Cluster n°1 Index Path GOID GO Name GO Type Number Changed Local Number Measured Local Number in GO Local Percent Changed Local Percent Present Local Number Changed Number Measured Number in GO Percent Changed Percent Present Z Score PermuteP AdjustedP 1 0.0.2.0 7154 cell communication P 0 11 27 0 40.7 91 1708 3830 5.3 44.6 2.774 2 0.0.2.0.7 7165 signal transduction P 33 547 954 6 57.3 71 1334 3088 5.3 43.2 2.358 3 0.0.2.0.7.0.3.5.0.1 7193 "G-protein signaling\, adenylate cyclase inhibiting pathway" P 0 5 7 0 71.4 3 19 24 15.8 79.2 2.541 4 0.0.2.0.7.0.3.5.0.1.3 45761 regulation of adenylate cyclase activity P 0 0 0 0 0 3 11 14 27.3 78.6 3.84 5 0.0.2.0.7.0.3.5.0.1.3.0 7194 negative regulation of adenylate cyclase activity P 3 11 14 27.3 78.6 3 11 14 27.3 78.6 3.84 6 0.0.2.0.7.2.12.1.0.0.1 7193 "G-protein signaling\, adenylate cyclase inhibiting pathway" P 0 5 7 0 71.4 3 19 24 15.8 79.2 2.541 7 0.0.2.0.7.2.12.1.0.0.1.3 45761 regulation of adenylate cyclase activity P 0 0 0 0 0 3 11 14 27.3 78.6 3.84 8 0.0.2.0.7.2.12.1.0.0.1.3.0 7194 negative regulation of adenylate cyclase activity P 3 11 14 27.3 78.6 3 11 14 27.3 78.6 3.84 9 0.0.2.0.7.2.12.1.2.0.1 7193 "G-protein signaling\, adenylate cyclase inhibiting pathway" P 0 5 7 0 71.4 3 19 24 15.8 79.2 2.541 10 0.0.2.0.7.2.12.1.2.0.1.3 45761 regulation of adenylate cyclase activity P 0 0 0 0 0 3 11 14 27.3 78.6 3.84 11 0.0.2.0.7.2.12.1.2.0.1.3.0 7194 negative regulation of adenylate cyclase activity P 3 11 14 27.3 78.6 3 11 14 27.3 78.6 3.84 12 0.0.2.3.2.8 1558 regulation of cell growth P 4 36 58 11.1 62.1 5 42 66 11.9 63.6 2.52 13 0.0.2.3.10.16 46907 intracellular transport P 0 0 0 0 0 3 294 508 1 57.9 -2.756 14 0.0.2.3.10.16.8 6886 intracellular protein transport P 2 173 294 1.2 58.8 3 242 386 1.2 62.7 -2.317 15 0.0.2.3.10.22 6836 neurotransmitter transport P 4 18 36 22.2 50 4 23 42 17.4 54.8 3.181 16 0.0.2.3.10.32 15031 protein transport P 1 18 36 5.6 50 4 258 421 1.6 61.3 -2.14 17 0.0.2.3.10.32.2 6886 intracellular protein transport P 2 173 294 1.2 58.8 3 242 386 1.2 62.7 -2.317 18 0.0.3 7275 development P 18 284 503 6.3 56.5 50 916 1531 5.5 59.8 2.107 19 0.0.3.12 9653 morphogenesis P 0 1 3 0 33.3 35 527 804 6.6 65.5 2.963 20 0.0.3.12.8 9887 organogenesis P 0 0 1 0 0 34 503 769 6.8 65.4 3.027 21 0.0.3.12.8.1 1568 blood vessel development P 0 0 0 0 0 5 22 28 22.7 78.6 4.366 22 0.0.3.12.8.1.0 1525 angiogenesis P 5 21 27 23.8 77.8 5 22 28 22.7 78.6 4.366 23 0.0.3.12.8.19 7399 neurogenesis P 9 149 223 6 66.8 18 239 363 7.5 65.8 2.653 24 0.0.3.12.8.19.2 7417 central nervous system development P 5 41 63 12.2 65.1 7 60 92 11.7 65.2 2.923 25 0.0.4.90 7345 embryogenesis and morphogenesis P 8 77 117 10.4 65.8 8 77 117 10.4 65.8 2.751 26 0.0.5 7582 physiological processes P 1 10 18 10 55.6 200 5176 11583 3.9 44.7 -2.11 27 0.0.5.3.2.8 1558 regulation of cell growth P 4 36 58 11.1 62.1 5 42 66 11.9 63.6 2.52 28 0.0.5.3.10.16 46907 intracellular transport P 0 0 0 0 0 3 294 508 1 57.9 -2.756 29 0.0.5.3.10.16.8 6886 intracellular protein transport P 2 173 294 1.2 58.8 3 242 386 1.2 62.7 -2.317 30 0.0.5.3.10.22 6836 neurotransmitter transport P 4 18 36 22.2 50 4 23 42 17.4 54.8 3.181 31 0.0.5.3.10.32 15031 protein transport P 1 18 36 5.6 50 4 258 421 1.6 61.3 -2.14 32 0.0.5.3.10.32.2 6886 intracellular protein transport P 2 173 294 1.2 58.8 3 242 386 1.2 62.7 -2.317 33 0.0.5.9 7586 digestion P 4 27 54 14.8 50 4 28 60 14.3 46.7 2.687 34 0.0.5.20.0.16.0 8203 cholesterol metabolism P 2 20 31 10 64.5 4 35 52 11.4 67.3 2.157 35 0.0.5.20.20.13.11.0 8203 cholesterol metabolism P 2 20 31 10 64.5 4 35 52 11.4 67.3 2.157 36 0.0.5.20.33.0.0 16311 dephosphorylation P 0 1 1 0 100 8 80 169 10 47.3 2.629 37 0.0.5.20.33.0.0.2 6470 protein amino acid dephosphorylation P 8 79 168 10.1 47 8 79 168 10.1 47 2.669 38 0.0.5.20.35.14.23 6470 protein amino acid dephosphorylation P 8 79 168 10.1 47 8 79 168 10.1 47 2.669 39 0.0.5.31 7565 pregnancy P 2 19 47 10.5 40.4 3 23 52 13 44.2 2.136 40 0.1.0.7 5622 intracellular C 8 235 665 3.4 35.3 116 3212 6357 3.6 50.5 -2.127 41 0.1.2 5576 extracellular C 16 182 552 8.8 33 36 519 1108 6.9 46.8 3.288 42 0.1.2.2 5615 extracellular space C 14 212 305 6.6 69.5 15 216 309 6.9 69.9 2.079 43 0.2.4.22.1 3723 RNA binding F 5 254 450 2 56.4 5 315 560 1.6 56.2 -2.342 44 0.2.5.20.10.5 42578 phosphoric ester hydrolase activity F 1 2 3 50 66.7 13 165 366 7.9 45.1 2.419 45 0.2.5.20.10.5.2.52.2 8138 protein tyrosine/serine/threonine phosphatase activity F 1 14 38 7.1 36.8 3 20 53 15 37.7 2.43 46 0.2.5.20.13.5.5 4252 serine-type endopeptidase activity F 0 7 16 0 43.8 7 81 186 8.6 43.5 2.03 47 0.2.5.20.13.6.1 4180 carboxypeptidase activity F 3 15 25 20 60 3 24 56 12.5 42.9 2.048 48 0.2.5.20.13.10.2 4252 serine-type endopeptidase activity F 0 7 16 0 43.8 7 81 186 8.6 43.5 2.03 49 0.2.23 4871 signal transducer activity F 9 134 277 6.7 48.4 63 1188 3058 5.3 38.8 2.16 50 0.2.29.1 5275 amine/polyamine transporter activity F 0 0 0 0 0 5 50 89 10 56.2 2.074 51 0.2.29.1.1.7 15179 L-amino acid transporter activity F 0 0 0 0 0 3 13 18 23.1 72.2 3.417 52 0.2.29.5.0.1.37.10 15294 solute\:cation symporter activity F 0 1 1 0 100 4 28 47 14.3 59.6 2.687 53 0.2.29.5.0.1.37.10.9 15370 solute\:sodium symporter activity F 0 0 0 0 0 4 21 39 19 53.8 3.42 54 0.2.29.5.0.1.37.10.9.7 5328 neurotransmitter\:sodium symporter activity F 1 8 18 12.5 44.4 4 15 28 26.7 53.6 4.368 55 0.2.29.6.0.1.2.3 5262 calcium channel activity F 1 10 15 10 66.7 4 31 52 12.9 59.6 2.442 56 0.2.29.6.0.1.2.3.3 5245 voltage-gated calcium channel activity F 3 13 24 23.1 54.2 3 19 31 15.8 61.3 2.541 57 0.2.29.6.0.1.7.0 5245 voltage-gated calcium channel activity F 3 13 24 23.1 54.2 3 19 31 15.8 61.3 2.541 58 0.2.29.14 5326 neurotransmitter transporter activity F 0 0 1 0 0 4 16 30 25 53.3 4.178 59 0.2.29.14.1 5328 neurotransmitter\:sodium symporter activity F 1 8 18 12.5 44.4 4 15 28 26.7 53.6 4.368 60 0.2.29.17.0.0.7 15179 L-amino acid transporter activity F 0 0 0 0 0 3 13 18 23.1 72.2 3.417 Cluster n°2 Index Path GOID GO Name GO Type Number Changed Local Number Measured Local Number in GO Local Percent Changed Local Percent Present Local Number Changed Number Measured Number in GO Percent Changed Percent Present Z Score PermuteP AdjustedP 1 0.0.5.20.25.0 6259 DNA metabolism P 0 16 23 0 69.6 5 280 614 1.8 45.6 2.023 2 0.0.5.20.25.10 16070 RNA metabolism P 0 2 3 0 66.7 4 175 297 2.3 58.9 2.359 3 0.1 5575 cellular_component C 0 0 0 0 0 49 5407 12138 0.9 44.5 2.638 4 0.1.0.7.7.16 5783 endoplasmic reticulum C 4 166 260 2.4 63.8 5 232 362 2.2 64.1 2.495 5 0.1.0.7.21.18 5654 nucleoplasm C 2 27 39 7.4 69.2 3 128 204 2.3 62.7 2.087 6 0.2.4.19 46872 metal ion binding F 0 11 47 0 23.4 10 657 1566 1.5 42 2.372 7 0.2.4.19.0 5509 calcium ion binding F 5 314 796 1.6 39.4 7 317 805 2.2 39.4 3.046 8 0.2.5.20.10.5.2.52 4721 protein phosphatase activity F 0 10 23 0 43.5 3 99 201 3 49.3 2.625 9 0.2.5.33 16491 oxidoreductase activity F 6 250 472 2.4 53 7 359 748 1.9 48 2.673 Cluster n°3 Index Path GOID GO Name GO Type Number Changed Local Number Measured Local Number in GO Local Percent Changed Local Percent Present Local Number Changed Number Measured Number in GO Percent Changed Percent Present Z Score PermuteP AdjustedP 1 0 8150 biological_process P 0 0 0 0 0 126 6136 14261 2.1 43 -3.113 2 0.0.2 9987 cellular process P 0 0 0 0 0 59 3336 7238 1.8 46.1 -2.641 3 0.0.2.0 7154 cell communication P 0 11 27 0 40.7 22 1708 3830 1.3 44.6 -3.109 4 0.0.2.0.7 7165 signal transduction P 11 547 954 2 57.3 19 1334 3088 1.4 43.2 -2.283 5 0.0.2.3.4.5 7028 cytoplasm organization and biogenesis P 0 0 0 0 0 9 193 369 4.7 52.3 2.278 6 0.0.2.3.4.5.2 6996 organelle organization and biogenesis P 1 2 3 50 66.7 8 170 325 4.7 52.3 2.172 7 0.0.2.3.5.0 7049 cell cycle P 2 77 156 2.6 49.4 16 392 716 4.1 54.7 2.497 8 0.0.2.3.5.0.1 67 DNA replication and chromosome cycle P 1 5 6 20 83.3 9 112 225 8 49.8 4.146 9 0.0.2.3.5.0.1.3 6260 DNA replication P 3 50 94 6 53.2 6 83 186 7.2 44.6 3.064 10 0.0.2.3.5.0.4 278 mitotic cell cycle P 0 0 0 0 0 11 196 354 5.6 55.4 3.203 11 0.0.2.3.5.0.4.1 82 G1/S transition of mitotic cell cycle P 2 8 14 25 57.1 3 36 53 8.3 67.9 2.458 12 0.0.2.3.5.0.4.8 84 S phase of mitotic cell cycle P 0 1 2 0 50 6 83 187 7.2 44.4 3.064 13 0.0.2.3.5.0.4.8.0 6260 DNA replication P 3 50 94 6 53.2 6 83 186 7.2 44.6 3.064 14 0.0.2.3.10.16 46907 intracellular transport P 0 0 0 0 0 14 294 508 4.8 57.9 2.949 15 0.0.2.3.10.16.8 6886 intracellular protein transport P 10 173 294 5.8 58.8 12 242 386 5 62.7 2.875 16 0.0.2.3.10.32 15031 protein transport P 1 18 36 5.6 50 13 258 421 5 61.3 3.06 17 0.0.2.3.10.32.2 6886 intracellular protein transport P 10 173 294 5.8 58.8 12 242 386 5 62.7 2.875 18 0.0.3 7275 development P 3 284 503 1.1 56.5 7 916 1531 0.8 59.8 -3.267 19 0.0.4.133 6371 mRNA splicing P 4 32 46 12.5 69.6 4 32 46 12.5 69.6 3.906 20 0.0.5.3.4.5 7028 cytoplasm organization and biogenesis P 0 0 0 0 0 9 193 369 4.7 52.3 2.278 21 0.0.5.3.4.5.2 6996 organelle organization and biogenesis P 1 2 3 50 66.7 8 170 325 4.7 52.3 2.172 22 0.0.5.3.5.0 7049 cell cycle P 2 77 156 2.6 49.4 16 392 716 4.1 54.7 2.497 23 0.0.5.3.5.0.1 67 DNA replication and chromosome cycle P 1 5 6 20 83.3 9 112 225 8 49.8 4.146 24 0.0.5.3.5.0.1.3 6260 DNA replication P 3 50 94 6 53.2 6 83 186 7.2 44.6 3.064 25 0.0.5.3.5.0.4 278 mitotic cell cycle P 0 0 0 0 0 11 196 354 5.6 55.4 3.203 26 0.0.5.3.5.0.4.1 82 G1/S transition of mitotic cell cycle P 2 8 14 25 57.1 3 36 53 8.3 67.9 2.458 27 0.0.5.3.5.0.4.8 84 S phase of mitotic cell cycle P 0 1 2 0 50 6 83 187 7.2 44.4 3.064 28 0.0.5.3.5.0.4.8.0 6260 DNA replication P 3 50 94 6 53.2 6 83 186 7.2 44.6 3.064 29 0.0.5.3.10.16 46907 intracellular transport P 0 0 0 0 0 14 294 508 4.8 57.9 2.949 30 0.0.5.3.10.16.8 6886 intracellular protein transport P 10 173 294 5.8 58.8 12 242 386 5 62.7 2.875 31 0.0.5.3.10.32 15031 protein transport P 1 18 36 5.6 50 13 258 421 5 61.3 3.06 32 0.0.5.3.10.32.2 6886 intracellular protein transport P 10 173 294 5.8 58.8 12 242 386 5 62.7 2.875 33 0.0.5.20.5.22.3.19 6445 regulation of translation P 3 12 21 25 57.1 4 41 66 9.8 62.1 3.239 34 0.0.5.20.5.22.3.29 6413 translational initiation P 2 17 31 11.8 54.8 3 40 64 7.5 62.5 2.236 35 0.0.5.20.11 6118 electron transport P 7 187 511 3.7 36.6 9 201 545 4.5 36.9 2.146 36 0.0.5.20.25.0 6259 DNA metabolism P 2 16 23 12.5 69.6 14 280 614 5 45.6 3.148 37 0.0.5.20.25.0.8 6260 DNA replication P 3 50 94 6 53.2 6 83 186 7.2 44.6 3.064 38 0.0.5.20.25.10 16070 RNA metabolism P 0 2 3 0 66.7 11 175 297 6.3 58.9 3.629 39 0.0.5.20.25.10.3 6396 RNA processing P 3 37 67 8.1 55.2 10 159 273 6.3 58.2 3.458 40 0.0.5.20.25.10.3.0.5 398 "nuclear mRNA splicing\, via spliceosome" P 5 49 71 10.2 69 5 60 86 8.3 69.8 3.179 41 0.0.5.20.25.10.3.3 8380 RNA splicing P 1 7 13 14.3 53.8 6 65 97 9.2 67 3.799 42 0.0.5.20.25.10.3.3.1 375 "RNA splicing\, via transesterification reactions" P 0 0 0 0 0 5 60 86 8.3 69.8 3.179 43 0.0.5.20.25.10.3.3.1.0 377 "RNA splicing\, via transesterification reactions with bulged adenosine as nucleophile" P 0 0 0 0 0 5 60 86 8.3 69.8 3.179 44 0.0.5.20.25.10.3.3.1.0.2 398 "nuclear mRNA splicing\, via spliceosome" P 5 49 71 10.2 69 5 60 86 8.3 69.8 3.179 45 0.0.5.20.25.11.0 45449 regulation of transcription P 0 2 4 0 50 9 829 1938 1.1 42.8 -2.423 46 0.0.5.20.25.11.0.2 6355 "regulation of transcription\, DNA-dependent" P 5 685 1727 0.7 39.7 9 823 1924 1.1 42.8 -2.397 47 0.0.5.20.25.11.1.2 6355 "regulation of transcription\, DNA-dependent" P 5 685 1727 0.7 39.7 9 823 1924 1.1 42.8 -2.397 48 0.0.5.20.35.9.19 6445 regulation of translation P 3 12 21 25 57.1 4 41 66 9.8 62.1 3.239 49 0.0.5.20.35.9.29 6413 translational initiation P 2 17 31 11.8 54.8 3 40 64 7.5 62.5 2.236 50 0.0.5.20.35.14.61 6512 ubiquitin cycle P 5 47 114 10.6 41.2 5 52 128 9.6 40.6 3.582 51 0.0.5.34 9605 response to external stimulus P 0 5 6 0 83.3 7 749 1783 0.9 42 -2.583 52 0.0.5.34.3 9607 response to biotic stimulus P 0 2 2 0 100 5 512 1044 1 49 -2.03 53 0.1 5575 cellular_component C 0 0 0 0 0 107 5407 12138 2 44.5 -2.922 54 0.1.0.7 5622 intracellular C 4 235 665 1.7 35.3 85 3212 6357 2.6 50.5 2.003 55 0.1.0.7.7.16 5783 endoplasmic reticulum C 8 166 260 4.8 63.8 12 232 362 5.2 64.1 3.035 56 0.1.0.7.7.38 5739 mitochondrion C 13 296 445 4.4 66.5 13 335 541 3.9 61.9 2.045 57 0.1.0.7.7.38.4 5759 mitochondrial matrix C 0 19 29 0 65.5 4 42 64 9.5 65.6 3.177 58 0.1.0.7.7.38.4.7 5761 mitochondrial ribosome C 1 6 7 16.7 85.7 3 16 26 18.8 61.5 4.443 59 0.1.0.7.7.54.3 313 organellar ribosome C 0 0 0 0 0 3 16 26 18.8 61.5 4.443 60 0.1.0.7.7.54.3.0 5761 mitochondrial ribosome C 1 6 7 16.7 85.7 3 16 26 18.8 61.5 4.443 61 0.1.0.7.21.15 5635 nuclear membrane C 1 14 22 7.1 63.6 4 48 72 8.3 66.7 2.841 62 0.1.0.7.21.15.4 5643 nuclear pore C 3 28 43 10.7 65.1 3 28 43 10.7 65.1 3.016 63 0.1.0.7.21.27 30532 small nuclear ribonucleoprotein complex C 2 8 12 25 66.7 4 14 19 28.6 73.7 6.63 64 0.1.0.7.21.28 5681 spliceosome complex C 2 22 40 9.1 55 4 27 46 14.8 58.7 4.397 65 0.1.0.7.32 30529 ribonucleoprotein complex C 5 29 46 17.2 63 14 181 334 7.7 54.2 5.021 66 0.1.0.7.32.5.3 313 organellar ribosome C 0 0 0 0 0 3 16 26 18.8 61.5 4.443 67 0.1.0.7.32.5.3.0 5761 mitochondrial ribosome C 1 6 7 16.7 85.7 3 16 26 18.8 61.5 4.443 68 0.1.0.7.32.7 30532 small nuclear ribonucleoprotein complex C 2 8 12 25 66.7 4 14 19 28.6 73.7 6.63 69 0.1.0.7.32.9 5681 spliceosome complex C 2 22 40 9.1 55 4 27 46 14.8 58.7 4.397 70 0.1.0.8 16020 membrane C 9 364 1248 2.5 29.2 28 2114 4998 1.3 42.3 -3.465 71 0.1.0.8.1.3 5635 nuclear membrane C 1 14 22 7.1 63.6 4 48 72 8.3 66.7 2.841 72 0.1.0.8.1.3.4 5643 nuclear pore C 3 28 43 10.7 65.1 3 28 43 10.7 65.1 3.016 73 0.1.0.8.7 16021 integral to membrane C 5 924 2379 0.5 38.8 13 1638 3498 0.8 46.8 -4.563 74 0.1.0.8.7.4 5887 integral to plasma membrane C 5 648 965 0.8 67.2 5 749 1159 0.7 64.6 -3.103 75 0.1.0.8.7.9 46930 pore complex C 0 0 0 0 0 3 28 42 10.7 66.7 3.016 76 0.1.0.8.7.9.1 5643 nuclear pore C 3 28 43 10.7 65.1 3 28 43 10.7 65.1 3.016 77 0.1.0.8.13 5886 plasma membrane C 3 178 260 1.7 68.5 11 1006 1577 1.1 63.8 -2.691 78 0.1.0.8.13.19 5887 integral to plasma membrane C 5 648 965 0.8 67.2 5 749 1159 0.7 64.6 -3.103 79 0.1.2 5576 extracellular C 1 182 552 0.5 33 4 519 1108 0.8 46.8 -2.372 80 0.1.4.0 5837 26S proteasome C 3 30 35 10 85.7 3 30 35 10 85.7 2.858 81 0.2.4.22.1 3723 RNA binding F 15 254 450 5.9 56.4 18 315 560 5.7 56.2 4.221 82 0.2.4.22.1.5 3729 mRNA binding F 0 9 11 0 81.8 6 70 95 8.6 73.7 3.571 83 0.2.4.22.1.5.5 8248 pre-mRNA splicing factor activity F 6 50 71 12 70.4 6 50 71 12 70.4 4.65 84 0.2.4.22.2 8135 "translation factor activity\, nucleic acid binding" F 0 4 5 0 80 5 68 112 7.4 60.7 2.839 85 0.2.4.22.2.7 3743 translation initiation factor activity F 4 43 71 9.3 60.6 4 43 71 9.3 60.6 3.116 86 0.2.5.20.1 16817 "hydrolase activity\, acting on acid anhydrides" F 0 0 0 0 0 14 315 688 4.4 45.8 2.669 87 0.2.5.20.1.1 16818 "hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides" F 0 0 0 0 0 13 298 653 4.4 45.6 2.495 88 0.2.5.20.1.1.20 3924 GTPase activity F 0 16 36 0 44.4 7 135 287 5.2 47 2.309 89 0.2.5.20.1.1.20.4 3925 small monomeric GTPase activity F 0 26 71 0 36.6 5 89 196 5.6 45.4 2.145 90 0.2.5.20.1.1.20.4.1 3928 RAB small monomeric GTPase activity F 4 36 74 11.1 48.6 4 36 74 11.1 48.6 3.582 91 0.2.5.22 16853 isomerase activity F 3 57 96 5.3 59.4 4 66 122 6.1 54.1 2.087 92 0.2.5.24.3.1 16881 acid-D-amino acid ligase activity F 0 0 0 0 0 4 53 139 7.5 38.1 2.599 93 0.2.5.24.3.1.22 4842 ubiquitin-protein ligase activity F 4 46 116 8.7 39.7 4 46 116 8.7 39.7 2.946 94 0.2.5.33 16491 oxidoreductase activity F 10 250 472 4 53 15 359 748 4.2 48 2.511 95 0.2.5.33.15 15036 disulfide oxidoreductase activity F 0 12 21 0 57.1 3 23 34 13 67.6 3.485 96 0.2.5.33.32 16651 "oxidoreductase activity\, acting on NADH or NADPH" F 0 0 0 0 0 4 42 77 9.5 54.5 3.177 97 0.2.5.33.32.5 16659 "oxidoreductase activity\, acting on NADH or NADPH\, other acceptor" F 0 0 0 0 0 3 28 38 10.7 73.7 3.016 98 0.2.5.33.32.5.3 3954 NADH dehydrogenase activity F 3 26 36 11.5 72.2 3 26 36 11.5 72.2 3.189 99 0.2.5.33.32.6 16655 "oxidoreductase activity\, acting on NADH or NADPH\, quinone or similar compound as acceptor" F 0 0 0 0 0 3 29 57 10.3 50.9 2.935 100 0.2.5.33.32.6.3 8137 NADH dehydrogenase (ubiquinone) activity F 3 26 54 11.5 48.1 3 26 54 11.5 48.1 3.189 101 0.2.5.33.42 16903 "oxidoreductase activity\, acting on the aldehyde or oxo group of donors" F 0 0 0 0 0 3 19 31 15.8 61.3 3.973 102 0.2.5.43 8639 small protein conjugating enzyme activity F 0 0 1 0 0 4 40 73 10 54.8 3.303 103 0.2.5.43.1 4840 ubiquitin conjugating enzyme activity F 4 39 71 10.3 54.9 4 39 71 10.3 54.9 3.369 104 0.2.5.47.15 16741 "transferase activity\, transferring one-carbon groups" F 0 0 0 0 0 5 69 159 7.2 43.4 2.8 105 0.2.5.47.15.2 8168 methyltransferase activity F 2 23 44 8.7 52.3 5 66 154 7.6 42.9 2.919 106 0.2.5.47.15.2.18 8757 S-adenosylmethionine-dependent methyltransferase activity F 1 18 45 5.6 40 3 43 85 7 50.6 2.087 107 0.2.23 4871 signal transducer activity F 4 134 277 3 48.4 11 1188 3058 0.9 38.8 -3.396 108 0.2.23.5 4872 receptor activity F 3 344 1085 0.9 31.7 3 734 2183 0.4 33.6 -3.567 109 0.2.27 30528 transcription regulator activity F 0 5 12 0 41.7 7 631 1242 1.1 50.8 -2.039 110 0.2.28 45182 translation regulator activity F 0 1 1 0 100 5 70 114 7.1 61.4 2.762 111 0.2.28.1 8135 "translation factor activity\, nucleic acid binding" F 0 4 5 0 80 5 68 112 7.4 60.7 2.839 112 0.2.28.1.7 3743 translation initiation factor activity F 4 43 71 9.3 60.6 4 43 71 9.3 60.6 3.116 113 0.2.29.5.3.5 8137 NADH dehydrogenase (ubiquinone) activity F 3 26 54 11.5 48.1 3 26 54 11.5 48.1 3.189 114 0.2.29.8 5489 electron transporter activity F 8 138 331 5.8 41.7 12 175 382 6.9 45.8 4.144 115 0.2.29.8.17 3954 NADH dehydrogenase activity F 3 26 36 11.5 72.2 3 26 36 11.5 72.2 3.189 116 0.2.29.11.1.4.0.8 8137 NADH dehydrogenase (ubiquinone) activity F 3 26 54 11.5 48.1 3 26 54 11.5 48.1 3.189 117 