0 0042348 NF-kappaB protein-nucleus import P 0 0 0 0 0 0 4 4 0 100 -0.955 0 0 0042308 negative regulation of protein-nucleus import P 0 0 0 0 0 0 4 4 0 100 -0.955 0 0 0004806 triacylglycerol lipase activity F 0 4 10 0 40 0 4 10 0 40 -0.955 0 0 0042991 transcription factor-nucleus import P 0 0 0 0 0 0 4 4 0 100 -0.955 0 0 0007213 acetyl choline receptor signaling\, muscarinic pathway P 0 4 4 0 100 0 4 4 0 100 -0.955 0 0 0046823 negative regulation of nucleocytoplasmic transport P 0 0 0 0 0 0 4 4 0 100 -0.955 0 0 0007568 aging P 0 3 5 0 60 0 4 6 0 66.66666 -0.955 0 0 0000119 mediator complex C 0 3 11 0 27.27273 0 4 12 0 33.33333 -0.955 0 0 0008138 protein tyrosine/serine/threonine phosphatase activity F 2 14 38 14.28571 36.84211 2 20 53 10 37.73585 -0.985 0 0 0009072 aromatic amino acid family metabolism P 0 5 9 0 55.55556 2 20 25 10 80 -0.985 0 0 0005911 intercellular junction C 3 11 19 27.27273 57.89474 5 40 90 12.5 44.44444 -0.987 0 0 0005516 calmodulin binding F 8 58 100 13.7931 58 8 59 101 13.55932 58.41584 -0.991 0 0 0016049 cell growth P 5 17 29 29.41176 58.62069 8 59 95 13.55932 62.10526 -0.991 0 0 0006915 apoptosis P 22 130 214 16.92308 60.74767 40 248 388 16.12903 63.91753 -1 0 0 0008134 transcription factor binding F 3 9 17 33.33333 52.94118 26 167 241 15.56886 69.29461 -1.004 0 0 0008080 N-acetyltransferase activity F 1 10 19 10 52.63158 1 13 24 7.692307 54.16667 -1.008 0 0 0016637 oxidoreductase activity\, acting on the CH-CH group of donors\, other acceptors F 0 0 0 0 0 1 13 20 7.692307 65 -1.008 0 0 0046456 icosanoid biosynthesis P 0 0 0 0 0 1 13 17 7.692307 76.47059 -1.008 0 0 0016638 oxidoreductase activity\, acting on the CH-NH2 group of donors F 0 0 0 0 0 1 13 19 7.692307 68.42105 -1.008 0 0 0008021 synaptic vesicle C 1 13 44 7.692307 29.54545 1 13 44 7.692307 29.54545 -1.008 0 0 0015034 cytochrome P450 activity F 1 13 25 7.692307 52 1 13 25 7.692307 52 -1.008 0 0 0005272 sodium channel activity F 0 1 2 0 50 1 13 28 7.692307 46.42857 -1.008 0 0 0006664 glycolipid metabolism P 0 0 1 0 0 1 13 16 7.692307 81.25 -1.008 0 0 0000271 polysaccharide biosynthesis P 0 0 0 0 0 1 13 22 7.692307 59.09091 -1.008 0 0 0007409 axonogenesis P 0 3 9 0 33.33333 1 13 28 7.692307 46.42857 -1.008 0 0 0001633 secretin-like receptor activity F 0 0 0 0 0 1 13 23 7.692307 56.52174 -1.008 0 0 0005515 protein binding F 52 325 725 16 44.82759 136 789 1500 17.23701 52.6 -1.009 0 0 0009100 glycoprotein metabolism P 0 0 1 0 0 11 78 130 14.10256 60 -1.017 0 0 0006811 ion transport P 8 127 201 6.299212 63.18408 57 346 738 16.47399 46.88347 -1.02 0 0 0012501 programmed cell death P 0 0 0 0 0 40 249 388 16.06426 64.17525 -1.028 0 0 0016705 oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen F 0 0 0 0 0 8 60 102 13.33333 58.82353 -1.044 0 0 0007417 central nervous system development P 6 41 63 14.63415 65.07937 8 60 92 13.33333 65.21739 -1.044 0 0 0004177 aminopeptidase activity F 0 12 16 0 75 2 21 36 9.523809 58.33333 -1.066 0 0 0005126 hematopoietin/interferon-class (D200-domain) cytokine receptor binding F 0 2 10 0 20 2 21 46 9.523809 45.65217 -1.066 0 0 0007254 JNK cascade P 0 12 18 0 66.66666 2 21 30 9.523809 70 -1.066 0 0 0015370 solute\:sodium symporter activity F 0 0 0 0 0 2 21 39 9.523809 53.84615 -1.066 0 0 0016702 oxidoreductase activity\, acting on single donors with incorporation of molecular oxygen\, incorporation of two atoms of oxygen F 2 12 20 16.66667 60 2 21 33 9.523809 63.63636 -1.066 0 0 0046058 cAMP metabolism P 0 0 0 0 0 0 5 12 0 41.66667 -1.068 0 0 0015248 sterol transporter activity F 0 3 3 0 100 0 5 8 0 62.5 -1.068 0 0 0046068 cGMP metabolism P 0 0 0 0 0 0 5 9 0 55.55556 -1.068 0 0 0042108 positive regulation of cytokine biosynthesis P 0 0 0 0 0 0 5 7 0 71.42857 -1.068 0 0 0006477 protein amino acid sulfation P 0 3 4 0 75 0 5 6 0 83.33334 -1.068 0 0 0015427 ABC-type efflux porter activity F 0 0 0 0 0 0 5 7 0 71.42857 -1.068 0 0 0003708 retinoic acid receptor activity F 0 2 6 0 33.33333 0 5 9 0 55.55556 -1.068 0 0 0006890 retrograde (Golgi to ER) transport P 0 5 6 0 83.33334 0 5 6 0 83.33334 -1.068 0 0 0006171 cAMP biosynthesis P 0 5 12 0 41.66667 0 5 12 0 41.66667 -1.068 0 0 0050670 regulation of lymphocyte proliferation P 0 0 0 0 0 0 5 10 0 50 -1.068 0 0 0006584 catecholamine metabolism P 0 1 5 0 20 0 5 10 0 50 -1.068 0 0 0004953 icosanoid receptor activity F 0 0 0 0 0 0 5 12 0 41.66667 -1.068 0 0 0045637 regulation of myeloid blood cell differentiation P 0 1 3 0 33.33333 0 5 7 0 71.42857 -1.068 0 0 0006182 cGMP biosynthesis P 0 5 9 0 55.55556 0 5 9 0 55.55556 -1.068 0 0 0007212 dopamine receptor signaling pathway P 0 5 5 0 100 0 5 5 0 100 -1.068 0 0 0019958 C-X-C chemokine binding F 0 0 0 0 0 0 5 6 0 83.33334 -1.068 0 0 0007589 fluid secretion P 0 5 7 0 71.42857 0 5 7 0 71.42857 -1.068 0 0 0004522 pancreatic ribonuclease activity F 0 5 17 0 29.41176 0 5 17 0 29.41176 -1.068 0 0 0015172 acidic amino acid transporter activity F 0 1 1 0 100 0 5 7 0 71.42857 -1.068 0 0 0042129 regulation of T-cell proliferation P 0 0 1 0 0 0 5 9 0 55.55556 -1.068 0 0 0030521 androgen receptor signaling pathway P 0 5 12 0 41.66667 0 5 12 0 41.66667 -1.068 0 0 0048019 receptor antagonist activity F 0 1 1 0 100 0 5 9 0 55.55556 -1.068 0 0 0004952 dopamine receptor activity F 0 5 9 0 55.55556 0 5 9 0 55.55556 -1.068 0 0 0016812 hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds\, in cyclic amides F 0 1 3 0 33.33333 0 5 9 0 55.55556 -1.068 0 0 0030168 platelet activation P 0 5 8 0 62.5 0 5 8 0 62.5 -1.068 0 0 0004954 prostanoid receptor activity F 0 0 0 0 0 0 5 12 0 41.66667 -1.068 0 0 0015057 thrombin receptor activity F 0 5 6 0 83.33334 0 5 6 0 83.33334 -1.068 0 0 0030308 negative regulation of cell growth P 0 5 7 0 71.42857 0 5 7 0 71.42857 -1.068 0 0 0042098 T-cell proliferation P 0 0 0 0 0 0 5 9 0 55.55556 -1.068 0 0 0007444 imaginal disc development P 0 0 0 0 0 0 5 7 0 71.42857 -1.068 0 0 0004091 carboxylesterase activity F 0 0 2 0 0 0 5 14 0 35.71429 -1.068 0 0 0046457 prostanoid biosynthesis P 0 0 0 0 0 0 5 6 0 83.33334 -1.068 0 0 0004673 protein-histidine kinase activity F 0 0 0 0 0 0 5 10 0 50 -1.068 0 0 0004887 thyroid hormone receptor activity F 0 5 7 0 71.42857 0 5 7 0 71.42857 -1.068 0 0 0004396 hexokinase activity F 0 5 8 0 62.5 0 5 8 0 62.5 -1.068 0 0 0019864 IgG binding F 0 5 7 0 71.42857 0 5 7 0 71.42857 -1.068 0 0 0030547 receptor inhibitor activity F 0 0 0 0 0 0 5 9 0 55.55556 -1.068 0 0 0004194 pepsin A activity F 0 5 16 0 