Molecular networks over-represented by E. bovis-regulated host cell molecules 8 (A) and 14 (B) days after in vitro infection. A list of significantly (p ≤ 0.05) regulated molecules in E. bovis-infected endothelial host cells 4, 8 and 14 days after infection was individually subjected to Ingenuity Pathway Analyses which generated highly significant networks displaying up-regulated molecules in red and down-regulated ones in green. (A) Network on molecules involved in cellular movement, immune cell trafficking and inflammatory response (8 days p.i.). (B) Network on molecules involved in cellular assembly and organisation, gene expression and infection mechanism (14 days p.i.). (A color figure is available at www.vetres.org.)