0.2.29.11.1.4.3 15081 sodium ion transporter activity F 0 2 2 0 100 3 29 57 10.3 50.9 2.935 118 0.2.29.11.1.4.3.0 8137 NADH dehydrogenase (ubiquinone) activity F 3 26 54 11.5 48.1 3 26 54 11.5 48.1 3.189 119 0.2.29.11.2 46873 metal ion transporter activity F 1 8 19 12.5 42.1 4 61 104 6.6 58.7 2.268 120 0.2.29.11.2.7 15081 sodium ion transporter activity F 0 2 2 0 100 3 29 57 10.3 50.9 2.935 121 0.2.29.11.2.7.0 8137 NADH dehydrogenase (ubiquinone) activity F 3 26 54 11.5 48.1 3 26 54 11.5 48.1 3.189 122 0.2.29.25 8565 protein transporter activity F 11 165 264 6.7 62.5 12 180 285 6.7 63.2 4.03 Cluster n°4 Index Path GOID GO Name GO Type Number Changed Local Number Measured Local Number in GO Local Percent Changed Local Percent Present Local Number Changed Number Measured Number in GO Percent Changed Percent Present Z Score PermuteP AdjustedP 1 0.0.2 9987 cellular process P 0 0 0 0 0 126 3336 7238 3.8 46.1 2.112 2 0.0.2.0.0 7155 cell adhesion P 13 226 466 5.8 48.5 22 345 702 6.4 49.1 3.274 3 0.0.2.0.0.3 7160 cell-matrix adhesion P 4 41 83 9.8 49.4 4 41 84 9.8 48.8 2.318 4 0.0.2.0.7.0.4 7229 integrin-mediated signaling pathway P 3 26 39 11.5 66.7 3 26 39 11.5 66.7 2.353 5 0.0.2.3.10.17.3.1 30001 metal ion transport P 0 11 25 0 44 11 177 365 6.2 48.5 2.194 6 0.0.2.3.10.17.3.1.4 6813 potassium ion transport P 8 82 180 9.8 45.6 8 82 180 9.8 45.6 3.288 7 0.0.2.3.10.17.3.2.0 6813 potassium ion transport P 8 82 180 9.8 45.6 8 82 180 9.8 45.6 3.288 8 0.0.3 7275 development P 20 284 503 7 56.5 49 916 1531 5.3 59.8 3.714 9 0.0.3.12 9653 morphogenesis P 0 1 3 0 33.3 27 527 804 5.1 65.5 2.429 10 0.0.3.12.8 9887 organogenesis P 0 0 1 0 0 27 503 769 5.4 65.4 2.687 11 0.0.3.12.8.13 9888 histogenesis P 0 0 0 0 0 5 62 99 8.1 62.6 2.106 12 0.0.3.12.8.13.0 7398 ectoderm development P 1 4 9 25 44.4 4 43 70 9.3 61.4 2.207 13 0.0.3.12.8.23 1501 skeletal development P 4 57 91 7 62.6 6 73 124 8.2 58.9 2.361 14 0.0.5.3.10.17.3.1 30001 metal ion transport P 0 11 25 0 44 11 177 365 6.2 48.5 2.194 15 0.0.5.3.10.17.3.1.4 6813 potassium ion transport P 8 82 180 9.8 45.6 8 82 180 9.8 45.6 3.288 16 0.0.5.3.10.17.3.2.0 6813 potassium ion transport P 8 82 180 9.8 45.6 8 82 180 9.8 45.6 3.288 17 0.0.5.15 7599 hemostasis P 0 3 7 0 42.9 5 62 88 8.1 70.5 2.106 18 0.0.5.15.0 7596 blood coagulation P 5 54 73 9.3 74 5 59 81 8.5 72.8 2.231 19 0.0.5.20 8152 metabolism P 11 185 456 5.9 40.6 100 3523 7651 2.8 46 -2.196 20 0.0.5.20.5 9058 biosynthesis P 2 24 66 8.3 36.4 9 603 1112 1.5 54.2 -2.604 21 0.0.5.20.5.22 9059 macromolecule biosynthesis P 0 0 0 0 0 4 316 597 1.3 52.9 -2.074 22 0.0.5.20.5.22.3 6412 protein biosynthesis P 0 132 243 0 54.3 4 316 597 1.3 52.9 -2.074 23 0.0.5.20.20 6629 lipid metabolism P 1 77 129 1.3 59.7 4 318 519 1.3 61.3 -2.089 24 0.0.5.20.25.11.0 45449 regulation of transcription P 0 2 4 0 50 39 829 1938 4.7 42.8 2.402 25 0.0.5.20.25.11.0.2 6355 "regulation of transcription\, DNA-dependent" P 32 685 1727 4.7 39.7 39 823 1924 4.7 42.8 2.451 26 0.0.5.20.25.11.0.2.5 6357 regulation of transcription from Pol II promoter P 9 121 157 7.4 77.1 11 163 214 6.7 76.2 2.489 27 0.0.5.20.25.11.1.2 6355 "regulation of transcription\, DNA-dependent" P 32 685 1727 4.7 39.7 39 823 1924 4.7 42.8 2.451 28 0.0.5.20.25.11.1.2.5 6357 regulation of transcription from Pol II promoter P 9 121 157 7.4 77.1 11 163 214 6.7 76.2 2.489 29 0.0.5.20.25.11.1.10 6366 transcription from Pol II promoter P 7 133 182 5.3 73.1 18 314 424 5.7 74.1 2.463 30 0.0.5.20.25.11.1.10.2 6357 regulation of transcription from Pol II promoter P 9 121 157 7.4 77.1 11 163 214 6.7 76.2 2.489 31 0.0.5.20.35 19538 protein metabolism P 0 10 15 0 66.7 30 1343 2803 2.2 47.9 -2.441 32 0.0.5.20.35.9 6412 protein biosynthesis P 0 132 243 0 54.3 4 316 597 1.3 52.9 -2.074 33 0.1.0.7.7 5737 cytoplasm C 8 377 601 2.1 62.7 41 1758 2986 2.3 58.9 -2.635 34 0.1.0.8.7.4 5887 integral to plasma membrane C 28 648 965 4.3 67.2 34 749 1159 4.5 64.6 2.001 35 0.1.0.8.7.4.7 8305 integrin complex C 3 22 47 13.6 46.8 3 22 47 13.6 46.8 2.715 36 0.1.0.8.13 5886 plasma membrane C 7 178 260 3.9 68.5 44 1006 1577 4.4 63.8 2.051 37 0.1.0.8.13.2 16327 apicolateral plasma membrane C 0 0 0 0 0 5 43 94 11.6 45.7 3.063 38 0.1.0.8.13.2.1 5911 intercellular junction C 2 11 19 18.2 57.9 5 40 90 12.5 44.4 3.263 39 0.1.0.8.13.8 30054 cell junction C 0 0 1 0 0 5 45 97 11.1 46.4 2.939 40 0.1.0.8.13.8.2 5911 intercellular junction C 2 11 19 18.2 57.9 5 40 90 12.5 44.4 3.263 41 0.1.0.8.13.19 5887 integral to plasma membrane C 28 648 965 4.3 67.2 34 749 1159 4.5 64.6 2.001 42 0.1.0.8.13.19.7 8305 integrin complex C 3 22 47 13.6 46.8 3 22 47 13.6 46.8 2.715 43 0.2.4.22.0.23 3700 transcription factor activity F 22 444 992 5 44.8 26 455 1008 5.7 45.1 2.974 44 0.2.4.22.0.23.0 3705 "RNA polymerase II transcription factor activity\, enhancer binding" F 4 11 16 36.4 68.8 4 11 16 36.4 68.8 6.138 45 0.2.4.22.1 3723 RNA binding F 3 254 450 1.2 56.4 3 315 560 1 56.2 -2.39 46 0.2.4.30.58.0.0 3713 transcription co-activator activity F 7 90 119 7.8 75.6 7 92 131 7.6 70.2 2.325 47 0.2.5 3824 catalytic activity F 3 69 225 4.3 30.7 66 2470 5598 2.7 44.1 -2.186 48 0.2.6 5194 cell adhesion molecule activity F 12 164 327 7.3 50.2 16 208 407 7.7 51.1 3.594 49 0.2.6.4 4895 cell adhesion receptor activity F 4 32 62 12.5 51.6 4 32 62 12.5 51.6 2.917 50 0.2.23.5.16.3 4895 cell adhesion receptor activity F 4 32 62 12.5 51.6 4 32 62 12.5 51.6 2.917 51 0.2.27 30528 transcription regulator activity F 0 5 12 0 41.7 32 631 1242 5.1 50.8 2.603 52 0.2.27.2 3702 RNA polymerase II transcription factor activity F 5 96 126 5.2 76.2 10 147 204 6.8 72.1 2.398 53 0.2.27.2.3 3705 "RNA polymerase II transcription factor activity\, enhancer binding" F 4 11 16 36.4 68.8 4 11 16 36.4 68.8 6.138 54 0.2.27.5.0 3713 transcription co-activator activity F 7 90 119 7.8 75.6 7 92 131 7.6 70.2 2.325 55 0.2.27.6 3700 transcription factor activity F 22 444 992 5 44.8 26 455 1008 5.7 45.1 2.974 56 0.2.27.6.0 3705 "RNA polymerase II transcription factor activity\, enhancer binding" F 4 11 16 36.4 68.8 4 11 16 36.4 68.8 6.138 57 0.2.29.6.0.1.2.9 5267 potassium channel activity F 3 27 49 11.1 55.1 8 66 155 12.1 42.6 4.026 58 0.2.29.6.0.1.2.9.2 5249 voltage-gated potassium channel activity F 3 23 77 13 29.9 4 46 108 8.7 42.6 2.052 59 0.2.29.6.0.1.7.2 5249 voltage-gated potassium channel activity F 3 23 77 13 29.9 4 46 108 8.7 42.6 2.052 Cluster n°5 NA Cluster n°6 Index Path GOID GO Name GO Type Number Changed Local Number Measured Local Number in GO Local Percent Changed Local Percent Present Local Number Changed Number Measured Number in GO Percent Changed Percent Present Z Score PermuteP AdjustedP 1 0.0.1 4 biological_process unknown P 9 336 838 2.7 40.1 9 336 838 2.7 40.1 -2.005 2 0.0.2.0 7154 cell communication P 1 11 27 9.1 40.7 44 1708 3830 2.6 44.6 -5.298 3 0.0.2.0.0 7155 cell adhesion P 3 226 466 1.3 48.5 7 345 702 2 49.1 -2.601 4 0.0.2.0.2 7267 cell-cell signaling P 0 187 288 0 64.9 4 346 542 1.2 63.8 -3.368 5 0.0.2.0.7 7165 signal transduction P 15 547 954 2.7 57.3 36 1334 3088 2.7 43.2 -4.296 6 0.0.2.0.7.0 7166 cell surface receptor linked signal transduction P 1 83 133 1.2 62.4 8 536 1594 1.5 33.6 -3.882 7 0.0.2.0.7.0.3 7186 G-protein coupled receptor protein signaling pathway P 0 189 947 0 20 3 321 1245 0.9 25.8 -3.425 8 0.0.2.3 8151 cell growth and/or maintenance P 5 133 249 3.8 53.4 118 1909 3822 6.2 49.9 2.76 9 0.0.2.3.4 16043 cell organization and biogenesis P 0 0 0 0 0 30 306 631 9.8 48.5 3.935 10 0.0.2.3.4.5 7028 cytoplasm organization and biogenesis P 0 0 0 0 0 18 193 369 9.3 52.3 2.791 11 0.0.2.3.4.5.2 6996 organelle organization and biogenesis P 0 2 3 0 66.7 15 170 325 8.8 52.3 2.31 12 0.0.2.3.4.5.2.0 7010 cytoskeleton organization and biogenesis P 2 19 44 10.5 43.2 11 112 243 9.8 46.1 2.355 13 0.0.2.3.4.5.3 42254 ribosome biogenesis and assembly P 0 0 0 0 0 3 20 37 15 54.1 2.052 14 0.0.2.3.4.5.3.1 7046 ribosome biogenesis P 1 4 8 25 50 3 20 37 15 54.1 2.052 15 0.0.2.3.4.8 6997 nuclear organization and biogenesis P 0 2 3 0 66.7 12 86 226 14 38.1 3.828 16 0.0.2.3.4.8.0 7001 chromosome organization and biogenesis (sensu Eukarya) P 3 20 76 15 26.3 12 84 224 14.3 37.5 3.923 17 0.0.2.3.4.8.0.0 6325 establishment and/or maintenance of chromatin architecture P 0 6 16 0 37.5 8 63 192 12.7 32.8 2.812 18 0.0.2.3.4.8.0.0.1 16568 chromatin modification P 2 18 40 11.1 45 5 35 73 14.3 47.9 2.523 19 0.0.2.3.4.8.0.0.1.1 16582 non-covalent chromatin modification P 0 0 0 0 0 3 15 34 20 44.1 2.665 20 0.0.2.3.4.8.0.0.1.1.0 6338 chromatin modeling P 3 13 17 23.1 76.5 3 15 34 20 44.1 2.665 21 0.0.2.3.5.0 7049 cell cycle P 11 77 156 14.3 49.4 34 392 716 8.7 54.7 3.426 22 0.0.2.3.5.0.1 67 DNA replication and chromosome cycle P 0 5 6 0 83.3 15 112 225 13.4 49.8 4.103 23 0.0.2.3.5.0.1.2 7059 chromosome segregation P 2 9 13 22.2 69.2 3 15 21 20 71.4 2.665 24 0.0.2.3.5.0.1.3 6260 DNA replication P 8 50 94 16 53.2 11 83 186 13.3 44.6 3.465 25 0.0.2.3.5.0.3 279 M phase P 0 1 3 0 33.3 11 100 150 11 66.7 2.768 26 0.0.2.3.5.0.3.0 87 M phase of mitotic cell cycle P 0 2 3 0 66.7 10 78 114 12.8 68.4 3.182 27 0.0.2.3.5.0.3.0.1 7067 mitosis P 9 55 78 16.4 70.5 10 76 111 13.2 68.5 3.276 28 0.0.2.3.5.0.3.0.1.9 7088 regulation of mitosis P 0 5 8 0 62.5 3 17 25 17.6 68 2.393 29 0.0.2.3.5.0.3.0.1.9.0 7093 mitotic checkpoint P 2 7 8 28.6 87.5 3 9 13 33.3 69.2 3.899 30 0.0.2.3.5.0.3.2 280 nuclear division P 0 0 0 0 0 11 96 141 11.5 68.1 2.919 31 0.0.2.3.5.0.3.2.1 7067 mitosis P 9 55 78 16.4 70.5 10 76 111 13.2 68.5 3.276 32 0.0.2.3.5.0.3.2.1.9 7088 regulation of mitosis P 0 5 8 0 62.5 3 17 25 17.6 68 2.393 33 0.0.2.3.5.0.3.2.1.9.0 7093 mitotic checkpoint P 2 7 8 28.6 87.5 3 9 13 33.3 69.2 3.899 34 0.0.2.3.5.0.4 278 mitotic cell cycle P 0 0 0 0 0 24 196 354 12.2 55.4 4.713 35 0.0.2.3.5.0.4.4 87 M phase of mitotic cell cycle P 0 2 3 0 66.7 10 78 114 12.8 68.4 3.182 36 0.0.2.3.5.0.4.4.1 7067 mitosis P 9 55 78 16.4 70.5 10 76 111 13.2 68.5 3.276 37 0.0.2.3.5.0.4.4.1.9 7088 regulation of mitosis P 0 5 8 0 62.5 3 17 25 17.6 68 2.393 38 0.0.2.3.5.0.4.4.1.9.0 7093 mitotic checkpoint P 2 7 8 28.6 87.5 3 9 13 33.3 69.2 3.899 39 0.0.2.3.5.0.4.8 84 S phase of mitotic cell cycle P 0 1 2 0 50 11 83 187 13.3 44.4 3.465 40 0.0.2.3.5.0.4.8.0 6260 DNA replication P 8 50 94 16 53.2 11 83 186 13.3 44.6 3.465 41 0.0.2.3.5.0.6 74 regulation of cell cycle P 8 107 179 7.5 59.8 18 224 357 8 62.7 2.113 42 0.0.2.3.5.0.6.1 75 cell cycle checkpoint P 1 7 11 14.3 63.6 5 24 34 20.8 70.6 3.561 43 0.0.2.3.5.0.6.1.3 7093 mitotic checkpoint P 2 7 8 28.6 87.5 3 9 13 33.3 69.2 3.899 44 0.0.2.3.5.0.6.7 7088 regulation of mitosis P 0 5 8 0 62.5 3 17 25 17.6 68 2.393 45 0.0.2.3.5.0.6.7.0 7093 mitotic checkpoint P 2 7 8 28.6 87.5 3 9 13 33.3 69.2 3.899 46 0.0.2.3.5.1 910 cytokinesis P 7 46 94 15.2 48.9 7 47 95 14.9 49.5 3.118 47 0.0.2.3.10.15 6818 hydrogen transport P 0 0 0 0 0 9 43 89 20.9 48.3 4.803 48 0.0.2.3.10.15.1 15992 proton transport P 8 39 82 20.5 47.6 9 42 88 21.4 47.7 4.895 49 0.0.2.3.10.16 46907 intracellular transport P 0 0 0 0 0 24 294 508 8.2 57.9 2.536 50 0.0.2.3.10.16.4.1 6888 ER to Golgi transport P 3 10 20 30 50 3 10 20 30 50 3.627 51 0.0.2.3.10.16.8 6886 intracellular protein transport P 17 173 294 9.8 58.8 21 242 386 8.7 62.7 2.665 52 0.0.2.3.10.17.1.1 15711 organic anion transport P 1 9 13 11.1 69.2 3 20 33 15 60.6 2.052 53 0.0.2.3.10.17.3.2 15672 monovalent inorganic cation transport P 0 0 0 0 0 13 150 332 8.7 45.2 2.078 54 0.0.2.3.10.17.3.2.1 15992 proton transport P 8 39 82 20.5 47.6 9 42 88 21.4 47.7 4.895 55 0.0.2.3.10.32 15031 protein transport P 0 18 36 0 50 21 258 421 8.1 61.3 2.351 56 0.0.2.3.10.32.2 6886 intracellular protein transport P 17 173 294 9.8 58.8 21 242 386 8.7 62.7 2.665 57 0.0.2.3.10.33.1 6888 ER to Golgi transport P 3 10 20 30 50 3 10 20 30 50 3.627 58 0.0.2.3.10.36.5.1 6888 ER to Golgi transport P 3 10 20 30 50 3 10 20 30 50 3.627 59 0.0.3 7275 development P 5 284 503 1.8 56.5 22 916 1531 2.4 59.8 -3.878 60 0.0.3.12 9653 morphogenesis P 0 1 3 0 33.3 14 527 804 2.7 65.5 -2.572 61 0.0.3.12.8 9887 organogenesis P 0 0 1 0 0 13 503 769 2.6 65.4 -2.585 62 0.0.4.133 6371 mRNA splicing P 5 32 46 15.6 69.6 5 32 46 15.6 69.6 2.761 63 0.0.5 7582 physiological processes P 0 10 18 0 55.6 280 5176 11583 5.4 44.7 2.61 64 0.0.5.3 8151 cell growth and/or maintenance P 5 133 249 3.8 53.4 118 1909 3822 6.2 49.9 2.76 65 0.0.5.3.4 16043 cell organization and biogenesis P 0 0 0 0 0 30 306 631 9.8 48.5 3.935 66 0.0.5.3.4.5 7028 cytoplasm organization and biogenesis P 0 0 0 0 0 18 193 369 9.3 52.3 2.791 67 0.0.5.3.4.5.2 6996 organelle organization and biogenesis P 0 2 3 0 66.7 15 170 325 8.8 52.3 2.31 68 0.0.5.3.4.5.2.0 7010 cytoskeleton organization and biogenesis P 2 19 44 10.5 43.2 11 112 243 9.8 46.1 2.355 69 0.0.5.3.4.5.3 42254 ribosome biogenesis and assembly P 0 0 0 0 0 3 20 37 15 54.1 2.052 70 0.0.5.3.4.5.3.1 7046 ribosome biogenesis P 1 4 8 25 50 3 20 37 15 54.1 2.052 71 0.0.5.3.4.8 6997 nuclear organization and biogenesis P 0 2 3 0 66.7 12 86 226 14 38.1 3.828 72 0.0.5.3.4.8.0 7001 chromosome organization and biogenesis (sensu Eukarya) P 3 20 76 15 26.3 12 84 224 14.3 37.5 3.923 73 0.0.5.3.4.8.0.0 6325 establishment and/or maintenance of chromatin architecture P 0 6 16 0 37.5 8 63 192 12.7 32.8 2.812 74 0.0.5.3.4.8.0.0.1 16568 chromatin modification P 2 18 40 11.1 45 5 35 73 14.3 47.9 2.523 75 0.0.5.3.4.8.0.0.1.1 16582 non-covalent chromatin modification P 0 0 0 0 0 3 15 34 20 44.1 2.665 76 0.0.5.3.4.8.0.0.1.1.0 6338 chromatin modeling P 3 13 17 23.1 76.5 3 15 34 20 44.1 2.665 77 0.0.5.3.5.0 7049 cell cycle P 11 77 156 14.3 49.4 34 392 716 8.7 54.7 3.426 78 0.0.5.3.5.0.1 67 DNA replication and chromosome cycle P 0 5 6 0 83.3 15 112 225 13.4 49.8 4.103 79 0.0.5.3.5.0.1.2 7059 chromosome segregation P 2 9 13 22.2 69.2 3 15 21 20 71.4 2.665 80 0.0.5.3.5.0.1.3 6260 DNA replication P 8 50 94 16 53.2 11 83 186 13.3 44.6 3.465 81 0.0.5.3.5.0.3 279 M phase P 0 1 3 0 33.3 11 100 150 11 66.7 2.768 82 0.0.5.3.5.0.3.0 87 M phase of mitotic cell cycle P 0 2 3 0 66.7 10 78 114 12.8 68.4 3.182 83 0.0.5.3.5.0.3.0.1 7067 mitosis P 9 55 78 16.4 70.5 10 76 111 13.2 68.5 3.276 84 0.0.5.3.5.0.3.0.1.9 7088 regulation of mitosis P 0 5 8 0 62.5 3 17 25 17.6 68 2.393 85 0.0.5.3.5.0.3.0.1.9.0 7093 mitotic checkpoint P 2 7 8 28.6 87.5 3 9 13 33.3 69.2 3.899 86 0.0.5.3.5.0.3.2 280 nuclear division P 0 0 0 0 0 11 96 141 11.5 68.1 2.919 87 0.0.5.3.5.0.3.2.1 7067 mitosis P 9 55 78 16.4 70.5 10 76 111 13.2 68.5 3.276 88 0.0.5.3.5.0.3.2.1.9 7088 regulation of mitosis P 0 5 8 0 62.5 3 17 25 17.6 68 2.393 89 0.0.5.3.5.0.3.2.1.9.0 7093 mitotic checkpoint P 2 7 8 28.6 87.5 3 9 13 33.3 69.2 3.899 90 0.0.5.3.5.0.4 278 mitotic cell cycle P 0 0 0 0 0 24 196 354 12.2 55.4 4.713 91 0.0.5.3.5.0.4.4 87 M phase of mitotic cell cycle P 0 2 3 0 66.7 10 78 114 12.8 68.4 3.182 92 0.0.5.3.5.0.4.4.1 7067 mitosis P 9 55 78 16.4 70.5 10 76 111 13.2 68.5 3.276 93 0.0.5.3.5.0.4.4.1.9 7088 regulation of mitosis P 0 5 8 0 62.5 3 17 25 17.6 68 2.393 94 0.0.5.3.5.0.4.4.1.9.0 7093 mitotic checkpoint P 2 7 8 28.6 87.5 3 9 13 33.3 69.2 3.899 95 0.0.5.3.5.0.4.8 84 S phase of mitotic cell cycle P 0 1 2 0 50 11 83 187 13.3 44.4 3.465 96 0.0.5.3.5.0.4.8.0 6260 DNA replication P 8 50 94 16 53.2 11 83 186 13.3 44.6 3.465 97 0.0.5.3.5.0.6 74 regulation of cell cycle P 8 107 179 7.5 59.8 18 224 357 8 62.7 2.113 98 0.0.5.3.5.0.6.1 75 cell cycle checkpoint P 1 7 11 14.3 63.6 5 24 34 20.8 70.6 3.561 99 0.0.5.3.5.0.6.1.3 7093 mitotic checkpoint P 2 7 8 28.6 87.5 3 9 13 33.3 69.2 3.899 100 0.0.5.3.5.0.6.7 7088 regulation of mitosis P 0 5 8 0 62.5 3 17 25 17.6 68 2.393 101 0.0.5.3.5.0.6.7.0 7093 mitotic checkpoint P 2 7 8 28.6 87.5 3 9 13 33.3 69.2 3.899 102 0.0.5.3.5.1 910 cytokinesis P 7 46 94 15.2 48.9 7 47 95 14.9 49.5 3.118 103 0.0.5.3.10.15 6818 hydrogen transport P 0 0 0 0 0 9 43 89 20.9 48.3 4.803 104 0.0.5.3.10.15.1 15992 proton transport P 8 39 82 20.5 47.6 9 42 88 21.4 47.7 4.895 105 0.0.5.3.10.16 46907 intracellular transport P 0 0 0 0 0 24 294 508 8.2 57.9 2.536 106 0.0.5.3.10.16.4.1 6888 ER to Golgi transport P 3 10 20 30 50 3 10 20 30 50 3.627 107 0.0.5.3.10.16.8 6886 intracellular protein transport P 17 173 294 9.8 58.8 21 242 386 8.7 62.7 2.665 108 0.0.5.3.10.17.1.1 15711 organic anion transport P 1 9 13 11.1 69.2 3 20 33 15 60.6 2.052 109 0.0.5.3.10.17.3.2 15672 monovalent inorganic cation transport P 0 0 0 0 0 13 150 332 8.7 45.2 2.078 110 0.0.5.3.10.17.3.2.1 15992 proton transport P 8 39 82 20.5 47.6 9 42 88 21.4 47.7 4.895 111 0.0.5.3.10.32 15031 protein transport P 0 18 36 0 50 21 258 421 8.1 61.3 2.351 112 0.0.5.3.10.32.2 6886 intracellular protein transport P 17 173 294 9.8 58.8 21 242 386 8.7 62.7 2.665 113 0.0.5.3.10.33.1 6888 ER to Golgi transport P 3 10 20 30 50 3 10 20 30 50 3.627 114 0.0.5.3.10.36.5.1 6888 ER to Golgi transport P 3 10 20 30 50 3 10 20 30 50 3.627 115 0.0.5.20.0.3 46164 alcohol catabolism P 0 0 0 0 0 5 37 69 13.5 53.6 2.379 116 0.0.5.20.0.3.8 46365 monosaccharide catabolism P 0 0 0 0 0 5 37 69 13.5 53.6 2.379 117 0.0.5.20.0.3.8.0 19320 hexose catabolism P 0 0 0 0 0 5 36 68 13.9 52.9 2.45 118 0.0.5.20.0.3.8.0.4 6007 glucose catabolism P 0 2 2 0 100 5 35 67 14.3 52.2 2.523 119 0.0.5.20.0.3.8.0.4.0 6096 glycolysis P 4 29 55 13.8 52.7 4 29 55 13.8 52.7 2.174 120 0.0.5.20.0.11.0.4.3 6007 glucose catabolism P 0 2 2 0 100 5 35 67 14.3 52.2 2.523 121 0.0.5.20.0.11.0.4.3.0 6096 glycolysis P 4 29 55 13.8 52.7 4 29 55 13.8 52.7 2.174 122 0.0.5.20.0.11.0.6 19320 hexose catabolism P 0 0 0 0 0 5 36 68 13.9 52.9 2.45 123 0.0.5.20.0.11.0.6.4 6007 glucose catabolism P 0 2 2 0 100 5 35 67 14.3 52.2 2.523 124 0.0.5.20.0.11.0.6.4.0 6096 glycolysis P 4 29 55 13.8 52.7 4 29 55 13.8 52.7 2.174 125 0.0.5.20.0.11.2 46365 monosaccharide catabolism P 0 0 0 0 0 5 37 69 13.5 53.6 2.379 126 0.0.5.20.0.11.2.0 19320 hexose catabolism P 0 0 0 0 0 5 36 68 13.9 52.9 2.45 127 0.0.5.20.0.11.2.0.4 6007 glucose catabolism P 0 2 2 0 100 5 35 67 14.3 52.2 2.523 128 0.0.5.20.0.11.2.0.4.0 6096 glycolysis P 4 29 55 13.8 52.7 4 29 55 13.8 52.7 2.174 129 0.0.5.20.5.12 46138 coenzymes and prosthetic group biosynthesis P 0 0 0 0 0 8 44 89 18.2 49.4 4.02 130 0.0.5.20.5.12.0 9108 coenzyme biosynthesis P 0 0 2 0 0 7 35 73 20 47.9 4.077 131 0.0.5.20.5.12.0.3 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 132 0.0.5.20.5.22.3.19 6445 regulation of translation P 1 12 21 8.3 57.1 5 41 66 12.2 62.1 2.117 133 0.0.5.20.5.22.3.19.7 6446 regulation of translational initiation P 4 22 33 18.2 66.7 4 23 34 17.4 67.6 2.728 134 0.0.5.20.5.22.3.26 6414 translational elongation P 3 20 37 15 54.1 3 20 39 15 51.3 2.052 135 0.0.5.20.5.22.3.29.3 6446 regulation of translational initiation P 4 22 33 18.2 66.7 4 23 34 17.4 67.6 2.728 136 0.0.5.20.5.27 9165 nucleotide biosynthesis P 2 6 12 33.3 50 10 54 102 18.5 52.9 4.57 137 0.0.5.20.5.27.4 9142 nucleoside triphosphate biosynthesis P 0 2 3 0 66.7 5 26 44 19.2 59.1 3.332 138 0.0.5.20.5.27.4.1 9145 purine nucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 139 0.0.5.20.5.27.4.1.1 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 140 0.0.5.20.5.27.4.1.1.