Free access
Vet. Res.
Volume 36, Number 3, May-June 2005
Emerging or re-emerging bacterial zoonoses
Page(s) 469 - 492
How to cite this article Vet. Res. (2005) 469-492
Vet. Res. 36 (2005) 469-492
DOI: 10.1051/vetres:2005004

Tick- and flea-borne rickettsial emerging zoonoses

Philippe Parolaa, Bernard Davoustb and Didier Raoulta

a  Unité des Rickettsies, CNRS UMR 6020, IFR 48, Faculté de Médecine, Université de la Méditerranée, 13385 Marseille Cedex 5, France
b  Direction Régionale du Service de Santé des Armées, BP 16, 69998 Lyon Armées, France

(Received 30 March 2004; accepted 5 August 2004)

Abstract - Between 1984 and 2004, nine more species or subspecies of spotted fever rickettsiae were identified as emerging agents of tick-borne rickettsioses throughout the world. Six of these species had first been isolated from ticks and later found to be pathogenic to humans. The most recent example is Rickettsia parkeri, recognized as a human pathogen more than 60 years after its initial isolation from ticks. A new spotted fever rickettsia, R. felis was also found to be associated with fleas and to be a human pathogen. Similarly, bacteria within the family Anaplasmataceae have been considered to be of veterinary importance only, yet three species have been implicated in human diseases in recent years, including Ehrlichia chaffeensis, the agent of human monocytic ehrlichiosis, Anaplasma phagocytophilum, the agent of human anaplasmosis (formerly known as "human granulocytic ehrlichiosis agent", E. equi and E. phagocytophila), and finally Ehrlichia ewingii, which causes granulocytic ehrlichiosis in humans. We present here an overview of the various tick- and flea-borne rickettsial zoonoses described in the last 20 years, focusing on the ecological, epidemiological and clinical aspects.

Key words: ticks / fleas / Rickettsia / Anaplasma / zoonoses

Corresponding author: Didier Raoult

© INRA, EDP Sciences 2005

What is OpenURL?

The OpenURL standard is a protocol for transmission of metadata describing the resource that you wish to access.

An OpenURL link contains article metadata and directs it to the OpenURL server of your choice. The OpenURL server can provide access to the resource and also offer complementary services (specific search engine, export of references...). The OpenURL link can be generated by different means.

  • If your librarian has set up your subscription with an OpenURL resolver, OpenURL links appear automatically on the abstract pages.
  • You can define your own OpenURL resolver with your EDPS Account.
    In this case your choice will be given priority over that of your library.
  • You can use an add-on for your browser (Firefox or I.E.) to display OpenURL links on a page (see You should disable this module if you wish to use the OpenURL server that you or your library have defined.