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Table I.
The number of viable and non-viable lambs born, and the mean gestation period for each group. In Experiments 1 and 2, ewes were infected per-os with 400 sporulated oocysts of PRU strain at mid-gestation. In Experiment 3, ewes were infected per-os with 100 sporulated oocysts of PRU strain at mid-gestation.
| Groups | Number of ewes | Number of lambs expected | Number of viable lambs (%) | Number of non-viable lambs |
Mean gestation period ± S.D. | |
|---|---|---|---|---|---|---|
| Early abortion* | Late abortion | |||||
| Exp. 1 (Romanov ewes) | ||||||
| Control | 11 | 11 | 0 (0) | 9 | 2 | 98 ± 16 |
| s.c. 105 Mic1-3KO | 11 | 21 | 13 (62) | 0 | 8 | 143 ± 4 |
| s.c. 105 S48 | 13 | 25 | 17 (68) | 0 | 8 | 146 ± 3 |
| Exp. 2 (Bizet ewes) | ||||||
| Control | 10 | 10 | 0 (0) | 6 | 4 | 122 ± 20 |
| s.c. 105 Mic1-3KO | 10 | 11 | 10 (91) | 0 | 1 | 158 ± 10 |
| s.c. 2x106 Mic1-3KO | 11 | 14 | 10 (71) | 0 | 4 | 154 ± 8 |
| Exp. 3 (Solognot ewes) | ||||||
| Control | 6 | 10 | 0 (0) | 1 | 9 | 123 ± 21 |
| s.c. 105 Mic1-3KO | 8 | 11 | 7 (64) | 0 | 4 | 137 ± 10 |
| i.p. 105 Mic1-3KO | 8 | 12 | 11 (92) | 0 | 1 | 143 ± 6 |
* Abortion before 105 days gestation.