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 141 0.0.5.20.5.27.4.3 9201 ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 142 0.0.5.20.5.27.4.3.0 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 143 0.0.5.20.5.27.4.3.0.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 144 0.0.5.20.5.27.5 6164 purine nucleotide biosynthesis P 2 3 10 66.7 30 8 34 61 23.5 55.7 4.964 145 0.0.5.20.5.27.5.3 9145 purine nucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 146 0.0.5.20.5.27.5.3.1 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 147 0.0.5.20.5.27.5.3.1.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 148 0.0.5.20.5.27.5.4 9152 purine ribonucleotide biosynthesis P 1 1 1 100 100 6 31 57 19.4 54.4 3.671 149 0.0.5.20.5.27.5.4.2 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 150 0.0.5.20.5.27.5.4.2.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 151 0.0.5.20.5.27.8 9260 ribonucleotide biosynthesis P 0 0 0 0 0 6 35 63 17.1 55.6 3.3 152 0.0.5.20.5.27.8.0 9152 purine ribonucleotide biosynthesis P 1 1 1 100 100 6 31 57 19.4 54.4 3.671 153 0.0.5.20.5.27.8.0.2 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 154 0.0.5.20.5.27.8.0.2.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 155 0.0.5.20.5.27.8.4 9201 ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 156 0.0.5.20.5.27.8.4.0 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 157 0.0.5.20.5.27.8.4.0.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 158 0.0.5.20.6.6.7 46365 monosaccharide catabolism P 0 0 0 0 0 5 37 69 13.5 53.6 2.379 159 0.0.5.20.6.6.7.0 19320 hexose catabolism P 0 0 0 0 0 5 36 68 13.9 52.9 2.45 160 0.0.5.20.6.6.7.0.4 6007 glucose catabolism P 0 2 2 0 100 5 35 67 14.3 52.2 2.523 161 0.0.5.20.6.6.7.0.4.0 6096 glycolysis P 4 29 55 13.8 52.7 4 29 55 13.8 52.7 2.174 162 0.0.5.20.6.12 6092 main pathways of carbohydrate metabolism P 0 0 2 0 0 8 58 108 13.8 53.7 3.081 163 0.0.5.20.6.12.2 6096 glycolysis P 4 29 55 13.8 52.7 4 29 55 13.8 52.7 2.174 164 0.0.5.20.6.12.6 6099 tricarboxylic acid cycle P 4 17 29 23.5 58.6 4 17 29 23.5 58.6 3.506 165 0.0.5.20.6.13.0.4.3 6007 glucose catabolism P 0 2 2 0 100 5 35 67 14.3 52.2 2.523 166 0.0.5.20.6.13.0.4.3.0 6096 glycolysis P 4 29 55 13.8 52.7 4 29 55 13.8 52.7 2.174 167 0.0.5.20.6.13.0.6 19320 hexose catabolism P 0 0 0 0 0 5 36 68 13.9 52.9 2.45 168 0.0.5.20.6.13.0.6.4 6007 glucose catabolism P 0 2 2 0 100 5 35 67 14.3 52.2 2.523 169 0.0.5.20.6.13.0.6.4.0 6096 glycolysis P 4 29 55 13.8 52.7 4 29 55 13.8 52.7 2.174 170 0.0.5.20.6.13.2 46365 monosaccharide catabolism P 0 0 0 0 0 5 37 69 13.5 53.6 2.379 171 0.0.5.20.6.13.2.0 19320 hexose catabolism P 0 0 0 0 0 5 36 68 13.9 52.9 2.45 172 0.0.5.20.6.13.2.0.4 6007 glucose catabolism P 0 2 2 0 100 5 35 67 14.3 52.2 2.523 173 0.0.5.20.6.13.2.0.4.0 6096 glycolysis P 4 29 55 13.8 52.7 4 29 55 13.8 52.7 2.174 174 0.0.5.20.8.0 46164 alcohol catabolism P 0 0 0 0 0 5 37 69 13.5 53.6 2.379 175 0.0.5.20.8.0.8 46365 monosaccharide catabolism P 0 0 0 0 0 5 37 69 13.5 53.6 2.379 176 0.0.5.20.8.0.8.0 19320 hexose catabolism P 0 0 0 0 0 5 36 68 13.9 52.9 2.45 177 0.0.5.20.8.0.8.0.4 6007 glucose catabolism P 0 2 2 0 100 5 35 67 14.3 52.2 2.523 178 0.0.5.20.8.0.8.0.4.0 6096 glycolysis P 4 29 55 13.8 52.7 4 29 55 13.8 52.7 2.174 179 0.0.5.20.8.8.7 46365 monosaccharide catabolism P 0 0 0 0 0 5 37 69 13.5 53.6 2.379 180 0.0.5.20.8.8.7.0 19320 hexose catabolism P 0 0 0 0 0 5 36 68 13.9 52.9 2.45 181 0.0.5.20.8.8.7.0.4 6007 glucose catabolism P 0 2 2 0 100 5 35 67 14.3 52.2 2.523 182 0.0.5.20.8.8.7.0.4.0 6096 glycolysis P 4 29 55 13.8 52.7 4 29 55 13.8 52.7 2.174 183 0.0.5.20.8.22.1.3.9 19941 modification-dependent protein catabolism P 0 0 0 0 0 11 69 143 15.9 48.3 4.186 184 0.0.5.20.8.22.1.3.9.3 6511 ubiquitin-dependent protein catabolism P 11 67 140 16.4 47.9 11 69 143 15.9 48.3 4.186 185 0.0.5.20.9 6731 coenzymes and prosthetic group metabolism P 0 0 0 0 0 9 67 129 13.4 51.9 3.178 186 0.0.5.20.9.0 6732 coenzyme metabolism P 0 0 0 0 0 8 55 110 14.5 50 3.257 187 0.0.5.20.9.0.3 46034 ATP metabolism P 0 3 4 0 75 5 21 34 23.8 61.8 3.957 188 0.0.5.20.9.0.3.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 189 0.0.5.20.9.0.6 9108 coenzyme biosynthesis P 0 0 2 0 0 7 35 73 20 47.9 4.077 190 0.0.5.20.9.0.6.3 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 191 0.0.5.20.9.0.12 6752 group transfer coenzyme metabolism P 0 0 0 0 0 6 27 43 22.2 62.8 4.11 192 0.0.5.20.9.0.12.2 6753 nucleoside phosphate metabolism P 0 0 0 0 0 5 17 29 29.4 58.6 4.62 193 0.0.5.20.9.0.12.2.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 194 0.0.5.20.9.1 46138 coenzymes and prosthetic group biosynthesis P 0 0 0 0 0 8 44 89 18.2 49.4 4.02 195 0.0.5.20.9.1.0 9108 coenzyme biosynthesis P 0 0 2 0 0 7 35 73 20 47.9 4.077 196 0.0.5.20.9.1.0.3 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 197 0.0.5.20.12 6091 energy pathways P 7 73 89 9.6 82 14 151 225 9.3 67.1 2.429 198 0.0.5.20.12.0.3 6092 main pathways of carbohydrate metabolism P 0 0 2 0 0 8 58 108 13.8 53.7 3.081 199 0.0.5.20.12.0.3.2 6096 glycolysis P 4 29 55 13.8 52.7 4 29 55 13.8 52.7 2.174 200 0.0.5.20.12.0.3.6 6099 tricarboxylic acid cycle P 4 17 29 23.5 58.6 4 17 29 23.5 58.6 3.506 201 0.0.5.20.25 6139 "nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism" P 2 23 29 8.7 79.3 83 1363 2975 6.1 45.8 2.043 202 0.0.5.20.25.0 6259 DNA metabolism P 0 16 23 0 69.6 27 280 614 9.6 45.6 3.631 203 0.0.5.20.25.0.4 6323 DNA packaging P 1 9 11 11.1 81.8 9 72 201 12.5 35.8 2.931 204 0.0.5.20.25.0.4.0 6325 establishment and/or maintenance of chromatin architecture P 0 6 16 0 37.5 8 63 192 12.7 32.8 2.812 205 0.0.5.20.25.0.4.0.1 16568 chromatin modification P 2 18 40 11.1 45 5 35 73 14.3 47.9 2.523 206 0.0.5.20.25.0.4.0.1.1 16582 non-covalent chromatin modification P 0 0 0 0 0 3 15 34 20 44.1 2.665 207 0.0.5.20.25.0.4.0.1.1.0 6338 chromatin modeling P 3 13 17 23.1 76.5 3 15 34 20 44.1 2.665 208 0.0.5.20.25.0.6 6310 DNA recombination P 2 14 41 14.3 34.1 4 30 69 13.3 43.5 2.096 209 0.0.5.20.25.0.7.5 6302 double-strand break repair P 3 4 8 75 50 3 6 14 50 42.9 5.056 210 0.0.5.20.25.0.8 6260 DNA replication P 8 50 94 16 53.2 11 83 186 13.3 44.6 3.465 211 0.0.5.20.25.6 9117 nucleotide metabolism P 1 8 15 12.5 53.3 11 72 141 15.3 51.1 4.017 212 0.0.5.20.25.6.6 9141 nucleoside triphosphate metabolism P 0 0 0 0 0 6 31 54 19.4 57.4 3.671 213 0.0.5.20.25.6.6.1 9142 nucleoside triphosphate biosynthesis P 0 2 3 0 66.7 5 26 44 19.2 59.1 3.332 214 0.0.5.20.25.6.6.1.1 9145 purine nucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 215 0.0.5.20.25.6.6.1.1.1 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 216 0.0.5.20.25.6.6.1.1.1.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 217 0.0.5.20.25.6.6.1.3 9201 ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 218 0.0.5.20.25.6.6.1.3.0 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 219 0.0.5.20.25.6.6.1.3.0.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 220 0.0.5.20.25.6.6.3 9144 purine nucleoside triphosphate metabolism P 0 0 0 0 0 5 30 48 16.7 62.5 2.935 221 0.0.5.20.25.6.6.3.1 9145 purine nucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 222 0.0.5.20.25.6.6.3.1.1 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 223 0.0.5.20.25.6.6.3.1.1.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 224 0.0.5.20.25.6.6.3.3 9205 purine ribonucleoside triphosphate metabolism P 0 0 0 0 0 5 30 48 16.7 62.5 2.935 225 0.0.5.20.25.6.6.3.3.0 46034 ATP metabolism P 0 3 4 0 75 5 21 34 23.8 61.8 3.957 226 0.0.5.20.25.6.6.3.3.0.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 227 0.0.5.20.25.6.6.3.3.3 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 228 0.0.5.20.25.6.6.3.3.3.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 229 0.0.5.20.25.6.6.5 9199 ribonucleoside triphosphate metabolism P 0 0 0 0 0 5 30 48 16.7 62.5 2.935 230 0.0.5.20.25.6.6.5.0 9205 purine ribonucleoside triphosphate metabolism P 0 0 0 0 0 5 30 48 16.7 62.5 2.935 231 0.0.5.20.25.6.6.5.0.0 46034 ATP metabolism P 0 3 4 0 75 5 21 34 23.8 61.8 3.957 232 0.0.5.20.25.6.6.5.0.0.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 233 0.0.5.20.25.6.6.5.0.3 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 234 0.0.5.20.25.6.6.5.0.3.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 235 0.0.5.20.25.6.6.5.2 9201 ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 236 0.0.5.20.25.6.6.5.2.0 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 237 0.0.5.20.25.6.6.5.2.0.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 238 0.0.5.20.25.6.7 9165 nucleotide biosynthesis P 2 6 12 33.3 50 10 54 102 18.5 52.9 4.57 239 0.0.5.20.25.6.7.4 9142 nucleoside triphosphate biosynthesis P 0 2 3 0 66.7 5 26 44 19.2 59.1 3.332 240 0.0.5.20.25.6.7.4.1 9145 purine nucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 241 0.0.5.20.25.6.7.4.1.1 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 242 0.0.5.20.25.6.7.4.1.1.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 243 0.0.5.20.25.6.7.4.3 9201 ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 244 0.0.5.20.25.6.7.4.3.0 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 245 0.0.5.20.25.6.7.4.3.0.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 246 0.0.5.20.25.6.7.5 6164 purine nucleotide biosynthesis P 2 3 10 66.7 30 8 34 61 23.5 55.7 4.964 247 0.0.5.20.25.6.7.5.3 9145 purine nucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 248 0.0.5.20.25.6.7.5.3.1 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 249 0.0.5.20.25.6.7.5.3.1.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 250 0.0.5.20.25.6.7.5.4 9152 purine ribonucleotide biosynthesis P 1 1 1 100 100 6 31 57 19.4 54.4 3.671 251 0.0.5.20.25.6.7.5.4.2 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 252 0.0.5.20.25.6.7.5.4.2.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 253 0.0.5.20.25.6.7.8 9260 ribonucleotide biosynthesis P 0 0 0 0 0 6 35 63 17.1 55.6 3.3 254 0.0.5.20.25.6.7.8.0 9152 purine ribonucleotide biosynthesis P 1 1 1 100 100 6 31 57 19.4 54.4 3.671 255 0.0.5.20.25.6.7.8.0.2 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 256 0.0.5.20.25.6.7.8.0.2.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 257 0.0.5.20.25.6.7.8.4 9201 ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 258 0.0.5.20.25.6.7.8.4.0 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 259 0.0.5.20.25.6.7.8.4.0.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 260 0.0.5.20.25.6.10 6163 purine nucleotide metabolism P 0 1 1 0 100 8 40 69 20 58 4.361 261 0.0.5.20.25.6.10.3 9144 purine nucleoside triphosphate metabolism P 0 0 0 0 0 5 30 48 16.7 62.5 2.935 262 0.0.5.20.25.6.10.3.1 9145 purine nucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 263 0.0.5.20.25.6.10.3.1.1 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 264 0.0.5.20.25.6.10.3.1.1.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 265 0.0.5.20.25.6.10.3.3 9205 purine ribonucleoside triphosphate metabolism P 0 0 0 0 0 5 30 48 16.7 62.5 2.935 266 0.0.5.20.25.6.10.3.3.0 46034 ATP metabolism P 0 3 4 0 75 5 21 34 23.8 61.8 3.957 267 0.0.5.20.25.6.10.3.3.0.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 268 0.0.5.20.25.6.10.3.3.3 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 269 0.0.5.20.25.6.10.3.3.3.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 270 0.0.5.20.25.6.10.4 6164 purine nucleotide biosynthesis P 2 3 10 66.7 30 8 34 61 23.5 55.7 4.964 271 0.0.5.20.25.6.10.4.3 9145 purine nucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 272 0.0.5.20.25.6.10.4.3.1 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 273 0.0.5.20.25.6.10.4.3.1.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 274 0.0.5.20.25.6.10.4.4 9152 purine ribonucleotide biosynthesis P 1 1 1 100 100 6 31 57 19.4 54.4 3.671 275 0.0.5.20.25.6.10.4.4.2 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 276 0.0.5.20.25.6.10.4.4.2.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 277 0.0.5.20.25.6.10.6 9150 purine ribonucleotide metabolism P 0 0 0 0 0 6 35 62 17.1 56.5 3.3 278 0.0.5.20.25.6.10.6.2 9205 purine ribonucleoside triphosphate metabolism P 0 0 0 0 0 5 30 48 16.7 62.5 2.935 279 0.0.5.20.25.6.10.6.2.0 46034 ATP metabolism P 0 3 4 0 75 5 21 34 23.8 61.8 3.957 280 0.0.5.20.25.6.10.6.2.0.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 281 0.0.5.20.25.6.10.6.2.3 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 282 0.0.5.20.25.6.10.6.2.3.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 283 0.0.5.20.25.6.10.6.3 9152 purine ribonucleotide biosynthesis P 1 1 1 100 100 6 31 57 19.4 54.4 3.671 284 0.0.5.20.25.6.10.6.3.2 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 285 0.0.5.20.25.6.10.6.3.2.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 286 0.0.5.20.25.6.14 9259 ribonucleotide metabolism P 0 0 0 0 0 6 40 69 15 58 2.906 287 0.0.5.20.25.6.14.0 9150 purine ribonucleotide metabolism P 0 0 0 0 0 6 35 62 17.1 56.5 3.3 288 0.0.5.20.25.6.14.0.2 9205 purine ribonucleoside triphosphate metabolism P 0 0 0 0 0 5 30 48 16.7 62.5 2.935 289 0.0.5.20.25.6.14.0.2.0 46034 ATP metabolism P 0 3 4 0 75 5 21 34 23.8 61.8 3.957 290 0.0.5.20.25.6.14.0.2.0.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 291 0.0.5.20.25.6.14.0.2.3 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 292 0.0.5.20.25.6.14.0.2.3.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 293 0.0.5.20.25.6.14.0.3 9152 purine ribonucleotide biosynthesis P 1 1 1 100 100 6 31 57 19.4 54.4 3.671 294 0.0.5.20.25.6.14.0.3.2 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 295 0.0.5.20.25.6.14.0.3.2.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 296 0.0.5.20.25.6.14.4 9199 ribonucleoside triphosphate metabolism P 0 0 0 0 0 5 30 48 16.7 62.5 2.935 297 0.0.5.20.25.6.14.4.0 9205 purine ribonucleoside triphosphate metabolism P 0 0 0 0 0 5 30 48 16.7 62.5 2.935 298 0.0.5.20.25.6.14.4.0.0 46034 ATP metabolism P 0 3 4 0 75 5 21 34 23.8 61.8 3.957 299 0.0.5.20.25.6.14.4.0.0.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 300 0.0.5.20.25.6.14.4.0.3 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 301 0.0.5.20.25.6.14.4.0.3.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 302 0.0.5.20.25.6.14.4.2 9201 ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 303 0.0.5.20.25.6.14.4.2.0 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 304 0.0.5.20.25.6.14.4.2.0.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 305 0.0.5.20.25.6.14.5 9260 ribonucleotide biosynthesis P 0 0 0 0 0 6 35 63 17.1 55.6 3.3 306 0.0.5.20.25.6.14.5.0 9152 purine ribonucleotide biosynthesis P 1 1 1 100 100 6 31 57 19.4 54.4 3.671 307 0.0.5.20.25.6.14.5.0.2 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 308 0.0.5.20.25.6.14.5.0.2.