31.25 0 5 16 0 31.25 -1.068 0 0 0001516 prostaglandin biosynthesis P 0 5 6 0 83.33334 0 5 6 0 83.33334 -1.068 0 0 0008191 metalloendopeptidase inhibitor activity F 0 5 6 0 83.33334 0 5 6 0 83.33334 -1.068 0 0 0004981 muscarinic acetylcholine receptor activity F 0 5 7 0 71.42857 0 5 7 0 71.42857 -1.068 0 0 0004969 histamine receptor activity F 0 5 9 0 55.55556 0 5 9 0 55.55556 -1.068 0 0 0004759 serine esterase activity F 0 5 11 0 45.45454 0 5 11 0 45.45454 -1.068 0 0 0006572 tyrosine catabolism P 0 5 5 0 100 0 5 5 0 100 -1.068 0 0 0018958 phenol metabolism P 0 0 0 0 0 0 5 10 0 50 -1.068 0 0 0043009 embryonic development (sensu Vertebrata) P 0 0 0 0 0 0 5 6 0 83.33334 -1.068 0 0 0042095 interferon-gamma biosynthesis P 0 2 2 0 100 0 5 6 0 83.33334 -1.068 0 0 0009890 negative regulation of biosynthesis P 0 0 0 0 0 0 5 8 0 62.5 -1.068 0 0 0000155 two-component sensor molecule activity F 0 5 10 0 50 0 5 10 0 50 -1.068 0 0 0009892 negative regulation of metabolism P 0 0 0 0 0 0 5 9 0 55.55556 -1.068 0 0 0015923 mannosidase activity F 0 0 1 0 0 0 5 18 0 27.77778 -1.068 0 0 0003719 transcription factor binding\, cytoplasmic sequestering F 0 5 6 0 83.33334 0 5 6 0 83.33334 -1.068 0 0 0008366 nerve ensheathment P 0 4 5 0 80 0 5 6 0 83.33334 -1.068 0 0 0005452 inorganic anion exchanger activity F 0 5 25 0 20 0 5 25 0 20 -1.068 0 0 0042551 nerve maturation P 0 0 0 0 0 0 5 6 0 83.33334 -1.068 0 0 0008499 UDP-galactose beta-N-acetylglucosamine beta-1\,3-galactosyltransferase activity F 0 5 6 0 83.33334 0 5 6 0 83.33334 -1.068 0 0 0004303 estradiol 17-beta-dehydrogenase activity F 0 5 7 0 71.42857 0 5 7 0 71.42857 -1.068 0 0 0042802 protein self binding F 0 0 0 0 0 0 5 7 0 71.42857 -1.068 0 0 0004960 thromboxane receptor activity F 0 4 11 0 36.36364 0 5 12 0 41.66667 -1.068 0 0 0000188 inactivation of MAPK P 0 5 11 0 45.45454 0 5 11 0 45.45454 -1.068 0 0 0015029 internalization receptor activity F 0 5 6 0 83.33334 0 5 6 0 83.33334 -1.068 0 0 0030545 receptor regulator activity F 0 0 0 0 0 0 5 9 0 55.55556 -1.068 0 0 0016406 carnitine O-acyltransferase activity F 0 0 0 0 0 0 5 5 0 100 -1.068 0 0 0005035 death receptor activity F 0 1 1 0 100 0 5 5 0 100 -1.068 0 0 0000050 urea cycle P 0 5 7 0 71.42857 0 5 7 0 71.42857 -1.068 0 0 0030217 T-cell differentiation P 0 2 4 0 50 0 5 8 0 62.5 -1.068 0 0 0016805 dipeptidase activity F 0 2 3 0 66.66666 0 5 9 0 55.55556 -1.068 0 0 0015106 bicarbonate transporter activity F 0 0 0 0 0 0 5 25 0 20 -1.068 0 0 0005089 Rho guanyl-nucleotide exchange factor activity F 0 5 10 0 50 0 5 10 0 50 -1.068 0 0 0015301 anion\:anion antiporter activity F 0 0 0 0 0 0 5 25 0 20 -1.068 0 0 0004331 fructose-2\,6-bisphosphate 2-phosphatase activity F 0 5 7 0 71.42857 0 5 7 0 71.42857 -1.068 0 0 0015238 drug transporter activity F 0 2 4 0 50 0 5 15 0 33.33333 -1.068 0 0 0000097 sulfur amino acid biosynthesis P 0 0 0 0 0 0 5 6 0 83.33334 -1.068 0 0 0015380 anion exchanger activity F 0 0 0 0 0 0 5 25 0 20 -1.068 0 0 0006491 N-glycan processing P 0 5 6 0 83.33334 0 5 6 0 83.33334 -1.068 0 0 0001701 embryonic development (sensu Mammalia) P 0 5 6 0 83.33334 0 5 6 0 83.33334 -1.068 0 0 0016494 C-X-C chemokine receptor activity F 0 4 4 0 100 0 5 6 0 83.33334 -1.068 0 0 0003713 transcription co-activator activity F 13 90 119 14.44444 75.63025 13 92 131 14.13043 70.229 -1.098 0 0 0005605 basal lamina C 0 3 5 0 60 1 14 22 7.142857 63.63636 -1.099 0 0 0005530 lectin F 1 14 19 7.142857 73.68421 1 14 19 7.142857 73.68421 -1.099 0 0 0005164 tumor necrosis factor receptor binding F 1 14 23 7.142857 60.86956 1 14 23 7.142857 60.86956 -1.099 0 0 0007631 feeding behavior P 1 13 19 7.692307 68.42105 1 14 20 7.142857 70 -1.099 0 0 0008217 regulation of blood pressure P 1 14 26 7.142857 53.84615 1 14 26 7.142857 53.84615 -1.099 0 0 0005242 inward rectifier potassium channel activity F 1 9 13 11.11111 69.23077 1 14 20 7.142857 70 -1.099 0 0 0008373 sialyltransferase activity F 1 8 14 12.5 57.14286 1 14 42 7.142857 33.33333 -1.099 0 0 0016764 transferase activity\, transferring other glycosyl groups F 0 0 0 0 0 1 14 42 7.142857 33.33333 -1.099 0 0 0000267 cell fraction C 0 0 1 0 0 86 514 717 16.73152 71.68758 -1.103 0 0 0004725 protein tyrosine phosphatase activity F 1 14 40 7.142857 35 5 42 89 11.90476 47.19101 -1.112 0 0 0042127 regulation of cell proliferation P 0 3 9 0 33.33333 22 147 243 14.96599 60.49383 -1.13 0 0 0006807 nitrogen metabolism P 1 8 14 12.5 57.14286 3 29 46 10.34483 63.04348 -1.139 0 0 0007178 transmembrane receptor protein serine/threonine kinase signaling pathway P 0 6 7 0 85.71429 3 29 33 10.34483 87.87878 -1.139 0 0 0016701 oxidoreductase activity\, acting on single donors with incorporation of molecular oxygen F 0 1 1 0 100 2 22 34 9.090909 64.70588 -1.143 0 0 0008235 metalloexopeptidase activity F 1 3 10 33.33333 30 4 36 81 11.11111 44.44444 -1.151 0 0 0008285 negative regulation of cell proliferation P 11 80 120 13.75 66.66666 11 81 122 13.58025 66.39344 -1.158 0 0 0003712 transcription cofactor activity F 4 18 27 22.22222 66.66666 24 160 227 15 70.48458 -1.169 0 0 0007215 glutamate signaling pathway P 0 6 10 0 60 0 6 11 0 54.54546 -1.169 0 0 0030173 integral to Golgi membrane C 0 6 9 0 66.66666 0 6 9 0 66.66666 -1.169 0 0 0006308 DNA catabolism P 0 3 4 0 75 0 6 9 0 66.66666 -1.169 0 0 0006516 glycoprotein catabolism P 0 3 4 0 75 0 6 7 0 85.71429 -1.169 0 0 0004908 interleukin-1 receptor activity F 0 2 3 0 66.66666 0 6 7 0 85.71429 -1.169 0 0 0046966 thyroid hormone receptor binding F 0 6 18 0 33.33333 0 6 18 0 33.33333 -1.169 0 0 0000077 DNA damage response\, signal transduction resulting in cell cycle arrest P 0 4 6 0 66.66666 0 6 9 0 66.66666 -1.169 0 0 0001709 cell fate determination P 0 3 4 0 75 0 6 9 0 66.66666 -1.169 0 0 0006688 glycosphingolipid biosynthesis P 0 6 7 0 85.71429 0 6 7 0 85.71429 -1.169 0 0 0004985 opioid receptor activity F 0 2 4 0 50 0 6 11 0 54.54546 -1.169 0 0 0019966 interleukin-1 binding F 0 0 0 0 0 0 6 7 0 85.71429 -1.169 0 0 0016806 dipeptidyl-peptidase and tripeptidyl-peptidase activity F 0 0 0 0 0 0 6 12 0 50 -1.169 0 0 0005344 oxygen transporter activity F 0 6 18 0 33.33333 0 6 18 0 33.33333 -1.169 0 0 0015671 oxygen transport P 0 6 18 0 33.33333 0 6 18 0 33.33333 -1.169 0 0 0004935 adrenoceptor activity F 0 4 9 0 44.44444 0 6 12 0 50 -1.169 0 0 0015108 chloride transporter activity F 0 1 2 0 50 0 6 27 0 22.22222 -1.169 0 0 0004928 frizzled receptor activity F 0 6 6 0 100 0 6 6 0 100 -1.169 0 0 0003730 