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Table V.

Comparison of Hendra and Nipah virus infections in pigs.

Virus HeV NiV [11, 12]
Pigs, age, route and dose of inoculation Gottingen minipig, 5-month-old, IN 2.0 × 107 PFU/pig Landrace pig, 5-week-old, ON 6.6 × 107 PFU/pig Landrace pig, 5-week-old, ON 2.5 × 105 PFU/pig
Clinical signs Respiratory and possible neurological Respiratory Neurological and mild respiratory
Immunohistology Frequently noticeable syncytia Frequently noticeable syncytia Rarely noticeable syncytia
Virus shedding Nasal, oral, rectal, ocular Nasal, oral, rectal, ocular Nasal, pharyngeal, ocular
Virus distribution in tissues Respiratory, lymphoid, (CNS? – olfactory bulb) Respiratory, lymphoid Respiratory, lymphoid, CNS

CNS: Central nervous system; IN: intra-nasal; and ON: oral and nasal.