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 309 0.0.5.20.25.6.14.5.4 9201 ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 310 0.0.5.20.25.6.14.5.4.0 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 5 26 43 19.2 60.5 3.332 311 0.0.5.20.25.6.14.5.4.0.1 6754 ATP biosynthesis P 5 14 22 35.7 63.6 5 17 29 29.4 58.6 4.62 312 0.0.5.20.25.10 16070 RNA metabolism P 0 2 3 0 66.7 25 175 297 14.3 58.9 5.7 313 0.0.5.20.25.10.1 16071 mRNA metabolism P 0 2 6 0 33.3 3 18 25 16.7 72 2.271 314 0.0.5.20.25.10.3 6396 RNA processing P 1 37 67 2.7 55.2 24 159 273 15.1 58.2 5.9 315 0.0.5.20.25.10.3.0 6397 mRNA processing P 3 29 44 10.3 65.9 19 96 137 19.8 70.1 6.688 316 0.0.5.20.25.10.3.0.5 398 "nuclear mRNA splicing\, via spliceosome" P 11 49 71 22.4 69 14 60 86 23.3 69.8 6.537 317 0.0.5.20.25.10.3.0.5.6 245 spliceosome assembly P 3 8 13 37.5 61.5 4 13 19 30.8 68.4 4.263 318 0.0.5.20.25.10.3.3 8380 RNA splicing P 1 7 13 14.3 53.8 14 65 97 21.5 67 6.14 319 0.0.5.20.25.10.3.3.1 375 "RNA splicing\, via transesterification reactions" P 0 0 0 0 0 14 60 86 23.3 69.8 6.537 320 0.0.5.20.25.10.3.3.1.0 377 "RNA splicing\, via transesterification reactions with bulged adenosine as nucleophile" P 0 0 0 0 0 14 60 86 23.3 69.8 6.537 321 0.0.5.20.25.10.3.3.1.0.2 398 "nuclear mRNA splicing\, via spliceosome" P 11 49 71 22.4 69 14 60 86 23.3 69.8 6.537 322 0.0.5.20.25.10.3.3.1.0.2.6 245 spliceosome assembly P 3 8 13 37.5 61.5 4 13 19 30.8 68.4 4.263 323 0.0.5.20.25.11 6350 transcription P 4 47 98 8.5 48 32 903 2072 3.5 43.6 -2.16 324 0.0.5.20.25.11.0 45449 regulation of transcription P 0 2 4 0 50 25 829 1938 3 42.8 -2.799 325 0.0.5.20.25.11.0.2 6355 "regulation of transcription\, DNA-dependent" P 20 685 1727 2.9 39.7 25 823 1924 3 42.8 -2.757 326 0.0.5.20.25.11.1 6351 "transcription\, DNA-dependent" P 1 4 6 25 66.7 32 881 2018 3.6 43.7 -2.001 327 0.0.5.20.25.11.1.2 6355 "regulation of transcription\, DNA-dependent" P 20 685 1727 2.9 39.7 25 823 1924 3 42.8 -2.757 328 0.0.5.20.35.9.19 6445 regulation of translation P 1 12 21 8.3 57.1 5 41 66 12.2 62.1 2.117 329 0.0.5.20.35.9.19.7 6446 regulation of translational initiation P 4 22 33 18.2 66.7 4 23 34 17.4 67.6 2.728 330 0.0.5.20.35.9.26 6414 translational elongation P 3 20 37 15 54.1 3 20 39 15 51.3 2.052 331 0.0.5.20.35.9.29.3 6446 regulation of translational initiation P 4 22 33 18.2 66.7 4 23 34 17.4 67.6 2.728 332 0.0.5.20.35.10.3.9 19941 modification-dependent protein catabolism P 0 0 0 0 0 11 69 143 15.9 48.3 4.186 333 0.0.5.20.35.10.3.9.3 6511 ubiquitin-dependent protein catabolism P 11 67 140 16.4 47.9 11 69 143 15.9 48.3 4.186 334 0.0.5.20.35.12 6457 protein folding P 11 74 151 14.9 49 11 74 151 14.9 49 3.909 335 0.0.5.33.2.3.5 6302 double-strand break repair P 3 4 8 75 50 3 6 14 50 42.9 5.056 336 0.0.5.34 9605 response to external stimulus P 0 5 6 0 83.3 18 749 1783 2.4 42 -3.457 337 0.0.5.34.3 9607 response to biotic stimulus P 0 2 2 0 100 10 512 1044 2 49 -3.291 338 0.0.5.34.3.1 6952 defense response P 0 34 73 0 46.6 7 466 953 1.5 48.9 -3.59 339 0.0.5.34.3.1.3 6955 immune response P 5 229 574 2.2 39.9 7 436 889 1.6 49 -3.363 340 0.0.5.34.3.8 9613 response to pest/pathogen/parasite P 0 4 13 0 30.8 5 280 432 1.8 64.8 -2.522 341 0.0.5.35.3.3.5 6302 double-strand break repair P 3 4 8 75 50 3 6 14 50 42.9 5.056 342 0.0.5.35.13 9613 response to pest/pathogen/parasite P 0 4 13 0 30.8 5 280 432 1.8 64.8 -2.522 343 0.1 5575 cellular_component C 0 0 0 0 0 295 5407 12138 5.5 44.5 3.184 344 0.1.0 5623 cell C 0 2 2 0 100 274 4787 10473 5.7 45.7 4.053 345 0.1.0.7 5622 intracellular C 8 235 665 3.4 35.3 233 3212 6357 7.3 50.5 7.944 346 0.1.0.7.4 5694 chromosome C 1 8 48 12.5 16.7 8 57 163 14 35 3.138 347 0.1.0.7.4.1 785 chromatin C 4 22 58 18.2 37.9 5 35 128 14.3 27.3 2.523 348 0.1.0.7.7 5737 cytoplasm C 26 377 601 6.9 62.7 147 1758 2986 8.4 58.9 7.456 349 0.1.0.7.7.10.0 15629 actin cytoskeleton C 5 56 90 8.9 62.2 11 120 227 9.2 52.9 2.108 350 0.1.0.7.7.11 5829 cytosol C 16 115 156 13.9 73.7 21 193 283 10.9 68.2 3.795 351 0.1.0.7.7.11.14 502 proteasome complex (sensu Eukarya) C 1 1 1 100 100 8 22 30 36.4 73.3 6.754 352 0.1.0.7.7.11.14.0 5839 proteasome core complex (sensu Eukarya) C 7 16 22 43.8 72.7 7 16 22 43.8 72.7 7.114 353 0.1.0.7.7.16 5783 endoplasmic reticulum C 19 166 260 11.4 63.8 32 232 362 13.8 64.1 6.241 354 0.1.0.7.7.16.5 502 proteasome complex (sensu Eukarya) C 1 1 1 100 100 8 22 30 36.4 73.3 6.754 355 0.1.0.7.7.16.5.0 5839 proteasome core complex (sensu Eukarya) C 7 16 22 43.8 72.7 7 16 22 43.8 72.7 7.114 356 0.1.0.7.7.38 5739 mitochondrion C 39 296 445 13.2 66.5 43 335 541 12.8 61.9 6.734 357 0.1.0.7.7.38.4 5759 mitochondrial matrix C 3 19 29 15.8 65.5 6 42 64 14.3 65.6 2.766 358 0.1.0.7.7.38.4.7 5761 mitochondrial ribosome C 1 6 7 16.7 85.7 3 16 26 18.8 61.5 2.524 359 0.1.0.7.7.38.5 5740 mitochondrial membrane C 1 7 13 14.3 53.8 8 73 159 11 45.9 2.344 360 0.1.0.7.7.38.5.0 5743 mitochondrial inner membrane C 2 24 59 8.3 40.7 6 52 113 11.5 46 2.168 361 0.1.0.7.7.38.5.0.7 5753 proton-transporting ATP synthase complex (sensu Eukarya) C 4 11 12 36.4 91.7 4 11 14 36.4 78.6 4.772 362 0.1.0.7.7.54.3 313 organellar ribosome C 0 0 0 0 0 3 16 26 18.8 61.5 2.524 363 0.1.0.7.7.54.3.0 5761 mitochondrial ribosome C 1 6 7 16.7 85.7 3 16 26 18.8 61.5 2.524 364 0.1.0.7.21 5634 nucleus C 88 1391 2847 6.3 48.9 108 1541 3107 7 49.6 4.081 365 0.1.0.7.21.15.0 5637 nuclear inner membrane C 1 1 1 100 100 3 7 7 42.9 100 4.594 366 0.1.0.7.21.17 5730 nucleolus C 3 28 40 10.7 70 6 49 77 12.2 63.6 2.331 367 0.1.0.7.21.17.9 5732 small nucleolar ribonucleoprotein complex C 3 15 27 20 55.6 3 15 27 20 55.6 2.665 368 0.1.0.7.21.22 502 proteasome complex (sensu Eukarya) C 1 1 1 100 100 8 22 30 36.4 73.3 6.754 369 0.1.0.7.21.22.0 5839 proteasome core complex (sensu Eukarya) C 7 16 22 43.8 72.7 7 16 22 43.8 72.7 7.114 370 0.1.0.7.21.28 5681 spliceosome complex C 5 22 40 22.7 55 5 27 46 18.5 58.7 3.226 371 0.1.0.7.23 45259 proton-transporting ATP synthase complex C 0 0 0 0 0 4 11 14 36.4 78.6 4.772 372 0.1.0.7.23.2 5753 proton-transporting ATP synthase complex (sensu Eukarya) C 4 11 12 36.4 91.7 4 11 14 36.4 78.6 4.772 373 0.1.0.7.32 30529 ribonucleoprotein complex C 4 29 46 13.8 63 20 181 334 11 54.2 3.777 374 0.1.0.7.32.5.3 313 organellar ribosome C 0 0 0 0 0 3 16 26 18.8 61.5 2.524 375 0.1.0.7.32.5.3.0 5761 mitochondrial ribosome C 1 6 7 16.7 85.7 3 16 26 18.8 61.5 2.524 376 0.1.0.7.32.8 5732 small nucleolar ribonucleoprotein complex C 3 15 27 20 55.6 3 15 27 20 55.6 2.665 377 0.1.0.7.32.9 5681 spliceosome complex C 5 22 40 22.7 55 5 27 46 18.5 58.7 3.226 378 0.1.0.8 16020 membrane C 16 364 1248 4.4 29.2 83 2114 4998 3.9 42.3 -2.727 379 0.1.0.8.1 12505 endomembrane system C 0 1 1 0 100 9 95 151 9.5 62.9 2.01 380 0.1.0.8.1.3.0 5637 nuclear inner membrane C 1 1 1 100 100 3 7 7 42.9 100 4.594 381 0.1.0.8.6 19866 inner membrane C 1 17 29 5.9 58.6 7 61 126 11.5 48.4 2.327 382 0.1.0.8.6.0 5743 mitochondrial inner membrane C 2 24 59 8.3 40.7 6 52 113 11.5 46 2.168 383 0.1.0.8.6.0.7 5753 proton-transporting ATP synthase complex (sensu Eukarya) C 4 11 12 36.4 91.7 4 11 14 36.4 78.6 4.772 384 0.1.0.8.7 16021 integral to membrane C 34 924 2379 3.7 38.8 55 1638 3498 3.4 46.8 -3.496 385 0.1.0.8.7.4 5887 integral to plasma membrane C 14 648 965 2.2 67.2 17 749 1159 2.3 64.6 -3.634 386 0.1.0.8.7.10 16469 proton-transporting two-sector ATPase complex C 2 8 9 25 88.9 5 16 20 31.2 80 4.819 387 0.1.0.8.7.10.0 45255 hydrogen-translocating F-type ATPase complex C 0 0 0 0 0 4 11 14 36.4 78.6 4.772 388 0.1.0.8.7.10.0.3 5753 proton-transporting ATP synthase complex (sensu Eukarya) C 4 11 12 36.4 91.7 4 11 14 36.4 78.6 4.772 389 0.1.0.8.9 5740 mitochondrial membrane C 1 7 13 14.3 53.8 8 73 159 11 45.9 2.344 390 0.1.0.8.9.0 5743 mitochondrial inner membrane C 2 24 59 8.3 40.7 6 52 113 11.5 46 2.168 391 0.1.0.8.9.0.7 5753 proton-transporting ATP synthase complex (sensu Eukarya) C 4 11 12 36.4 91.7 4 11 14 36.4 78.6 4.772 392 0.1.0.8.13 5886 plasma membrane C 8 178 260 4.5 68.5 29 1006 1577 2.9 63.8 -3.338 393 0.1.0.8.13.19 5887 integral to plasma membrane C 14 648 965 2.2 67.2 17 749 1159 2.3 64.6 -3.634 394 0.1.2 5576 extracellular C 2 182 552 1.1 33 7 519 1108 1.3 46.8 -3.971 395 0.1.2.2 5615 extracellular space C 4 212 305 1.9 69.5 4 216 309 1.9 69.9 -2.159 396 0.1.4 8370 obsolete cellular component C 0 0 0 0 0 23 130 167 17.7 77.8 6.695 397 0.1.4.0 5837 26S proteasome C 14 30 35 46.7 85.7 14 30 35 46.7 85.7 10.485 398 0.1.4.65 776 kinetochore C 4 13 14 30.8 92.9 4 13 14 30.8 92.9 4.263 399 0.2.4.16 8289 lipid binding F 3 28 55 10.7 50.9 9 91 139 9.9 65.5 2.15 400 0.2.4.16.0 5541 acyl-CoA or acyl binding F 0 0 0 0 0 4 30 42 13.3 71.4 2.096 401 0.2.4.19 46872 metal ion binding F 4 11 47 36.4 23.4 19 657 1566 2.9 42 -2.611 402 0.2.4.19.0 5509 calcium ion binding F 6 314 796 1.9 39.4 6 317 805 1.9 39.4 -2.602 403 0.2.4.19.3 46914 transition metal ion binding F 0 0 0 0 0 6 274 617 2.2 44.4 -2.181 404 0.2.4.19.3.7 8270 zinc ion binding F 3 205 499 1.5 41.1 3 205 499 1.5 41.1 -2.361 405 0.2.4.22 3676 nucleic acid binding F 11 154 665 7.1 23.2 92 1418 3458 6.5 41 2.865 406 0.2.4.22.0.21 3697 single-stranded DNA binding F 5 23 30 21.7 76.7 5 23 30 21.7 76.7 3.686 407 0.2.4.22.0.23 3700 transcription factor activity F 12 444 992 2.7 44.8 12 455 1008 2.6 45.1 -2.396 408 0.2.4.22.1 3723 RNA binding F 23 254 450 9.1 56.4 35 315 560 11.1 56.2 5.084 409 0.2.4.22.1.4 3725 double-stranded RNA binding F 3 18 37 16.7 48.6 3 18 37 16.7 48.6 2.271 410 0.2.4.22.1.5 3729 mRNA binding F 5 9 11 55.6 81.8 16 70 95 22.9 73.7 6.883 411 0.2.4.22.1.5.5 8248 pre-mRNA splicing factor activity F 10 50 71 20 70.4 10 50 71 20 70.4 4.879 412 0.2.4.22.2 8135 "translation factor activity\, nucleic acid binding" F 0 4 5 0 80 7 68 112 10.3 60.7 2.009 413 0.2.4.22.2.4 3746 translation elongation factor activity F 3 18 30 16.7 60 3 18 32 16.7 56.2 2.271 414 0.2.4.23 166 nucleotide binding F 12 79 176 15.2 44.9 61 820 1910 7.4 42.9 3.4 415 0.2.4.23.2 17076 purine nucleotide binding F 0 1 1 0 100 61 813 1892 7.5 43 3.472 416 0.2.4.23.2.0 30554 adenyl nucleotide binding F 0 0 0 0 0 45 660 1548 6.8 42.6 2.243 417 0.2.4.23.2.0.3 5524 ATP binding F 45 652 1535 6.9 42.5 45 652 1535 6.9 42.5 2.33 418 0.2.4.23.2.1 19001 guanyl nucleotide binding F 0 0 0 0 0 16 160 353 10 45.3 2.93 419 0.2.4.23.2.1.2 5525 GTP binding F 16 156 348 10.3 44.8 16 156 348 10.3 44.8 3.041 420 0.2.4.32 5102 receptor binding F 2 43 69 4.7 62.3 6 282 552 2.1 51.1 -2.263 421 0.2.5.19 4386 helicase activity F 0 8 21 0 38.1 9 71 179 12.7 39.7 2.978 422 0.2.5.19.0 8026 ATP dependent helicase activity F 6 46 121 13 38 9 65 161 13.8 40.4 3.283 423 0.2.5.19.4 3724 RNA helicase activity F 2 7 9 28.6 77.8 4 21 29 19 72.4 2.955 424 0.2.5.20 16787 hydrolase activity F 28 515 956 5.4 53.9 69 1042 2387 6.6 43.7 2.592 425 0.2.5.20.1 16817 "hydrolase activity\, acting on acid anhydrides" F 0 0 0 0 0 35 315 688 11.1 45.8 5.084 426 0.2.5.20.1.1 16818 "hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides" F 0 0 0 0 0 32 298 653 10.7 45.6 4.637 427 0.2.5.20.1.1.6 16887 ATPase activity F 1 9 25 11.1 36 17 148 334 11.5 44.3 3.654 428 0.2.5.20.1.1.6.0 42623 "ATPase activity\, coupled" F 0 0 0 0 0 16 145 327 11 44.3 3.363 429 0.2.5.20.1.1.6.0.0 8026 ATP dependent helicase activity F 6 46 121 13 38 9 65 161 13.8 40.4 3.283 430 0.2.5.20.1.1.6.0.2 8094 DNA dependent ATPase activity F 1 8 20 12.5 40 3 16 44 18.8 36.4 2.524 431 0.2.5.20.1.1.20 3924 GTPase activity F 2 16 36 12.5 44.4 13 135 287 9.6 47 2.487 432 0.2.5.20.1.1.20.4 3925 small monomeric GTPase activity F 5 26 71 19.2 36.6 9 89 196 10.1 45.4 2.223 433 0.2.5.20.1.3 16821 "hydrolase activity\, acting on acid anhydrides\, involved in cellular and subcellular movement" F 0 0 0 0 0 3 17 36 17.6 47.2 2.393 434 0.2.5.20.10 16788 "hydrolase activity\, acting on ester bonds" F 0 3 7 0 42.9 7 291 698 2.4 41.7 -2.078 435 0.2.5.23 16301 kinase activity F 1 77 164 1.3 47 10 447 1022 2.2 43.7 -2.775 436 0.2.5.23.43 4672 protein kinase activity F 2 19 77 10.5 24.7 8 325 758 2.5 42.9 -2.154 437 0.2.5.33 16491 oxidoreductase activity F 24 250 472 9.6 53 29 359 748 8.1 48 2.74 438 0.2.5.33.27 16614 "oxidoreductase activity\, acting on CH-OH group of donors" F 0 1 3 0 33.3 8 63 122 12.7 51.6 2.812 439 0.2.5.33.27.10 16616 "oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor" F 0 4 7 0 57.1 8 60 118 13.3 50.8 2.97 440 0.2.5.33.27.10.55 3857 3-hydroxyacyl-CoA dehydrogenase activity F 3 6 6 50 100 3 6 6 50 100 5.056 441 0.2.5.33.32 16651 "oxidoreductase activity\, acting on NADH or NADPH" F 0 0 0 0 0 10 42 77 23.8 54.5 5.604 442 0.2.5.33.32.5 16659 "oxidoreductase activity\, acting on NADH or NADPH\, other acceptor" F 0 0 0 0 0 6 28 38 21.4 73.7 3.992 443 0.2.5.33.32.5.3 3954 NADH dehydrogenase activity F 6 26 36 23.1 72.2 6 26 36 23.1 72.2 4.233 444 0.2.5.33.32.6 16655 "oxidoreductase activity\, acting on NADH or NADPH\, quinone or similar compound as acceptor" F 0 0 0 0 0 8 29 57 27.6 50.9 5.587 445 0.2.5.33.32.6.3 8137 NADH dehydrogenase (ubiquinone) activity F 7 26 54 26.9 48.1 7 26 54 26.9 48.1 5.134 446 0.2.5.47 16740 transferase activity F 21 562 1146 3.7 49 25 819 1783 3.1 45.9 -2.729 447 0.2.5.47.16 16772 "transferase activity\, transferring phosphorus-containing groups" F 0 3 5 0 60 12 474 1063 2.5 44.6 -2.559 448 0.2.5.47.16.6 16773 "phosphotransferase activity\, alcohol group as acceptor" F 0 4 5 0 80 9 383 871 2.3 44 -2.452 449 0.2.5.47.16.6.89 4672 protein kinase activity F 2 19 77 10.5 24.7 8 325 758 2.5 42.9 -2.154 450 0.2.11 3754 chaperone activity F 8 58 118 13.8 49.2 14 92 169 15.2 54.4 4.521 451 0.2.18.3 3777 microtubule motor activity F 4 15 48 26.7 31.2 4 16 52 25 30.8 3.671 452 0.2.20.267 8575 proteasome ATPase activity F 3 4 4 75 100 3 4 4 75 100 6.421 453 0.2.23 4871 signal transducer activity F 6 134 277 4.5 48.4 27 1188 3058 2.3 38.8 -4.742 454 0.2.23.5 4872 receptor activity F 9 344 1085 2.6 31.7 15 734 2183 2 33.6 -3.89 455 0.2.23.5.16 4888 transmembrane receptor activity F 1 71 119 1.4 59.7 9 500 1597 1.8 31.3 -3.412 456 0.2.23.6 5102 receptor binding F 2 43 69 4.7 62.3 6 282 552 2.1 51.1 -2.263 457 0.2.24.21 3735 structural constituent of ribosome F 11 119 240 9.2 49.6 11 119 240 9.2 49.6 2.138 458 0.2.27 30528 transcription regulator activity F 0 5 12 0 41.7 19 631 1242 3 50.8 -2.41 459 0.2.27.6 3700 transcription factor activity F 12 444 992 2.7 44.8 12 455 1008 2.6 45.1 -2.396 460 0.2.28.1 8135 "translation factor activity\, nucleic acid binding" F 0 4 5 0 80 7 68 112 10.3 60.7 2.009 461 0.2.28.1.4 3746 translation elongation factor activity F 3 18 30 16.7 60 3 18 32 16.7 56.2 2.271 462 0.2.29 5215 transporter activity F 8 174 418 4.6 41.6 62 984 2128 6.3 46.2 2.008 463 0.2.29.5 5386 carrier activity F 1 10 16 10 62.5 21 255 564 8.2 45.2 2.408 464 0.2.29.5.3 15399 primary active transporter activity F 0 0 0 0 0 14 128 264 10.9 48.5 3.105 465 0.2.29.5.3.5 8137 NADH dehydrogenase (ubiquinone) activity F 7 26 54 26.9 48.1 7 26 54 26.9 48.1 5.134 466 0.2.29.6 15267 channel/pore class transporter activity F 0 5 9 0 55.6 4 218 468 1.8 46.6 -2.181 467 0.2.29.6.0 15268 alpha-type channel activity F 0 0 0 0 0 4 212 451 1.9 47 -2.115 468 0.2.29.8.17 3954 NADH dehydrogenase activity F 6 26 36 23.1 72.2 6 26 36 23.1 72.2 4.233 469 0.2.29.11 15075 ion transporter activity F 0 11 17 0 64.7 24 177 379 13.6 46.7 5.285 470 0.2.29.11.1 8324 cation transporter activity F 1 8 26 12.5 30.8 22 138 276 15.9 50 5.949 471 0.2.29.11.1.4 15077 monovalent inorganic cation transporter activity F 0 1 4 0 25 17 79 164 21.5 48.2 6.768 472 0.2.29.11.1.4.0 15078 hydrogen ion transporter activity F 8 21 32 38.1 65.6 17 73 154 23.3 47.4 7.2 473 0.2.29.11.1.4.0.8 8137 NADH dehydrogenase (ubiquinone) activity F 7 26 54 26.9 48.1 7 26 54 26.9 48.1 5.134 474 0.2.29.11.1.4.3 15081 sodium ion transporter activity F 0 2 2 0 100 7 29 57 24.1 50.9 4.734 475 0.2.29.11.1.4.3.0 8137 NADH dehydrogenase (ubiquinone) activity F 7 26 54 26.9 48.1 7 26 54 26.9 48.1 5.134 476 0.2.29.11.2 46873 metal ion transporter activity F 1 8 19 12.5 42.1 9 61 104 14.8 58.7 3.506 477 0.2.29.11.2.7 15081 sodium ion transporter activity F 0 2 2 0 100 7 29 57 24.1 50.9 4.734 478 0.2.29.11.2.7.0 8137 NADH dehydrogenase (ubiquinone) activity F 7 26 54 26.9 48.1 7 26 54 26.9 48.1 5.134 479 0.2.29.25 8565 protein transporter activity F 16 165 264 9.7 62.5 16 180 285 8.9 63.2 2.42 Cluster n°7 Index Path GOID GO Name GO Type Number Changed Local Number Measured Local Number in GO Local Percent Changed Local Percent Present Local Number Changed Number Measured Number in GO Percent Changed Percent Present Z Score PermuteP AdjustedP 1 0 8150 biological_process P 0 0 0 0 0 122 6136 14261 2 43 2.134 2 0.0.2.0.2.2 19226 transmission of nerve impulse P 0 1 1 0 100 7 163 257 4.3 63.4 2.328 3 0.0.2.0.2.2.3 7268 synaptic transmission P 4 126 202 3.2 62.4 7 161 255 4.3 63.1 2.364 4 0.0.2.0.2.2.3.2 1505 regulation of neurotransmitter levels P 0 2 2 0 100 3 27 38 11.1 71.1 3.565 5 0.0.5.20.5.21 8610 lipid biosynthesis P 0 6 6 0 100 5 109 168 4.6 64.9 2.124 6 0.0.5.20.6.6 16052 carbohydrate catabolism P 0 0 0 0 0 3 47 87 6.4 54 2.303 7 0.0.5.20.8 9056 catabolism P 0 1 1 0 100 16 502 1047 3.2 47.9 2.285 8 0.0.5.20.8.8 16052 carbohydrate catabolism P 0 0 0 0 0 3 47 87 6.4 54 2.303 9 0.0.5.20.20 6629 lipid metabolism P 1 77 129 1.3 59.7 11 318 519 3.5 61.3 2.161 10 0.0.5.20.20.4 8610 lipid biosynthesis P 0 6 6 0 100 5 109 168 4.6 64.9 2.124 11 0.0.5.20.25.11 6350 transcription P 1 47 98 2.1 48 25 903 2072 2.8 43.6 2.167 12 0.0.5.20.25.11.0 45449 regulation of transcription P 0 2 4 0 50 24 829 1938 2.9 42.8 2.351 13 0.0.5.20.25.11.0.2 6355 "regulation of transcription\, DNA-dependent" P 21 685 1727 3.1 39.7 24 823 1924 2.9 42.8 2.389 14 0.0.5.20.25.11.1 6351 "transcription\, DNA-dependent" P 0 4 6 0 66.7 25 881 2018 2.8 43.7 2.299 15 0.0.5.20.25.11.1.2 6355 "regulation of transcription\, DNA-dependent" P 21 685 1727 3.1 39.7 24 823 1924 2.9 42.8 2.389 16 0.2.4.22.0 3677 DNA binding F 8 444 1134 1.8 39.2 29 969 2234 3 43.4 2.813 17 0.2.4.22.0.23 3700 transcription factor activity F 19 444 992 4.3 44.8 19 455 1008 4.2 45.1 3.782 18 0.2.5.20.13.5 4175 endopeptidase activity F 0 18 24 0 75 7 158 352 4.4 44.9 2.419 19 0.2.5.20.13.5.3 4222 metalloendopeptidase activity F 2 33 81 6.1 40.7 4 55 114 7.3 48.2 2.983 20 0.2.5.20.13.8.0 4222 metalloendopeptidase activity F 2 33 81 6.1 40.7 4 55 114 7.3 48.2 2.983 21 0.2.23.5.9 4879 ligand-dependent nuclear receptor activity F 0 1 4 0 25 3 40 71 7.5 56.3 2.648 22 0.2.23.5.9.2 3707 steroid hormone receptor activity F 3 33 59 9.1 55.9 3 37 65 8.1 56.9 2.821 23 0.2.27 30528 transcription regulator activity F 0 5 12 0 41.7 22 631 1242 3.5 50.8 3.172 24 0.2.27.6 3700 transcription factor activity F 19 444 992 4.3 44.8 19 455 1008 4.2 45.1 3.782 Cluster n°8 Index Path GOID GO Name GO Type Number Changed Local Number Measured Local Number in GO Local Percent Changed Local Percent Present Local Number Changed Number Measured Number in GO Percent Changed Percent Present Z Score PermuteP AdjustedP 1 0.0.2.0 7154 cell communication P 0 11 27 0 40.7 17 1708 3830 1 44.6 -3.843 2 0.0.2.0.7 7165 signal transduction P 5 547 954 0.9 57.3 15 1334 3088 1.1 43.2 -2.922 3 0.0.2.3.5.0 7049 cell cycle P 3 77 156 3.9 49.4 17 392 716 4.3 54.7 3.021 4 0.0.2.3.5.0.1 67 DNA replication and chromosome cycle P 0 5 6 0 83.3 6 112 225 5.4 49.8 2.328 5 0.0.2.3.5.0.1.3 6260 DNA replication P 3 50 94 6 53.2 5 83 186 6 44.6 2.419 6 0.0.2.3.5.0.1.3.3 6261 DNA dependent DNA replication P 1 8 8 12.5 100 3 46 80 6.5 57.5 2.028 7 0.0.2.3.5.0.3 279 M phase P 0 1 3 0 33.3 9 100 150 9 66.7 4.714 8 0.0.2.3.5.0.3.0 87 M phase of mitotic cell cycle P 0 2 3 0 66.7 8 78 114 10.3 68.4 4.922 9 0.0.2.3.5.0.3.0.1 7067 mitosis P 5 55 78 9.1 70.5 8 76 111 10.5 68.5 5.02 10 0.0.2.3.5.0.3.2 280 nuclear division P 0 0 0 0 0 9 96 141 9.4 68.1 4.871 11 0.0.2.3.5.0.3.2.1 7067 mitosis P 5 55 78 9.1 70.5 8 76 111 10.5 68.5 5.02 12 0.0.2.3.5.0.4 278 mitotic cell cycle P 0 0 0 0 0 14 196 354 7.1 55.4 4.838 13 0.0.2.3.5.0.4.3 86 G2/M transition of mitotic cell cycle P 1 2 6 50 