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Table I.

Parasitological results per group. Groups (1, 2 or 3) with 10 animals per group, mean of cumulative EPG (S.E.), percentage reduction in EPG (mean), mean of worm burden (S.E.), percentage worm burden reduction (mean) and percentage of females. Animals were vaccinated in week 0, 2.5 and 5 with the cystatin bound fraction (group 1), total ES (group 2) or used as the adjuvant control group (group 3), challenged in week 6 with 10 000 L3H. contortus and slaughtered in week 10. The reductions are calculated based on the mean of group 3 (adjuvant control).

Group (n = 10) Cumulative EPG EPG reduction (%) Worm burden Worm burden reduction (%) Females (%)
1 43300 (11728) 32 2935 (2353) 36 55
2 59435 (12438) 6 4750 (2358) −3.6 57
3 63375 (20195) 4585 (2121) 58