mRNA 3’ UTR binding F 0 6 7 0 85.71429 0 6 7 0 85.71429 -1.169 0 0 0007271 synaptic transmission\, cholinergic P 0 5 6 0 83.33334 0 6 7 0 85.71429 -1.169 0 0 0005583 fibrillar collagen C 0 0 0 0 0 0 6 9 0 66.66666 -1.169 0 0 0046395 carboxylic acid catabolism P 0 0 0 0 0 0 6 6 0 100 -1.169 0 0 0006527 arginine catabolism P 0 6 7 0 85.71429 0 6 7 0 85.71429 -1.169 0 0 0016054 organic acid catabolism P 0 0 0 0 0 0 6 6 0 100 -1.169 0 0 0003810 protein-glutamine gamma-glutamyltransferase activity F 0 6 8 0 75 0 6 8 0 75 -1.169 0 0 0015296 anion\:cation symporter activity F 0 0 0 0 0 0 6 6 0 100 -1.169 0 0 0019203 carbohydrate phosphatase activity F 0 0 0 0 0 0 6 8 0 75 -1.169 0 0 0015070 toxin activity F 0 6 9 0 66.66666 0 6 9 0 66.66666 -1.169 0 0 0006024 glycosaminoglycan biosynthesis P 0 6 7 0 85.71429 0 6 9 0 66.66666 -1.169 0 0 0015669 gas transport P 0 0 0 0 0 0 6 18 0 33.33333 -1.169 0 0 0015377 cation\:chloride symporter activity F 0 1 1 0 100 0 6 6 0 100 -1.169 0 0 0017017 MAP kinase phosphatase activity F 0 6 15 0 40 0 6 15 0 40 -1.169 0 0 0045596 negative regulation of cell differentiation P 0 0 0 0 0 0 6 7 0 85.71429 -1.169 0 0 0015807 L-amino acid transport P 0 0 0 0 0 0 6 9 0 66.66666 -1.169 0 0 0003823 antigen binding F 0 4 147 0 2.721088 0 6 159 0 3.773585 -1.169 0 0 0007270 nerve-nerve synaptic transmission P 0 0 3 0 0 0 6 10 0 60 -1.169 0 0 0009792 embryonic development (sensu Animalia) P 0 0 0 0 0 0 6 12 0 50 -1.169 0 0 0005626 insoluble fraction C 0 6 10 0 60 0 6 10 0 60 -1.169 0 0 0016909 SAP kinase activity F 0 0 0 0 0 0 6 7 0 85.71429 -1.169 0 0 0004415 hyalurononglucosaminidase activity F 0 6 13 0 46.15385 0 6 13 0 46.15385 -1.169 0 0 0006814 sodium ion transport P 5 43 91 11.62791 47.25275 5 43 91 11.62791 47.25275 -1.172 0 0 0045202 synaptic junction C 1 13 29 7.692307 44.82759 1 15 33 6.666667 45.45454 -1.185 0 0 0004112 cyclic-nucleotide phosphodiesterase activity F 0 0 0 0 0 1 15 41 6.666667 36.58537 -1.185 0 0 0004114 3’\,5’-cyclic-nucleotide phosphodiesterase activity F 0 7 21 0 33.33333 1 15 40 6.666667 37.5 -1.185 0 0 0008016 regulation of heart rate P 1 15 22 6.666667 68.18182 1 15 22 6.666667 68.18182 -1.185 0 0 0016564 transcriptional repressor activity F 1 14 31 7.142857 45.16129 1 15 37 6.666667 40.54054 -1.185 0 0 0042445 hormone metabolism P 0 0 0 0 0 1 15 34 6.666667 44.11765 -1.185 0 0 0007205 protein kinase C activation P 1 15 24 6.666667 62.5 1 15 24 6.666667 62.5 -1.185 0 0 0005044 scavenger receptor activity F 1 15 33 6.666667 45.45454 1 15 33 6.666667 45.45454 -1.185 0 0 0006508 proteolysis and peptidolysis P 22 251 592 8.76494 42.39865 54 336 769 16.07143 43.69311 -1.199 0 0 0030234 enzyme regulator activity F 0 1 4 0 25 46 290 534 15.86207 54.30712 -1.204 0 0 0007565 pregnancy P 1 19 47 5.263158 40.42553 2 23 52 8.695652 44.23077 -1.218 0 0 0016301 kinase activity F 22 77 164 28.57143 46.95122 73 447 1022 16.3311 43.73777 -1.249 0 0 0005342 organic acid transporter activity F 0 0 0 0 0 6 51 100 11.76471 51 -1.251 0 0 0016789 carboxylic ester hydrolase activity F 0 1 1 0 100 6 51 116 11.76471 43.96552 -1.251 0 0 0046943 carboxylic acid transporter activity F 0 0 0 0 0 6 51 100 11.76471 51 -1.251 0 0 0016813 hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds\, in linear amidines F 0 0 0 0 0 0 7 11 0 63.63636 -1.263 0 0 0016526 G-protein coupled receptor activity\, unknown ligand F 0 7 17 0 41.17647 0 7 17 0 41.17647 -1.263 0 0 0005243 gap-junction forming channel activity F 0 0 0 0 0 0 7 22 0 31.81818 -1.263 0 0 0004190 aspartic-type endopeptidase activity F 0 2 16 0 12.5 0 7 32 0 21.875 -1.263 0 0 0015250 water channel activity F 0 7 7 0 100 0 7 7 0 100 -1.263 0 0 0001565 phorbol ester receptor activity F 0 0 0 0 0 0 7 10 0 70 -1.263 0 0 0004435 phosphoinositide phospholipase C activity F 0 7 25 0 28 0 7 25 0 28 -1.263 0 0 0042044 fluid transport P 0 0 0 0 0 0 7 7 0 100 -1.263 0 0 0015280 amiloride-sensitive sodium channel activity F 0 7 11 0 63.63636 0 7 11 0 63.63636 -1.263 0 0 0019886 antigen processing\, exogenous antigen via MHC class II P 0 7 34 0 20.58824 0 7 34 0 20.58824 -1.263 0 0 0004434 inositol/phosphatidylinositol phosphodiesterase activity F 0 0 0 0 0 0 7 25 0 28 -1.263 0 0 0030518 steroid hormone receptor signaling pathway P 0 0 0 0 0 0 7 15 0 46.66667 -1.263 0 0 0009247 glycolipid biosynthesis P 0 1 1 0 100 0 7 9 0 77.77778 -1.263 0 0 0005863 striated muscle thick filament C 0 7 15 0 46.66667 0 7 15 0 46.66667 -1.263 0 0 0007516 hemocyte development P 0 6 8 0 75 0 7 9 0 77.77778 -1.263 0 0 0016892 endoribonuclease activity\, producing other than 5’-phosphomonoesters F 0 0 0 0 0 0 7 21 0 33.33333 -1.263 0 0 0009893 positive regulation of metabolism P 0 0 0 0 0 0 7 11 0 63.63636 -1.263 0 0 0030522 intracellular receptor-mediated signaling pathway P 0 0 0 0 0 0 7 15 0 46.66667 -1.263 0 0 0009891 positive regulation of biosynthesis P 0 0 0 0 0 0 7 11 0 63.63636 -1.263 0 0 0030148 sphingolipid biosynthesis P 0 0 0 0 0 0 7 9 0 77.77778 -1.263 0 0 0045165 cell fate commitment P 0 0 0 0 0 0 7 10 0 70 -1.263 0 0 0008206 bile acid metabolism P 0 2 3 0 66.66666 0 7 8 0 87.5 -1.263 0 0 0006833 water transport P 0 7 7 0 100 0 7 7 0 100 -1.263 0 0 0015269 calcium-activated potassium channel activity F 0 3 15 0 20 0 7 20 0 35 -1.263 0 0 0005579 membrane attack complex C 0 7 7 0 100 0 7 7 0 100 -1.263 0 0 0006023 aminoglycan biosynthesis P 0 1 1 0 100 0 7 10 0 70 -1.263 0 0 0030183 B-cell differentiation P 0 5 10 0 50 0 7 12 0 58.33333 -1.263 0 0 0019884 antigen presentation\, exogenous antigen P 0 7 34 0 20.58824 0 7 34 0 20.58824 -1.263 0 0 0019840 isoprenoid binding F 0 0 0 0 0 0 7 12 0 58.33333 -1.263 0 0 0005501 retinoid binding F 0 3 4 0 75 0 7 12 0 58.33333 -1.263 0 0 0005542 folic acid binding F 0 7 11 0 63.63636 0 7 11 0 63.63636 -1.263 0 0 0004697 protein kinase C activity F 0 5 6 0 83.33334 0 7 10 0 70 -1.263 0 0 0018149 peptide cross-linking P 0 7 10 0 70 0 7 10 0 70 -1.263 0 0 0009596 perception of pest/pathogen/parasite P 0 3 7 0 42.85714 0 7 13 0 53.84615 -1.263 0 0 0015285 connexon channel activity F 0 7 22 0 31.81818 0 7 22 0 31.81818 -1.263 0 0 0015025 GPI-anchored membrane-bound receptor F 0 7 10 0 70 0 7 10 0 70 -1.263 0 0 0009595 perception of biotic stimulus P 0 0 0 0 0 0 7 13 0 53.84615 -1.263 0 0 0005922 connexon complex C 0 7 22 0 31.81818 0 7 22 0 31.81818 -1.263 0 0 0004182 carboxypeptidase A activity F 1 16 41 6.25 39.02439 1 16 41 6.25 39.02439 -1.267 0 0 