33.3 3 30 44 10 68.2 2.945 14 0.0.2.3.5.0.4.4 87 M phase of mitotic cell cycle P 0 2 3 0 66.7 8 78 114 10.3 68.4 4.922 15 0.0.2.3.5.0.4.4.1 7067 mitosis P 5 55 78 9.1 70.5 8 76 111 10.5 68.5 5.02 16 0.0.2.3.5.0.4.8 84 S phase of mitotic cell cycle P 1 1 2 100 50 5 83 187 6 44.4 2.419 17 0.0.2.3.5.0.4.8.0 6260 DNA replication P 3 50 94 6 53.2 5 83 186 6 44.6 2.419 18 0.0.2.3.5.0.4.8.0.3 6261 DNA dependent DNA replication P 1 8 8 12.5 100 3 46 80 6.5 57.5 2.028 19 0.0.2.3.5.0.6 74 regulation of cell cycle P 3 107 179 2.8 59.8 10 224 357 4.5 62.7 2.389 20 0.0.2.3.5.0.6.3 45786 negative regulation of cell cycle P 3 43 66 7 65.2 3 45 69 6.7 65.2 2.073 21 0.0.3.12 9653 morphogenesis P 0 1 3 0 33.3 5 527 804 0.9 65.5 -2.006 22 0.0.5.3.5.0 7049 cell cycle P 3 77 156 3.9 49.4 17 392 716 4.3 54.7 3.021 23 0.0.5.3.5.0.1 67 DNA replication and chromosome cycle P 0 5 6 0 83.3 6 112 225 5.4 49.8 2.328 24 0.0.5.3.5.0.1.3 6260 DNA replication P 3 50 94 6 53.2 5 83 186 6 44.6 2.419 25 0.0.5.3.5.0.1.3.3 6261 DNA dependent DNA replication P 1 8 8 12.5 100 3 46 80 6.5 57.5 2.028 26 0.0.5.3.5.0.3 279 M phase P 0 1 3 0 33.3 9 100 150 9 66.7 4.714 27 0.0.5.3.5.0.3.0 87 M phase of mitotic cell cycle P 0 2 3 0 66.7 8 78 114 10.3 68.4 4.922 28 0.0.5.3.5.0.3.0.1 7067 mitosis P 5 55 78 9.1 70.5 8 76 111 10.5 68.5 5.02 29 0.0.5.3.5.0.3.2 280 nuclear division P 0 0 0 0 0 9 96 141 9.4 68.1 4.871 30 0.0.5.3.5.0.3.2.1 7067 mitosis P 5 55 78 9.1 70.5 8 76 111 10.5 68.5 5.02 31 0.0.5.3.5.0.4 278 mitotic cell cycle P 0 0 0 0 0 14 196 354 7.1 55.4 4.838 32 0.0.5.3.5.0.4.3 86 G2/M transition of mitotic cell cycle P 1 2 6 50 33.3 3 30 44 10 68.2 2.945 33 0.0.5.3.5.0.4.4 87 M phase of mitotic cell cycle P 0 2 3 0 66.7 8 78 114 10.3 68.4 4.922 34 0.0.5.3.5.0.4.4.1 7067 mitosis P 5 55 78 9.1 70.5 8 76 111 10.5 68.5 5.02 35 0.0.5.3.5.0.4.8 84 S phase of mitotic cell cycle P 1 1 2 100 50 5 83 187 6 44.4 2.419 36 0.0.5.3.5.0.4.8.0 6260 DNA replication P 3 50 94 6 53.2 5 83 186 6 44.6 2.419 37 0.0.5.3.5.0.4.8.0.3 6261 DNA dependent DNA replication P 1 8 8 12.5 100 3 46 80 6.5 57.5 2.028 38 0.0.5.3.5.0.6 74 regulation of cell cycle P 3 107 179 2.8 59.8 10 224 357 4.5 62.7 2.389 39 0.0.5.3.5.0.6.3 45786 negative regulation of cell cycle P 3 43 66 7 65.2 3 45 69 6.7 65.2 2.073 40 0.0.5.20.5.22 9059 macromolecule biosynthesis P 0 0 0 0 0 12 316 597 3.8 52.9 2.025 41 0.0.5.20.5.22.3 6412 protein biosynthesis P 8 132 243 6.1 54.3 12 316 597 3.8 52.9 2.025 42 0.0.5.20.25.0.8 6260 DNA replication P 3 50 94 6 53.2 5 83 186 6 44.6 2.419 43 0.0.5.20.25.0.8.3 6261 DNA dependent DNA replication P 1 8 8 12.5 100 3 46 80 6.5 57.5 2.028 44 0.0.5.20.25.10.3.0 6397 mRNA processing P 2 29 44 6.9 65.9 5 96 137 5.2 70.1 2.052 45 0.0.5.20.25.10.3.0.5 398 "nuclear mRNA splicing\, via spliceosome" P 3 49 71 6.1 69 5 60 86 8.3 69.8 3.285 46 0.0.5.20.25.10.3.3 8380 RNA splicing P 0 7 13 0 53.8 5 65 97 7.7 67 3.065 47 0.0.5.20.25.10.3.3.1 375 "RNA splicing\, via transesterification reactions" P 0 0 0 0 0 5 60 86 8.3 69.8 3.285 48 0.0.5.20.25.10.3.3.1.0 377 "RNA splicing\, via transesterification reactions with bulged adenosine as nucleophile" P 0 0 0 0 0 5 60 86 8.3 69.8 3.285 49 0.0.5.20.25.10.3.3.1.0.2 398 "nuclear mRNA splicing\, via spliceosome" P 3 49 71 6.1 69 5 60 86 8.3 69.8 3.285 50 0.0.5.20.35.9 6412 protein biosynthesis P 8 132 243 6.1 54.3 12 316 597 3.8 52.9 2.025 51 0.0.5.34 9605 response to external stimulus P 0 5 6 0 83.3 6 749 1783 0.8 42 -2.727 52 0.0.5.34.3.1 6952 defense response P 0 34 73 0 46.6 4 466 953 0.9 48.9 -2.016 53 0.1.0.7.7.11 5829 cytosol C 2 115 156 1.7 73.7 9 193 283 4.7 68.2 2.404 54 0.1.0.7.7.11.5 5830 cytosolic ribosome (sensu Eukarya) C 0 1 1 0 100 5 54 71 9.3 76.1 3.584 55 0.1.0.7.7.11.5.0 5842 cytosolic large ribosomal subunit (sensu Eukarya) C 3 31 40 9.7 77.5 3 31 40 9.7 77.5 2.871 56 0.1.0.7.7.38.4 5759 mitochondrial matrix C 3 19 29 15.8 65.5 3 42 64 7.1 65.6 2.214 57 0.1.0.7.7.54 5840 ribosome C 7 89 172 7.9 51.7 8 112 214 7.1 52.3 3.634 58 0.1.0.7.7.54.1 5830 cytosolic ribosome (sensu Eukarya) C 0 1 1 0 100 5 54 71 9.3 76.1 3.584 59 0.1.0.7.7.54.1.0 5842 cytosolic large ribosomal subunit (sensu Eukarya) C 3 31 40 9.7 77.5 3 31 40 9.7 77.5 2.871 60 0.1.0.7.7.54.2 15934 large ribosomal subunit C 0 4 8 0 50 3 37 54 8.1 68.5 2.481 61 0.1.0.7.7.54.2.2 5842 cytosolic large ribosomal subunit (sensu Eukarya) C 3 31 40 9.7 77.5 3 31 40 9.7 77.5 2.871 62 0.1.0.7.7.54.5 15935 small ribosomal subunit C 1 4 8 25 50 3 34 51 8.8 66.7 2.665 63 0.1.0.7.12 46821 extrachromosomal DNA C 3 36 98 8.3 36.7 3 36 100 8.3 36 2.54 64 0.1.0.7.32 30529 ribonucleoprotein complex C 0 29 46 0 63 11 181 334 6.1 54.2 3.648 65 0.1.0.7.32.5 5840 ribosome C 7 89 172 7.9 51.7 8 112 214 7.1 52.3 3.634 66 0.1.0.7.32.5.1 5830 cytosolic ribosome (sensu Eukarya) C 0 1 1 0 100 5 54 71 9.3 76.1 3.584 67 0.1.0.7.32.5.1.0 5842 cytosolic large ribosomal subunit (sensu Eukarya) C 3 31 40 9.7 77.5 3 31 40 9.7 77.5 2.871 68 0.1.0.7.32.5.2 15934 large ribosomal subunit C 0 4 8 0 50 3 37 54 8.1 68.5 2.481 69 0.1.0.7.32.5.2.2 5842 cytosolic large ribosomal subunit (sensu Eukarya) C 3 31 40 9.7 77.5 3 31 40 9.7 77.5 2.871 70 0.1.0.7.32.5.5 15935 small ribosomal subunit C 1 4 8 25 50 3 34 51 8.8 66.7 2.665 71 0.1.0.8.7.4 5887 integral to plasma membrane C 8 648 965 1.2 67.2 8 749 1159 1.1 64.6 -2.197 72 0.1.0.8.13 5886 plasma membrane C 2 178 260 1.1 68.5 10 1006 1577 1 63.8 -2.774 73 0.1.0.8.13.19 5887 integral to plasma membrane C 8 648 965 1.2 67.2 8 749 1159 1.1 64.6 -2.197 74 0.2.4.19 46872 metal ion binding F 0 11 47 0 23.4 7 657 1566 1.1 42 -2.047 75 0.2.4.22.1 3723 RNA binding F 10 254 450 3.9 56.4 16 315 560 5.1 56.2 3.618 76 0.2.4.22.1.5 3729 mRNA binding F 0 9 11 0 81.8 4 70 95 5.7 73.7 2.041 77 0.2.4.22.1.5.5 8248 pre-mRNA splicing factor activity F 4 50 71 8 70.4 4 50 71 8 70.4 2.835 78 0.2.4.22.1.9 19843 rRNA binding F 3 5 5 60 100 3 5 5 60 100 8.869 79 0.2.5.20 16787 hydrolase activity F 5 515 956 1 53.9 13 1042 2387 1.2 43.7 -2.223 80 0.2.5.23 16301 kinase activity F 7 77 164 9.1 47 16 447 1022 3.6 43.7 2.105 81 0.2.5.24 16874 ligase activity F 3 82 156 3.7 52.6 6 124 298 4.8 41.6 2.053 82 0.2.5.24.3.1.22 4842 ubiquitin-protein ligase activity F 3 46 116 6.5 39.7 3 46 116 6.5 39.7 2.028 83 0.2.5.26.4 16835 carbon-oxygen lyase activity F 0 0 0 0 0 3 37 60 8.1 61.7 2.481 84 0.2.5.26.4.2 16836 hydro-lyase activity F 0 0 2 0 0 3 34 55 8.8 61.8 2.665 85 0.2.23 4871 signal transducer activity F 1 134 277 0.7 48.4 13 1188 3058 1.1 38.8 -2.801 86 0.2.24.21 3735 structural constituent of ribosome F 9 119 240 7.6 49.6 9 119 240 7.6 49.6 4.065 87 0.2.27.2.0 16251 general RNA polymerase II transcription factor activity F 3 21 22 14.3 95.5 3 25 33 12 75.8 3.374 Cluster n°9 Index Path GOID GO Name GO Type Number Changed Local Number Measured Local Number in GO Local Percent Changed Local Percent Present Local Number Changed Number Measured Number in GO Percent Changed Percent Present Z Score PermuteP AdjustedP 1 0.0.2.0 7154 cell communication P 0 11 27 0 40.7 68 1708 3830 4 44.6 -5.358 2 0.0.2.0.0 7155 cell adhesion P 4 226 466 1.8 48.5 10 345 702 2.9 49.1 -2.965 3 0.0.2.0.0.2 16337 cell-cell adhesion P 0 15 29 0 51.7 3 131 313 2.3 41.9 -2.077 4 0.0.2.0.2 7267 cell-cell signaling P 4 187 288 2.1 64.9 7 346 542 2 63.8 -3.632 5 0.0.2.0.2.2 19226 transmission of nerve impulse P 0 1 1 0 100 3 163 257 1.8 63.4 -2.553 6 0.0.2.0.2.2.3 7268 synaptic transmission P 2 126 202 1.6 62.4 3 161 255 1.9 63.1 -2.525 7 0.0.2.0.7 7165 signal transduction P 23 547 954 4.2 57.3 58 1334 3088 4.3 43.2 -3.986 8 0.0.2.0.7.0 7166 cell surface receptor linked signal transduction P 2 83 133 2.4 62.4 16 536 1594 3 33.6 -3.667 9 0.0.2.0.7.0.3 7186 G-protein coupled receptor protein signaling pathway P 8 189 947 4.2 20 10 321 1245 3.1 25.8 -2.697 10 0.0.2.0.7.2.13 7264 small GTPase mediated signal transduction P 13 95 224 13.7 42.4 15 127 267 11.8 47.6 2.25 11 0.0.2.3 8151 cell growth and/or maintenance P 7 133 249 5.3 53.4 156 1909 3822 8.2 49.9 2.741 12 0.0.2.3.4 16043 cell organization and biogenesis P 0 0 0 0 0 35 306 631 11.4 48.5 3.274 13 0.0.2.3.4.5 7028 cytoplasm organization and biogenesis P 0 0 0 0 0 22 193 369 11.4 52.3 2.557 14 0.0.2.3.4.5.2 6996 organelle organization and biogenesis P 0 2 3 0 66.7 19 170 325 11.2 52.3 2.279 15 0.0.2.3.4.5.2.0.5.0 226 microtubule cytoskeleton organization and biogenesis P 1 5 13 20 38.5 4 23 49 17.4 46.9 2.013 16 0.0.2.3.4.5.2.2 7029 ER organization and biogenesis P 0 0 0 0 0 4 8 9 50 88.9 4.846 17 0.0.2.3.4.5.2.2.0 45047 protein-ER targeting P 0 0 0 0 0 4 8 9 50 88.9 4.846 18 0.0.2.3.4.5.2.2.0.0 6613 cotranslational membrane targeting P 3 6 7 50 85.7 3 6 7 50 85.7 4.196 19 0.0.2.3.4.5.2.6.5 6626 protein-mitochondrial targeting P 0 1 1 0 100 3 14 19 21.4 73.7 2.169 20 0.0.2.3.4.8 6997 nuclear organization and biogenesis P 0 2 3 0 66.7 11 86 226 12.8 38.1 2.208 21 0.0.2.3.4.8.0 7001 chromosome organization and biogenesis (sensu Eukarya) P 3 20 76 15 26.3 11 84 224 13.1 37.5 2.294 22 0.0.2.3.5.0 7049 cell cycle P 10 77 156 13 49.4 39 392 716 9.9 54.7 2.526 23 0.0.2.3.5.0.1 67 DNA replication and chromosome cycle P 0 5 6 0 83.3 15 112 225 13.4 49.8 2.78 24 0.0.2.3.5.0.1.1 30261 chromosome condensation P 0 0 0 0 0 4 12 13 33.3 92.3 3.645 25 0.0.2.3.5.0.1.2 7059 chromosome segregation P 2 9 13 22.2 69.2 4 15 21 26.7 71.4 3.051 26 0.0.2.3.5.0.1.3.3 6261 DNA dependent DNA replication P 1 8 8 12.5 100 7 46 80 15.2 57.5 2.265 27 0.0.2.3.5.0.3 279 M phase P 0 1 3 0 33.3 17 100 150 17 66.7 4.065 28 0.0.2.3.5.0.3.0 87 M phase of mitotic cell cycle P 1 2 3 50 66.7 16 78 114 20.5 68.4 4.822 29 0.0.2.3.5.0.3.0.1 7067 mitosis P 13 55 78 23.6 70.5 15 76 111 19.7 68.5 4.489 30 0.0.2.3.5.0.3.2 280 nuclear division P 0 0 0 0 0 16 96 141 16.7 68.1 3.851 31 0.0.2.3.5.0.3.2.1 7067 mitosis P 13 55 78 23.6 70.5 15 76 111 19.7 68.5 4.489 32 0.0.2.3.5.0.4 278 mitotic cell cycle P 0 0 0 0 0 30 196 354 15.3 55.4 4.777 33 0.0.2.3.5.0.4.4 87 M phase of mitotic cell cycle P 1 2 3 50 66.7 16 78 114 20.5 68.4 4.822 34 0.0.2.3.5.0.4.4.1 7067 mitosis P 13 55 78 23.6 70.5 15 76 111 19.7 68.5 4.489 35 0.0.2.3.5.0.4.8.0.3 6261 DNA dependent DNA replication P 1 8 8 12.5 100 7 46 80 15.2 57.5 2.265 36 0.0.2.3.5.1 910 cytokinesis P 8 46 94 17.4 48.9 8 47 95 17 49.5 2.782 37 0.0.2.3.10 6810 transport P 19 290 696 6.6 41.7 86 1009 2118 8.5 47.6 2.315 38 0.0.2.3.10.15 6818 hydrogen transport P 0 0 0 0 0 10 43 89 23.3 48.3 4.287 39 0.0.2.3.10.15.1 15992 proton transport P 9 39 82 23.1 47.6 10 42 88 23.8 47.7 4.379 40 0.0.2.3.10.16 46907 intracellular transport P 0 0 0 0 0 44 294 508 15 57.9 5.657 41 0.0.2.3.10.16.4.6 6892 post-Golgi transport P 2 8 8 25 100 3 10 13 30 76.9 2.909 42 0.0.2.3.10.16.8 6886 intracellular protein transport P 23 173 294 13.3 58.8 36 242 386 14.9 62.7 5.056 43 0.0.2.3.10.16.8.3 6605 protein targeting P 7 34 44 20.6 77.3 14 86 112 16.3 76.8 3.499 44 0.0.2.3.10.16.8.3.1 45047 protein-ER targeting P 0 0 0 0 0 4 8 9 50 88.9 4.846 45 0.0.2.3.10.16.8.3.1.0 6613 cotranslational membrane targeting P 3 6 7 50 85.7 3 6 7 50 85.7 4.196 46 0.0.2.3.10.16.8.3.4 6612 protein-membrane targeting P 1 2 2 50 100 4 8 9 50 88.9 4.846 47 0.0.2.3.10.16.8.3.4.0 6613 cotranslational membrane targeting P 3 6 7 50 85.7 3 6 7 50 85.7 4.196 48 0.0.2.3.10.16.8.3.5 6626 protein-mitochondrial targeting P 0 1 1 0 100 3 14 19 21.4 73.7 2.169 49 0.0.2.3.10.16.13 6913 nucleocytoplasmic transport P 1 1 1 100 100 7 46 65 15.2 70.8 2.265 50 0.0.2.3.10.17.3.1 30001 metal ion transport P 0 11 25 0 44 4 177 365 2.3 48.5 -2.439 51 0.0.2.3.10.17.3.2.1 15992 proton transport P 9 39 82 23.1 47.6 10 42 88 23.8 47.7 4.379 52 0.0.2.3.10.32 15031 protein transport P 2 18 36 11.1 50 38 258 421 14.7 61.3 5.131 53 0.0.2.3.10.32.2 6886 intracellular protein transport P 23 173 294 13.3 58.8 36 242 386 14.9 62.7 5.056 54 0.0.2.3.10.32.2.3 6605 protein targeting P 7 34 44 20.6 77.3 14 86 112 16.3 76.8 3.499 55 0.0.2.3.10.32.2.3.1 45047 protein-ER targeting P 0 0 0 0 0 4 8 9 50 88.9 4.846 56 0.0.2.3.10.32.2.3.1.0 6613 cotranslational membrane targeting P 3 6 7 50 85.7 3 6 7 50 85.7 4.196 57 0.0.2.3.10.32.2.3.4 6612 protein-membrane targeting P 1 2 2 50 100 4 8 9 50 88.9 4.846 58 0.0.2.3.10.32.2.3.4.0 6613 cotranslational membrane targeting P 3 6 7 50 85.7 3 6 7 50 85.7 4.196 59 0.0.2.3.10.32.2.3.5 6626 protein-mitochondrial targeting P 0 1 1 0 100 3 14 19 21.4 73.7 2.169 60 0.0.2.3.10.33 45045 secretory pathway P 0 1 2 0 50 11 63 105 17.5 60 3.363 61 0.0.2.3.10.33.3 6887 exocytosis P 1 12 25 8.3 48 4 22 43 18.2 51.2 2.116 62 0.0.2.3.10.33.3.1 16194 nonselective vesicle exocytosis P 0 0 0 0 0 3 7 14 42.9 50 3.783 63 0.0.2.3.10.33.5 6892 post-Golgi transport P 2 8 8 25 100 3 10 13 30 76.9 2.909 64 0.0.2.3.10.33.6 45047 protein-ER targeting P 0 0 0 0 0 4 8 9 50 88.9 4.846 65 0.0.2.3.10.33.6.0 6613 cotranslational membrane targeting P 3 6 7 50 85.7 3 6 7 50 85.7 4.196 66 0.0.2.3.10.36 16192 vesicle-mediated transport P 4 23 36 17.4 63.9 20 176 274 11.4 64.2 2.42 67 0.0.2.3.10.36.4 6887 exocytosis P 1 12 25 8.3 48 4 22 43 18.2 51.2 2.116 68 0.0.2.3.10.36.4.1 16194 nonselective vesicle exocytosis P 0 0 0 0 0 3 7 14 42.9 50 3.783 69 0.0.2.3.10.36.5.6 6892 post-Golgi transport P 2 8 8 25 100 3 10 13 30 76.9 2.909 70 0.0.2.3.10.36.6 6899 nonselective vesicle transport P 7 48 61 14.6 78.7 7 48 61 14.6 78.7 2.14 71 0.0.3 7275 development P 7 284 503 2.5 56.5 30 916 1531 3.3 59.8 -4.568 72 0.0.3.12 9653 morphogenesis P 0 1 3 0 33.3 17 527 804 3.2 65.5 -3.406 73 0.0.3.12.8 9887 organogenesis P 0 0 1 0 0 14 503 769 2.8 65.4 -3.73 74 0.0.3.12.8.19 7399 neurogenesis P 3 149 223 2 66.8 6 239 363 2.5 65.8 -2.69 75 0.0.5.3 8151 cell growth and/or maintenance P 7 133 249 5.3 53.4 156 1909 3822 8.2 49.9 2.741 76 0.0.5.3.4 16043 cell organization and biogenesis P 0 0 0 0 0 35 306 631 11.4 48.5 3.274 77 0.0.5.3.4.5 7028 cytoplasm organization and biogenesis P 0 0 0 0 0 22 193 369 11.4 52.3 2.557 78 0.0.5.3.4.5.2 6996 organelle organization and biogenesis P 0 2 3 0 66.7 19 170 325 11.2 52.3 2.279 79 0.0.5.3.4.5.2.0.5.0 226 microtubule cytoskeleton organization and biogenesis P 1 5 13 20 38.5 4 23 49 17.4 46.9 2.013 80 0.0.5.3.4.5.2.2 7029 ER organization and biogenesis P 0 0 0 0 0 4 8 9 50 88.9 4.846 81 0.0.5.3.4.5.2.2.0 45047 protein-ER targeting P 0 0 0 0 0 4 8 9 50 88.9 4.846 82 0.0.5.3.4.5.2.2.0.0 6613 cotranslational membrane targeting P 3 6 7 50 85.7 3 6 7 50 85.7 4.196 83 0.0.5.3.4.5.2.6.5 6626 protein-mitochondrial targeting P 0 1 1 0 100 3 14 19 21.4 73.7 2.169 84 0.0.5.3.4.8 6997 nuclear organization and biogenesis P 0 2 3 0 66.7 11 86 226 12.8 38.1 2.208 85 0.0.5.3.4.8.0 7001 chromosome organization and biogenesis (sensu Eukarya) P 3 20 76 15 26.3 11 84 224 13.1 37.5 2.294 86 0.0.5.3.5.0 7049 cell cycle P 10 77 156 13 49.4 39 392 716 9.9 54.7 2.526 87 0.0.5.3.5.0.1 67 DNA replication and chromosome cycle P 0 5 6 0 83.3 15 112 225 13.4 49.8 2.78 88 0.0.5.3.5.0.1.1 30261 chromosome condensation P 0 0 0 0 0 4 12 13 33.3 92.3 3.645 89 0.0.5.3.5.0.1.2 7059 chromosome segregation P 2 9 13 22.2 69.2 4 15 21 26.7 71.4 3.051 90 0.0.5.3.5.0.1.3.3 6261 DNA dependent DNA replication P 1 8 8 12.5 100 7 46 80 15.2 57.5 2.265 91 0.0.5.3.5.0.3 279 M phase P 0 1 3 0 33.3 17 100 150 17 66.7 4.065 92 0.0.5.3.5.0.3.0 87 M phase of mitotic cell cycle P 1 2 3 50 66.7 16 78 114 20.5 68.4 4.822 93 0.0.5.3.5.0.3.0.1 7067 mitosis P 13 55 78 23.6 70.5 15 76 111 19.7 68.5 4.489 94 0.0.5.3.5.0.3.2 280 nuclear division P 0 0 0 0 0 16 96 141 16.7 68.1 3.851 95 0.0.5.3.5.0.3.2.1 7067 mitosis P 13 55 78 23.6 70.5 15 76 111 19.7 68.5 4.489 96 0.0.5.3.5.0.4 278 mitotic cell cycle P 0 0 0 0 0 30 196 354 15.3 55.4 4.777 97 0.0.5.3.5.0.4.4 87 M phase of mitotic cell cycle P 1 2 3 50 66.7 16 78 114 20.5 68.4 4.822 98 0.0.5.3.5.0.4.4.1 7067 mitosis P 13 55 78 23.6 70.5 15 76 111 19.7 68.5 4.489 99 0.0.5.3.5.0.4.8.0.3 6261 DNA dependent DNA replication P 1 8 8 12.5 100 7 46 80 15.2 57.5 2.265 100 0.0.5.3.5.1 910 cytokinesis P 8 46 94 17.4 48.9 8 47 95 17 49.5 2.782 101 0.0.5.3.10 6810 transport P 19 290 696 6.6 41.7 86 1009 2118 8.5 47.6 2.315 102 0.0.5.3.10.15 6818 hydrogen transport P 0 0 0 0 0 10 43 89 23.3 48.3 4.287 103 0.0.5.3.10.15.1 15992 proton transport P 9 39 82 23.1 47.6 10 42 88 23.8 47.7 4.379 104 0.0.5.3.10.16 46907 intracellular transport P 0 0 0 0 0 44 294 508 15 57.9 5.657 105 0.0.5.3.10.16.4.6 6892 post-Golgi transport P 2 8 8 25 100 3 10 13 30 76.9 2.909 106 0.0.5.3.10.16.8 6886 intracellular protein transport P 23 173 294 13.3 58.8 36 242 386 14.9 62.7 5.056 107 0.0.5.3.10.16.8.3 6605 protein targeting P 7 34 44 20.6 77.3 14 86 112 16.3 76.8 3.499 108 0.0.5.3.10.16.8.3.1 45047 protein-ER targeting P 0 0 0 0 0 4 8 9 50 88.9 4.846 109 0.0.5.3.10.16.8.3.1.0 6613 cotranslational membrane targeting P 3 6 7 50 85.7 3 6 7 50 85.7 4.196 110 0.0.5.3.10.16.8.3.4 6612 protein-membrane targeting P 1 2 2 50 100 4 8 9 50 88.9 4.846 111 0.0.5.3.10.16.8.3.4.0 6613 cotranslational membrane targeting P 3 6 7 50 85.7 3 6 7 50 85.7 4.196 112 0.0.5.3.10.16.8.3.5 6626 protein-mitochondrial targeting P 0 1 1 0 100 3 14 19 21.4 73.7 2.169 113 0.0.5.3.10.16.13 6913 nucleocytoplasmic transport P 1 1 1 100 100 7 46 65 15.2 70.8 2.265 114 0.0.5.3.10.17.3.1 30001 metal ion transport P 0 11 25 0 44 4 177 365 2.3 48.5 -2.439 115 0.0.5.3.10.17.3.2.1 15992 proton transport P 9 39 82 23.1 47.6 10 42 88 23.8 47.7 4.379 116 0.0.5.3.10.32 15031 protein transport P 2 18 36 11.1 50 38 258 421 14.7 61.3 5.131 117 0.0.5.3.10.32.2 6886 intracellular protein transport P 23 173 294 13.3 58.8 36 242 386 14.9 62.7 5.056 118 0.0.5.3.10.32.2.3 6605 protein targeting P 7 34 44 20.6 77.3 14 86 112 16.3 76.8 3.499 119 0.0.5.3.10.32.2.3.1 45047 protein-ER targeting P 0 0 0 0 0 4 8 9 50 88.9 4.846 120 0.0.5.3.10.32.2.3.1.0 6613 cotranslational membrane targeting P 3 6 7 50 85.7 3 6 7 50 85.7 4.196 121 0.0.5.3.10.32.2.3.4 6612 protein-membrane targeting P 1 2 2 50 100 4 8 9 50 88.9 4.846 122 0.0.5.3.10.32.2.3.4.0 6613 cotranslational membrane