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Table I.
Summary of laboratory results, genotype and age distribution, and clinical status of the 72 scrapie-infected goats according to their PrPd distribution in brain and LRS tissues.
| PrPd IHC positive in |
|||
|---|---|---|---|
| Brain only (n = 4) | LRS only (n = 34) | Brain and LRS (n = 34) | |
| Other results | |||
| ELISA brain | (0) 0 (0) | (0) 0 (0) | (56) 19 (100) |
| WB brain | (0) 0 (0) | (0) 0 (0) | (56) 19 (100) |
| Vacuolation | (0) 0 (0) | (0) 0 (0) | (38) 13 (100) |
| Genotype at 142 | |||
| II | (0) 0 (0) | (76) 26 (65) | (41) 14 (35) |
| IM | (50) 2 (7) | (21) 7 (25) | (56) 19 (68) |
| MM | (50) 2 (50) | (3) 1 (25) | (3) 1 (25) |
| Age (months) | |||
| < 60 | (75) 3 (9) | (38) 13 (41) | (47) 16 (50) |
| > 60 | (25) 1 (4) | (62) 21 (61) | (53) 18 (35) |
| Clinical signs | |||
| Normal | (75) 3 (7) | (68) 23 (50) | (59) 20 (43) |
| Other | (0) 0 (0) | (9) 3 (50) | (9) 3 (50) |
| Inconclusive | (25) 1 (8) | (18) 6 (46) | (18) 6 (46) |
| Definite | (0) 0 (0) | (5) 2 (29) | (14) 5 (71) |
Results are indicated as number of animals falling in each group. Percentage in brackets to the left of the number refers to the total of goats in each IHC category (brain only, LRS only or brain and LRS). Percentage in brackets to the right of the number refers to the total of goats in each set of other results, genotype, age and clinical condition (rows).