0005326 neurotransmitter transporter activity F 0 0 1 0 0 1 16 30 6.25 53.33333 -1.267 0 0 0005923 tight junction C 1 16 37 6.25 43.24324 1 16 37 6.25 43.24324 -1.267 0 0 0004181 metallocarboxypeptidase activity F 0 0 1 0 0 1 16 42 6.25 38.09524 -1.267 0 0 0005070 SH3/SH2 adaptor protein activity F 3 31 42 9.67742 73.80952 3 31 42 9.67742 73.80952 -1.274 0 0 0015837 amine/polyamine transport P 0 0 0 0 0 4 38 75 10.52632 50.66667 -1.276 0 0 0000003 reproduction P 0 0 0 0 0 12 90 153 13.33333 58.82353 -1.282 0 0 0019953 sexual reproduction P 0 0 0 0 0 12 90 153 13.33333 58.82353 -1.282 0 0 0019992 diacylglycerol binding F 2 24 31 8.333333 77.41936 2 24 31 8.333333 77.41936 -1.29 0 0 0006958 complement activation\, classical pathway P 2 24 27 8.333333 88.88889 2 24 27 8.333333 88.88889 -1.29 0 0 0016481 negative regulation of transcription P 3 12 24 25 50 6 52 94 11.53846 55.31915 -1.306 0 0 0008202 steroid metabolism P 2 17 34 11.76471 50 10 78 133 12.82051 58.64662 -1.31 0 0 0008544 epidermal differentiation P 4 39 61 10.25641 63.93443 4 39 61 10.25641 63.93443 -1.336 0 0 0005069 transmembrane receptor protein tyrosine kinase docking protein activity F 0 1 1 0 100 3 32 43 9.375 74.4186 -1.339 0 0 0007188 G-protein signaling\, coupled to cAMP nucleotide second messenger P 1 16 21 6.25 76.19048 5 46 59 10.86957 77.9661 -1.345 0 0 0019933 cAMP-mediated signaling P 0 0 0 0 0 5 46 59 10.86957 77.9661 -1.345 0 0 0045595 regulation of cell differentiation P 0 2 3 0 66.66666 1 17 23 5.882353 73.91304 -1.345 0 0 0008375 acetylglucosaminyltransferase activity F 0 2 7 0 28.57143 1 17 26 5.882353 65.38461 -1.345 0 0 0015459 potassium channel regulator activity F 0 8 15 0 53.33333 0 8 15 0 53.33333 -1.351 0 0 0015259 glutamate channel activity F 0 0 0 0 0 0 8 26 0 30.76923 -1.351 0 0 0015256 monocarboxylate channel activity F 0 0 0 0 0 0 8 26 0 30.76923 -1.351 0 0 0008395 steroid hydroxylase activity F 0 2 3 0 66.66666 0 8 14 0 57.14286 -1.351 0 0 0015020 glucuronosyltransferase activity F 0 4 18 0 22.22222 0 8 25 0 32 -1.351 0 0 0005978 glycogen biosynthesis P 0 8 10 0 80 0 8 10 0 80 -1.351 0 0 0030099 myeloid blood cell differentiation P 0 1 1 0 100 0 8 11 0 72.72727 -1.351 0 0 0007515 lymph gland development P 0 1 2 0 50 0 8 11 0 72.72727 -1.351 0 0 0016755 transferase activity\, transferring amino-acyl groups F 0 0 0 0 0 0 8 17 0 47.05882 -1.351 0 0 0005149 interleukin-1 receptor binding F 0 4 4 0 100 0 8 12 0 66.66666 -1.351 0 0 0005027 NGF/TNF (6 C-domain) receptor activity F 0 4 4 0 100 0 8 8 0 100 -1.351 0 0 0009250 glucan biosynthesis P 0 0 0 0 0 0 8 10 0 80 -1.351 0 0 0004970 inotropic glutamate receptor activity F 0 4 13 0 30.76923 0 8 25 0 32 -1.351 0 0 0008034 lipoprotein binding F 0 3 4 0 75 0 8 14 0 57.14286 -1.351 0 0 0008484 sulfuric ester hydrolase activity F 0 1 9 0 11.11111 0 8 18 0 44.44444 -1.351 0 0 0045012 MHC class II receptor activity F 0 8 36 0 22.22222 0 8 36 0 22.22222 -1.351 0 0 0007162 negative regulation of cell adhesion P 0 7 10 0 70 0 8 11 0 72.72727 -1.351 0 0 0005234 glutamate-gated ion channel activity F 0 8 26 0 30.76923 0 8 26 0 30.76923 -1.351 0 0 0009315 drug resistance P 0 8 12 0 66.66666 0 8 12 0 66.66666 -1.351 0 0 0005079 protein kinase A anchoring activity F 0 8 12 0 66.66666 0 8 12 0 66.66666 -1.351 0 0 0016310 phosphorylation P 1 9 15 11.11111 60 52 331 779 15.70997 42.49037 -1.363 0 0 0007167 enzyme linked receptor protein signaling pathway P 0 1 1 0 100 12 92 140 13.04348 65.71429 -1.368 0 0 0015171 amino acid transporter activity F 2 5 5 40 100 4 40 77 10 51.94805 -1.395 0 0 0008219 cell death P 2 10 12 20 83.33334 41 268 414 15.29851 64.7343 -1.397 0 0 0007517 muscle development P 10 66 112 15.15152 58.92857 10 80 132 12.5 60.60606 -1.401 0 0 0005882 intermediate filament C 1 28 82 3.571429 34.14634 3 33 90 9.090909 36.66667 -1.401 0 0 0005066 transmembrane receptor protein tyrosine kinase signaling protein activity F 0 0 1 0 0 3 33 47 9.090909 70.21277 -1.401 0 0 0045111 intermediate filament cytoskeleton C 0 0 0 0 0 3 33 90 9.090909 36.66667 -1.401 0 0 0016791 phosphoric monoester hydrolase activity F 0 0 0 0 0 19 137 283 13.86861 48.40989 -1.424 0 0 0046649 lymphocyte activation P 0 0 0 0 0 2 26 44 7.692307 59.09091 -1.427 0 0 0048232 male gamete generation P 0 0 0 0 0 7 61 100 11.47541 61 -1.428 0 0 0007283 spermatogenesis P 7 57 95 12.2807 60 7 61 101 11.47541 60.39604 -1.428 0 0 0005892 nicotinic acetylcholine-gated receptor-channel complex C 0 9 12 0 75 0 9 12 0 75 -1.433 0 0 0042087 cell-mediated immune response P 0 0 0 0 0 0 9 12 0 75 -1.433 0 0 0016066 cellular defense response (sensu Vertebrata) P 0 0 5 0 0 0 9 17 0 52.94118 -1.433 0 0 0015145 monosaccharide transporter activity F 0 0 0 0 0 0 9 16 0 56.25 -1.433 0 0 0007202 phospholipase C activation P 0 9 14 0 64.28571 0 9 14 0 64.28571 -1.433 0 0 0005251 delayed rectifier potassium channel activity F 0 9 10 0 90 0 9 10 0 90 -1.433 0 0 0006525 arginine metabolism P 0 1 1 0 100 0 9 14 0 64.28571 -1.433 0 0 0008378 galactosyltransferase activity F 0 3 12 0 25 0 9 21 0 42.85714 -1.433 0 0 0005653 perinuclear space C 0 9 13 0 69.23077 0 9 13 0 69.23077 -1.433 0 0 0042088 T-helper 1 type immune response P 0 3 5 0 60 0 9 12 0 75 -1.433 0 0 0015149 hexose transporter activity F 0 0 0 0 0 0 9 16 0 56.25 -1.433 0 0 0016849 phosphorus-oxygen lyase activity F 0 0 0 0 0 0 9 22 0 40.90909 -1.433 0 0 0008239 dipeptidyl-peptidase activity F 0 6 11 0 54.54546 0 9 20 0 45 -1.433 0 0 0007222 frizzled signaling pathway P 0 9 19 0 47.36842 0 9 19 0 47.36842 -1.433 0 0 0015026 coreceptor activity F 0 9 13 0 69.23077 0 9 13 0 69.23077 -1.433 0 0 0006692 prostanoid metabolism P 0 0 0 0 0 0 9 12 0 75 -1.433 0 0 0004383 guanylate cyclase activity F 0 9 20 0 45 0 9 20 0 45 -1.433 0 0 0005355 glucose transporter activity F 0 8 13 0 61.53846 0 9 15 0 60 -1.433 0 0 0006693 prostaglandin metabolism P 0 4 6 0 66.66666 0 9 12 0 75 -1.433 0 0 0006796 phosphate metabolism P 2 10 17 20 58.82353 66 417 961 15.82734 43.3923 -1.476 0 0 0006793 phosphorus metabolism P 0 0 0 0 0 66 417 961 15.82734 43.3923 -1.476 0 0 0016265 death P 0 0 0 0 0 41 271 419 15.12915 64.6778 -1.479 0 0 0005245 voltage-gated calcium channel activity F 1 13 24 7.692307 54.16667 1 19 31 5.263158 61.29032 -1.492 0 0 0009566 fertilization P 0 0 0 0 0 1 19 29 5.263158 65.51724 -1.492 0 0 0007338 fertilization (sensu Animalia) P 1 11 17 9.090909 64.70588 1 19 29 5.263158 65.51724 -1.492 0 0 0006690 icosanoid