targeting P 3 6 7 50 85.7 3 6 7 50 85.7 4.196 123 0.0.5.3.10.32.2.3.5 6626 protein-mitochondrial targeting P 0 1 1 0 100 3 14 19 21.4 73.7 2.169 124 0.0.5.3.10.33 45045 secretory pathway P 0 1 2 0 50 11 63 105 17.5 60 3.363 125 0.0.5.3.10.33.3 6887 exocytosis P 1 12 25 8.3 48 4 22 43 18.2 51.2 2.116 126 0.0.5.3.10.33.3.1 16194 nonselective vesicle exocytosis P 0 0 0 0 0 3 7 14 42.9 50 3.783 127 0.0.5.3.10.33.5 6892 post-Golgi transport P 2 8 8 25 100 3 10 13 30 76.9 2.909 128 0.0.5.3.10.33.6 45047 protein-ER targeting P 0 0 0 0 0 4 8 9 50 88.9 4.846 129 0.0.5.3.10.33.6.0 6613 cotranslational membrane targeting P 3 6 7 50 85.7 3 6 7 50 85.7 4.196 130 0.0.5.3.10.36 16192 vesicle-mediated transport P 4 23 36 17.4 63.9 20 176 274 11.4 64.2 2.42 131 0.0.5.3.10.36.4 6887 exocytosis P 1 12 25 8.3 48 4 22 43 18.2 51.2 2.116 132 0.0.5.3.10.36.4.1 16194 nonselective vesicle exocytosis P 0 0 0 0 0 3 7 14 42.9 50 3.783 133 0.0.5.3.10.36.5.6 6892 post-Golgi transport P 2 8 8 25 100 3 10 13 30 76.9 2.909 134 0.0.5.3.10.36.6 6899 nonselective vesicle transport P 7 48 61 14.6 78.7 7 48 61 14.6 78.7 2.14 135 0.0.5.20 8152 metabolism P 13 185 456 7 40.6 270 3523 7651 7.7 46 2.81 136 0.0.5.20.0.3 46164 alcohol catabolism P 0 0 0 0 0 8 37 69 21.6 53.6 3.579 137 0.0.5.20.0.3.8 46365 monosaccharide catabolism P 0 0 0 0 0 8 37 69 21.6 53.6 3.579 138 0.0.5.20.0.3.8.0 19320 hexose catabolism P 0 0 0 0 0 7 36 68 19.4 52.9 3.011 139 0.0.5.20.0.3.8.0.4 6007 glucose catabolism P 0 2 2 0 100 7 35 67 20 52.2 3.099 140 0.0.5.20.0.3.8.0.4.0 6096 glycolysis P 7 29 55 24.1 52.7 7 29 55 24.1 52.7 3.705 141 0.0.5.20.0.11.0.4 6006 glucose metabolism P 1 10 13 10 76.9 7 50 90 14 55.6 2.02 142 0.0.5.20.0.11.0.4.3 6007 glucose catabolism P 0 2 2 0 100 7 35 67 20 52.2 3.099 143 0.0.5.20.0.11.0.4.3.0 6096 glycolysis P 7 29 55 24.1 52.7 7 29 55 24.1 52.7 3.705 144 0.0.5.20.0.11.0.6 19320 hexose catabolism P 0 0 0 0 0 7 36 68 19.4 52.9 3.011 145 0.0.5.20.0.11.0.6.4 6007 glucose catabolism P 0 2 2 0 100 7 35 67 20 52.2 3.099 146 0.0.5.20.0.11.0.6.4.0 6096 glycolysis P 7 29 55 24.1 52.7 7 29 55 24.1 52.7 3.705 147 0.0.5.20.0.11.2 46365 monosaccharide catabolism P 0 0 0 0 0 8 37 69 21.6 53.6 3.579 148 0.0.5.20.0.11.2.0 19320 hexose catabolism P 0 0 0 0 0 7 36 68 19.4 52.9 3.011 149 0.0.5.20.0.11.2.0.4 6007 glucose catabolism P 0 2 2 0 100 7 35 67 20 52.2 3.099 150 0.0.5.20.0.11.2.0.4.0 6096 glycolysis P 7 29 55 24.1 52.7 7 29 55 24.1 52.7 3.705 151 0.0.5.20.0.16.0.0 6695 cholesterol biosynthesis P 4 14 17 28.6 82.4 4 15 20 26.7 75 3.051 152 0.0.5.20.0.16.3 16126 sterol biosynthesis P 0 3 4 0 75 4 18 27 22.2 66.7 2.594 153 0.0.5.20.0.16.3.0 6695 cholesterol biosynthesis P 4 14 17 28.6 82.4 4 15 20 26.7 75 3.051 154 0.0.5.20.2.7 9309 amine biosynthesis P 0 1 1 0 100 6 39 68 15.4 57.4 2.126 155 0.0.5.20.2.7.2 42401 biogenic amine biosynthesis P 0 0 0 0 0 3 14 20 21.4 70 2.169 156 0.0.5.20.2.7.2.12 6596 polyamine biosynthesis P 3 3 4 100 75 3 6 7 50 85.7 4.196 157 0.0.5.20.2.15.1 42401 biogenic amine biosynthesis P 0 0 0 0 0 3 14 20 21.4 70 2.169 158 0.0.5.20.2.15.1.12 6596 polyamine biosynthesis P 3 3 4 100 75 3 6 7 50 85.7 4.196 159 0.0.5.20.2.15.11 6595 polyamine metabolism P 0 1 2 0 50 3 7 9 42.9 77.8 3.783 160 0.0.5.20.2.15.11.0 6596 polyamine biosynthesis P 3 3 4 100 75 3 6 7 50 85.7 4.196 161 0.0.5.20.3.0.4.5 42401 biogenic amine biosynthesis P 0 0 0 0 0 3 14 20 21.4 70 2.169 162 0.0.5.20.3.0.4.5.12 6596 polyamine biosynthesis P 3 3 4 100 75 3 6 7 50 85.7 4.196 163 0.0.5.20.3.0.7.1 42401 biogenic amine biosynthesis P 0 0 0 0 0 3 14 20 21.4 70 2.169 164 0.0.5.20.3.0.7.1.12 6596 polyamine biosynthesis P 3 3 4 100 75 3 6 7 50 85.7 4.196 165 0.0.5.20.3.0.7.11 6595 polyamine metabolism P 0 1 2 0 50 3 7 9 42.9 77.8 3.783 166 0.0.5.20.3.0.7.11.0 6596 polyamine biosynthesis P 3 3 4 100 75 3 6 7 50 85.7 4.196 167 0.0.5.20.5 9058 biosynthesis P 2 24 66 8.3 36.4 76 603 1112 12.6 54.2 5.889 168 0.0.5.20.5.4 9309 amine biosynthesis P 0 1 1 0 100 6 39 68 15.4 57.4 2.126 169 0.0.5.20.5.4.2 42401 biogenic amine biosynthesis P 0 0 0 0 0 3 14 20 21.4 70 2.169 170 0.0.5.20.5.4.2.12 6596 polyamine biosynthesis P 3 3 4 100 75 3 6 7 50 85.7 4.196 171 0.0.5.20.5.5.5 42401 biogenic amine biosynthesis P 0 0 0 0 0 3 14 20 21.4 70 2.169 172 0.0.5.20.5.5.5.12 6596 polyamine biosynthesis P 3 3 4 100 75 3 6 7 50 85.7 4.196 173 0.0.5.20.5.12 46138 coenzymes and prosthetic group biosynthesis P 0 0 0 0 0 7 44 89 15.9 49.4 2.398 174 0.0.5.20.5.12.0 9108 coenzyme biosynthesis P 0 0 2 0 0 7 35 73 20 47.9 3.099 175 0.0.5.20.5.12.0.3 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 176 0.0.5.20.5.21 8610 lipid biosynthesis P 1 6 6 16.7 100 13 109 168 11.9 64.9 2.13 177 0.0.5.20.5.21.0 6633 fatty acid biosynthesis P 4 15 27 26.7 55.6 5 28 44 17.9 63.6 2.32 178 0.0.5.20.5.21.8.8 16126 sterol biosynthesis P 0 3 4 0 75 4 18 27 22.2 66.7 2.594 179 0.0.5.20.5.21.8.8.0 6695 cholesterol biosynthesis P 4 14 17 28.6 82.4 4 15 20 26.7 75 3.051 180 0.0.5.20.5.22 9059 macromolecule biosynthesis P 0 0 0 0 0 43 316 597 13.6 52.9 4.895 181 0.0.5.20.5.22.3 6412 protein biosynthesis P 20 132 243 15.2 54.3 43 316 597 13.6 52.9 4.895 182 0.0.5.20.5.22.3.1 6418 amino acid activation P 2 5 24 40 20.8 6 25 75 24 33.3 3.412 183 0.0.5.20.5.22.3.11 42158 lipoprotein biosynthesis P 0 0 0 0 0 3 10 19 30 52.6 2.909 184 0.0.5.20.5.22.3.11.0 6497 protein lipidation P 0 0 0 0 0 3 10 19 30 52.6 2.909 185 0.0.5.20.5.22.3.18 6417 regulation of protein biosynthesis P 3 12 18 25 66.7 3 13 21 23.1 61.9 2.326 186 0.0.5.20.5.22.3.19 6445 regulation of translation P 0 12 21 0 57.1 7 41 66 17.1 62.1 2.61 187 0.0.5.20.5.22.3.19.7 6446 regulation of translational initiation P 7 22 33 31.8 66.7 7 23 34 30.4 67.6 4.498 188 0.0.5.20.5.22.3.29 6413 translational initiation P 2 17 31 11.8 54.8 9 40 64 22.5 62.5 3.943 189 0.0.5.20.5.22.3.29.3 6446 regulation of translational initiation P 7 22 33 31.8 66.7 7 23 34 30.4 67.6 4.498 190 0.0.5.20.5.27 9165 nucleotide biosynthesis P 0 6 12 0 50 10 54 102 18.5 52.9 3.422 191 0.0.5.20.5.27.4 9142 nucleoside triphosphate biosynthesis P 1 2 3 50 66.7 9 26 44 34.6 59.1 5.63 192 0.0.5.20.5.27.4.1 9145 purine nucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 193 0.0.5.20.5.27.4.1.1 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 194 0.0.5.20.5.27.4.1.1.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 195 0.0.5.20.5.27.4.1.1.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 196 0.0.5.20.5.27.4.3 9201 ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 197 0.0.5.20.5.27.4.3.0 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 198 0.0.5.20.5.27.4.3.0.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 199 0.0.5.20.5.27.4.3.0.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 200 0.0.5.20.5.27.5 6164 purine nucleotide biosynthesis P 0 3 10 0 30 9 34 61 26.5 55.7 4.554 201 0.0.5.20.5.27.5.3 9145 purine nucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 202 0.0.5.20.5.27.5.3.1 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 203 0.0.5.20.5.27.5.3.1.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 204 0.0.5.20.5.27.5.3.1.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 205 0.0.5.20.5.27.5.4 9152 purine ribonucleotide biosynthesis P 0 1 1 0 100 9 31 57 29 54.4 4.915 206 0.0.5.20.5.27.5.4.2 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 207 0.0.5.20.5.27.5.4.2.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 208 0.0.5.20.5.27.5.4.2.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 209 0.0.5.20.5.27.6 6221 pyrimidine nucleotide biosynthesis P 1 2 6 50 33.3 3 12 23 25 52.2 2.499 210 0.0.5.20.5.27.6.4 9220 pyrimidine ribonucleotide biosynthesis P 0 1 1 0 100 3 10 14 30 71.4 2.909 211 0.0.5.20.5.27.8 9260 ribonucleotide biosynthesis P 0 0 0 0 0 10 35 63 28.6 55.6 5.115 212 0.0.5.20.5.27.8.0 9152 purine ribonucleotide biosynthesis P 0 1 1 0 100 9 31 57 29 54.4 4.915 213 0.0.5.20.5.27.8.0.2 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 214 0.0.5.20.5.27.8.0.2.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 215 0.0.5.20.5.27.8.0.2.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 216 0.0.5.20.5.27.8.1 9220 pyrimidine ribonucleotide biosynthesis P 0 1 1 0 100 3 10 14 30 71.4 2.909 217 0.0.5.20.5.27.8.4 9201 ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 218 0.0.5.20.5.27.8.4.0 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 219 0.0.5.20.5.27.8.4.0.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 220 0.0.5.20.5.27.8.4.0.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 221 0.0.5.20.5.30.0.7 6633 fatty acid biosynthesis P 4 15 27 26.7 55.6 5 28 44 17.9 63.6 2.32 222 0.0.5.20.5.35.18 6417 regulation of protein biosynthesis P 3 12 18 25 66.7 3 13 21 23.1 61.9 2.326 223 0.0.5.20.6.6 16052 carbohydrate catabolism P 0 0 0 0 0 10 47 87 21.3 54 3.943 224 0.0.5.20.6.6.7 46365 monosaccharide catabolism P 0 0 0 0 0 8 37 69 21.6 53.6 3.579 225 0.0.5.20.6.6.7.0 19320 hexose catabolism P 0 0 0 0 0 7 36 68 19.4 52.9 3.011 226 0.0.5.20.6.6.7.0.4 6007 glucose catabolism P 0 2 2 0 100 7 35 67 20 52.2 3.099 227 0.0.5.20.6.6.7.0.4.0 6096 glycolysis P 7 29 55 24.1 52.7 7 29 55 24.1 52.7 3.705 228 0.0.5.20.6.12 6092 main pathways of carbohydrate metabolism P 0 0 2 0 0 11 58 108 19 53.7 3.683 229 0.0.5.20.6.12.2 6096 glycolysis P 7 29 55 24.1 52.7 7 29 55 24.1 52.7 3.705 230 0.0.5.20.6.12.6 6099 tricarboxylic acid cycle P 4 17 29 23.5 58.6 4 17 29 23.5 58.6 2.735 231 0.0.5.20.6.13.0.4 6006 glucose metabolism P 1 10 13 10 76.9 7 50 90 14 55.6 2.02 232 0.0.5.20.6.13.0.4.3 6007 glucose catabolism P 0 2 2 0 100 7 35 67 20 52.2 3.099 233 0.0.5.20.6.13.0.4.3.0 6096 glycolysis P 7 29 55 24.1 52.7 7 29 55 24.1 52.7 3.705 234 0.0.5.20.6.13.0.6 19320 hexose catabolism P 0 0 0 0 0 7 36 68 19.4 52.9 3.011 235 0.0.5.20.6.13.0.6.4 6007 glucose catabolism P 0 2 2 0 100 7 35 67 20 52.2 3.099 236 0.0.5.20.6.13.0.6.4.0 6096 glycolysis P 7 29 55 24.1 52.7 7 29 55 24.1 52.7 3.705 237 0.0.5.20.6.13.2 46365 monosaccharide catabolism P 0 0 0 0 0 8 37 69 21.6 53.6 3.579 238 0.0.5.20.6.13.2.0 19320 hexose catabolism P 0 0 0 0 0 7 36 68 19.4 52.9 3.011 239 0.0.5.20.6.13.2.0.4 6007 glucose catabolism P 0 2 2 0 100 7 35 67 20 52.2 3.099 240 0.0.5.20.6.13.2.0.4.0 6096 glycolysis P 7 29 55 24.1 52.7 7 29 55 24.1 52.7 3.705 241 0.0.5.20.6.18.7 6073 glucan metabolism P 0 0 0 0 0 4 22 27 18.2 81.5 2.116 242 0.0.5.20.6.18.7.6 5977 glycogen metabolism P 2 10 12 20 83.3 4 22 26 18.2 84.6 2.116 243 0.0.5.20.8.0 46164 alcohol catabolism P 0 0 0 0 0 8 37 69 21.6 53.6 3.579 244 0.0.5.20.8.0.8 46365 monosaccharide catabolism P 0 0 0 0 0 8 37 69 21.6 53.6 3.579 245 0.0.5.20.8.0.8.0 19320 hexose catabolism P 0 0 0 0 0 7 36 68 19.4 52.9 3.011 246 0.0.5.20.8.0.8.0.4 6007 glucose catabolism P 0 2 2 0 100 7 35 67 20 52.2 3.099 247 0.0.5.20.8.0.8.0.4.0 6096 glycolysis P 7 29 55 24.1 52.7 7 29 55 24.1 52.7 3.705 248 0.0.5.20.8.8 16052 carbohydrate catabolism P 0 0 0 0 0 10 47 87 21.3 54 3.943 249 0.0.5.20.8.8.7 46365 monosaccharide catabolism P 0 0 0 0 0 8 37 69 21.6 53.6 3.579 250 0.0.5.20.8.8.7.0 19320 hexose catabolism P 0 0 0 0 0 7 36 68 19.4 52.9 3.011 251 0.0.5.20.8.8.7.0.4 6007 glucose catabolism P 0 2 2 0 100 7 35 67 20 52.2 3.099 252 0.0.5.20.8.8.7.0.4.0 6096 glycolysis P 7 29 55 24.1 52.7 7 29 55 24.1 52.7 3.705 253 0.0.5.20.8.22.1.3.9 19941 modification-dependent protein catabolism P 0 0 0 0 0 12 69 143 17.4 48.3 3.499 254 0.0.5.20.8.22.1.3.9.3 6511 ubiquitin-dependent protein catabolism P 11 67 140 16.4 47.9 12 69 143 17.4 48.3 3.499 255 0.0.5.20.9 6731 coenzymes and prosthetic group metabolism P 0 0 0 0 0 11 67 129 16.4 51.9 3.13 256 0.0.5.20.9.0 6732 coenzyme metabolism P 0 0 0 0 0 10 55 110 18.2 50 3.354 257 0.0.5.20.9.0.3 46034 ATP metabolism P 1 3 4 33.3 75 8 21 34 38.1 61.8 5.692 258 0.0.5.20.9.0.3.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 259 0.0.5.20.9.0.6 9108 coenzyme biosynthesis P 0 0 2 0 0 7 35 73 20 47.9 3.099 260 0.0.5.20.9.0.6.3 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 261 0.0.5.20.9.0.12 6752 group transfer coenzyme metabolism P 0 0 0 0 0 8 27 43 29.6 62.8 4.709 262 0.0.5.20.9.0.12.2 6753 nucleoside phosphate metabolism P 0 0 0 0 0 6 17 29 35.3 58.6 4.661 263 0.0.5.20.9.0.12.2.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 264 0.0.5.20.9.1 46138 coenzymes and prosthetic group biosynthesis P 0 0 0 0 0 7 44 89 15.9 49.4 2.398 265 0.0.5.20.9.1.0 9108 coenzyme biosynthesis P 0 0 2 0 0 7 35 73 20 47.9 3.099 266 0.0.5.20.9.1.0.3 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 267 0.0.5.20.11 6118 electron transport P 19 187 511 10.2 36.6 23 201 545 11.4 36.9 2.636 268 0.0.5.20.11.5 42773 ATP synthesis coupled electron transport P 0 0 0 0 0 4 14 43 28.6 32.6 3.23 269 0.0.5.20.11.5.1 42775 ATP synthesis coupled electron transport (sensu Eukarya) P 0 0 0 0 0 4 14 43 28.6 32.6 3.23 270 0.0.5.20.11.5.1.1 6120 "mitochondrial electron transport\, NADH to ubiquinone" P 4 14 36 28.6 38.9 4 14 36 28.6 38.9 3.23 271 0.0.5.20.11.15 6129 protein-disulfide reduction P 0 1 1 0 100 4 15 44 26.7 34.1 3.051 272 0.0.5.20.11.15.0 42773 ATP synthesis coupled electron transport P 0 0 0 0 0 4 14 43 28.6 32.6 3.23 273 0.0.5.20.11.15.0.1 42775 ATP synthesis coupled electron transport (sensu Eukarya) P 0 0 0 0 0 4 14 43 28.6 32.6 3.23 274 0.0.5.20.11.15.0.1.1 6120 "mitochondrial electron transport\, NADH to ubiquinone" P 4 14 36 28.6 38.9 4 14 36 28.6 38.9 3.23 275 0.0.5.20.12 6091 energy pathways P 9 73 89 12.3 82 23 151 225 15.2 67.1 4.143 276 0.0.5.20.12.0 15980 energy derivation by oxidation of organic compounds P 0 3 3 0 100 16 91 151 17.6 60.3 4.097 277 0.0.5.20.12.0.0 45333 cellular respiration P 0 0 1 0 0 3 6 10 50 60 4.196 278 0.0.5.20.12.0.0.0 9060 aerobic respiration P 3 6 9 50 66.7 3 6 9 50 66.7 4.196 279 0.0.5.20.12.0.1.0 5977 glycogen metabolism P 2 10 12 20 83.3 4 22 26 18.2 84.6 2.116 280 0.0.5.20.12.0.3 6092 main pathways of carbohydrate metabolism P 0 0 2 0 0 11 58 108 19 53.7 3.683 281 0.0.5.20.12.0.3.2 6096 glycolysis P 7 29 55 24.1 52.7 7 29 55 24.1 52.7 3.705 282 0.0.5.20.12.0.3.6 6099 tricarboxylic acid cycle P 4 17 29 23.5 58.6 4 17 29 23.5 58.6 2.735 283 0.0.5.20.20.0.2 6633 fatty acid biosynthesis P 4 15 27 26.7 55.6 5 28 44 17.9 63.6 2.32 284 0.0.5.20.20.4 8610 lipid biosynthesis P 1 6 6 16.7 100 13 109 168 11.9 64.9 2.13 285 0.0.5.20.20.4.0 6633 fatty acid biosynthesis P 4 15 27 26.7 55.6 5 28 44 17.9 63.6 2.32 286 0.0.5.20.20.4.8.8 16126 sterol biosynthesis P 0 3 4 0 75 4 18 27 22.2 66.7 2.594 287 0.0.5.20.20.4.8.8.0 6695 cholesterol biosynthesis P 4 14 17 28.6 82.4 4 15 20 26.7 75 3.051 288 0.0.5.20.20.13.9.8 16126 sterol biosynthesis P 0 3 4 0 75 4 18 27 22.2 66.7 2.594 289 0.0.5.20.20.13.9.8.0 6695 cholesterol biosynthesis P 4 14 17 28.6 82.4 4 15 20 26.7 75 3.051 290 0.0.5.20.20.13.11.0.0 6695 cholesterol biosynthesis P 4 14 17 28.6 82.4 4 15 20 26.7 75 3.051 291 0.0.5.20.20.13.11.3 16126 sterol biosynthesis P 0 3 4 0 75 4 18 27 22.2 66.7 2.594 292 0.0.5.20.20.13.11.3.0 6695 cholesterol biosynthesis P 4 14 17 28.6 82.4 4 15 20 26.7 75 3.051 293 0.0.5.20.25.0 6259 DNA metabolism P 0 16 23 0 69.6 31 280 614 11.1 45.6 2.877 294 0.0.5.20.25.0.7 6281 DNA repair P 8 73 116 11 62.9 16 114 204 14 55.9 3.079 295 0.0.5.20.25.0.7.11 6289 nucleotide-excision repair P 3 10 20 30 50 3 14 25 21.4 56 2.169 296 0.0.5.20.25.0.8.3 6261 DNA dependent DNA replication P 1 8 8 12.5 100 7 46 80 15.2 57.5 2.265 297 0.0.5.20.25.6 9117 nucleotide metabolism P 0 8 15 0 53.3 12 72 141 16.7 51.1 3.33 298 0.0.5.20.25.6.6 9141 nucleoside triphosphate metabolism P 0 0 0 0 0 11 31 54 35.5 57.4 6.342 299 0.0.5.20.25.6.6.1 9142 nucleoside triphosphate biosynthesis P 1 2 3 50 66.7 9 26 44 34.6 59.1 5.63 300 0.0.5.20.25.6.6.1.1 9145 purine nucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 301 0.0.5.20.25.6.6.1.1.1 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 302 0.0.5.20.25.6.6.1.1.1.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 303 0.0.5.20.25.6.6.1.1.1.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 304 0.0.5.20.25.6.6.1.3 9201 ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 305 0.0.5.20.25.6.6.1.3.0 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 306 0.0.5.20.25.6.6.1.3.0.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 307 0.0.5.20.25.6.6.1.3.0.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 308 0.0.5.20.25.6.6.3 9144 purine nucleoside triphosphate metabolism P 0 0 0 0 0 11 30 48 36.7 62.5 6.496 309 0.0.5.20.25.6.6.3.1 9145 purine nucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 310 0.0.5.20.25.6.6.3.1.1 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 311 0.0.5.20.25.6.6.3.1.1.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 312 0.0.5.20.25.6.6.3.1.1.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 313 0.0.5.20.25.6.6.3.3 9205 purine ribonucleoside triphosphate metabolism P 0 0 0 0 0 11 30 48 36.7 62.5 6.496 314 0.0.5.20.25.6.6.3.3.0 46034 ATP metabolism P 1 3 4 33.3 75 8 21 34 38.1 61.8 5.692 315 0.0.5.20.25.6.6.3.3.0.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 316 0.0.5.20.25.6.6.3.3.1 46039 GTP metabolism P 0 0 0 0 0 3 9 14 33.3 64.3 3.156 317 0.0.5.20.25.6.6.3.3.1.0 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 318 0.0.5.20.25.6.6.3.3.3 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 319 0.0.5.20.25.6.6.3.3.3.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 320 0.0.5.20.25.6.6.3.3.3.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 321 0.0.5.20.25.6.6.5 9199 ribonucleoside triphosphate metabolism P 0 0 0 0 0 11 30 48 36.7 62.5 6.496 322 0.0.5.20.25.6.6.5.0 9205 purine ribonucleoside triphosphate metabolism P 0 0 0 0 0 11 30 48 36.7 62.5 6.496 323 0.0.5.20.25.6.6.5.0.0 46034 ATP metabolism P 1 3 4 33.3 75 8 21 34 38.1 61.8 5.692 324 0.0.5.20.25.6.6.5.0.0.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 325 0.0.5.20.25.6.6.5.0.1 46039 GTP metabolism P 0 0 0 0 0 3 9 14 33.3 64.3 3.156 326 0.0.5.20.25.6.6.5.0.1.0 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 327 0.0.5.20.25.6.6.5.0.3 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 328 0.0.5.20.25.6.6.5.0.3.