Open Access
Table V.
Comparison of Hendra and Nipah virus infections in pigs.
Virus | HeV | NiV [11, 12] | |
---|---|---|---|
Pigs, age, route and dose of inoculation | Gottingen minipig, 5-month-old, IN 2.0 × 107 PFU/pig | Landrace pig, 5-week-old, ON 6.6 × 107 PFU/pig | Landrace pig, 5-week-old, ON 2.5 × 105 PFU/pig |
Clinical signs | Respiratory and possible neurological | Respiratory | Neurological and mild respiratory |
Immunohistology | Frequently noticeable syncytia | Frequently noticeable syncytia | Rarely noticeable syncytia |
Virus shedding | Nasal, oral, rectal, ocular | Nasal, oral, rectal, ocular | Nasal, pharyngeal, ocular |
Virus distribution in tissues | Respiratory, lymphoid, (CNS? – olfactory bulb) | Respiratory, lymphoid | Respiratory, lymphoid, CNS |
CNS: Central nervous system; IN: intra-nasal; and ON: oral and nasal.