metabolism P 0 1 2 0 50 1 19 28 5.263158 67.85714 -1.492 0 0 0000187 activation of MAPK P 0 10 16 0 62.5 0 10 16 0 62.5 -1.51 0 0 0003995 acyl-CoA dehydrogenase activity F 0 7 8 0 87.5 0 10 13 0 76.92308 -1.51 0 0 0005184 neuropeptide hormone activity F 0 8 16 0 50 0 10 18 0 55.55556 -1.51 0 0 0015758 glucose transport P 0 8 9 0 88.88889 0 10 12 0 83.33334 -1.51 0 0 0004707 MAP kinase activity F 0 10 16 0 62.5 0 10 16 0 62.5 -1.51 0 0 0003797 antibacterial peptide activity F 0 10 15 0 66.66666 0 10 16 0 62.5 -1.51 0 0 0000051 urea cycle intermediate metabolism P 0 0 0 0 0 0 10 15 0 66.66666 -1.51 0 0 0003993 acid phosphatase activity F 0 10 21 0 47.61905 0 10 21 0 47.61905 -1.51 0 0 0015749 monosaccharide transport P 0 0 0 0 0 0 10 12 0 83.33334 -1.51 0 0 0030574 collagen catabolism P 0 10 17 0 58.82353 0 10 17 0 58.82353 -1.51 0 0 0042035 regulation of cytokine biosynthesis P 0 2 3 0 66.66666 0 10 13 0 76.92308 -1.51 0 0 0008067 metabotropic glutamate\, GABA-B-like receptor activity F 0 10 28 0 35.71429 0 10 32 0 31.25 -1.51 0 0 0004179 membrane alanyl aminopeptidase activity F 0 10 14 0 71.42857 0 10 14 0 71.42857 -1.51 0 0 0008014 calcium-dependent cell adhesion molecule activity F 0 10 13 0 76.92308 0 10 13 0 76.92308 -1.51 0 0 0042110 T-cell activation P 0 2 6 0 33.33333 0 10 19 0 52.63158 -1.51 0 0 0030693 caspase activity F 0 10 17 0 58.82353 0 10 17 0 58.82353 -1.51 0 0 0008645 hexose transport P 0 0 0 0 0 0 10 12 0 83.33334 -1.51 0 0 0009190 cyclic nucleotide biosynthesis P 0 0 0 0 0 0 10 21 0 47.61905 -1.51 0 0 0006957 complement activation\, alternative pathway P 0 10 12 0 83.33334 0 10 12 0 83.33334 -1.51 0 0 0016284 alanine aminopeptidase activity F 0 0 0 0 0 0 10 14 0 71.42857 -1.51 0 0 0015294 solute\:cation symporter activity F 0 1 1 0 100 2 28 47 7.142857 59.57447 -1.556 0 0 0016064 humoral defense mechanism (sensu Vertebrata) P 0 0 1 0 0 2 28 35 7.142857 80 -1.556 0 0 0006956 complement activation P 0 0 1 0 0 2 28 34 7.142857 82.35294 -1.556 0 0 0006928 cell motility P 14 83 107 16.86747 77.57009 27 190 290 14.21053 65.51724 -1.561 0 0 0005275 amine/polyamine transporter activity F 0 0 0 0 0 5 50 89 10 56.17978 -1.561 0 0 0005507 copper ion binding F 1 20 47 5 42.55319 1 20 47 5 42.55319 -1.561 0 0 0006805 xenobiotic metabolism P 1 20 58 5 34.48276 1 20 58 5 34.48276 -1.561 0 0 0004714 transmembrane receptor protein tyrosine kinase activity F 1 18 30 5.555555 60 4 43 76 9.302325 56.57895 -1.565 0 0 0007398 ectoderm development P 0 4 9 0 44.44444 4 43 70 9.302325 61.42857 -1.565 0 0 0004993 serotonin receptor activity F 0 11 13 0 84.61539 0 11 13 0 84.61539 -1.584 0 0 0007602 phototransduction P 0 8 21 0 38.09524 0 11 27 0 40.74074 -1.584 0 0 0004926 non-G-protein coupled 7TM receptor activity F 0 7 12 0 58.33333 0 11 20 0 55 -1.584 0 0 0007623 circadian rhythm P 0 9 11 0 81.81818 0 11 13 0 84.61539 -1.584 0 0 0004889 nicotinic acetylcholine-activated cation-selective channel activity F 0 11 18 0 61.11111 0 11 18 0 61.11111 -1.584 0 0 0005076 receptor signaling protein serine/threonine kinase signaling protein activity F 0 1 2 0 50 0 11 17 0 64.70588 -1.584 0 0 0007203 phosphatidylinositol-4\,5-bisphosphate hydrolysis P 0 11 13 0 84.61539 0 11 13 0 84.61539 -1.584 0 0 0009618 response to pathogenic bacteria P 0 9 10 0 90 0 11 13 0 84.61539 -1.584 0 0 0009065 glutamine family amino acid catabolism P 0 0 0 0 0 0 11 18 0 61.11111 -1.584 0 0 0006968 cellular defense response P 5 42 69 11.90476 60.86956 5 51 86 9.803922 59.30233 -1.613 0 0 0005539 glycosaminoglycan binding F 0 3 4 0 75 5 51 81 9.803922 62.96296 -1.613 0 0 0009410 response to xenobiotic stimulus P 0 1 2 0 50 1 21 60 4.761905 35 -1.628 0 0 0016055 Wnt receptor signaling pathway P 0 0 0 0 0 1 21 45 4.761905 46.66667 -1.628 0 0 0000004 biological_process unknown P 51 336 838 15.17857 40.09547 51 336 838 15.17857 40.09547 -1.631 0 0 0006493 O-linked glycosylation P 0 12 17 0 70.58823 0 12 17 0 70.58823 -1.655 0 0 0004675 transmembrane receptor protein serine/threonine kinase activity F 0 0 0 0 0 0 12 19 0 63.15789 -1.655 0 0 0007416 synaptogenesis P 0 11 16 0 68.75 0 12 17 0 70.58823 -1.655 0 0 0019239 deaminase activity F 0 1 3 0 33.33333 0 12 25 0 48 -1.655 0 0 0005024 transforming growth factor-beta receptor activity F 0 11 16 0 68.75 0 12 19 0 63.15789 -1.655 0 0 0030098 lymphocyte differentiation P 0 0 0 0 0 0 12 20 0 60 -1.655 0 0 0019835 cytolysis P 0 11 15 0 73.33334 0 12 19 0 63.15789 -1.655 0 0 0007519 myogenesis P 0 6 6 0 100 0 12 17 0 70.58823 -1.655 0 0 0009187 cyclic nucleotide metabolism P 0 2 6 0 33.33333 0 12 27 0 44.44444 -1.655 0 0 0016798 hydrolase activity\, acting on glycosyl bonds F 3 22 43 13.63636 51.16279 5 52 134 9.615385 38.80597 -1.664 0 0 0008201 heparin binding F 3 38 54 7.894737 70.37037 3 38 54 7.894737 70.37037 -1.695 0 0 0007605 hearing P 5 53 81 9.433962 65.4321 5 53 81 9.433962 65.4321 -1.714 0 0 0009592 perception of sound P 0 0 1 0 0 5 53 80 9.433962 66.25 -1.714 0 0 0030695 GTPase regulator activity F 0 0 1 0 0 15 120 225 12.5 53.33333 -1.72 0 0 0019198 transmembrane receptor protein phosphatase activity F 0 0 0 0 0 0 13 18 0 72.22222 -1.722 0 0 0016493 C-C chemokine receptor activity F 0 13 20 0 65 0 13 20 0 65 -1.722 0 0 0001503 ossification P 0 10 17 0 58.82353 0 13 27 0 48.14815 -1.722 0 0 0046849 bone remodeling P 0 0 0 0 0 0 13 27 0 48.14815 -1.722 0 0 0030155 regulation of cell adhesion P 0 5 6 0 83.33334 0 13 17 0 76.47059 -1.722 0 0 0005001 transmembrane receptor protein tyrosine phosphatase activity F 0 13 18 0 72.22222 0 13 18 0 72.22222 -1.722 0 0 0015179 L-amino acid transporter activity F 0 0 0 0 0 0 13 18 0 72.22222 -1.722 0 0 0019957 C-C chemokine binding F 0 0 0 0 0 0 13 20 0 65 -1.722 0 0 0030203 glycosaminoglycan metabolism P 0 4 8 0 50 0 13 20 0 65 -1.722 0 0 0042578 phosphoric ester hydrolase activity F 0 2 3 0 66.66666 22 165 366 13.33333 45.08197 -1.745 0 0 0004896 hematopoietin/interferon-class (D200-domain) cytokine receptor activity F 3 18 47 16.66667 38.29787 3 39 73 7.692307 53.42466 -1.749 0 0 0006950 response to stress P 6 39 62 15.38461 62.90322 75 482 802 15.56017 60.09975 -1.751 0 0 0015203 polyamine transporter activity F 0 0 0 0 0 1 23 56 4.347826 41.07143 -1.755 0 0 0006836 neurotransmitter transport P 0 18 36 0 50 1 23 42 4.347826 54.76191 -1.755 0 0 0005279 amino acid-polyamine transporter activity F 1 20 47 5 42.55319 1 23 56 4.347826 41.07143 -1.755 0 0 0005520 insulin-like growth