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 329 0.0.5.20.25.6.6.5.0.3.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 330 0.0.5.20.25.6.6.5.2 9201 ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 331 0.0.5.20.25.6.6.5.2.0 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 332 0.0.5.20.25.6.6.5.2.0.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 333 0.0.5.20.25.6.6.5.2.0.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 334 0.0.5.20.25.6.7 9165 nucleotide biosynthesis P 0 6 12 0 50 10 54 102 18.5 52.9 3.422 335 0.0.5.20.25.6.7.4 9142 nucleoside triphosphate biosynthesis P 1 2 3 50 66.7 9 26 44 34.6 59.1 5.63 336 0.0.5.20.25.6.7.4.1 9145 purine nucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 337 0.0.5.20.25.6.7.4.1.1 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 338 0.0.5.20.25.6.7.4.1.1.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 339 0.0.5.20.25.6.7.4.1.1.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 340 0.0.5.20.25.6.7.4.3 9201 ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 341 0.0.5.20.25.6.7.4.3.0 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 342 0.0.5.20.25.6.7.4.3.0.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 343 0.0.5.20.25.6.7.4.3.0.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 344 0.0.5.20.25.6.7.5 6164 purine nucleotide biosynthesis P 0 3 10 0 30 9 34 61 26.5 55.7 4.554 345 0.0.5.20.25.6.7.5.3 9145 purine nucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 346 0.0.5.20.25.6.7.5.3.1 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 347 0.0.5.20.25.6.7.5.3.1.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 348 0.0.5.20.25.6.7.5.3.1.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 349 0.0.5.20.25.6.7.5.4 9152 purine ribonucleotide biosynthesis P 0 1 1 0 100 9 31 57 29 54.4 4.915 350 0.0.5.20.25.6.7.5.4.2 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 351 0.0.5.20.25.6.7.5.4.2.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 352 0.0.5.20.25.6.7.5.4.2.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 353 0.0.5.20.25.6.7.6 6221 pyrimidine nucleotide biosynthesis P 1 2 6 50 33.3 3 12 23 25 52.2 2.499 354 0.0.5.20.25.6.7.6.4 9220 pyrimidine ribonucleotide biosynthesis P 0 1 1 0 100 3 10 14 30 71.4 2.909 355 0.0.5.20.25.6.7.8 9260 ribonucleotide biosynthesis P 0 0 0 0 0 10 35 63 28.6 55.6 5.115 356 0.0.5.20.25.6.7.8.0 9152 purine ribonucleotide biosynthesis P 0 1 1 0 100 9 31 57 29 54.4 4.915 357 0.0.5.20.25.6.7.8.0.2 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 358 0.0.5.20.25.6.7.8.0.2.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 359 0.0.5.20.25.6.7.8.0.2.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 360 0.0.5.20.25.6.7.8.1 9220 pyrimidine ribonucleotide biosynthesis P 0 1 1 0 100 3 10 14 30 71.4 2.909 361 0.0.5.20.25.6.7.8.4 9201 ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 362 0.0.5.20.25.6.7.8.4.0 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 363 0.0.5.20.25.6.7.8.4.0.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 364 0.0.5.20.25.6.7.8.4.0.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 365 0.0.5.20.25.6.10 6163 purine nucleotide metabolism P 0 1 1 0 100 11 40 69 27.5 58 5.201 366 0.0.5.20.25.6.10.3 9144 purine nucleoside triphosphate metabolism P 0 0 0 0 0 11 30 48 36.7 62.5 6.496 367 0.0.5.20.25.6.10.3.1 9145 purine nucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 368 0.0.5.20.25.6.10.3.1.1 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 369 0.0.5.20.25.6.10.3.1.1.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 370 0.0.5.20.25.6.10.3.1.1.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 371 0.0.5.20.25.6.10.3.3 9205 purine ribonucleoside triphosphate metabolism P 0 0 0 0 0 11 30 48 36.7 62.5 6.496 372 0.0.5.20.25.6.10.3.3.0 46034 ATP metabolism P 1 3 4 33.3 75 8 21 34 38.1 61.8 5.692 373 0.0.5.20.25.6.10.3.3.0.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 374 0.0.5.20.25.6.10.3.3.1 46039 GTP metabolism P 0 0 0 0 0 3 9 14 33.3 64.3 3.156 375 0.0.5.20.25.6.10.3.3.1.0 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 376 0.0.5.20.25.6.10.3.3.3 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 377 0.0.5.20.25.6.10.3.3.3.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 378 0.0.5.20.25.6.10.3.3.3.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 379 0.0.5.20.25.6.10.4 6164 purine nucleotide biosynthesis P 0 3 10 0 30 9 34 61 26.5 55.7 4.554 380 0.0.5.20.25.6.10.4.3 9145 purine nucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 381 0.0.5.20.25.6.10.4.3.1 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 382 0.0.5.20.25.6.10.4.3.1.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 383 0.0.5.20.25.6.10.4.3.1.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 384 0.0.5.20.25.6.10.4.4 9152 purine ribonucleotide biosynthesis P 0 1 1 0 100 9 31 57 29 54.4 4.915 385 0.0.5.20.25.6.10.4.4.2 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 386 0.0.5.20.25.6.10.4.4.2.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 387 0.0.5.20.25.6.10.4.4.2.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 388 0.0.5.20.25.6.10.6 9150 purine ribonucleotide metabolism P 0 0 0 0 0 11 35 62 31.4 56.5 5.787 389 0.0.5.20.25.6.10.6.2 9205 purine ribonucleoside triphosphate metabolism P 0 0 0 0 0 11 30 48 36.7 62.5 6.496 390 0.0.5.20.25.6.10.6.2.0 46034 ATP metabolism P 1 3 4 33.3 75 8 21 34 38.1 61.8 5.692 391 0.0.5.20.25.6.10.6.2.0.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 392 0.0.5.20.25.6.10.6.2.1 46039 GTP metabolism P 0 0 0 0 0 3 9 14 33.3 64.3 3.156 393 0.0.5.20.25.6.10.6.2.1.0 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 394 0.0.5.20.25.6.10.6.2.3 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 395 0.0.5.20.25.6.10.6.2.3.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 396 0.0.5.20.25.6.10.6.2.3.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 397 0.0.5.20.25.6.10.6.3 9152 purine ribonucleotide biosynthesis P 0 1 1 0 100 9 31 57 29 54.4 4.915 398 0.0.5.20.25.6.10.6.3.2 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 399 0.0.5.20.25.6.10.6.3.2.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 400 0.0.5.20.25.6.10.6.3.2.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 401 0.0.5.20.25.6.12.4 6221 pyrimidine nucleotide biosynthesis P 1 2 6 50 33.3 3 12 23 25 52.2 2.499 402 0.0.5.20.25.6.12.4.4 9220 pyrimidine ribonucleotide biosynthesis P 0 1 1 0 100 3 10 14 30 71.4 2.909 403 0.0.5.20.25.6.12.6 9218 pyrimidine ribonucleotide metabolism P 0 0 0 0 0 3 11 15 27.3 73.3 2.692 404 0.0.5.20.25.6.12.6.3 9220 pyrimidine ribonucleotide biosynthesis P 0 1 1 0 100 3 10 14 30 71.4 2.909 405 0.0.5.20.25.6.14 9259 ribonucleotide metabolism P 0 0 0 0 0 12 40 69 30 58 5.83 406 0.0.5.20.25.6.14.0 9150 purine ribonucleotide metabolism P 0 0 0 0 0 11 35 62 31.4 56.5 5.787 407 0.0.5.20.25.6.14.0.2 9205 purine ribonucleoside triphosphate metabolism P 0 0 0 0 0 11 30 48 36.7 62.5 6.496 408 0.0.5.20.25.6.14.0.2.0 46034 ATP metabolism P 1 3 4 33.3 75 8 21 34 38.1 61.8 5.692 409 0.0.5.20.25.6.14.0.2.0.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 410 0.0.5.20.25.6.14.0.2.1 46039 GTP metabolism P 0 0 0 0 0 3 9 14 33.3 64.3 3.156 411 0.0.5.20.25.6.14.0.2.1.0 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 412 0.0.5.20.25.6.14.0.2.3 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 413 0.0.5.20.25.6.14.0.2.3.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 414 0.0.5.20.25.6.14.0.2.3.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 415 0.0.5.20.25.6.14.0.3 9152 purine ribonucleotide biosynthesis P 0 1 1 0 100 9 31 57 29 54.4 4.915 416 0.0.5.20.25.6.14.0.3.2 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 417 0.0.5.20.25.6.14.0.3.2.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 418 0.0.5.20.25.6.14.0.3.2.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 419 0.0.5.20.25.6.14.1 9218 pyrimidine ribonucleotide metabolism P 0 0 0 0 0 3 11 15 27.3 73.3 2.692 420 0.0.5.20.25.6.14.1.3 9220 pyrimidine ribonucleotide biosynthesis P 0 1 1 0 100 3 10 14 30 71.4 2.909 421 0.0.5.20.25.6.14.4 9199 ribonucleoside triphosphate metabolism P 0 0 0 0 0 11 30 48 36.7 62.5 6.496 422 0.0.5.20.25.6.14.4.0 9205 purine ribonucleoside triphosphate metabolism P 0 0 0 0 0 11 30 48 36.7 62.5 6.496 423 0.0.5.20.25.6.14.4.0.0 46034 ATP metabolism P 1 3 4 33.3 75 8 21 34 38.1 61.8 5.692 424 0.0.5.20.25.6.14.4.0.0.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 425 0.0.5.20.25.6.14.4.0.1 46039 GTP metabolism P 0 0 0 0 0 3 9 14 33.3 64.3 3.156 426 0.0.5.20.25.6.14.4.0.1.0 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 427 0.0.5.20.25.6.14.4.0.3 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 428 0.0.5.20.25.6.14.4.0.3.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 429 0.0.5.20.25.6.14.4.0.3.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 430 0.0.5.20.25.6.14.4.2 9201 ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 431 0.0.5.20.25.6.14.4.2.0 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 432 0.0.5.20.25.6.14.4.2.0.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 433 0.0.5.20.25.6.14.4.2.0.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 434 0.0.5.20.25.6.14.5 9260 ribonucleotide biosynthesis P 0 0 0 0 0 10 35 63 28.6 55.6 5.115 435 0.0.5.20.25.6.14.5.0 9152 purine ribonucleotide biosynthesis P 0 1 1 0 100 9 31 57 29 54.4 4.915 436 0.0.5.20.25.6.14.5.0.2 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 437 0.0.5.20.25.6.14.5.0.2.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 438 0.0.5.20.25.6.14.5.0.2.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 439 0.0.5.20.25.6.14.5.1 9220 pyrimidine ribonucleotide biosynthesis P 0 1 1 0 100 3 10 14 30 71.4 2.909 440 0.0.5.20.25.6.14.5.4 9201 ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 441 0.0.5.20.25.6.14.5.4.0 9206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 9 26 43 34.6 60.5 5.63 442 0.0.5.20.25.6.14.5.4.0.1 6754 ATP biosynthesis P 4 14 22 28.6 63.6 6 17 29 35.3 58.6 4.661 443 0.0.5.20.25.6.14.5.4.0.2 6183 GTP biosynthesis P 3 9 14 33.3 64.3 3 9 14 33.3 64.3 3.156 444 0.0.5.20.25.10 16070 RNA metabolism P 0 2 3 0 66.7 20 175 297 11.4 58.9 2.447 445 0.0.5.20.25.10.3 6396 RNA processing P 4 37 67 10.8 55.2 20 159 273 12.6 58.2 2.911 446 0.0.5.20.25.10.3.0 6397 mRNA processing P 3 29 44 10.3 65.9 12 96 137 12.5 70.1 2.221 447 0.0.5.20.25.10.3.0.5 398 "nuclear mRNA splicing\, via spliceosome" P 7 49 71 14.3 69 9 60 86 15 69.8 2.523 448 0.0.5.20.25.10.3.3 8380 RNA splicing P 2 7 13 28.6 53.8 9 65 97 13.8 67 2.256 449 0.0.5.20.25.10.3.3.1 375 "RNA splicing\, via transesterification reactions" P 0 0 0 0 0 9 60 86 15 69.8 2.523 450 0.0.5.20.25.10.3.3.1.0 377 "RNA splicing\, via transesterification reactions with bulged adenosine as nucleophile" P 0 0 0 0 0 9 60 86 15 69.8 2.523 451 0.0.5.20.25.10.3.3.1.0.2 398 "nuclear mRNA splicing\, via spliceosome" P 7 49 71 14.3 69 9 60 86 15 69.8 2.523 452 0.0.5.20.25.11 6350 transcription P 7 47 98 14.9 48 39 903 2072 4.3 43.6 -3.198 453 0.0.5.20.25.11.0 45449 regulation of transcription P 0 2 4 0 50 30 829 1938 3.6 42.8 -3.897 454 0.0.5.20.25.11.0.2 6355 "regulation of transcription\, DNA-dependent" P 22 685 1727 3.2 39.7 29 823 1924 3.5 42.8 -3.996 455 0.0.5.20.25.11.1 6351 "transcription\, DNA-dependent" P 0 4 6 0 66.7 35 881 2018 4 43.7 -3.589 456 0.0.5.20.25.11.1.2 6355 "regulation of transcription\, DNA-dependent" P 22 685 1727 3.2 39.7 29 823 1924 3.5 42.8 -3.996 457 0.0.5.20.27.1.20.7 6633 fatty acid biosynthesis P 4 15 27 26.7 55.6 5 28 44 17.9 63.6 2.32 458 0.0.5.20.27.1.30.2 6633 fatty acid biosynthesis P 4 15 27 26.7 55.6 5 28 44 17.9 63.6 2.32 459 0.0.5.20.27.5.0.7 6633 fatty acid biosynthesis P 4 15 27 26.7 55.6 5 28 44 17.9 63.6 2.32 460 0.0.5.20.29 6119 oxidative phosphorylation P 1 1 4 100 25 7 18 52 38.9 34.6 5.402 461 0.0.5.20.29.0 42773 ATP synthesis coupled electron transport P 0 0 0 0 0 4 14 43 28.6 32.6 3.23 462 0.0.5.20.29.0.1 42775 ATP synthesis coupled electron transport (sensu Eukarya) P 0 0 0 0 0 4 14 43 28.6 32.6 3.23 463 0.0.5.20.29.0.1.1 6120 "mitochondrial electron transport\, NADH to ubiquinone" P 4 14 36 28.6 38.9 4 14 36 28.6 38.9 3.23 464 0.0.5.20.33.0.1.0 42773 ATP synthesis coupled electron transport P 0 0 0 0 0 4 14 43 28.6 32.6 3.23 465 0.0.5.20.33.0.1.0.1 42775 ATP synthesis coupled electron transport (sensu Eukarya) P 0 0 0 0 0 4 14 43 28.6 32.6 3.23 466 0.0.5.20.33.0.1.0.1.1 6120 "mitochondrial electron transport\, NADH to ubiquinone" P 4 14 36 28.6 38.9 4 14 36 28.6 38.9 3.23 467 0.0.5.20.35 19538 protein metabolism P 0 10 15 0 66.7 115 1343 2803 8.6 47.9 2.813 468 0.0.5.20.35.4 42157 lipoprotein metabolism P 0 0 1 0 0 3 12 22 25 54.5 2.499 469 0.0.5.20.35.4.0 42158 lipoprotein biosynthesis P 0 0 0 0 0 3 10 19 30 52.6 2.909 470 0.0.5.20.35.4.0.0 6497 protein lipidation P 0 0 0 0 0 3 10 19 30 52.6 2.909 471 0.0.5.20.35.9 6412 protein biosynthesis P 20 132 243 15.2 54.3 43 316 597 13.6 52.9 4.895 472 0.0.5.20.35.9.1 6418 amino acid activation P 2 5 24 40 20.8 6 25 75 24 33.3 3.412 473 0.0.5.20.35.9.11 42158 lipoprotein biosynthesis P 0 0 0 0 0 3 10 19 30 52.6 2.909 474 0.0.5.20.35.9.11.0 6497 protein lipidation P 0 0 0 0 0 3 10 19 30 52.6 2.909 475 0.0.5.20.35.9.18 6417 regulation of protein biosynthesis P 3 12 18 25 66.7 3 13 21 23.1 61.9 2.326 476 0.0.5.20.35.9.19 6445 regulation of translation P 0 12 21 0 57.1 7 41 66 17.1 62.1 2.61 477 0.0.5.20.35.9.19.7 6446 regulation of translational initiation P 7 22 33 31.8 66.7 7 23 34 30.4 67.6 4.498 478 0.0.5.20.35.9.29 6413 translational initiation P 2 17 31 11.8 54.8 9 40 64 22.5 62.5 3.943 479 0.0.5.20.35.9.29.3 6446 regulation of translational initiation P 7 22 33 31.8 66.7 7 23 34 30.4 67.6 4.498 480 0.0.5.20.35.10.3.9 19941 modification-dependent protein catabolism P 0 0 0 0 0 12 69 143 17.4 48.3 3.499 481 0.0.5.20.35.10.3.9.3 6511 ubiquitin-dependent protein catabolism P 11 67 140 16.4 47.9 12 69 143 17.4 48.3 3.499 482 0.0.5.20.35.11 6461 protein complex assembly P 7 61 85 11.5 71.8 9 68 92 13.2 73.9 2.107 483 0.0.5.20.35.12 6457 protein folding P 10 74 151 13.5 49 10 74 151 13.5 49 2.295 484 0.0.5.20.35.14.47 6497 protein lipidation P 0 0 0 0 0 3 10 19 30 52.6 2.909 485 0.0.5.20.35.16 6605 protein targeting P 7 34 44 20.6 77.3 14 86 112 16.3 76.8 3.499 486 0.0.5.20.35.16.1 45047 protein-ER targeting P 0 0 0 0 0 4 8 9 50 88.9 4.846 487 0.0.5.20.35.16.1.0 6613 cotranslational membrane targeting P 3 6 7 50 85.7 3 6 7 50 85.7 4.196 488 0.0.5.20.35.16.4 6612 protein-membrane targeting P 1 2 2 50 100 4 8 9 50 88.9 4.846 489 0.0.5.20.35.16.4.0 6613 cotranslational membrane targeting P 3 6 7 50 85.7 3 6 7 50 85.7 4.196 490 0.0.5.20.35.16.5 6626 protein-mitochondrial targeting P 0 1 1 0 100 3 14 19 21.4 73.7 2.169 491 0.0.5.20.37.3.18 6417 regulation of protein biosynthesis P 3 12 18 25 66.7 3 13 21 23.1 61.9 2.326 492 0.0.5.20.38 19748 secondary metabolism P 0 0 0 0 0 3 7 9 42.9 77.8 3.783 493 0.0.5.20.38.6 6595 polyamine metabolism P 0 1 2 0 50 3 7 9 42.9 77.8 3.783 494 0.0.5.20.38.6.0 6596 polyamine biosynthesis P 3 3 4 100 75 3 6 7 50 85.7 4.196 495 0.0.5.33 9719 response to endogenous stimulus P 0 0 0 0 0 18 132 236 13.6 55.9 3.134 496 0.0.5.33.2 6974 response to DNA damage stimulus P 0 5 11 0 45.5 18 132 237 13.6 55.7 3.134 497 0.0.5.33.2.3 6281 DNA repair P 8 73 116 11 62.9 16 114 204 14 55.9 3.079 498 0.0.5.33.2.3.11 6289 nucleotide-excision repair P 3 10 20 30 50 3 14 25 21.4 56 2.169 499 0.0.5.34 9605 response to external stimulus P 0 5 6 0 83.3 29 749 1783 3.9 42 -3.39 500 0.0.5.34.1 9581 perception of external stimulus P 0 0 0 0 0 4 180 624 2.2 28.8 -2.48 501 0.0.5.34.1.0 9582 perception of abiotic stimulus P 0 2 4 0 50 4 163 589 2.5 27.7 -2.238 502 0.0.5.34.1.3 7600 sensory perception P 0 10 21 0 47.6 4 169 597 2.4 28.3 -2.326 503 0.0.5.34.2 9628 response to abiotic stimulus P 0 1 1 0 100 10 284 810 3.5 35.1 -2.253 504 0.0.5.34.2.0 9582 perception of abiotic stimulus P 0 2 4 0 50 4 163 589 2.5 27.7 -2.238 505 0.0.5.34.3 9607 response to biotic stimulus P 0 2 2 0 100 19 512 1044 3.7 49 -2.901 506 0.0.5.34.3.1 6952 defense response P 2 34 73 5.9 46.6 13 466 953 2.8 48.9 -3.574 507 0.0.5.34.3.1.3 6955 immune response P 4 229 574 1.7 39.9 12 436 889 2.8 49 -3.481 508 0.0.5.34.3.8 9613 response to pest/pathogen/parasite P 0 4 13 0 30.8 9 280 432 3.2 64.8 -2.444 509 0.0.5.35.3 6974 response to DNA damage stimulus P 0 5 11 0 45.5 18 132 237 13.6 55.7 3.134 510 0.0.5.35.3.3 6281 DNA repair P 8 73 116 11 62.9 16 114 204 14 55.9 3.079 511 0.0.5.35.3.3.11 6289 nucleotide-excision repair P 3 10 20 30 50 3 14 25 21.4 56 2.169 512 0.0.5.35.13 9613 response to pest/pathogen/parasite P 0 4 13 0 30.8 9 280 432 3.2 64.8 -2.444 513 0.0.5.36.7 9306 protein secretion P 4 17 30 23.5 56.7 4 17 30 23.5 56.7 2.735 514 0.1.0.7 5622 intracellular C 17 235 665 7.2 35.3 289 3212 6357 9 50.5 6.647 515 0.1.0.7.4 5694 chromosome C 1 8 48 12.5 16.7 9 57 163 15.8 35 2.696 516 0.1.0.7.4.7 228 nuclear chromosome C 2 6 11 33.3 54.5 3 10 19 30 52.6 2.909 517 0.1.0.7.7 5737 cytoplasm C 34 377 601 9 62.7 198 1758 2986 11.3 58.9 8.533 518 0.1.0.7.7.9.2.0.1 30125 clathrin vesicle coat C 3 14 25 21.4 56 3 15 31 20 48.4 2.026 519 0.1.0.7.7.9.2.4.0 30125 clathrin vesicle coat C 3 14 25 21.4 56 3 15 31 20 48.4 2.026 520 0.1.0.7.7.10 5856 cytoskeleton C 13 150 247 8.7 60.7 35 342 697 10.2 49.1 2.565 521 0.1.0.7.7.10.3 15630 microtubule cytoskeleton C 1 6 6 16.7 100 12 89 206 13.5 43.2 2.508 522 0.1.0.7.7.10.3.3 5819 spindle C 2 8 11 25 72.7 5 28 40 17.9 70 2.32 523 0.1.0.7.7.11 5829 cytosol C 15 115 156 13 73.7 23 193 283 11.9 68.2 2.846 524 0.1.0.7.7.11.14 502 proteasome complex (sensu Eukarya) C 0 1 1 0 100 5 22 30 22.7 73.3 2.963 525 0.1.0.7.7.16 5783 endoplasmic reticulum C 23 166 260 13.9 63.8 41 232 362 17.7 64.1 