Free Access

Table II.

Activity and predicted function of novel tick genes identified from uninfected and Rickettsia-infected D. variabilis using molecular techniques.

Predicted function Putative identification Expression during rickettsial infection
Adhesion or invasion Mucin-like protein ---
Clathrin adaptor protein +++
Tetraspanin +++
Protein inhibitor of signal transducer and activator of transcription 1/3 ---
ATPase of clathrin-coated vesicles +++
Catenin +++
Tick immune and stress response Ferritin +++
α-dehydrogenase reductase +++
Glutathione S-transferase +++
Nucleosome assembly protein +++
Cyclin A2 protein +++
Cu2+-transporting ATPase +++
Tubulin α chain +++
Defensin -/+
Lysozyme +
Serine protease NS
Prophenoloxidase-activating factor +++
Tick-host interactions α-2 macroglobulin +++
Salivary glue precursor +++
IgE-dependent histamine release factor +++
ENA vasodilator +++
Calreticulin ---
Histamine release factor +++
Unknown Probable elongation factor +++
Similar to Drosophila melanogaster CG17525 +++
Glycine-rich protein +++

NS: Not studied.