factor binding F 0 14 22 0 63.63636 0 14 22 0 63.63636 -1.787 0 0 0016502 nucleotide receptor activity F 0 0 0 0 0 0 14 35 0 40 -1.787 0 0 0001614 purinergic nucleotide receptor activity F 0 0 0 0 0 0 14 35 0 40 -1.787 0 0 0001608 nucleotide receptor activity\, G-protein coupled F 0 0 0 0 0 0 14 35 0 40 -1.787 0 0 0006022 aminoglycan metabolism P 0 0 0 0 0 0 14 21 0 66.66666 -1.787 0 0 0007622 rhythmic behavior P 0 3 5 0 60 0 14 19 0 73.68421 -1.787 0 0 0042107 cytokine metabolism P 0 0 0 0 0 0 14 17 0 82.35294 -1.787 0 0 0045028 purinergic nucleotide receptor activity\, G-protein coupled F 0 11 28 0 39.28571 0 14 35 0 40 -1.787 0 0 0003801 blood coagulation factor activity F 0 5 5 0 100 0 14 16 0 87.5 -1.787 0 0 0009617 response to bacteria P 0 1 3 0 33.33333 0 14 19 0 73.68421 -1.787 0 0 0042089 cytokine biosynthesis P 0 1 1 0 100 0 14 17 0 82.35294 -1.787 0 0 0004702 receptor signaling protein serine/threonine kinase activity F 0 3 3 0 100 2 32 48 6.25 66.66666 -1.794 0 0 0045321 cell activation P 0 1 2 0 50 2 32 53 6.25 60.37736 -1.794 0 0 0000122 negative regulation of transcription from Pol II promoter P 3 40 53 7.5 75.47169 3 40 53 7.5 75.47169 -1.803 0 0 0005319 lipid transporter activity F 1 24 36 4.166667 66.66666 3 40 69 7.5 57.97102 -1.803 0 0 0004180 carboxypeptidase activity F 1 15 25 6.666667 60 1 24 56 4.166667 42.85714 -1.816 0 0 0000165 MAPKKK cascade P 1 6 8 16.66667 75 1 24 39 4.166667 61.53846 -1.816 0 0 0003704 specific RNA polymerase II transcription factor activity F 0 13 25 0 52 0 15 29 0 51.72414 -1.85 0 0 0008643 carbohydrate transport P 0 8 18 0 44.44444 0 15 43 0 34.88372 -1.85 0 0 0015464 acetylcholine receptor activity F 0 10 12 0 83.33334 0 15 19 0 78.94736 -1.85 0 0 0042166 acetylcholine binding F 0 0 0 0 0 0 15 19 0 78.94736 -1.85 0 0 0005328 neurotransmitter\:sodium symporter activity F 0 8 18 0 44.44444 0 15 28 0 53.57143 -1.85 0 0 0007345 embryogenesis and morphogenesis P 8 77 117 10.38961 65.81197 8 77 117 10.38961 65.81197 -1.853 0 0 0004553 hydrolase activity\, hydrolyzing O-glycosyl compounds F 0 12 37 0 32.43243 3 41 116 7.317073 35.34483 -1.856 0 0 0045892 negative regulation of transcription\, DNA-dependent P 0 0 2 0 0 3 41 70 7.317073 58.57143 -1.856 0 0 0008238 exopeptidase activity F 1 1 1 100 100 5 56 120 8.928572 46.66667 -1.86 0 0 0004674 protein serine/threonine kinase activity F 25 193 461 12.95337 41.86551 33 237 535 13.92405 44.29906 -1.865 0 0 0006936 muscle contraction P 4 51 72 7.843137 70.83334 10 91 141 10.98901 64.53901 -1.868 0 0 0016563 transcriptional activator activity F 1 25 61 4 40.98361 1 25 62 4 40.32258 -1.875 0 0 0015674 di-\, tri-valent inorganic cation transport P 0 0 0 0 0 6 64 104 9.375 61.53846 -1.897 0 0 0019955 cytokine binding F 1 1 1 100 100 3 42 61 7.142857 68.85246 -1.908 0 0 0001558 regulation of cell growth P 3 36 58 8.333333 62.06897 3 42 66 7.142857 63.63636 -1.908 0 0 0004497 monooxygenase activity F 3 25 72 12 34.72222 3 42 103 7.142857 40.7767 -1.908 0 0 0003811 complement activity F 0 12 13 0 92.30769 0 16 22 0 72.72727 -1.911 0 0 0005891 voltage-gated calcium channel complex C 0 16 25 0 64 0 16 25 0 64 -1.911 0 0 0004175 endopeptidase activity F 13 18 24 72.22222 75 20 158 352 12.65823 44.88636 -1.928 0 0 0006366 transcription from Pol II promoter P 21 133 182 15.78947 73.07692 45 314 424 14.33121 74.0566 -1.969 0 0 0001637 G-protein chemoattractant receptor activity F 0 0 0 0 0 0 17 28 0 60.71429 -1.97 0 0 0005581 collagen C 0 9 19 0 47.36842 0 17 37 0 45.94595 -1.97 0 0 0019956 chemokine binding F 0 0 0 0 0 0 17 28 0 60.71429 -1.97 0 0 0040007 growth P 0 14 20 0 70 0 17 25 0 68 -1.97 0 0 0005178 integrin binding F 0 17 23 0 73.91304 0 17 23 0 73.91304 -1.97 0 0 0004950 chemokine receptor activity F 0 3 6 0 50 0 17 28 0 60.71429 -1.97 0 0 0019842 vitamin binding F 0 0 0 0 0 0 17 28 0 60.71429 -1.97 0 0 0007498 mesoderm development P 0 14 20 0 70 0 17 27 0 62.96296 -1.97 0 0 0042379 chemokine receptor binding F 0 0 0 0 0 1 27 47 3.703704 57.44681 -1.989 0 0 0001664 G-protein-coupled receptor binding F 0 0 0 0 0 1 27 47 3.703704 57.44681 -1.989 0 0 0008009 chemokine activity F 1 27 47 3.703704 57.44681 1 27 47 3.703704 57.44681 -1.989 0 0 0008066 glutamate receptor activity F 0 0 0 0 0 0 18 57 0 31.57895 -2.027 0 0 0003795 antimicrobial peptide activity F 0 3 6 0 50 0 18 38 0 47.36842 -2.027 0 0 0004868 serpin F 0 18 18 0 100 0 18 18 0 100 -2.027 0 0 0005351 sugar porter activity F 0 18 44 0 40.90909 0 18 44 0 40.90909 -2.027 0 0 0042056 chemoattractant activity F 0 1 3 0 33.33333 1 28 50 3.571429 56 -2.043 0 0 0007586 digestion P 1 27 54 3.703704 50 1 28 60 3.571429 46.66667 -2.043 0 0 0007157 heterophilic cell adhesion P 4 55 98 7.272727 56.12245 5 60 105 8.333333 57.14286 -2.045 0 0 0008015 circulation P 3 30 50 10 60 5 60 99 8.333333 60.60606 -2.045 0 0 0015276 ligand-gated ion channel activity F 0 2 3 0 66.66666 5 60 111 8.333333 54.05405 -2.045 0 0 0003707 steroid hormone receptor activity F 2 33 59 6.060606 55.93221 2 37 65 5.405406 56.92308 -2.063 0 0 0007242 intracellular signaling cascade P 25 205 434 12.19512 47.23502 72 481 919 14.96881 52.3395 -2.095 0 0 0008146 sulfotransferase activity F 1 16 30 6.25 53.33333 1 29 47 3.448276 61.70213 -2.097 0 0 0007218 neuropeptide signaling pathway P 3 46 145 6.521739 31.72414 3 46 145 6.521739 31.72414 -2.106 0 0 0005083 small GTPase regulatory/interacting protein activity F 1 11 21 9.090909 52.38095 7 76 154 9.210526 49.35065 -2.106 0 0 0009888 histogenesis P 0 0 0 0 0 5 62 99 8.064516 62.62626 -2.134 0 0 0015144 carbohydrate transporter activity F 0 0 0 0 0 0 20 50 0 40 -2.137 0 0 0007243 protein kinase cascade P 2 22 28 9.090909 78.57143 9 91 130 9.89011 70 -2.14 0 0 0015293 symporter activity F 3 40 59 7.5 67.79661 4 55 91 7.272727 60.43956 -2.16 0 0 0019199 transmembrane receptor protein kinase activity F 0 0 0 0 0 4 55 95 7.272727 57.89474 -2.16 0 0 0004690 cyclic-nucleotide dependent protein kinase activity F 0 0 0 0 0 8 85 133 9.411765 63.90977 -2.181 0 0 0004691 cAMP-dependent protein kinase activity F 6 79 118 7.594937 66.94915 8 85 133 9.411765 63.90977 -2.181 0 0 0042165 neurotransmitter binding F 0 0 0 0 0 1 31 59 3.225806 52.54237 -2.2 0 0 0005262 calcium channel activity F 0 10 15 0 66.66666 1 31 52 3.225806 59.61538 -2.2 0 0 0016782 transferase activity\, transferring sulfur-containing groups F 0 0 0 0 0 1 31 52 3.225806 59.61538 -2.2 0 0 0030594 neurotransmitter receptor activity