6.665 526 0.1.0.7.7.16.2 5789 endoplasmic reticulum membrane C 5 21 33 23.8 63.6 9 30 45 30 66.7 5.045 527 0.1.0.7.7.16.5 502 proteasome complex (sensu Eukarya) C 0 1 1 0 100 5 22 30 22.7 73.3 2.963 528 0.1.0.7.7.16.6 5791 rough endoplasmic reticulum C 1 2 2 50 100 3 4 5 75 80 5.409 529 0.1.0.7.7.16.10 5786 signal recognition particle C 3 7 10 42.9 70 3 7 10 42.9 70 3.783 530 0.1.0.7.7.35.0 30118 clathrin coat C 0 0 0 0 0 3 15 31 20 48.4 2.026 531 0.1.0.7.7.35.0.2 30125 clathrin vesicle coat C 3 14 25 21.4 56 3 15 31 20 48.4 2.026 532 0.1.0.7.7.35.2.0 30125 clathrin vesicle coat C 3 14 25 21.4 56 3 15 31 20 48.4 2.026 533 0.1.0.7.7.38 5739 mitochondrion C 49 296 445 16.6 66.5 54 335 541 16.1 61.9 6.915 534 0.1.0.7.7.38.4 5759 mitochondrial matrix C 2 19 29 10.5 65.5 7 42 64 16.7 65.6 2.538 535 0.1.0.7.7.38.4.7 5761 mitochondrial ribosome C 1 6 7 16.7 85.7 5 16 26 31.2 61.5 3.879 536 0.1.0.7.7.38.4.7.1 5763 mitochondrial small ribosomal subunit C 3 8 13 37.5 61.5 3 8 13 37.5 61.5 3.443 537 0.1.0.7.7.38.5 5740 mitochondrial membrane C 1 7 13 14.3 53.8 16 73 159 21.9 45.9 5.142 538 0.1.0.7.7.38.5.0 5743 mitochondrial inner membrane C 2 24 59 8.3 40.7 13 52 113 25 46 5.218 539 0.1.0.7.7.38.5.0.2 5746 mitochondrial electron transport chain C 4 5 14 80 35.7 5 7 26 71.4 26.9 6.782 540 0.1.0.7.7.38.5.0.7 5753 proton-transporting ATP synthase complex (sensu Eukarya) C 4 11 12 36.4 91.7 4 11 14 36.4 78.6 3.889 541 0.1.0.7.7.54 5840 ribosome C 14 89 172 15.7 51.7 15 112 214 13.4 52.3 2.78 542 0.1.0.7.7.54.3 313 organellar ribosome C 0 0 0 0 0 5 16 26 31.2 61.5 3.879 543 0.1.0.7.7.54.3.0 5761 mitochondrial ribosome C 1 6 7 16.7 85.7 5 16 26 31.2 61.5 3.879 544 0.1.0.7.7.54.3.0.1 5763 mitochondrial small ribosomal subunit C 3 8 13 37.5 61.5 3 8 13 37.5 61.5 3.443 545 0.1.0.7.7.54.3.2 314 organellar small ribosomal subunit C 0 0 0 0 0 3 8 13 37.5 61.5 3.443 546 0.1.0.7.7.54.3.2.0 5763 mitochondrial small ribosomal subunit C 3 8 13 37.5 61.5 3 8 13 37.5 61.5 3.443 547 0.1.0.7.7.54.5 15935 small ribosomal subunit C 1 4 8 25 50 6 34 51 17.6 66.7 2.509 548 0.1.0.7.7.54.5.3 314 organellar small ribosomal subunit C 0 0 0 0 0 3 8 13 37.5 61.5 3.443 549 0.1.0.7.7.54.5.3.0 5763 mitochondrial small ribosomal subunit C 3 8 13 37.5 61.5 3 8 13 37.5 61.5 3.443 550 0.1.0.7.21 5634 nucleus C 101 1391 2847 7.3 48.9 125 1541 3107 8.1 49.6 2.272 551 0.1.0.7.21.9 228 nuclear chromosome C 2 6 11 33.3 54.5 3 10 19 30 52.6 2.909 552 0.1.0.7.21.15 5635 nuclear membrane C 2 14 22 14.3 63.6 8 48 72 16.7 66.7 2.714 553 0.1.0.7.21.15.4 5643 nuclear pore C 5 28 43 17.9 65.1 5 28 43 17.9 65.1 2.32 554 0.1.0.7.21.17 5730 nucleolus C 3 28 40 10.7 70 8 49 77 16.3 63.6 2.647 555 0.1.0.7.21.17.9 5732 small nucleolar ribonucleoprotein complex C 4 15 27 26.7 55.6 4 15 27 26.7 55.6 3.051 556 0.1.0.7.21.18 5654 nucleoplasm C 4 27 39 14.8 69.2 16 128 204 12.5 62.7 2.571 557 0.1.0.7.21.22 502 proteasome complex (sensu Eukarya) C 0 1 1 0 100 5 22 30 22.7 73.3 2.963 558 0.1.0.7.21.28 5681 spliceosome complex C 4 22 40 18.2 55 5 27 46 18.5 58.7 2.415 559 0.1.0.7.23 45259 proton-transporting ATP synthase complex C 0 0 0 0 0 4 11 14 36.4 78.6 3.889 560 0.1.0.7.23.2 5753 proton-transporting ATP synthase complex (sensu Eukarya) C 4 11 12 36.4 91.7 4 11 14 36.4 78.6 3.889 561 0.1.0.7.32 30529 ribonucleoprotein complex C 7 29 46 24.1 63 32 181 334 17.7 54.2 5.869 562 0.1.0.7.32.5 5840 ribosome C 14 89 172 15.7 51.7 15 112 214 13.4 52.3 2.78 563 0.1.0.7.32.5.3 313 organellar ribosome C 0 0 0 0 0 5 16 26 31.2 61.5 3.879 564 0.1.0.7.32.5.3.0 5761 mitochondrial ribosome C 1 6 7 16.7 85.7 5 16 26 31.2 61.5 3.879 565 0.1.0.7.32.5.3.0.1 5763 mitochondrial small ribosomal subunit C 3 8 13 37.5 61.5 3 8 13 37.5 61.5 3.443 566 0.1.0.7.32.5.3.2 314 organellar small ribosomal subunit C 0 0 0 0 0 3 8 13 37.5 61.5 3.443 567 0.1.0.7.32.5.3.2.0 5763 mitochondrial small ribosomal subunit C 3 8 13 37.5 61.5 3 8 13 37.5 61.5 3.443 568 0.1.0.7.32.5.5 15935 small ribosomal subunit C 1 4 8 25 50 6 34 51 17.6 66.7 2.509 569 0.1.0.7.32.5.5.3 314 organellar small ribosomal subunit C 0 0 0 0 0 3 8 13 37.5 61.5 3.443 570 0.1.0.7.32.5.5.3.0 5763 mitochondrial small ribosomal subunit C 3 8 13 37.5 61.5 3 8 13 37.5 61.5 3.443 571 0.1.0.7.32.8 5732 small nucleolar ribonucleoprotein complex C 4 15 27 26.7 55.6 4 15 27 26.7 55.6 3.051 572 0.1.0.7.32.9 5681 spliceosome complex C 4 22 40 18.2 55 5 27 46 18.5 58.7 2.415 573 0.1.0.8.1 12505 endomembrane system C 0 1 1 0 100 17 95 151 17.9 62.9 4.309 574 0.1.0.8.1.1 42175 nuclear envelope-endoplasmic reticulum network C 0 0 0 0 0 10 33 48 30.3 68.8 5.362 575 0.1.0.8.1.1.1 5789 endoplasmic reticulum membrane C 5 21 33 23.8 63.6 9 30 45 30 66.7 5.045 576 0.1.0.8.1.3 5635 nuclear membrane C 2 14 22 14.3 63.6 8 48 72 16.7 66.7 2.714 577 0.1.0.8.1.3.4 5643 nuclear pore C 5 28 43 17.9 65.1 5 28 43 17.9 65.1 2.32 578 0.1.0.8.6 19866 inner membrane C 4 17 29 23.5 58.6 13 61 126 21.3 48.4 4.507 579 0.1.0.8.6.0 5743 mitochondrial inner membrane C 2 24 59 8.3 40.7 13 52 113 25 46 5.218 580 0.1.0.8.6.0.2 5746 mitochondrial electron transport chain C 4 5 14 80 35.7 5 7 26 71.4 26.9 6.782 581 0.1.0.8.6.0.7 5753 proton-transporting ATP synthase complex (sensu Eukarya) C 4 11 12 36.4 91.7 4 11 14 36.4 78.6 3.889 582 0.1.0.8.7.4 5887 integral to plasma membrane C 18 648 965 2.8 67.2 22 749 1159 2.9 64.6 -4.463 583 0.1.0.8.7.9 46930 pore complex C 0 0 0 0 0 5 28 42 17.9 66.7 2.32 584 0.1.0.8.7.9.1 5643 nuclear pore C 5 28 43 17.9 65.1 5 28 43 17.9 65.1 2.32 585 0.1.0.8.7.10 16469 proton-transporting two-sector ATPase complex C 3 8 9 37.5 88.9 6 16 20 37.5 80 4.872 586 0.1.0.8.7.10.0 45255 hydrogen-translocating F-type ATPase complex C 0 0 0 0 0 4 11 14 36.4 78.6 3.889 587 0.1.0.8.7.10.0.3 5753 proton-transporting ATP synthase complex (sensu Eukarya) C 4 11 12 36.4 91.7 4 11 14 36.4 78.6 3.889 588 0.1.0.8.9 5740 mitochondrial membrane C 1 7 13 14.3 53.8 16 73 159 21.9 45.9 5.142 589 0.1.0.8.9.0 5743 mitochondrial inner membrane C 2 24 59 8.3 40.7 13 52 113 25 46 5.218 590 0.1.0.8.9.0.2 5746 mitochondrial electron transport chain C 4 5 14 80 35.7 5 7 26 71.4 26.9 6.782 591 0.1.0.8.9.0.7 5753 proton-transporting ATP synthase complex (sensu Eukarya) C 4 11 12 36.4 91.7 4 11 14 36.4 78.6 3.889 592 0.1.0.8.10 19867 outer membrane C 3 9 14 33.3 64.3 5 22 47 22.7 46.8 2.963 593 0.1.0.8.13 5886 plasma membrane C 14 178 260 7.9 68.5 41 1006 1577 4.1 63.8 -3.735 594 0.1.0.8.13.19 5887 integral to plasma membrane C 18 648 965 2.8 67.2 22 749 1159 2.9 64.6 -4.463 595 0.1.2 5576 extracellular C 4 182 552 2.2 33 6 519 1108 1.2 46.8 -5.321 596 0.1.4 8370 obsolete cellular component C 0 0 0 0 0 19 130 167 14.6 77.8 3.557 597 0.1.4.0 5837 26S proteasome C 6 30 35 20 85.7 6 30 35 20 85.7 2.868 598 0.1.4.42 8304 eukaryotic translation initiation factor 4 complex C 4 7 9 57.1 77.8 4 7 9 57.1 77.8 5.282 599 0.1.4.94 5803 secretory vesicle C 5 25 34 20 73.5 5 25 34 20 73.5 2.618 600 0.2 3674 molecular_function F 0 0 0 0 0 422 6402 16003 6.6 40 -2.529 601 0.2.2 16209 antioxidant activity F 1 3 3 33.3 100 7 27 54 25.9 50 3.944 602 0.2.2.5 4601 peroxidase activity F 6 21 47 28.6 44.7 6 21 47 28.6 44.7 3.958 603 0.2.4.8 8144 drug binding F 1 2 3 50 66.7 3 10 15 30 66.7 2.909 604 0.2.4.19.3.7 8270 zinc ion binding F 6 205 499 2.9 41.1 6 205 499 2.9 41.1 -2.245 605 0.2.4.22.0.3 3682 chromatin binding F 4 21 48 19 43.8 5 23 52 21.7 44.2 2.842 606 0.2.4.22.0.4 3684 damaged DNA binding F 6 24 49 25 49 6 24 49 25 49 3.538 607 0.2.4.22.0.21 3697 single-stranded DNA binding F 4 23 30 17.4 76.7 4 23 30 17.4 76.7 2.013 608 0.2.4.22.0.23 3700 transcription factor activity F 12 444 992 2.7 44.8 13 455 1008 2.9 45.1 -3.47 609 0.2.4.22.1 3723 RNA binding F 32 254 450 12.6 56.4 39 315 560 12.4 56.2 4.003 610 0.2.4.22.1.5 3729 mRNA binding F 3 9 11 33.3 81.8 11 70 95 15.7 73.7 2.965 611 0.2.4.22.1.5.5 8248 pre-mRNA splicing factor activity F 8 50 71 16 70.4 8 50 71 16 70.4 2.583 612 0.2.4.22.2 8135 "translation factor activity\, nucleic acid binding" F 1 4 5 25 80 13 68 112 19.1 60.7 4.04 613 0.2.4.22.2.7 3743 translation initiation factor activity F 10 43 71 23.3 60.6 10 43 71 23.3 60.6 4.287 614 0.2.4.23 166 nucleotide binding F 5 79 176 6.3 44.9 74 820 1910 9 42.9 2.661 615 0.2.4.23.2 17076 purine nucleotide binding F 0 1 1 0 100 74 813 1892 9.1 43 2.741 616 0.2.4.23.2.1 19001 guanyl nucleotide binding F 0 0 0 0 0 23 160 353 14.4 45.3 3.832 617 0.2.4.23.2.1.2 5525 GTP binding F 23 156 348 14.7 44.8 23 156 348 14.7 44.8 3.968 618 0.2.4.27.5 5048 signal sequence binding F 1 3 4 33.3 75 3 14 19 21.4 73.7 2.169 619 0.2.4.32 5102 receptor binding F 1 43 69 2.3 62.3 6 282 552 2.1 51.1 -3.192 620 0.2.5 3824 catalytic activity F 5 69 225 7.2 30.7 201 2470 5598 8.1 44.1 3.222 621 0.2.5.20.1 16817 "hydrolase activity\, acting on acid anhydrides" F 0 0 0 0 0 36 315 688 11.4 45.8 3.317 622 0.2.5.20.1.0 16820 "hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances" F 0 0 0 0 0 10 73 147 13.7 49.7 2.342 623 0.2.5.20.1.0.0 42626 "ATPase activity\, coupled to transmembrane movement of substances" F 0 0 0 0 0 10 73 147 13.7 49.7 2.342 624 0.2.5.20.1.0.0.2.0.7 8553 "hydrogen-exporting ATPase activity\, phosphorylative mechanism" F 3 8 12 37.5 66.7 3 8 12 37.5 66.7 3.443 625 0.2.5.20.1.1 16818 "hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides" F 0 0 0 0 0 35 298 653 11.7 45.6 3.444 626 0.2.5.20.1.1.6 16887 ATPase activity F 0 9 25 0 36 17 148 334 11.5 44.3 2.274 627 0.2.5.20.1.1.6.0 42623 "ATPase activity\, coupled" F 0 0 0 0 0 17 145 327 11.7 44.3 2.365 628 0.2.5.20.1.1.6.0.1 42626 "ATPase activity\, coupled to transmembrane movement of substances" F 0 0 0 0 0 10 73 147 13.7 49.7 2.342 629 0.2.5.20.1.1.6.0.1.2.0.7 8553 "hydrogen-exporting ATPase activity\, phosphorylative mechanism" F 3 8 12 37.5 66.7 3 8 12 37.5 66.7 3.443 630 0.2.5.20.1.1.6.0.2 8094 DNA dependent ATPase activity F 2 8 20 25 40 4 16 44 25 36.4 2.887 631 0.2.5.20.1.1.20 3924 GTPase activity F 1 16 36 6.2 44.4 17 135 287 12.6 47 2.685 632 0.2.5.20.1.1.20.4 3925 small monomeric GTPase activity F 3 26 71 11.5 36.6 12 89 196 13.5 45.4 2.508 633 0.2.5.20.1.1.20.4.3 3930 RAS small monomeric GTPase activity F 3 13 40 23.1 32.5 3 13 40 23.1 32.5 2.326 634 0.2.5.22.0.13.0 42027 cyclophilin-type peptidyl-prolyl cis-trans isomerase activity F 3 15 29 20 51.7 3 15 29 20 51.7 2.026 635 0.2.5.23.43.0.3 4683 calmodulin regulated protein kinase activity F 0 0 1 0 0 3 11 19 27.3 57.9 2.692 636 0.2.5.23.43.0.3.6 4689 phosphorylase kinase activity F 0 1 2 0 50 3 6 7 50 85.7 4.196 637 0.2.5.23.43.0.3.6.1 8607 "phosphorylase kinase\, intrinsic regulator activity" F 3 3 3 100 100 3 3 3 100 100 6.402 638 0.2.5.24 16874 ligase activity F 14 82 156 17.1 52.6 17 124 298 13.7 41.6 3.069 639 0.2.5.24.3 16879 "ligase activity\, forming carbon-nitrogen bonds" F 0 0 0 0 0 10 69 173 14.5 39.9 2.539 640 0.2.5.24.3.1 16881 acid-D-amino acid ligase activity F 0 0 0 0 0 8 53 139 15.1 38.1 2.397 641 0.2.5.24.3.1.22 4842 ubiquitin-protein ligase activity F 8 46 116 17.4 39.7 8 46 116 17.4 39.7 2.852 642 0.2.5.24.4 16875 "ligase activity\, forming carbon-oxygen bonds" F 0 0 0 0 0 6 26 75 23.1 34.7 3.293 643 0.2.5.24.4.0 16876 "ligase activity\, forming aminoacyl-tRNA and related compounds" F 0 0 0 0 0 6 26 75 23.1 34.7 3.293 644 0.2.5.24.4.0.4 4812 tRNA ligase activity F 2 6 23 33.3 26.1 6 26 75 23.1 34.7 3.293 645 0.2.5.24.6 16886 "ligase activity\, forming phosphoric ester bonds" F 0 0 0 0 0 6 33 86 18.2 38.4 2.594 646 0.2.5.24.6.1 8452 RNA ligase activity F 0 0 0 0 0 6 26 75 23.1 34.7 3.293 647 0.2.5.24.6.1.2 4812 tRNA ligase activity F 2 6 23 33.3 26.1 6 26 75 23.1 34.7 3.293 648 0.2.5.26.1 16830 carbon-carbon lyase activity F 0 0 0 0 0 4 19 34 21.1 55.9 2.463 649 0.2.5.33 16491 oxidoreductase activity F 34 250 472 13.6 53 42 359 748 11.7 48 3.762 650 0.2.5.33.32 16651 "oxidoreductase activity\, acting on NADH or NADPH" F 0 0 0 0 0 9 42 77 21.4 54.5 3.765 651 0.2.5.33.32.5 16659 "oxidoreductase activity\, acting on NADH or NADPH\, other acceptor" F 0 0 0 0 0 8 28 38 28.6 73.7 4.573 652 0.2.5.33.32.5.3 3954 NADH dehydrogenase activity F 8 26 36 30.8 72.2 8 26 36 30.8 72.2 4.851 653 0.2.5.33.32.6 16655 "oxidoreductase activity\, acting on NADH or NADPH\, quinone or similar compound as acceptor" F 0 0 0 0 0 8 29 57 27.6 50.9 4.443 654 0.2.5.33.32.6.3 8137 NADH dehydrogenase (ubiquinone) activity F 8 26 54 30.8 48.1 8 26 54 30.8 48.1 4.851 655 0.2.5.33.36 16684 "oxidoreductase activity\, acting on peroxide as acceptor" F 0 0 0 0 0 6 22 48 27.3 45.8 3.81 656 0.2.5.33.36.16 4601 peroxidase activity F 6 21 47 28.6 44.7 6 21 47 28.6 44.7 3.958 657 0.2.5.43 8639 small protein conjugating enzyme activity F 0 0 1 0 0 6 40 73 15 54.8 2.057 658 0.2.5.43.1 4840 ubiquitin conjugating enzyme activity F 6 39 71 15.4 54.9 6 39 71 15.4 54.9 2.126 659 0.2.5.47.11 16765 "transferase activity\, transferring alkyl or aryl (other than methyl) groups" F 0 0 0 0 0 6 34 55 17.6 61.8 2.509 660 0.2.5.47.11.18 4364 glutathione transferase activity F 3 14 21 21.4 66.7 3 14 21 21.4 66.7 2.169 661 0.2.5.47.11.31 4659 prenyltransferase activity F 0 2 4 0 50 3 11 22 27.3 50 2.692 662 0.2.5.47.13.1.31 4576 oligosaccharyl transferase activity F 2 2 5 100 40 4 5 8 80 62.5 6.491 663 0.2.5.47.16.5.15 3899 DNA-directed RNA polymerase activity F 3 19 34 15.8 55.9 4 21 36 19 58.3 2.225 664 0.2.5.47.16.6.89.0.3 4683 calmodulin regulated protein kinase activity F 0 0 1 0 0 3 11 19 27.3 57.9 2.692 665 0.2.5.47.16.6.89.0.3.6 4689 phosphorylase kinase activity F 0 1 2 0 50 3 6 7 50 85.7 4.196 666 0.2.5.47.16.6.89.0.3.6.1 8607 "phosphorylase kinase\, intrinsic regulator activity" F 3 3 3 100 100 3 3 3 100 100 6.402 667 0.2.5.47.16.11 16776 "phosphotransferase activity\, phosphate group as acceptor" F 0 1 1 0 100 4 21 31 19 67.7 2.225 668 0.2.6 5194 cell adhesion molecule activity F 2 164 327 1.2 50.2 5 208 407 2.4 51.1 -2.566 669 0.2.11 3754 chaperone activity F 9 58 118 15.5 49.2 12 92 169 13 54.4 2.382 670 0.2.15.8.3 19887 protein kinase regulator activity F 0 0 0 0 0 4 11 22 36.4 50 3.889 671 0.2.15.8.3.7 8607 "phosphorylase kinase\, intrinsic regulator activity" F 3 3 3 100 100 3 3 3 100 100 6.402 672 0.2.20.163 8436 heterogeneous nuclear ribonucleoprotein F 4 12 14 33.3 85.7 4 12 14 33.3 85.7 3.645 673 0.2.23 4871 signal transducer activity F 10 134 277 7.5 48.4 39 1188 3058 3.3 38.8 -5.311 674 0.2.23.5 4872 receptor activity F 19 344 1085 5.5 31.7 24 734 2183 3.3 33.6 -4.035 675 0.2.23.5.16 4888 transmembrane receptor activity F 2 71 119 2.8 59.7 9 500 1597 1.8 31.3 -4.623 676 0.2.23.6 5102 receptor binding F 1 43 69 2.3 62.3 6 282 552 2.1 51.1 -3.192 677 0.2.24.7 5200 structural constituent of cytoskeleton F 8 57 113 14 50.4 8 57 113 14 50.4 2.168 678 0.2.24.21 3735 structural constituent of ribosome F 17 119 240 14.3 49.6 17 119 240 14.3 49.6 3.256 679 0.2.27 30528 transcription regulator activity F 0 5 12 0 41.7 18 631 1242 2.9 50.8 -4.147 680 0.2.27.6 3700 transcription factor activity F 12 444 992 2.7 44.8 13 455 1008 2.9 45.1 -3.47 681 0.2.28 45182 translation regulator activity F 0 1 1 0 100 13 70 114 18.6 61.4 3.918 682 0.2.28.1 8135 "translation factor activity\, nucleic acid binding" F 1 4 5 25 80 13 68 112 19.1 60.7 4.04 683 0.2.28.1.7 3743 translation initiation factor activity F 10 43 71 23.3 60.6 10 43 71 23.3 60.6 4.287 684 0.2.29 5215 transporter activity F 15 174 418 8.6 41.6 90 984 2128 9.1 46.2 3.118 685 0.2.29.5 5386 carrier activity F 1 10 16 10 62.5 30 255 564 11.8 45.2 3.188 686 0.2.29.5.3 15399 primary active transporter activity F 0 0 0 0 0 27 128 264 21.1 48.5 6.462 687 0.2.29.5.3.5 8137 NADH dehydrogenase (ubiquinone) activity F 8 26 54 30.8 48.1 8 26 54 30.8 48.1 4.851 688 0.2.29.5.3.7 15405 P-P-bond-hydrolysis-driven transporter activity F 0 0 0 0 0 14 88 168 15.9 52.4 3.402 689 0.2.29.5.3.7.1.7 8553 "hydrogen-exporting ATPase activity\, phosphorylative mechanism" F 3 8 12 37.5 66.7 3 8 12 37.5 66.7 3.443 690 0.2.29.5.3.7.6 15450 protein translocase activity F 4 15 21 26.7 71.4 4 15 21 26.7 71.4 3.051 691 0.2.29.6 15267 channel/pore class transporter activity F 0 5 9 0 55.6 7 218 468 3.2 46.6 -2.149 692 0.2.29.6.0 15268 alpha-type channel activity F 0 0 0 0 0 7 212 451 3.3 47 -2.065 693 0.2.29.6.0.1.2 5261 cation channel activity F 1 17 64 5.9 26.6 3 138 306 2.2 45.1 -2.188 694 0.2.29.8 5489 electron transporter activity F 16 138 331 11.6 41.7 24 175 382 13.7 45.8 3.661 695 0.2.29.8.17 3954 NADH dehydrogenase activity F 8 26 36 30.8 72.2 8 26 36 30.8 72.2 4.851 696 0.2.29.11 15075 ion transporter activity F 2 11 17 18.2 64.7 27 177 379 15.3 46.7 4.506 697 0.2.29.11.1 8324 cation transporter activity F 1 8 26 12.5 30.8 24 138 276 17.4 50 4.973 698 0.2.29.11.1.0.7 8553 "hydrogen-exporting ATPase activity\, phosphorylative mechanism" F 3 8 12 37.5 66.7 3 8 12 37.5 66.7 3.443 699 0.2.29.11.1.4 15077 monovalent inorganic cation transporter activity F 0 1 4 0 25 22 79 164 27.8 48.2 7.453 700 0.2.29.11.1.4.0 15078 hydrogen ion transporter activity F 5 21 32 23.8 65.6 22 73 154 30.1 47.4 7.941 701 0.2.29.11.1.4.0.3 8553 "hydrogen-exporting ATPase activity\, phosphorylative mechanism" F 3 8 12 37.5 66.7 3 8 12 37.5 66.7 3.443 702 0.2.29.11.1.4.0.8 8137 NADH dehydrogenase (ubiquinone) activity F 8 26 54 30.8 48.1 8 26 54 30.8 48.1 4.851 703 0.2.29.11.1.4.3 15081 sodium ion transporter activity F 0 2 2 0 100 8 29 57 27.6 50.9 4.443 704 0.2.29.11.1.4.3.0 8137 NADH dehydrogenase (ubiquinone) activity F 8 26 54 30.8 48.1 8 26 54 30.8 48.1 4.851 705 0.2.29.11.2 46873 metal ion transporter activity F 0 8 19 0 42.1 9 61 104 14.8 58.7 2.467 706 0.2.29.11.2.7 15081 sodium ion transporter activity F 0 2 2 0 100 8 29 57 27.6 50.9 4.443 707 0.2.29.11.2.7.0 8137 NADH dehydrogenase (ubiquinone) activity F 8 26 54 30.8 48.1 8 26 54 30.8 48.1 4.851 708 0.2.29.25 8565 protein transporter activity F 22 165 264 13.3 62.5 26 180 285 14.4 63.2 4.108 709 0.2.29.25.7 15450 protein translocase activity F 4 15 21 26.7 71.4 4 15 21 26.7 71.4 3.051