F 1 14 27 7.142857 51.85185 1 31 59 3.225806 52.54237 -2.2 0 0 0004879 ligand-dependent nuclear receptor activity F 0 1 4 0 25 2 40 71 5 56.33803 -2.211 0 0 0006816 calcium ion transport P 2 40 69 5 57.97102 2 40 69 5 57.97102 -2.211 0 0 0001568 blood vessel development P 0 0 0 0 0 0 22 28 0 78.57143 -2.242 0 0 0001525 angiogenesis P 0 21 27 0 77.77778 0 22 28 0 78.57143 -2.242 0 0 0004907 interleukin receptor activity F 0 3 4 0 75 0 22 30 0 73.33334 -2.242 0 0 0005529 sugar binding F 6 72 170 8.333333 42.35294 6 72 170 8.333333 42.35294 -2.242 0 0 0030246 carbohydrate binding F 0 0 0 0 0 6 72 173 8.333333 41.6185 -2.242 0 0 0006468 protein amino acid phosphorylation P 40 294 698 13.60544 42.12034 41 302 712 13.57616 42.41573 -2.274 0 0 0005488 binding F 4 41 111 9.756098 36.93694 645 3677 8619 17.54147 42.66156 -2.29 0 0 0006357 regulation of transcription from Pol II promoter P 16 121 157 13.22314 77.07006 19 163 214 11.65644 76.16822 -2.292 0 0 0019965 interleukin binding F 0 0 0 0 0 0 23 31 0 74.19355 -2.293 0 0 0016773 phosphotransferase activity\, alcohol group as acceptor F 2 4 5 50 80 54 383 871 14.09922 43.97245 -2.306 0 0 0007596 blood coagulation P 4 54 73 7.407407 73.9726 4 59 81 6.779661 72.83951 -2.336 0 0 0007204 cytosolic calcium ion concentration elevation P 0 24 36 0 66.66666 0 24 36 0 66.66666 -2.342 0 0 0019935 cyclic-nucleotide-mediated signaling P 0 0 0 0 0 5 67 95 7.462687 70.52631 -2.346 0 0 0007187 G-protein signaling\, coupled to cyclic nucleotide second messenger P 0 22 37 0 59.45946 5 67 95 7.462687 70.52631 -2.346 0 0 0006869 lipid transport P 1 30 50 3.333333 60 1 34 56 2.941176 60.71429 -2.347 0 0 0016042 lipid catabolism P 2 31 55 6.451613 56.36364 2 43 74 4.651163 58.10811 -2.352 0 0 0005625 soluble fraction C 15 139 195 10.79137 71.28205 15 139 195 10.79137 71.28205 -2.377 0 0 0007397 histogenesis and organogenesis P 3 52 80 5.769231 65 3 52 80 5.769231 65 -2.38 0 0 0003702 RNA polymerase II transcription factor activity F 9 96 126 9.375 76.19048 16 147 204 10.88435 72.05882 -2.417 0 0 0007610 behavior P 0 10 16 0 62.5 3 53 83 5.660378 63.85542 -2.423 0 0 0042277 peptide binding F 0 0 0 0 0 7 85 157 8.235294 54.14013 -2.462 0 0 0007599 hemostasis P 0 3 7 0 42.85714 4 62 88 6.451613 70.45454 -2.462 0 0 0019730 antimicrobial humoral response P 0 0 0 0 0 5 70 94 7.142857 74.46809 -2.468 0 0 0016065 humoral defense mechanism (sensu Invertebrata) P 0 0 0 0 0 5 70 93 7.142857 75.26881 -2.468 0 0 0006960 antimicrobial humoral response (sensu Invertebrata) P 5 67 90 7.462687 74.44444 5 70 93 7.142857 75.26881 -2.468 0 0 0030097 hemopoiesis P 0 5 10 0 50 0 27 45 0 60 -2.485 0 0 0005231 excitatory extracellular ligand-gated ion channel activity F 0 0 0 0 0 0 27 54 0 50 -2.485 0 0 0005509 calcium ion binding F 41 314 796 13.05732 39.44724 42 317 805 13.24921 39.37888 -2.486 0 0 0004222 metalloendopeptidase activity F 3 33 81 9.090909 40.74074 3 55 114 5.454545 48.24561 -2.509 0 0 0004682 protein kinase CK2 activity F 6 78 116 7.692307 67.24138 6 79 117 7.594937 67.52137 -2.52 0 0 0008233 peptidase activity F 3 29 126 10.34483 23.01587 39 300 728 13 41.20879 -2.529 0 0 0005179 hormone activity F 1 33 84 3.030303 39.28571 2 47 111 4.255319 42.34234 -2.53 0 0 0005230 extracellular ligand-gated ion channel activity F 1 26 47 3.846154 55.31915 1 38 76 2.631579 50 -2.531 0 0 0019932 second-messenger-mediated signaling P 0 0 0 0 0 5 72 101 6.944445 71.28713 -2.547 0 0 0004680 casein kinase activity F 0 0 0 0 0 6 80 121 7.5 66.1157 -2.558 0 0 0008150 biological_process P 0 0 0 0 0 1111 6136 14261 18.10626 43.02644 -2.571 0 0 0008076 voltage-gated potassium channel complex C 1 39 83 2.564103 46.98795 1 39 83 2.564103 46.98795 -2.576 0 0 0016788 hydrolase activity\, acting on ester bonds F 0 3 7 0 42.85714 37 291 698 12.71478 41.69054 -2.617 0 0 0042330 taxis P 0 0 0 0 0 4 67 109 5.970149 61.46789 -2.662 0 0 0006935 chemotaxis P 4 65 105 6.153846 61.90476 4 67 109 5.970149 61.46789 -2.662 0 0 0019838 growth factor binding F 0 1 2 0 50 0 31 46 0 67.3913 -2.663 0 0 0005244 voltage-gated ion channel activity F 2 21 31 9.523809 67.74194 7 91 187 7.692307 48.6631 -2.682 0 0 0003793 defense/immunity protein activity F 1 21 58 4.761905 36.2069 7 91 318 7.692307 28.61635 -2.682 0 0 0042221 response to chemical substance P 0 0 0 0 0 9 106 201 8.490566 52.73632 -2.685 0 0 0008227 amine receptor activity F 0 0 0 0 0 0 32 49 0 65.30612 -2.706 0 0 0046872 metal ion binding F 8 11 47 72.72727 23.40425 96 657 1566 14.61187 41.95402 -2.73 0 0 0004866 endopeptidase inhibitor activity F 0 8 14 0 57.14286 4 69 151 5.797101 45.69537 -2.739 0 0 0030414 protease inhibitor activity F 0 0 1 0 0 4 69 152 5.797101 45.39474 -2.739 0 0 0005085 guanyl-nucleotide exchange factor activity F 1 30 71 3.333333 42.25352 1 43 98 2.325581 43.87755 -2.746 0 0 0005201 extracellular matrix structural constituent F 1 41 93 2.439024 44.08602 1 44 112 2.272727 39.28571 -2.787 0 0 0007156 homophilic cell adhesion P 2 54 178 3.703704 30.33708 2 54 178 3.703704 30.33708 -2.818 0 0 0004672 protein kinase activity F 6 19 77 31.57895 24.67533 41 325 758 12.61539 42.87599 -2.82 0 0 0046914 transition metal ion binding F 0 0 0 0 0 33 274 617 12.0438 44.40843 -2.827 0 0 0003677 DNA binding F 73 444 1134 16.44144 39.15344 148 969 2234 15.27348 43.37511 -2.829 0 0 0004867 serine protease inhibitor activity F 1 45 102 2.222222 44.11765 1 46 104 2.173913 44.23077 -2.867 0 0 0005249 voltage-gated potassium channel activity F 0 23 77 0 29.87013 1 46 108 2.173913 42.59259 -2.867 0 0 0008237 metallopeptidase activity F 3 32 73 9.375 43.83562 8 104 243 7.692307 42.79836 -2.87 0 0 0001501 skeletal development P 4 57 91 7.017544 62.63736 4 73 124 5.479452 58.87097 -2.888 0 0 0015291 porter activity F 0 0 0 0 0 9 115 277 7.826087 41.51625 -2.984 0 0 0015290 electrochemical potential-driven transporter activity F 0 0 0 0 0 9 115 277 7.826087 41.51625 -2.984 0 0 0004713 protein-tyrosine kinase activity F 13 127 301 10.23622 42.19269 17 173 377 9.82659 45.8886 -2.99 0 0 0007200 G-protein signaling\, coupled to IP3 second messenger (phospholipase C activating) P 0 6 12 0 50 1 50 79 2 63.29114 -3.022 0 0 0009987 cellular process P 0 0 0 0 0 569 3336 7238 17.05635 46.09008 -3.074 0 0 0006959 humoral immune response P 2 20 28 10 71.42857 9 118 157 7.627119 75.15923 -3.079 0 0 0005125 cytokine activity F 4 44 82 9.090909 53.65854 9 119 218 7.563025 54.58715 -3.11 0 0 0009314 response to radiation P 2 4 4 50 100 9 120 205 7.5 58.53659 -3.142 0 0 0004252 serine-type endopeptidase activity F 1 7 16 14.28571 43.75 4 81 186 4.938272 43.54839 -3.17 0 0 0006813 potassium ion transport P 4 82 180 4.878049 45.55556 4 82 180 4.878049 45.55556 -3.204 0 0 0005057 receptor signaling protein activity F 2 29 44 6.896552 65.90909 9 123 184 7.317073 66.84782 -3.234 0 0 0005267 potassium channel activity F 2 27 49 7.407407 55.10204 2 66 155 3.030303 42.58065 -3.259 0 0 0004263 chymotrypsin activity F 1 57 119 1.754386 47.89916 1 57 119 1.754386 47.89916 -3.276 0 0 0008270 zinc ion binding F 20 205 499 9.756098 41.08216 20 205 499 9.756098 41.08216 -3.288 0 0 0003674 molecular_function F 0 0 0 0 0 1158 6402 16003 18.0881 40.005 -3.292 0 0 0030001 metal ion transport P 2 11 25 18.18182 44 16 177 365 9.039548 48.49315 -3.298 0 0 0004295 trypsin activity F 1 57 134 1.754386 42.53731 1 58 137 1.724138 42.33577 -3.31 0 0 0008236 serine-type peptidase activity F 0 2 7 0 28.57143 4 87 203 4.597701 42.85714 -3.369 0 0 0007601 vision P 6 104 181 5.769231 57.45856 6 105 183 5.714286 57.37705 -3.41 0 0 0008083 growth factor activity F 4 73 136 5.479452 53.67647 5 98 171 5.102041 57.30994 -3.449 0 0 0009583 perception of light P 0 0 0 0 0 6 107 192 5.607477 55.72917 -3.471 0 0 0009582 perception of abiotic stimulus P 0 2 4 0 50 13 163 589 7.97546 27.67402 -3.515 0 0 0009416 response to light P 0 1 1 0 100 6 110 195 5.454545 56.41026 -3.562 0 0 0008528 peptide receptor activity\, G-protein coupled F 0 2 4 0 50 1 67 122 1.492537 54.91803 -3.609 0 0 0001653 peptide receptor activity F 0 0 0 0 0 1 67 122 1.492537 54.91803 -3.609 0 0 0007600 sensory perception P 0 10 21 0 47.61905 13 169 597 7.692307 28.30821 -3.676 0 0 0016337 cell-cell adhesion P 1 15 29 6.666667 51.72414 8 131 313 6.10687 41.85303 -3.699 0 0 0045087 innate immune response P 0 1 3 0 33.33333 7 124 185 5.645161 67.02702 -3.73 0 0 0016020 membrane C 58 364 1248 15.93407 29.16667 336 2114 4998 15.89404 42.29692 -3.764 0 0 0005216 ion channel activity F 1 66 130 1.515152 50.76923 16 197 420 8.121827 46.90476 -3.82 0 0 0005578 extracellular matrix C 5 96 178 5.208333 53.93258 10 154 286 6.493506 53.84615 -3.893 0 0 0006954 inflammatory response P 6 118 170 5.084746 69.41177 6 122 176 4.918033 69.31818 -3.908 0 0 0019226 transmission of nerve impulse P 0 1 1 0 100 11 163 257 6.748466 63.42413 -3.923 0 0 0007399 neurogenesis P 11 149 223 7.38255 66.81615 21 239 363 8.786611 65.84022 -3.952 0 0 0009581 perception of external stimulus P 0 0 0 0 0 13 180 624 7.222222 28.84615 -3.962 0 0 0030154 cell differentiation P 1 44 78 2.272727 56.41026 2 89 152 2.247191 58.55263 -3.982 0 0 0007268 synaptic transmission P 4 126 202 3.174603 62.37624 10 161 255 6.21118 63.13726 -4.075 0 0 0005194 cell adhesion molecule activity F 10 164 327 6.097561 50.1529 16 208 407 7.692307 51.10565 -4.09 0 0 0015267 channel/pore class transporter activity F 1 5 9 20 55.55556 17 218 468 7.798165 46.5812 -4.15 0 0 0006350 transcription P 13 47 98 27.65957 47.95918 122 903 2072 13.51052 43.58108 -4.176 0 0 0015268 alpha-type channel activity F 0 0 0 0 0 16 212 451 7.54717 47.00665 -4.186 0 0 0006351 transcription\, DNA-dependent P 1 4 6 25 66.66666 118 881 2018 13.39387 43.65709 -4.213 0 0 0009611 response to wounding P 0 7 12 0 58.33333 10 167 257 5.988024 64.98055 -4.227 0 0 0005261 cation channel activity F 3 17 64 17.64706 26.5625 6 138 306 4.347826 45.09804 -4.335 0 0 0009613 response to pest/pathogen/parasite P 0 4 13 0 30.76923 24 280 432 8.571428 64.81481 -4.385 0 0 0009628 response to abiotic stimulus P 0 1 1 0 100 24 284 810 8.450705 35.06173 -4.471 0 0 0005615 extracellular space C 13 212 305 6.132075 69.50819 13 216 309 6.018518 69.90292 -4.813 0 0 0003700 transcription factor activity F 44 444 992 9.90991 44.75806 45 455 1008 9.89011 45.13889 -4.916 0 0 0007186 G-protein coupled receptor protein signaling pathway P 17 189 947 8.994709 19.95776 26 321 1245 8.099689 25.78313 -4.932 0 0 0030528 transcription regulator activity F 0 5 12 0 41.66667 71 631 1242 11.25198 50.80515 -4.946 0 0 0005102 receptor binding F 5 43 69 11.62791 62.31884 20 282 552 7.092198 51.08696 -5.053 0 0 0016021 integral to membrane C 152 924 2379 16.45022 38.83985 234 1638 3498 14.28571 46.82676 -5.076 0 0 0001584 rhodopsin-like receptor activity F 3 131 337 2.290076 38.8724 5 164 880 3.04878 18.63636 -5.168 0 0 0007155 cell adhesion P 15 226 466 6.637168 48.49785 27 345 702 7.826087 49.1453 -5.256 0 0 0045449 regulation of transcription P 0 2 4 0 50 98 829 1938 11.82147 42.77606 -5.31 0 0 0006355 regulation of transcription\, DNA-dependent P 75 685 1727 10.9489 39.66416 97 823 1924 11.78615 42.77547 -5.316 0 0 0004930 G-protein coupled receptor activity F 4 39 132 10.25641 29.54545 9 213 1040 4.225352 20.48077 -5.463 0 0 0009607 response to biotic stimulus P 1 2 2 50 100 47 512 1044 9.179688 49.04214 -5.667 0 0 0007166 cell surface receptor linked signal transduction P 7 83 133 8.433735 62.40601 49 536 1594 9.141791 33.6261 -5.832 0 0 0006955 immune response P 16 229 574 6.986899 39.89547 35 436 889 8.027523 49.04387 -5.838 0 0 0007267 cell-cell signaling P 11 187 288 5.882353 64.93056 22 346 542 6.358381 63.83764 -5.985 0 0 0009653 morphogenesis P 0 1 3 0 33.33333 46 527 804 8.728653 65.54726 -6.033 0 0 0009887 organogenesis P 0 0 1 0 0 42 503 769 8.3499 65.40962 -6.11 0 0 0006952 defense response P 3 34 73 8.823529 46.57534 36 466 953 7.725322 48.89822 -6.223 0 0 0009605 response to external stimulus P 0 5 6 0 83.33334 70 749 1783 9.345795 42.00785 -6.859 0 0 0005886 plasma membrane C 33 178 260 18.53933 68.46154 108 1006 1577 10.73559 63.79201 -6.893 0 0 0007165 signal transduction P 62 547 954 11.33455 57.33752 156 1334 3088 11.69415 43.19948 -7.163 0 0 0004872 receptor activity F 44 344 1085 12.7907 31.70507 64 734 2183 8.719346 33.62346 -7.244 0 0 0004888 transmembrane receptor activity F 5 71 119 7.042253 59.66386 32 500 1597 6.4 31.3087 -7.254 0 0 0007275 development P 23 284 503 8.098592 56.46123 85 916 1531 9.279476 59.83018 -7.744 0 0 0005887 integral to plasma membrane C 53 648 965 8.179012 67.15026 61 749 1159 8.144193 64.62468 -7.755 0 0 0005576 extracellular C 9 182 552 4.945055 32.97102 30 519 1108 5.780347 46.84116 -7.779 0 0 0004871 signal transducer activity F 20 134 277 14.92537 48.37545 106 1188 3058 8.922559 38.84892 -9.371 0 0 0007154 cell communication P 1 11 27 9.090909 40.74074 185 1708 3830 10.83138 44.5953 -9.442 0 0